Published in J Mol Biol on November 01, 2007
Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC. Nat Struct Mol Biol (2011) 1.48
Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence. Proc Natl Acad Sci U S A (2009) 1.13
De novo assembly of a field isolate genome reveals novel Plasmodium vivax erythrocyte invasion genes. PLoS Negl Trop Dis (2013) 1.07
Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii. Proc Natl Acad Sci U S A (2011) 1.03
Malaria adhesins: structure and function. Cell Microbiol (2014) 0.89
The apicomplexan glideosome and adhesins - Structures and function. J Struct Biol (2015) 0.84
Critical glycosylated residues in exon three of erythrocyte glycophorin A engage Plasmodium falciparum EBA-175 and define receptor specificity. MBio (2014) 0.84
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell (2005) 8.39
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science (2011) 7.86
Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. Nature (2006) 7.56
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell (2003) 7.04
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature (2006) 6.00
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. Nature (2011) 5.28
Structure of mammalian AMPK and its regulation by ADP. Nature (2011) 4.27
Structure and catalytic mechanism of the human histone methyltransferase SET7/9. Nature (2003) 4.00
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature (2008) 3.79
Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes. Cell (2007) 3.37
A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes. Science (2010) 3.27
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nat Struct Mol Biol (2004) 3.26
Structural basis for AMP binding to mammalian AMP-activated protein kinase. Nature (2007) 3.26
A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites. J Biol Chem (2003) 2.84
High-resolution structure of a retroviral capsid hexameric amino-terminal domain. Nature (2004) 2.84
High-level expression of the malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion. Infect Immun (2002) 2.61
How insulin engages its primary binding site on the insulin receptor. Nature (2013) 2.52
Specificity and mechanism of the histone methyltransferase Pr-Set7. Genes Dev (2005) 2.50
Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms. Semin Cancer Biol (2006) 2.42
Crystal structure of the malaria vaccine candidate apical membrane antigen 1. Science (2005) 2.39
Receptor binding by an H7N9 influenza virus from humans. Nature (2013) 2.33
Molecular basis of phosphorylation-induced activation of the NADPH oxidase. Cell (2003) 2.31
Crystal structure and functional analysis of the histone methyltransferase SET7/9. Cell (2002) 2.27
Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin. Proc Natl Acad Sci U S A (2012) 2.18
A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage. Cell (2009) 2.07
Key features of the interaction between Pcf11 CID and RNA polymerase II CTD. Nat Struct Mol Biol (2005) 2.07
Molecular identification of a malaria merozoite surface sheddase. PLoS Pathog (2005) 2.06
Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2. Mol Cell (2002) 1.99
Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957. Proc Natl Acad Sci U S A (2009) 1.98
A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint. PLoS Biol (2010) 1.90
A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage. J Biol Chem (2003) 1.88
Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode. Science (2010) 1.86
Robust inducible Cre recombinase activity in the human malaria parasite Plasmodium falciparum enables efficient gene deletion within a single asexual erythrocytic growth cycle. Mol Microbiol (2013) 1.85
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite. J Cell Biol (2006) 1.84
An inhibitory antibody blocks interactions between components of the malarial invasion machinery. PLoS Pathog (2009) 1.81
Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development. J Cell Sci (2003) 1.78
Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis. Science (2008) 1.74
A multifunctional serine protease primes the malaria parasite for red blood cell invasion. EMBO J (2009) 1.67
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal (2011) 1.62
Structural comparison of apical membrane antigen 1 orthologues and paralogues in apicomplexan parasites. Mol Biochem Parasitol (2005) 1.51
Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1. J Biol Chem (2006) 1.47
Structure and regulation of the human Nek2 centrosomal kinase. J Biol Chem (2006) 1.45
Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens. Mol Microbiol (2005) 1.45
Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex. Mol Cell Proteomics (2004) 1.44
Receptor binding by a ferret-transmissible H5 avian influenza virus. Nature (2013) 1.43
In vitro regulation of budding yeast Bfa1/Bub2 GAP activity by Cdc5. J Biol Chem (2003) 1.40
A new release on life: emerging concepts in proteolysis and parasite invasion. Mol Microbiol (2005) 1.38
Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair. Mol Cell (2012) 1.37
ADP regulates SNF1, the Saccharomyces cerevisiae homolog of AMP-activated protein kinase. Cell Metab (2011) 1.37
Prion and water: tight and dynamical hydration sites have a key role in structural stability. Proc Natl Acad Sci U S A (2005) 1.30
The use of in vitro peptide-library screens in the analysis of phosphoserine/threonine-binding domain structure and function. Annu Rev Biophys Biomol Struct (2004) 1.28
MgF(3)(-) as a transition state analog of phosphoryl transfer. Chem Biol (2002) 1.25
Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes. Proc Natl Acad Sci U S A (2012) 1.24
Atomic resolution insight into host cell recognition by Toxoplasma gondii. EMBO J (2007) 1.22
TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase. Mol Microbiol (2003) 1.19
Clb6/Cdc28 and Cdc14 regulate phosphorylation status and cellular localization of Swi6. Mol Cell Biol (2004) 1.18
The role of malaria merozoite proteases in red blood cell invasion. Curr Opin Microbiol (2005) 1.17
Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation. J Mol Biol (2007) 1.17
Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress. PLoS Pathog (2013) 1.16
Global identification of multiple substrates for Plasmodium falciparum SUB1, an essential malarial processing protease. Infect Immun (2011) 1.15
Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS. J Mol Biol (2010) 1.15
Structure of the complex of calmodulin with the target sequence of calmodulin-dependent protein kinase I: studies of the kinase activation mechanism. Biochemistry (2002) 1.14
Function of the nucleotide exchange activity of vav1 in T cell development and activation. Sci Signal (2009) 1.13
Structural and functional analysis of phosphothreonine-dependent FHA domain interactions. Structure (2010) 1.13
H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis. PLoS Pathog (2012) 1.13
An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis. Sci Signal (2009) 1.12
Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors. Biochemistry (2006) 1.12
Rna14-Rna15 assembly mediates the RNA-binding capability of Saccharomyces cerevisiae cleavage factor IA. Nucleic Acids Res (2004) 1.11
Structural and functional analysis of prehistoric lentiviruses uncovers an ancient molecular interface. Cell Host Microbe (2010) 1.11
Functional analysis of the human papillomavirus type 16 E1=E4 protein provides a mechanism for in vivo and in vitro keratin filament reorganization. J Virol (2004) 1.10
Subtilisin-like proteases of the malaria parasite. Mol Microbiol (2004) 1.10
Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling. J Biol Chem (2002) 1.07