Published in Cancer Biol Ther on August 03, 2007
Immunogenic cell death and DAMPs in cancer therapy. Nat Rev Cancer (2012) 3.76
Cancer Cells Expressing Toll-like Receptors and the Tumor Microenvironment. Cancer Microenviron (2009) 1.60
Reduced expression of Toll-like receptor 4 inhibits human breast cancer cells proliferation and inflammatory cytokines secretion. J Exp Clin Cancer Res (2010) 1.38
The Yin and Yang of Toll-like receptors in cancer. Oncogene (2013) 1.23
MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway. Mol Biol Cell (2012) 1.14
Toll-like receptor 5 (TLR5) expression is a novel predictive marker for recurrence and survival in squamous cell carcinoma of the tongue. Br J Cancer (2013) 1.06
Toll-like receptors and cancer, particularly oral squamous cell carcinoma. Front Immunol (2014) 0.99
MicroRNA-574-5p was pivotal for TLR9 signaling enhanced tumor progression via down-regulating checkpoint suppressor 1 in human lung cancer. PLoS One (2012) 0.95
TLR9 expression in glioma tissues correlated to glioma progression and the prognosis of GBM patients. BMC Cancer (2010) 0.93
Toll-like receptors and skin cancer. Front Immunol (2014) 0.90
Spontaneous production of immunoglobulin M in human epithelial cancer cells. PLoS One (2012) 0.88
Epigallocatechin-3-gallate suppresses proinflammatory cytokines and chemokines induced by Toll-like receptor 9 agonists in prostate cancer cells. J Inflamm Res (2014) 0.86
Gene silencing of Toll-like receptor 2 inhibits proliferation of human liver cancer cells and secretion of inflammatory cytokines. PLoS One (2012) 0.86
Autophagic activity measured in whole rat hepatocytes as the accumulation of a novel BHMT fragment (p10), generated in amphisomes by the asparaginyl proteinase, legumain. Autophagy (2011) 0.82
TLR9 signaling repressed tumor suppressor miR-7 expression through up-regulation of HuR in human lung cancer cells. Cancer Cell Int (2013) 0.79
CpG-oligodeoxynucleotides suppress the proliferation of A549 lung adenocarcinoma cells via toll-like receptor 9 signaling and upregulation of Runt-related transcription factor 3 expression. Biomed Rep (2014) 0.79
Prognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patients. PLoS One (2014) 0.78
IL-17A/IL-17RA interaction promoted metastasis of osteosarcoma cells. Cancer Biol Ther (2012) 0.78
The stimulatory activity of plasma in patients with advanced non-small cell lung cancer requires TLR-stimulating nucleic acid immunoglobulin complexes and discriminates responsiveness to chemotherapy. Cancer Cell Int (2014) 0.75
Toll-like receptor 4 as a predictor of clinical outcomes of estrogen receptor-negative breast cancer in Saudi women. Onco Targets Ther (2017) 0.75
Bioinformatics analysis of differentially expressed pathways related to the metastatic characteristics of osteosarcoma. Int J Mol Med (2016) 0.75
Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol (2010) 5.92
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. Ann Neurol (2008) 5.55
Ghrelin controls hippocampal spine synapse density and memory performance. Nat Neurosci (2006) 4.25
Rationally designed, polymeric, extended metal-ciprofloxacin complexes. Chemistry (2005) 3.56
Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Invest (2008) 3.53
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85
Decreased regional homogeneity in schizophrenia: a resting state functional magnetic resonance imaging study. Neuroreport (2006) 2.08
Long noncoding RNA: an emerging paradigm of cancer research. Tumour Biol (2013) 2.07
Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron (2005) 2.07
Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis. Int J Cancer (2011) 2.01
Obesity and hypertriglyceridemia produce cognitive impairment. Endocrinology (2008) 1.94
A functional genetic variant in microRNA-196a2 is associated with increased susceptibility of lung cancer in Chinese. Cancer Epidemiol Biomarkers Prev (2009) 1.93
Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels. J Neurosci (2008) 1.92
Characterization of MADS-domain transcription factor complexes in Arabidopsis flower development. Proc Natl Acad Sci U S A (2012) 1.83
Entangled coordination networks with inherent features of polycatenation, polythreading, and polyknotting. Angew Chem Int Ed Engl (2005) 1.81
Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis. J Clin Invest (2013) 1.81
The Putative RNA-dependent RNA polymerase RDR6 acts synergistically with ASYMMETRIC LEAVES1 and 2 to repress BREVIPEDICELLUS and MicroRNA165/166 in Arabidopsis leaf development. Plant Cell (2005) 1.80
Average gene length is highly conserved in prokaryotes and eukaryotes and diverges only between the two kingdoms. Mol Biol Evol (2006) 1.67
Hospitalizations for pediatric stone disease in United States, 2002-2007. J Urol (2010) 1.62
Autoantibody induction by DNA-containing immune complexes requires HMGB1 with the TLR2/microRNA-155 pathway. J Immunol (2013) 1.61
Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease. J Neurosci (2006) 1.59
Genome of the Chinese tree shrew. Nat Commun (2013) 1.55
Microtubule-dependent distribution of mRNA in adult cardiocytes. Am J Physiol Heart Circ Physiol (2008) 1.55
Hierarchical MnMoO(4)/CoMoO(4) heterostructured nanowires with enhanced supercapacitor performance. Nat Commun (2011) 1.55
Smoking and mortality in a prospective cohort study of elderly Chinese in Hong Kong. Addiction (2014) 1.52
Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. Nat Genet (2012) 1.49
Neurite outgrowth and in vivo sensory innervation mediated by a Ca(V)2.2-laminin beta 2 stop signal. J Neurosci (2008) 1.49
Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population. Carcinogenesis (2009) 1.48
Ovarian torsion: diagnosis of inclusion mandates earlier intervention. J Pediatr Surg (2012) 1.43
An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research. Thromb Res (2005) 1.43
FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons. Neurobiol Dis (2008) 1.43
White matter abnormalities in first-episode, treatment-naive young adults with major depressive disorder. Am J Psychiatry (2007) 1.43
Optimal delivery of minocycline to the brain: implication for human studies of acute neuroprotection. Exp Neurol (2004) 1.40
Impaired hippocampal synaptic transmission and plasticity in mice lacking fibroblast growth factor 14. Mol Cell Neurosci (2007) 1.40
Characterization of acid-sensing ion channels in dorsal horn neurons of rat spinal cord. J Biol Chem (2004) 1.38
An ACTH- and ATP-regulated background K+ channel in adrenocortical cells is TREK-1. J Biol Chem (2002) 1.37
Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD. Cell (2012) 1.37
Cardiac-specific expression and hypertrophic upregulation of the feline Na(+)-Ca(2+) exchanger gene H1-promoter in a transgenic mouse model. Circ Res (2002) 1.35
Interlocked and interdigitated architectures from self-assembly of long flexible ligands and cadmium salts. Angew Chem Int Ed Engl (2004) 1.35
CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer. Tumour Biol (2014) 1.34
Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14. Neurobiol Dis (2007) 1.34
Long-term effect of stent placement in 115 patients with Budd-Chiari syndrome. World J Gastroenterol (2003) 1.34
Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke. BMC Neurosci (2009) 1.33
Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma. Tumour Biol (2014) 1.32
Enhanced contextual fear memory in central serotonin-deficient mice. Proc Natl Acad Sci U S A (2008) 1.31
Ischemic postconditioning protects remodeled myocardium via the PI3K-PKB/Akt reperfusion injury salvage kinase pathway. Cardiovasc Res (2006) 1.31
WOX11 and 12 are involved in the first-step cell fate transition during de novo root organogenesis in Arabidopsis. Plant Cell (2014) 1.30
A series of new organic-inorganic molybdenum arsenate complexes based on [(ZnO6)(As3O3)2Mo6O18]4- and [HxAs2Mo6O26](6-x)- clusters as SBUs. Inorg Chem (2007) 1.30
A membrane-bound NAC transcription factor, ANAC017, mediates mitochondrial retrograde signaling in Arabidopsis. Plant Cell (2013) 1.26
The natural history and treatment of epilepsy in a murine model of tuberous sclerosis. Epilepsia (2007) 1.26
Role of HTRA1, a serine protease, in the progression of articular cartilage degeneration. Histol Histopathol (2010) 1.24
DNA repair gene XRCC1 and XPD polymorphisms and risk of lung cancer in a Chinese population. Carcinogenesis (2002) 1.22
c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells. J Biol Chem (2002) 1.22
Relationship of arterial stiffness and early mild diastolic heart failure in general middle and aged population. Eur Heart J (2010) 1.21
Lung autotransplantation technique in the treatment for central lung cancer of upper lobe. J Thorac Oncol (2008) 1.21
Occurrence and transport of tetracycline, sulfonamide, quinolone, and macrolide antibiotics in the Haihe River Basin, China. Environ Sci Technol (2011) 1.20
Phenological responses of Ulmus pumila (Siberian Elm) to climate change in the temperate zone of China. Int J Biometeorol (2011) 1.19
Notch-induced rat and human bone marrow stromal cell grafts reduce ischemic cell loss and ameliorate behavioral deficits in chronic stroke animals. Stem Cells Dev (2009) 1.18
Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis. J Pharmacol Exp Ther (2003) 1.18
In-depth temporal transcriptome profiling reveals a crucial developmental switch with roles for RNA processing and organelle metabolism that are essential for germination in Arabidopsis. Plant Physiol (2011) 1.17
Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection. J Hypertens (2006) 1.17
Hydrothermal syntheses, crystal structures and magnetic properties of two copper(II) complexes involved in situ ligand synthesis. Dalton Trans (2007) 1.17
Factors characterizing Staphylococcus epidermidis invasiveness determined by comparative genomics. Infect Immun (2005) 1.17
Plant fertility defects induced by the enhanced expression of microRNA167. Cell Res (2006) 1.17
Functional polymorphisms of matrix metalloproteinase-9 are associated with risk of occurrence and metastasis of lung cancer. Clin Cancer Res (2005) 1.16
Electrophysiological properties of human hypothalamic hamartomas. Ann Neurol (2005) 1.16
Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity. J Neurosci (2007) 1.15
Neural progenitor NT2N cell lines from teratocarcinoma for transplantation therapy in stroke. Prog Neurobiol (2008) 1.15
Prognostic value of survivin in patients with non-small cell lung carcinoma: a systematic review with meta-analysis. PLoS One (2012) 1.15
Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population. Int J Cancer (2006) 1.14
beta-Amyloid directly inhibits human alpha4beta2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells. J Biol Chem (2004) 1.14
Schizophrenia patients and their healthy siblings share disruption of white matter integrity in the left prefrontal cortex and the hippocampus but not the anterior cingulate cortex. Schizophr Res (2009) 1.13
Occurrence of sulfonamide and tetracycline-resistant bacteria and resistance genes in aquaculture environment. Water Res (2012) 1.13
Single beta-AgVO3 nanowire H2S sensor. Nano Lett (2010) 1.13
Trends in antibiotic resistance genes occurrence in the Haihe River, China. Environ Sci Technol (2010) 1.12
Differential impairment of regulatory T cells rather than effector T cells by paclitaxel-based chemotherapy. Clin Immunol (2008) 1.12
Effect of carbon matrix dimensions on the electrochemical properties of Na3V2(PO4)3 nanograins for high-performance symmetric sodium-ion batteries. Adv Mater (2014) 1.11
Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells. Mol Biol Rep (2008) 1.11
SET DOMAIN GROUP25 encodes a histone methyltransferase and is involved in FLOWERING LOCUS C activation and repression of flowering. Plant Physiol (2009) 1.11
Osteocalcin reverses endoplasmic reticulum stress and improves impaired insulin sensitivity secondary to diet-induced obesity through nuclear factor-κB signaling pathway. Endocrinology (2013) 1.11
Behavioral and histological characterization of intrahippocampal grafts of human bone marrow-derived multipotent progenitor cells in neonatal rats with hypoxic-ischemic injury. Cell Transplant (2006) 1.10
Reprogramming of H3K27me3 is critical for acquisition of pluripotency from cultured Arabidopsis tissues. PLoS Genet (2012) 1.10
Electrophysiological, pharmacological, and molecular evidence for alpha7-nicotinic acetylcholine receptors in rat midbrain dopamine neurons. J Pharmacol Exp Ther (2004) 1.08
Prefrontal white matter abnormalities in young adult with major depressive disorder: a diffusion tensor imaging study. Brain Res (2007) 1.08
Antistress effect of TRPV1 channel on synaptic plasticity and spatial memory. Biol Psychiatry (2008) 1.07
Binocular status after surgery for constant and intermittent exotropia. Am J Ophthalmol (2006) 1.07
White matter integrity of the whole brain is disrupted in first-episode schizophrenia. Neuroreport (2006) 1.07
Genetic polymorphisms in the precursor MicroRNA flanking region and non-small cell lung cancer survival. Am J Respir Crit Care Med (2010) 1.06
Exposure to chronic constant light impairs spatial memory and influences long-term depression in rats. Neurosci Res (2007) 1.06
Inhibition of tumor necrosis factor-alpha-converting enzyme by a selective antagonist protects brain from focal ischemic injury in rats. Mol Pharmacol (2004) 1.06
Conversion of Staphylococcus epidermidis strains from commensal to invasive by expression of the ica locus encoding production of biofilm exopolysaccharide. Infect Immun (2005) 1.06
Electrospun ultralong hierarchical vanadium oxide nanowires with high performance for lithium ion batteries. Nano Lett (2010) 1.06
Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy. Clin Cancer Res (2012) 1.05
Bell-shaped D-serine actions on hippocampal long-term depression and spatial memory retrieval. Cereb Cortex (2008) 1.05
Nucleotide excision repair gene ERCC1 polymorphisms contribute to cancer susceptibility: a meta-analysis. Mutagenesis (2011) 1.05
A physiological role for amyloid-beta protein:enhancement of learning and memory. J Alzheimers Dis (2010) 1.04
Early versus delayed administration of norepinephrine in patients with septic shock. Crit Care (2014) 1.04
Transplantation of bone marrow-derived stem cells: a promising therapy for stroke. Cell Transplant (2007) 1.04
Lead exposure through gestation-only caused long-term learning/memory deficits in young adult offspring. Exp Neurol (2003) 1.03