Published in Am J Respir Crit Care Med on October 01, 2010
Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source. Proc Natl Acad Sci U S A (2012) 1.62
The Asthma-COPD Overlap Syndrome: A Common Clinical Problem in the Elderly. J Allergy (Cairo) (2011) 1.49
Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling. Proc Natl Acad Sci U S A (2011) 1.25
Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair. PLoS One (2011) 1.20
Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β₁ is increased in chronic obstructive pulmonary disease. PLoS One (2011) 1.16
Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling. Pulm Circ (2013) 1.09
The pathogenesis of COPD and IPF: distinct horns of the same devil? Respir Res (2012) 1.06
Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol (2013) 0.99
The potential for resident lung mesenchymal stem cells to promote functional tissue regeneration: understanding microenvironmental cues. Cells (2012) 0.94
Aquaporin 5 regulates cigarette smoke induced emphysema by modulating barrier and immune properties of the epithelium. Tissue Barriers (2013) 0.87
A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin. Am J Respir Crit Care Med (2016) 0.87
Osteoporosis in chronic obstructive pulmonary disease. Clin Med Insights Circ Respir Pulm Med (2015) 0.86
Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/β-catenin-driven trans-differentiation of murine alveolar epithelial cells. Dis Model Mech (2015) 0.81
Fracture prevention in COPD patients; a clinical 5-step approach. Respir Res (2015) 0.80
Application of on-line nanoLC-IT-TOF in the identification of serum β-catenin complex in mice scald model. PLoS One (2012) 0.79
The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice. J Virol (2015) 0.78
A brief review of chronic obstructive pulmonary disease. Can Respir J (2012) 0.77
Take the Wnt out of the inflammatory sails: modulatory effects of Wnt in airway diseases. Lab Invest (2015) 0.77
Regenerative pathways and emphysema: a new paradigm? Am J Respir Crit Care Med (2011) 0.77
Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation. PLoS One (2014) 0.77
Atmin mediates kidney morphogenesis by modulating Wnt signaling. Hum Mol Genet (2014) 0.77
Wnt3a mitigates acute lung injury by reducing P2X7 receptor-mediated alveolar epithelial type I cell death. Cell Death Dis (2014) 0.77
Linking bronchopulmonary dysplasia to adult chronic lung diseases: role of WNT signaling. Mol Cell Pediatr (2016) 0.77
WNT/β-catenin signaling regulates cigarette smoke-induced airway inflammation via the PPARδ/p38 pathway. Lab Invest (2015) 0.77
Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: I. Effects on lung remodeling and pathology. Respir Res (2013) 0.76
'WNT-er is coming': WNT signalling in chronic lung diseases. Thorax (2017) 0.76
Roles of transcriptional factor 7 in production of inflammatory factors for lung diseases. J Transl Med (2015) 0.75
Wingless: developmentally important genes that respond adversely to smoking. Thorax (2013) 0.75
CDK14 expression is down-regulated by cigarette smoke in vivo and in vitro. Toxicol Lett (2015) 0.75
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD. J Exp Med (2016) 0.75
Cathepsin E promotes pulmonary emphysema via mitochondrial fission. Am J Pathol (2014) 0.75
Airflow limitation as a risk factor for low bone mineral density and hip fracture. Eur Clin Respir J (2016) 0.75
Commentary: A Breath of Fresh Air on the Mesenchyme: Impact of Impaired Mesenchymal Development on the Pathogenesis of Bronchopulmonary Dysplasia. Front Med (Lausanne) (2016) 0.75
Chronic obstructive pulmonary disease with mild airflow limitation: current knowledge and proposal for future research - a consensus document from six scientific societies. Int J Chron Obstruct Pulmon Dis (2017) 0.75
Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol (2004) 5.79
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet (2009) 4.56
Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med (2014) 3.50
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest (2009) 3.33
Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature. Circ Res (2007) 3.28
Corticosteroids and the risk of atrial fibrillation. Arch Intern Med (2006) 3.28
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Inhibition and role of let-7d in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2010) 3.02
Functional Wnt signaling is increased in idiopathic pulmonary fibrosis. PLoS One (2008) 2.94
Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice. Cell (2011) 2.51
Instillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in mice. Environ Health Perspect (2006) 2.51
Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung. Blood (2009) 2.50
Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema. Respir Res (2006) 2.40
Biodistribution of 1.4- and 18-nm gold particles in rats. Small (2008) 2.32
Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol (2009) 2.31
Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension. Hum Mutat (2006) 2.30
Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA. Am J Physiol Lung Cell Mol Physiol (2006) 2.29
Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2007) 2.26
New insights into the immunology of chronic obstructive pulmonary disease. Lancet (2011) 2.23
Retracted CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat Med (2010) 2.17
Oxidative stress and lipid mediators induced in alveolar macrophages by ultrafine particles. Free Radic Biol Med (2005) 2.12
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem (2009) 2.12
Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury. J Clin Invest (2009) 1.96
Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase. Am J Respir Cell Mol Biol (2005) 1.91
WNT signaling in lung disease: a failure or a regeneration signal? Am J Respir Cell Mol Biol (2009) 1.90
Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange. Proc Natl Acad Sci U S A (2006) 1.89
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax (2012) 1.88
Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the Rotterdam Study. Am J Respir Crit Care Med (2012) 1.87
Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs. Inhal Toxicol (2009) 1.78
Biodistribution of PEG-modified gold nanoparticles following intratracheal instillation and intravenous injection. Biomaterials (2010) 1.77
The impact of TGF-β on lung fibrosis: from targeting to biomarkers. Proc Am Thorac Soc (2012) 1.74
Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med (2002) 1.72
Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol (2006) 1.71
Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia? Am J Respir Cell Mol Biol (2004) 1.67
Oleic acid inhibits alveolar fluid reabsorption: a role in acute respiratory distress syndrome? Am J Respir Crit Care Med (2004) 1.66
Identification and characterization of human pulmonary dendritic cells. Am J Respir Cell Mol Biol (2004) 1.66
Efficient elimination of inhaled nanoparticles from the alveolar region: evidence for interstitial uptake and subsequent reentrainment onto airways epithelium. Environ Health Perspect (2007) 1.65
Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 1.63
Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source. Proc Natl Acad Sci U S A (2012) 1.62
Chronic obstructive pulmonary disease and cerebral microbleeds. The Rotterdam Study. Am J Respir Crit Care Med (2013) 1.57
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol (2008) 1.56
Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling. Circulation (2006) 1.55
Caveolin-1 facilitates mechanosensitive protein kinase B (Akt) signaling in vitro and in vivo. Circ Res (2005) 1.55
Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice. J Immunol (2006) 1.55
Leptin as regulator of pulmonary immune responses: involvement in respiratory diseases. Pulm Pharmacol Ther (2013) 1.54
Genetic basis of pulmonary arterial hypertension: current understanding and future directions. J Am Coll Cardiol (2004) 1.53
Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention. Thorax (2010) 1.52
Role of activin-A in cigarette smoke-induced inflammation and COPD. Eur Respir J (2013) 1.52
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet (2012) 1.52
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med (2012) 1.49
New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis. Lancet (2012) 1.47
Investigation of the antifibrotic effect of IFN-gamma on fibroblasts in a cell culture model of Peyronie's disease. Eur Urol (2007) 1.47
Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock. Thromb Haemost (2006) 1.46
Impact of TASK-1 in human pulmonary artery smooth muscle cells. Circ Res (2006) 1.44
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension. FASEB J (2005) 1.44
Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol (2007) 1.43
The role of cGMP in the physiological and molecular responses of the right ventricle to pressure overload. Exp Physiol (2013) 1.42
MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 1.42
The prognostic significance of inspiratory capacity in pulmonary arterial hypertension. Respiration (2014) 1.41
Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. Am J Pathol (2007) 1.39
Evaluation of angiogenesis using micro-computed tomography in a xenograft mouse model of lung cancer. Neoplasia (2009) 1.34
Deducing in vivo toxicity of combustion-derived nanoparticles from a cell-free oxidative potency assay and metabolic activation of organic compounds. Environ Health Perspect (2008) 1.32
Loss of RAGE in pulmonary fibrosis: molecular relations to functional changes in pulmonary cell types. Am J Respir Cell Mol Biol (2008) 1.31
Different roles for human lung dendritic cell subsets in pulmonary immune defense mechanisms. Am J Respir Cell Mol Biol (2006) 1.30
Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration. Eur J Pharm Biopharm (2010) 1.29
Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy. Circulation (2007) 1.28
Chronic lung disease in the preterm infant. Lessons learned from animal models. Am J Respir Cell Mol Biol (2014) 1.28
Matrix metalloproteinases in asthma and COPD. Curr Opin Pharmacol (2005) 1.27
Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required? Respir Res (2005) 1.25
From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases. BMC Pulm Med (2009) 1.24
Ultrafine particles exert prothrombotic but not inflammatory effects on the hepatic microcirculation in healthy mice in vivo. Circulation (2004) 1.22
Role of oxidative stress in ultrafine particle-induced exacerbation of allergic lung inflammation. Am J Respir Crit Care Med (2009) 1.22
Prevalence, incidence, and lifetime risk for the development of COPD in the elderly: the Rotterdam study. Chest (2009) 1.21
The lectin-like domain of tumor necrosis factor-alpha improves alveolar fluid balance in injured isolated rabbit lungs. Crit Care Med (2008) 1.20
Recent advances in late lung development and the pathogenesis of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol (2013) 1.20
Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation. J Immunol (2007) 1.17
Dendritic cells in chronic obstructive pulmonary disease: new players in an old game. Am J Respir Crit Care Med (2008) 1.15
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. Dev Dyn (2008) 1.15