Published in Nat Protoc on January 01, 2007
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7. Nat Protoc (2008) 16.53
Towards automated crystallographic structure refinement with phenix.refine. Acta Crystallogr D Biol Crystallogr (2012) 11.31
Super-resolution biomolecular crystallography with low-resolution data. Nature (2010) 6.14
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. Proc Natl Acad Sci U S A (2009) 3.92
Averaged kick maps: less noise, more signal... and probably less bias. Acta Crystallogr D Biol Crystallogr (2009) 3.62
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin. Proc Natl Acad Sci U S A (2011) 3.51
Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature (2008) 3.44
Structural basis of ligand binding by a c-di-GMP riboswitch. Nat Struct Mol Biol (2009) 3.28
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature (2009) 3.13
Current status of the AMOEBA polarizable force field. J Phys Chem B (2010) 3.06
Three-dimensional structures of membrane proteins from genomic sequencing. Cell (2012) 3.02
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature (2012) 2.97
The minimum crystal size needed for a complete diffraction data set. Acta Crystallogr D Biol Crystallogr (2010) 2.94
Lipidic phase membrane protein serial femtosecond crystallography. Nat Methods (2012) 2.76
Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell (2008) 2.69
Conformational coupling across the plasma membrane in activation of the EGF receptor. Cell (2013) 2.49
Crystal structure of the entire respiratory complex I. Nature (2013) 2.34
ACPYPE - AnteChamber PYthon Parser interfacE. BMC Res Notes (2012) 2.30
Structural aspects of messenger RNA reading frame maintenance by the ribosome. Nat Struct Mol Biol (2010) 2.30
Cryo-EM structure of the mature dengue virus at 3.5-Å resolution. Nat Struct Mol Biol (2012) 2.27
Structural basis for the activation of PPARgamma by oxidized fatty acids. Nat Struct Mol Biol (2008) 2.25
Alternating access in maltose transporter mediated by rigid-body rotations. Mol Cell (2009) 2.20
Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans. Nature (2012) 2.16
Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase. Nature (2009) 2.15
Structure of the toxic core of α-synuclein from invisible crystals. Nature (2015) 2.14
NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat Struct Mol Biol (2010) 2.12
Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies. J Virol (2014) 2.09
X-ray structure of the mammalian GIRK2-βγ G-protein complex. Nature (2013) 2.02
Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein. Nature (2010) 2.01
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response. Nature (2012) 1.99
Structure of the membrane domain of respiratory complex I. Nature (2011) 1.93
Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins. Proc Natl Acad Sci U S A (2012) 1.89
Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. Nature (2011) 1.89
Structural basis for protein antiaggregation activity of the trigger factor chaperone. Science (2014) 1.86
Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature (2015) 1.83
Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2. Proc Natl Acad Sci U S A (2009) 1.82
Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2. Structure (2010) 1.79
Recognition of a signal peptide by the signal recognition particle. Nature (2010) 1.77
Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity. Nat Struct Mol Biol (2010) 1.77
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA. Nucleic Acids Res (2009) 1.72
Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states. Nat Struct Mol Biol (2015) 1.70
Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs. Nat Struct Mol Biol (2010) 1.70
Structures of receptor complexes of a North American H7N2 influenza hemagglutinin with a loop deletion in the receptor binding site. PLoS Pathog (2010) 1.69
Structure of the AcrAB-TolC multidrug efflux pump. Nature (2014) 1.66
Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution. Acta Crystallogr D Biol Crystallogr (2012) 1.64
Crystal structure of group II chaperonin in the open state. Structure (2010) 1.62
Snapshots of the maltose transporter during ATP hydrolysis. Proc Natl Acad Sci U S A (2011) 1.62
Structural basis of receptor sharing by interleukin 17 cytokines. Nat Immunol (2009) 1.60
X-ray structure determination at low resolution. Acta Crystallogr D Biol Crystallogr (2009) 1.60
Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel. Nature (2011) 1.60
The octamer is the major form of CENP-A nucleosomes at human centromeres. Nat Struct Mol Biol (2013) 1.59
Towards a pharmacophore for amyloid. PLoS Biol (2011) 1.58
An unusual role for a mobile flavin in StaC-like indolocarbazole biosynthetic enzymes. Chem Biol (2012) 1.56
Structure of bacteriophage SPP1 head-to-tail connection reveals mechanism for viral DNA gating. Proc Natl Acad Sci U S A (2009) 1.56
Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation. EMBO Rep (2011) 1.55
Sequence co-evolution gives 3D contacts and structures of protein complexes. Elife (2014) 1.55
Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore. Nat Struct Mol Biol (2009) 1.55
Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanism. Nat Struct Mol Biol (2008) 1.54
Structure and function of an NADPH-cytochrome P450 oxidoreductase in an open conformation capable of reducing cytochrome P450. J Biol Chem (2009) 1.54
The structure of the ankyrin-binding site of beta-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties. Blood (2009) 1.54
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nat Struct Mol Biol (2011) 1.53
A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36. Genes Dev (2014) 1.53
MicroED data collection and processing. Acta Crystallogr A Found Adv (2015) 1.50
Structural basis for the mechanism of respiratory complex I. J Biol Chem (2009) 1.49
Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. EMBO J (2011) 1.48
Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region. J Biol Chem (2008) 1.48
Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A. Nat Struct Mol Biol (2008) 1.48
Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses. Nat Struct Mol Biol (2010) 1.46
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. J Biol Chem (2013) 1.46
Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes. Proc Natl Acad Sci U S A (2010) 1.46
Structure of Sputnik, a virophage, at 3.5-Å resolution. Proc Natl Acad Sci U S A (2012) 1.45
Crystal structure of the DNA-recognition component of the bacterial virus Sf6 genome-packaging machine. Proc Natl Acad Sci U S A (2010) 1.42
Physicochemical characterization of Remsima. MAbs (2014) 1.42
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat Struct Mol Biol (2010) 1.42
Structural characterization of the dual glycan binding adeno-associated virus serotype 6. J Virol (2010) 1.42
Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proc Natl Acad Sci U S A (2010) 1.39
Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin. J Biol Chem (2009) 1.38
Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. J Biol Chem (2009) 1.37
A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC. J Exp Med (2011) 1.34
Structural insights into mechanisms of the small RNA methyltransferase HEN1. Nature (2009) 1.34
Unusual diheme conformation of the heme-degrading protein from Mycobacterium tuberculosis. J Mol Biol (2009) 1.33
Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes. Nat Struct Mol Biol (2010) 1.33
DNA binding to RecD: role of the 1B domain in SF1B helicase activity. EMBO J (2008) 1.32
Structural insights into the assembly and activation of IL-1β with its receptors. Nat Immunol (2010) 1.32
Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife (2013) 1.31
Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold. J Mol Biol (2011) 1.29
Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair. Genes Dev (2008) 1.27
Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of alpha- and PPII-helices. Proc Natl Acad Sci U S A (2010) 1.27
Structure of epi-isozizaene synthase from Streptomyces coelicolor A3(2), a platform for new terpenoid cyclization templates. Biochemistry (2010) 1.27
Atomic structure of T6SS reveals interlaced array essential to function. Cell (2015) 1.26
Regulation of interdomain interactions by calmodulin in inducible nitric-oxide synthase. J Biol Chem (2009) 1.25
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane. FASEB J (2011) 1.25
Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain. J Virol (2009) 1.23
Blind testing of routine, fully automated determination of protein structures from NMR data. Structure (2012) 1.23
Structural basis for the cAMP-dependent gating in the human HCN4 channel. J Biol Chem (2010) 1.22
Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife (2013) 1.22
Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity. J Mol Biol (2010) 1.22
Structure and insights into the function of a Ca(2+)-activated Cl(-) channel. Nature (2014) 1.21
Conformation switching of clathrin light chain regulates clathrin lattice assembly. Dev Cell (2010) 1.21
Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex. EMBO J (2012) 1.21