Tim Wiltshire

Author PubWeight™ 148.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A 2004 44.81
2 Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A 2002 25.47
3 The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet 2004 9.37
4 Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet 2005 6.91
5 The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 2006 5.83
6 Melanopsin is required for non-image-forming photic responses in blind mice. Science 2003 4.22
7 Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse. PLoS Biol 2004 4.08
8 Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome Res 2008 3.54
9 Genetical genomics: spotlight on QTL hotspots. PLoS Genet 2008 2.63
10 Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet 2008 2.32
11 c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiation. Dev Cell 2005 2.30
12 Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse. Genome Res 2006 2.26
13 Genomewide association analysis in diverse inbred mice: power and population structure. Genetics 2007 2.01
14 A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function. J Neurosci 2007 1.90
15 Comparative analysis of haplotype association mapping algorithms. BMC Bioinformatics 2006 1.55
16 A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. PLoS One 2009 1.44
17 A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells. Proc Natl Acad Sci U S A 2009 1.39
18 Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans. Am J Hum Genet 2009 1.37
19 Genetic architecture of voluntary exercise in an advanced intercross line of mice. Physiol Genomics 2010 1.30
20 Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2. Gastroenterology 2006 1.27
21 Genetic dissection of a key reproductive barrier between nascent species of house mice. Genetics 2011 1.25
22 Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity. Proc Natl Acad Sci U S A 2004 1.20
23 A novel approach to investigate tissue-specific trinucleotide repeat instability. BMC Syst Biol 2010 1.20
24 Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice. J Bone Miner Res 2005 1.17
25 Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease. Hum Mol Genet 2005 1.13
26 Extensive recombination rate variation in the house mouse species complex inferred from genetic linkage maps. Genome Res 2010 1.09
27 The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain. J Exp Med 2012 1.07
28 Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation. PLoS One 2012 0.99
29 Genetically based resistance to the antiinflammatory effects of methotrexate in the air-pouch model of acute inflammation. Arthritis Rheum 2005 0.98
30 Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice. Elife 2013 0.98
31 The genetic contribution to heart rate and heart rate variability in quiescent mice. Am J Physiol Heart Circ Physiol 2008 0.96
32 A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function. Mol Cell 2009 0.96
33 The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6-/- mice. Blood 2007 0.95
34 A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen. Learn Mem 2006 0.93
35 Quantitative trait locus and haplotype mapping in closely related inbred strains identifies a locus for open field behavior. Mamm Genome 2010 0.93
36 An interaction between genetic factors and gender determines the magnitude of the inflammatory response in the mouse air pouch model of acute inflammation. Inflammation 2005 0.91
37 A novel allele of myosin VIIa reveals a critical function for the C-terminal FERM domain for melanosome transport in retinal pigment epithelial cells. J Neurosci 2009 0.91
38 Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. Psychopharmacology (Berl) 2011 0.90
39 Integrative analysis of low- and high-resolution eQTL. PLoS One 2010 0.88
40 Coordinated diurnal regulation of genes from the Dlk1-Dio3 imprinted domain: implications for regulation of clusters of non-paralogous genes. Hum Mol Genet 2007 0.86
41 Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-gamma as contributing to enhanced malaria survival. PLoS One 2010 0.84
42 In vitro and in vivo mouse models for pharmacogenetic studies. Methods Mol Biol 2013 0.78
43 Characterization of Highper, an ENU-induced mouse mutant with abnormal psychostimulant and stress responses. Psychopharmacology (Berl) 2012 0.76
44 Can we find the genes involved in complex traits? Genome Biol 2004 0.76
45 Molecular genetic mechanisms of allelic specific regulation of murine Comt expression. Pain 2015 0.75
46 Relax, you won't feel the pain. Nat Neurosci 2011 0.75
47 Databases of free expression. Mamm Genome 2006 0.75
48 Institutional profile. UNC Institute for Pharmacogenomics and Individualized Therapy: interdisciplinary research for individual care. Pharmacogenomics 2010 0.75