Published in Nat Struct Mol Biol on March 07, 2010
The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription. PLoS Pathog (2010) 1.57
Dual host-virus arms races shape an essential housekeeping protein. PLoS Biol (2013) 1.22
The major determinant of attenuation in mice of the Candid1 vaccine for Argentine hemorrhagic fever is located in the G2 glycoprotein transmembrane domain. J Virol (2011) 1.19
How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc Natl Acad Sci U S A (2011) 1.12
The curious case of arenavirus entry, and its inhibition. Viruses (2012) 1.11
Junín virus pathogenesis and virus replication. Viruses (2012) 1.07
Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs. PLoS Pathog (2012) 1.05
Junin virus infects mouse cells and induces innate immune responses. J Virol (2011) 1.05
Transferrin receptor 1 in the zoonosis and pathogenesis of New World hemorrhagic fever arenaviruses. Curr Opin Microbiol (2011) 1.03
A virus-binding hot spot on human angiotensin-converting enzyme 2 is critical for binding of two different coronaviruses. J Virol (2011) 1.03
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection. PLoS Pathog (2015) 0.96
Structure of a zinc-binding domain in the Junin virus envelope glycoprotein. J Biol Chem (2010) 0.95
Binding site on the transferrin receptor for the parvovirus capsid and effects of altered affinity on cell uptake and infection. J Virol (2010) 0.94
An antibody recognizing the apical domain of human transferrin receptor 1 efficiently inhibits the entry of all new world hemorrhagic Fever arenaviruses. J Virol (2012) 0.94
Molecular Mechanism for LAMP1 Recognition by Lassa Virus. J Virol (2015) 0.93
Cells under siege: viral glycoprotein interactions at the cell surface. J Struct Biol (2011) 0.91
Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike. PLoS Pathog (2016) 0.90
A specific interaction of small molecule entry inhibitors with the envelope glycoprotein complex of the Junín hemorrhagic fever arenavirus. J Biol Chem (2010) 0.89
Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV. Nat Struct Mol Biol (2016) 0.87
Machupo virus glycoprotein determinants for human transferrin receptor 1 binding and cell entry. PLoS One (2011) 0.86
Crystal structure of Venezuelan hemorrhagic fever virus fusion glycoprotein reveals a class 1 postfusion architecture with extensive glycosylation. J Virol (2013) 0.85
Lassa-vesicular stomatitis chimeric virus safely destroys brain tumors. J Virol (2015) 0.84
Structure and dynamics of drug carriers and their interaction with cellular receptors: focus on serum transferrin. Adv Drug Deliv Rev (2012) 0.84
Human and host species transferrin receptor 1 use by North American arenaviruses. J Virol (2014) 0.82
Molecular Basis for Antibody-Mediated Neutralization of New World Hemorrhagic Fever Mammarenaviruses. Cell Host Microbe (2015) 0.82
Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses. Expert Opin Drug Discov (2012) 0.82
Immunology of bats and their viruses: challenges and opportunities. Viruses (2014) 0.82
LCMV glycosylation modulates viral fitness and cell tropism. PLoS One (2013) 0.81
Virions at the gates: receptors and the host-virus arms race. PLoS Biol (2013) 0.79
A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry. Mol Ther Nucleic Acids (2016) 0.78
Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses. J Virol (2015) 0.77
Nonhuman transferrin receptor 1 is an efficient cell entry receptor for Ocozocoautla de Espinosa virus. J Virol (2013) 0.77
Differences in glycoprotein complex (GPC) receptor binding site accessibility prompt poor cross-reactivity of neutralizing antibodies between closely related arenaviruses. J Virol (2017) 0.75
A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 Protease. J Virol (2015) 0.75
Native functionality and therapeutic targeting of arenaviral glycoproteins. Curr Opin Virol (2016) 0.75
A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles. mSphere (2016) 0.75
Human antibody pieces together the puzzle of the trimeric Lassa virus surface antigen. Nat Struct Mol Biol (2017) 0.75
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
Phaser crystallographic software. J Appl Crystallogr (2007) 108.34
PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr D Biol Crystallogr (2002) 53.61
Jalview Version 2--a multiple sequence alignment editor and analysis workbench. Bioinformatics (2009) 31.84
The Jalview Java alignment editor. Bioinformatics (2004) 21.74
Version 1.2 of the Crystallography and NMR system. Nat Protoc (2007) 13.01
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature (2003) 8.77
Viral membrane fusion. Nat Struct Mol Biol (2008) 8.54
Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 7.29
Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoprotein. Cell (2000) 4.88
Structure of the human transferrin receptor-transferrin complex. Cell (2004) 3.64
Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses. Nature (2007) 3.06
Phylogenetic analysis of the Arenaviridae: patterns of virus evolution and evidence for cospeciation between arenaviruses and their rodent hosts. Mol Phylogenet Evol (1997) 2.36
Chapare virus, a newly discovered arenavirus isolated from a fatal hemorrhagic fever case in Bolivia. PLoS Pathog (2008) 2.23
Crystal structure of the ectodomain of human transferrin receptor. Science (1999) 2.19
Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor. Nature (2000) 2.14
The phylogeny of New World (Tacaribe complex) arenaviruses. Virology (1996) 2.11
Arenaviruses other than Lassa virus. Antiviral Res (2003) 1.86
Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor. EMBO Rep (2003) 1.85
Role of the stable signal peptide of Junín arenavirus envelope glycoprotein in pH-dependent membrane fusion. J Virol (2006) 1.65
New arenavirus isolated in Brazil. Lancet (1994) 1.60
Transferrin receptor 1. Int J Biochem Cell Biol (2004) 1.50
Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses. Proc Natl Acad Sci U S A (2008) 1.47
Arenaviruses: protein structure and function. Curr Top Microbiol Immunol (2002) 1.38
Host-species transferrin receptor 1 orthologs are cellular receptors for nonpathogenic new world clade B arenaviruses. PLoS Pathog (2009) 1.37
Cell entry by human pathogenic arenaviruses. Cell Microbiol (2007) 1.25
Description of Guanarito virus (Arenaviridae: Arenavirus), the etiologic agent of Venezuelan hemorrhagic fever. Am J Trop Med Hyg (1994) 1.21
Distinct requirements for signal peptidase processing and function in the stable signal peptide subunit of the Junín virus envelope glycoprotein. Virology (2006) 1.19
Genetic analysis of heptad-repeat regions in the G2 fusion subunit of the Junín arenavirus envelope glycoprotein. Virology (2005) 1.17
Molecular phylogeny of the arenaviruses. Curr Top Microbiol Immunol (2002) 1.17
Phylogeny and evolution of old world arenaviruses. Virology (2006) 1.15
Unusual molecular architecture of the machupo virus attachment glycoprotein. J Virol (2009) 1.12
Mapping the landscape of the lymphocytic choriomeningitis virus stable signal peptide reveals novel functional domains. J Virol (2007) 1.09
Arenaviruses. I. The epidemiology molecular and cell biology of arenaviruses. Introduction. Curr Top Microbiol Immunol (2002) 1.08
X-ray structure of a protein-conducting channel. Nature (2003) 9.20
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature (2003) 8.77
Structure of an unliganded simian immunodeficiency virus gp120 core. Nature (2005) 8.30
Structure of the dengue virus envelope protein after membrane fusion. Nature (2004) 7.97
The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell (2009) 7.88
A ligand-binding pocket in the dengue virus envelope glycoprotein. Proc Natl Acad Sci U S A (2003) 7.76
Crystal structure of glycoprotein B from herpes simplex virus 1. Science (2006) 5.57
Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature (2005) 5.44
Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction. Proc Natl Acad Sci U S A (2008) 5.33
Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120. Proc Natl Acad Sci U S A (2004) 5.15
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe (2009) 5.12
Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science (2005) 4.97
The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol (2005) 4.81
The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nat Struct Mol Biol (2006) 4.62
Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature (2004) 4.48
An atomic model of the interferon-beta enhanceosome. Cell (2007) 4.22
Structure and function of an essential component of the outer membrane protein assembly machine. Science (2007) 3.85
B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nat Biotechnol (2012) 3.69
Structure of the human transferrin receptor-transferrin complex. Cell (2004) 3.64
A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2. J Biol Chem (2003) 3.60
Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein. J Virol (2005) 3.58
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin. Proc Natl Acad Sci U S A (2011) 3.51
XMAP215 is a processive microtubule polymerase. Cell (2008) 3.33
Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog (2011) 3.26
Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association. Proc Natl Acad Sci U S A (2004) 3.23
Role of HIV membrane in neutralization by two broadly neutralizing antibodies. Proc Natl Acad Sci U S A (2009) 3.19
The broad-spectrum antiviral functions of IFIT and IFITM proteins. Nat Rev Immunol (2012) 3.17
Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2. EMBO J (2005) 3.14
Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation. Proc Natl Acad Sci U S A (2004) 3.10
Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses. Nature (2007) 3.06
Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120. Cell (2003) 3.03
Molecular organization of the Ndc80 complex, an essential kinetochore component. Proc Natl Acad Sci U S A (2005) 3.01
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking. Blood (2005) 2.95
Beam-induced motion of vitrified specimen on holey carbon film. J Struct Biol (2012) 2.84
Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure (2012) 2.80
RNA synthesis in a cage--structural studies of reovirus polymerase lambda3. Cell (2002) 2.74
Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proc Natl Acad Sci U S A (2009) 2.65
Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor. J Biol Chem (2006) 2.56
Subunit interactions in bovine papillomavirus. Proc Natl Acad Sci U S A (2010) 2.51
Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy. Curr Opin Struct Biol (2011) 2.47
Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate. J Virol (2002) 2.43
The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site. EMBO J (2002) 2.41
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells. J Biol Chem (2005) 2.36
Single-particle kinetics of influenza virus membrane fusion. Proc Natl Acad Sci U S A (2008) 2.32
Crystal structure of the clathrin adaptor protein 1 core. Proc Natl Acad Sci U S A (2004) 2.28
Atomic model of the papillomavirus capsid. EMBO J (2002) 2.27
Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3. Cell (2002) 2.24
Evolution of a TRIM5-CypA splice isoform in old world monkeys. PLoS Pathog (2008) 2.20
Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. J Mol Biol (2006) 2.17
Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure (2008) 2.13
Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein. Structure (2005) 2.13
Structural rearrangements in the membrane penetration protein of a non-enveloped virus. Nature (2004) 2.05
How does radiation damage in protein crystals depend on X-ray dose? Structure (2003) 2.01
Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. EMBO J (2004) 2.01
Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1. Mol Cell (2002) 2.00
Ifitm3 limits the severity of acute influenza in mice. PLoS Pathog (2012) 1.97
Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching. Nature (2011) 1.93
Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions. J Virol (2006) 1.91
Recognition of the centromere-specific histone Cse4 by the chaperone Scm3. Proc Natl Acad Sci U S A (2011) 1.87
The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry. Cell Host Microbe (2013) 1.86
Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion. Proc Natl Acad Sci U S A (2006) 1.83
Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor. J Biol Chem (2002) 1.82
Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature (2004) 1.81
Atomic model of an infectious rotavirus particle. EMBO J (2010) 1.79
Influenza A virus neuraminidase limits viral superinfection. J Virol (2008) 1.79
Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain. Structure (2006) 1.76
Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin. Proc Natl Acad Sci U S A (2002) 1.75
Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch. J Biol Chem (2007) 1.72
Sulphated tyrosines mediate association of chemokines and Plasmodium vivax Duffy binding protein with the Duffy antigen/receptor for chemokines (DARC). Mol Microbiol (2005) 1.71
Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc Natl Acad Sci U S A (2012) 1.70
Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine. Biochem Biophys Res Commun (2004) 1.67
The role of post-translational modifications of the CXCR4 amino terminus in stromal-derived factor 1 alpha association and HIV-1 entry. J Biol Chem (2002) 1.66
Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab. Science (2009) 1.66
X-ray crystal structure of the rotavirus inner capsid particle at 3.8 A resolution. J Mol Biol (2010) 1.61
Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction. J Mol Biol (2007) 1.60
Stu2p binds tubulin and undergoes an open-to-closed conformational change. J Cell Biol (2006) 1.57
Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding. Structure (2007) 1.54
Evaluation of human monoclonal antibody 80R for immunoprophylaxis of severe acute respiratory syndrome by an animal study, epitope mapping, and analysis of spike variants. J Virol (2005) 1.54
Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R. J Biol Chem (2006) 1.53
Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolution. Structure (2005) 1.53
TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog (2013) 1.53
Mapping binding residues in the Plasmodium vivax domain that binds Duffy antigen during red cell invasion. Mol Microbiol (2005) 1.52
The active conformation of the PAK1 kinase domain. Structure (2005) 1.50
The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments. Cell (2010) 1.48
Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell (2003) 1.48