Published in Biochim Biophys Acta on October 25, 2007
Physiology and function of the tight junction. Cold Spring Harb Perspect Biol (2009) 3.06
Intestinal barrier function: molecular regulation and disease pathogenesis. J Allergy Clin Immunol (2009) 2.63
Cytokine regulation of tight junctions. Biochim Biophys Acta (2008) 2.16
Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin. BMC Biol (2009) 2.07
Claudins and the modulation of tight junction permeability. Physiol Rev (2013) 2.05
The claudins. Genome Biol (2009) 1.76
The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation. Proc Natl Acad Sci U S A (2009) 1.73
Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density. Nat Genet (2009) 1.73
Claudin association with CD81 defines hepatitis C virus entry. J Biol Chem (2010) 1.67
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. J Virol (2008) 1.62
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Cell (2016) 1.57
Claudin family of proteins and cancer: an overview. J Oncol (2010) 1.42
Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function. Am J Pathol (2011) 1.38
Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family. BMC Cell Biol (2009) 1.32
A claudin-9-based ion permeability barrier is essential for hearing. PLoS Genet (2009) 1.29
Vulnerability of polarised intestinal porcine epithelial cells to mycotoxin deoxynivalenol depends on the route of application. PLoS One (2011) 1.24
Residues in a highly conserved claudin-1 motif are required for hepatitis C virus entry and mediate the formation of cell-cell contacts. J Virol (2009) 1.19
Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion. Proc Natl Acad Sci U S A (2010) 1.17
Differential effects of claudin-3 and claudin-4 on alveolar epithelial barrier function. Am J Physiol Lung Cell Mol Physiol (2011) 1.17
Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease. Lung Cancer (2008) 1.17
Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis. Acta Neuropathol (2011) 1.16
Tight junctions in the testis: new perspectives. Philos Trans R Soc Lond B Biol Sci (2010) 1.16
Genetics of osteoporosis: accelerating pace in gene identification and validation. Hum Genet (2009) 1.14
Modulation of tight junction structure and function by kinases and phosphatases targeting occludin. J Biomed Biotechnol (2012) 1.12
Molecular determinants of the interaction between Clostridium perfringens enterotoxin fragments and claudin-3. J Biol Chem (2009) 1.11
Claudins and the kidney. Annu Rev Physiol (2012) 1.11
Differential expression of claudin tight junction proteins in the human cortical nephron. Nephrol Dial Transplant (2010) 1.11
The claudin family of proteins in human malignancy: a clinical perspective. Cancer Manag Res (2013) 1.10
Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia. J Neurochem (2008) 1.07
Tight junctions in lung cancer and lung metastasis: a review. Int J Clin Exp Pathol (2012) 1.05
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nat Struct Mol Biol (2013) 1.05
Emerging roles of claudins in human cancer. Int J Mol Sci (2013) 1.05
Claudins in lung diseases. Respir Res (2011) 1.05
Claudin and occludin expression and function in the seminiferous epithelium. Philos Trans R Soc Lond B Biol Sci (2010) 1.01
Tight junctions: a barrier to the initiation and progression of breast cancer? J Biomed Biotechnol (2009) 1.01
Hepatitis C Virus entry: the early steps in the viral replication cycle. Virol J (2009) 1.01
Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier. Histochem Cell Biol (2012) 1.00
Claudins: control of barrier function and regulation in response to oxidant stress. Antioxid Redox Signal (2011) 1.00
Differential pathways of claudin oligomerization and integration into tight junctions. Tissue Barriers (2013) 0.99
Intracellular transport of Toxoplasma gondii through the blood-brain barrier. J Neuroimmunol (2010) 0.98
Inflammatory mediators weaken the amniotic membrane barrier through disruption of tight junctions. J Physiol (2010) 0.98
The PIKfyve inhibitor YM201636 blocks the continuous recycling of the tight junction proteins claudin-1 and claudin-2 in MDCK cells. PLoS One (2012) 0.97
Claudin 5 expression in mouse seminiferous epithelium is dependent upon the transcription factor ets variant 5 and contributes to blood-testis barrier function. Biol Reprod (2009) 0.96
The level of claudin-7 is reduced as an early event in colorectal carcinogenesis. BMC Cancer (2011) 0.96
Claudins: Gatekeepers of lung epithelial function. Semin Cell Dev Biol (2015) 0.94
Visualization and quantitative analysis of reconstituted tight junctions using localization microscopy. PLoS One (2012) 0.94
Intestinal phosphate transport. Adv Chronic Kidney Dis (2011) 0.94
New aspects of the molecular constituents of tissue barriers. J Neural Transm (Vienna) (2010) 0.93
The kidney tight junction (Review). Int J Mol Med (2014) 0.92
Roles for claudins in alveolar epithelial barrier function. Ann N Y Acad Sci (2012) 0.92
Age-related changes of claudin expression in mouse liver, kidney, and pancreas. J Gerontol A Biol Sci Med Sci (2009) 0.92
Mechanism of Clostridium perfringens enterotoxin interaction with claudin-3/-4 protein suggests structural modifications of the toxin to target specific claudins. J Biol Chem (2011) 0.92
Human claudin-8 and -14 are receptors capable of conveying the cytotoxic effects of Clostridium perfringens enterotoxin. MBio (2013) 0.92
Reciprocal influence of connexins and apical junction proteins on their expressions and functions. Biochim Biophys Acta (2008) 0.91
Protein kinase C activation has distinct effects on the localization, phosphorylation and detergent solubility of the claudin protein family in tight and leaky epithelial cells. J Membr Biol (2010) 0.91
Role of Estrogen Receptor-α in the Regulation of Claudin-6 Expression in Breast Cancer Cells. J Breast Cancer (2011) 0.91
Activation of AMP-activated protein kinase alleviates high-glucose-induced dysfunction of brain microvascular endothelial cell tight-junction dynamics. Free Radic Biol Med (2012) 0.91
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use. J Cereb Blood Flow Metab (2016) 0.90
Effects of aging on blood brain barrier and matrix metalloproteases following controlled cortical impact in mice. Exp Neurol (2011) 0.90
Transcription factor AP-2γ is a core regulator of tight junction biogenesis and cavity formation during mouse early embryogenesis. Development (2012) 0.90
On the interaction of Clostridium perfringens enterotoxin with claudins. Toxins (Basel) (2010) 0.90
Strain-dependent augmentation of tight-junction barrier function in human primary epidermal keratinocytes by Lactobacillus and Bifidobacterium lysates. Appl Environ Microbiol (2013) 0.90
Claudins overexpression in ovarian cancer: potential targets for Clostridium Perfringens Enterotoxin (CPE) based diagnosis and therapy. Int J Mol Sci (2013) 0.89
Transcriptional profiling of human cavernosal endothelial cells reveals distinctive cell adhesion phenotype and role for claudin 11 in vascular barrier function. Physiol Genomics (2009) 0.88
Loss of tight junction proteins (Claudin 1, 4, and 7) correlates with aggressive behavior in colorectal carcinoma. Med Sci Monit (2014) 0.88
Apical acidity decreases inhibitory effect of omeprazole on Mg(2+) absorption and claudin-7 and -12 expression in Caco-2 monolayers. Exp Mol Med (2012) 0.87
Epithelial cell polarity and tumorigenesis: new perspectives for cancer detection and treatment. Acta Pharmacol Sin (2011) 0.87
Breaking barriers. New insights into airway epithelial barrier function in health and disease. Am J Respir Cell Mol Biol (2014) 0.87
Paracellular tightness and claudin-5 expression is increased in the BCEC/astrocyte blood-brain barrier model by increasing media buffer capacity during growth. AAPS J (2010) 0.87
Claudins reign: The claudin/EMP/PMP22/γ channel protein family in C. elegans. Tissue Barriers (2013) 0.87
Triggers and effectors of oxidative stress at blood-brain barrier level: relevance for brain ageing and neurodegeneration. Oxid Med Cell Longev (2013) 0.87
Claudin-3 and claudin-5 protein folding and assembly into the tight junction are controlled by non-conserved residues in the transmembrane 3 (TM3) and extracellular loop 2 (ECL2) segments. J Biol Chem (2014) 0.86
Pathways and progress in improving drug delivery through the intestinal mucosa and blood-brain barriers. Ther Deliv (2014) 0.86
Nitric oxide and airway epithelial barrier function: regulation of tight junction proteins and epithelial permeability. Arch Biochem Biophys (2008) 0.86
Clinicopathological significance of claudin-4 in gastric carcinoma. World J Surg Oncol (2013) 0.86
Gastrointestinal mucosal barrier function and diseases. J Gastroenterol (2016) 0.85
Redox-sensitive structure and function of the first extracellular loop of the cell-cell contact protein claudin-1: lessons from molecular structure to animals. Antioxid Redox Signal (2015) 0.85
Claudins in teleost fishes. Tissue Barriers (2013) 0.85
Claudin-20 promotes an aggressive phenotype in human breast cancer cells. Tissue Barriers (2013) 0.85
Regulation of claudins in blood-tissue barriers under physiological and pathological states. Tissue Barriers (2013) 0.84
Lecture: New light on the role of claudins in the kidney. Organogenesis (2012) 0.84
Mosaic expression of claudins in thick ascending limbs of Henle results in spatial separation of paracellular Na+ and Mg2+ transport. Proc Natl Acad Sci U S A (2016) 0.84
Myofibroblast keratinocyte growth factor reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells. Growth Factors (2012) 0.83
Freeze-fracture electron microscopic study of tight junction strands in HEK293 cells and MDCK II cells expressing claudin-1 mutants in the second extracellular loop. Histochem Cell Biol (2009) 0.83
Dissecting gene expression at the blood-brain barrier. Front Neurosci (2014) 0.83
Tight junction proteins and oxidative stress in heavy metals-induced nephrotoxicity. Biomed Res Int (2013) 0.82
The expression patterns of tight junction protein claudin-1, -3, and -4 in human gastric neoplasms and adjacent non-neoplastic tissues. Int J Clin Exp Pathol (2015) 0.81
Overexpression of Claudin-1 is Associated with Advanced Clinical Stage and Invasive Pathologic Characteristics of Oral Squamous Cell Carcinoma. Head Neck Pathol (2014) 0.81
Junctional adhesion molecule A promotes epithelial tight junction assembly to augment lung barrier function. Am J Pathol (2014) 0.81
Gene expression analysis in SV-40 immortalized human corneal epithelial cells cultured with an air-liquid interface. Mol Vis (2010) 0.81
Hepatic tight junctions: from viral entry to cancer metastasis. World J Gastroenterol (2010) 0.81
Clostridium perfringens Enterotoxin: Action, Genetics, and Translational Applications. Toxins (Basel) (2016) 0.80
Slug is associated with poor survival in squamous cell carcinoma of the lung. Int J Clin Exp Pathol (2014) 0.80
Goblet cells of the conjunctiva: A review of recent findings. Prog Retin Eye Res (2016) 0.80
Junctional proteins of the blood-brain barrier: New insights into function and dysfunction. Tissue Barriers (2016) 0.80
Current trends in salivary gland tight junctions. Tissue Barriers (2016) 0.79
Apoptosis screening of human chromosome 21 proteins reveals novel cell death regulators. Mol Biol Rep (2009) 0.79
Claudins 10 and 18 are predominantly expressed in lung adenocarcinomas and in tumors of nonsmokers. Int J Clin Exp Pathol (2011) 0.79
Formation of tight junction: determinants of homophilic interaction between classic claudins. FASEB J (2007) 2.43
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling. FASEB J (2007) 1.63
The tight junction protein occludin and the adherens junction protein alpha-catenin share a common interaction mechanism with ZO-1. J Biol Chem (2004) 1.42
Serum markers support disease-specific glial pathology in major depression. J Affect Disord (2008) 1.18
Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion. Proc Natl Acad Sci U S A (2010) 1.17
Elucidating the principles of the molecular organization of heteropolymeric tight junction strands. Cell Mol Life Sci (2011) 1.12
Analysis of RovA, a transcriptional regulator of Yersinia pseudotuberculosis virulence that acts through antirepression and direct transcriptional activation. J Biol Chem (2005) 1.12
Molecular determinants of the interaction between Clostridium perfringens enterotoxin fragments and claudin-3. J Biol Chem (2009) 1.11
Participation of the second extracellular loop of claudin-5 in paracellular tightening against ions, small and large molecules. Cell Mol Life Sci (2010) 1.07
In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization. J Cell Sci (2012) 1.06
Occludin protein family: oxidative stress and reducing conditions. Antioxid Redox Signal (2011) 1.04
Differential protein expression in brain capillary endothelial cells induced by hypoxia and posthypoxic reoxygenation. Proteomics (2006) 1.04
S100B is increased in mood disorders and may be reduced by antidepressive treatment. Neuroreport (2002) 0.99
Neuron-specific enolase is unaltered whereas S100B is elevated in serum of patients with schizophrenia--original research and meta-analysis. Psychiatry Res (2009) 0.99
Structure and function of extracellular claudin domains. Ann N Y Acad Sci (2009) 0.97
Transient opening of the perineurial barrier for analgesic drug delivery. Proc Natl Acad Sci U S A (2012) 0.95
Assembly of tight junction is regulated by the antagonism of conventional and novel protein kinase C isoforms. Int J Biochem Cell Biol (2005) 0.95
Serum S100B is increased during early treatment with antipsychotics and in deficit schizophrenia. Schizophr Res (2003) 0.95
Visualization and quantitative analysis of reconstituted tight junctions using localization microscopy. PLoS One (2012) 0.94
Protein markers of ischemic insult in brain endothelial cells identified using 2D gel electrophoresis and ICAT-based quantitative proteomics. J Proteome Res (2007) 0.94
Mood disorders are glial disorders: evidence from in vivo studies. Cardiovasc Psychiatry Neurol (2010) 0.93
Redox-sensitivity of the dimerization of occludin. Cell Mol Life Sci (2009) 0.93
The oligomerization of the coiled coil-domain of occludin is redox sensitive. Ann N Y Acad Sci (2009) 0.93
Mechanism of Clostridium perfringens enterotoxin interaction with claudin-3/-4 protein suggests structural modifications of the toxin to target specific claudins. J Biol Chem (2011) 0.92
Evidence that N-acetylcysteine inhibits TNF-alpha-induced cerebrovascular endothelin-1 upregulation via inhibition of mitogen- and stress-activated protein kinase. Free Radic Biol Med (2006) 0.90
On the interaction of Clostridium perfringens enterotoxin with claudins. Toxins (Basel) (2010) 0.90
Evaluation of the titanium dioxide approach for MS analysis of phosphopeptides. J Mass Spectrom (2006) 0.89
Protective effects of peroxiredoxin-1 at the injured blood-brain barrier. Free Radic Biol Med (2008) 0.87
CK2-dependent phosphorylation of occludin regulates the interaction with ZO-proteins and tight junction integrity. Cell Commun Signal (2013) 0.86
Claudin-3 and claudin-5 protein folding and assembly into the tight junction are controlled by non-conserved residues in the transmembrane 3 (TM3) and extracellular loop 2 (ECL2) segments. J Biol Chem (2014) 0.86
A peptidomimetic tight junction modulator to improve regional analgesia. Mol Pharm (2012) 0.84
Tricellulin forms homomeric and heteromeric tight junctional complexes. Cell Mol Life Sci (2010) 0.83
Protein delivery of caspase-3 induces cell death in malignant C6 glioma, primary astrocytes and immortalized and primary brain capillary endothelial cells. J Neurooncol (2005) 0.82
The hinge region of the scaffolding protein of cell contacts, zonula occludens protein 1, regulates interacting with various signaling proteins. J Cell Biochem (2012) 0.81
Tight junctions and tissue barriers. Antioxid Redox Signal (2011) 0.80
Claudin-derived peptides are internalized via specific endocytosis pathways. Ann N Y Acad Sci (2012) 0.79
Calcium/calmodulin-dependent protein kinase IIdelta 2 and gamma isoforms regulate potassium currents of rat brain capillary endothelial cells under hypoxic conditions. J Biol Chem (2002) 0.78
Involvement of claudins in zebrafish brain ventricle morphogenesis. Ann N Y Acad Sci (2012) 0.78
A strategy for enrichment of claudins based on their affinity to Clostridium perfringens enterotoxin. BMC Mol Biol (2009) 0.78
Functional and structural characterization of anti-beta1-adrenoceptor autoantibodies of spontaneously hypertensive rats. Mol Cell Biochem (2003) 0.78
Association between segments of zonula occludens proteins: live-cell FRET and mass spectrometric analysis. Ann N Y Acad Sci (2012) 0.77
Highly conserved cysteines are involved in the oligomerization of occludin-redox dependency of the second extracellular loop. Antioxid Redox Signal (2013) 0.77
Disturbed function of the blood-cerebrospinal fluid barrier aggravates neuro-inflammation. Acta Neuropathol (2013) 0.77
Determinants contributing to claudin ion channel formation. Ann N Y Acad Sci (2012) 0.76
Release patterns of astrocytic and neuronal biochemical markers in serum during and after experimental settings of cardiac surgery. Restor Neurol Neurosci (2003) 0.75
Proteomics of brain endothelium. Separation of proteins by two-dimensional gel electrophoresis and identification by mass spectrometry. Methods Mol Med (2003) 0.75