Published in PLoS One on November 28, 2007
The glial nature of embryonic and adult neural stem cells. Annu Rev Neurosci (2009) 8.38
Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol (2009) 5.83
Notch-dependent differentiation of adult airway basal stem cells. Cell Stem Cell (2011) 2.95
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity (2011) 2.59
The many facets of Notch ligands. Oncogene (2008) 2.57
Parent stem cells can serve as niches for their daughter cells. Nature (2015) 1.64
Canonical and non-canonical Notch ligands. Curr Top Dev Biol (2010) 1.62
Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations. Cell Stem Cell (2015) 1.61
Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol (2010) 1.51
Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat Med (2013) 1.49
Sex hormones establish a reserve pool of adult muscle stem cells. Nat Cell Biol (2016) 1.39
Signalling pathways that control vertebrate haematopoietic stem cell specification. Nat Rev Immunol (2013) 1.21
Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice. J Clin Invest (2009) 1.12
Notch ligand ubiquitylation: what is it good for? Dev Cell (2011) 1.09
Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches. Mol Cell Biol (2008) 1.07
Notch: architect, landscaper, and guardian of the intestine. Gastroenterology (2011) 1.03
Mind bomb 1 is required for pancreatic β-cell formation. Proc Natl Acad Sci U S A (2012) 1.02
Notch signalling in context. Nat Rev Mol Cell Biol (2016) 0.99
Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development. J Exp Med (2008) 0.98
Conditional Cre/LoxP strategies for the study of hematopoietic stem cell formation. Blood Cells Mol Dis (2009) 0.97
The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation. J Clin Invest (2013) 0.96
NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses. PLoS One (2012) 0.96
Regulation of epithelial polarity by the E3 ubiquitin ligase Neuralized and the Bearded inhibitors in Drosophila. Nat Cell Biol (2012) 0.94
Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized. J Cell Biol (2011) 0.93
Ubiquitinations in the notch signaling pathway. Int J Mol Sci (2013) 0.86
The E3 ligase Mind bomb-1 (Mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord. J Biol Chem (2012) 0.86
Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol (2015) 0.85
Essential genes for astroglial development and axon pathfinding during zebrafish embryogenesis. Dev Dyn (2010) 0.85
Mind bomb-1 is an essential modulator of long-term memory and synaptic plasticity via the Notch signaling pathway. Mol Brain (2012) 0.85
Lysine 63-linked TANK-binding kinase 1 ubiquitination by mindbomb E3 ubiquitin protein ligase 2 is mediated by the mitochondrial antiviral signaling protein. J Virol (2014) 0.83
Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation. PLoS One (2012) 0.82
Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development. BMC Dev Biol (2010) 0.81
RAD-QTL Mapping Reveals Both Genome-Level Parallelism and Different Genetic Architecture Underlying the Evolution of Body Shape in Lake Whitefish (Coregonus clupeaformis) Species Pairs. G3 (Bethesda) (2015) 0.80
Juxtacrine signaling is inherently noisy. Biophys J (2014) 0.80
Notch signaling in the malignant bone marrow microenvironment: implications for a niche-based model of oncogenesis. Ann N Y Acad Sci (2014) 0.80
Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth. Mol Cell Proteomics (2015) 0.80
S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development. Mol Cell Biol (2014) 0.79
FIH-1, a novel interactor of mindbomb, functions as an essential anti-angiogenic factor during zebrafish vascular development. PLoS One (2014) 0.79
Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis. Elife (2016) 0.78
A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases. Mol Cell (2015) 0.77
Mind Bomb-2 Regulates Hippocampus-dependent Memory Formation and Synaptic Plasticity. Korean J Physiol Pharmacol (2015) 0.77
Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish. Biol Open (2015) 0.77
Structure and function of the Mind bomb E3 ligase in the context of Notch signal transduction. Curr Opin Struct Biol (2016) 0.77
Mind Bomb-Binding Partner RanBP9 Plays a Contributory Role in Retinal Development. Mol Cells (2017) 0.75
Identification of the essential protein domains for Mib2 function during the development of the Drosophila larval musculature and adult flight muscles. PLoS One (2017) 0.75
The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila. Mol Cell Neurosci (2015) 0.75
Notch signaling: cell fate control and signal integration in development. Science (1999) 28.83
hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo. Genesis (2001) 6.29
Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow. J Exp Med (2001) 5.97
Notch signaling: control of cell communication and cell fate. Development (2004) 5.95
Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev (1999) 4.75
Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev Cell (2003) 4.30
Dosage-sensitive requirement for mouse Dll4 in artery development. Genes Dev (2004) 4.14
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. Proc Natl Acad Sci U S A (2004) 4.06
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev (2004) 3.95
Regulation of notch signaling activity. Curr Biol (2004) 3.88
Requirement for BMP signaling in interdigital apoptosis and scale formation. Science (1996) 3.40
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development (2000) 2.94
Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev (1998) 2.70
gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell (2004) 2.68
Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat Immunol (2004) 2.63
Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development. Nat Genet (2000) 2.59
Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta. Dev Cell (2001) 2.35
neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis. Dev Cell (2001) 2.22
Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development (2005) 2.06
Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development (2006) 2.06
The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands. J Cell Biol (2005) 1.88
Notch1 is required for neuronal and glial differentiation in the cerebellum. Development (2002) 1.69
Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling. Dev Cell (2001) 1.65
Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development. Development (1997) 1.56
The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development (2005) 1.55
Protein degradation: four E3s for the notch pathway. Curr Biol (2002) 1.55
The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons. EMBO J (1991) 1.53
Interchangeability of Caenorhabditis elegans DSL proteins and intrinsic signalling activity of their extracellular domains in vivo. Development (1995) 1.52
Notch/RBP-J signaling regulates epidermis/hair fate determination of hair follicular stem cells. Curr Biol (2003) 1.46
The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands. Development (1996) 1.46
Characterization of the neuronal marker NeuN as a multiply phosphorylated antigen with discrete subcellular localization. J Neurosci Res (2005) 1.45
Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila. PLoS Biol (2005) 1.43
Serrate2 is disrupted in the mouse limb-development mutant syndactylism. Nature (1997) 1.40
Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. Development (1997) 1.37
The interplay between DSL proteins and ubiquitin ligases in Notch signaling. Development (2005) 1.28
Mind bomb-2 is an E3 ligase for Notch ligand. J Biol Chem (2005) 1.27
Neuralized functions as an E3 ubiquitin ligase during Drosophila development. Curr Biol (2001) 1.24
Restricted expression of the hyaluronan receptor, CD44, during postimplantation mouse embryogenesis suggests key roles in tissue formation and patterning. Development (1993) 1.20
Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis. Dev Biol (2005) 1.13
Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech Dev (2005) 1.11
The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly. Dev Biol (2007) 1.05
Jagged1 ablation results in cerebellar granule cell migration defects and depletion of Bergmann glia. Dev Neurosci (2006) 1.04
Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized. Proc Natl Acad Sci U S A (2001) 1.02
Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1. J Biol Chem (2006) 0.97
Isolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary gland. Mol Cell Biol (2001) 0.91
The NHR1 domain of Neuralized binds Delta and mediates Delta trafficking and Notch signaling. Mol Biol Cell (2006) 0.91
Murine numb regulates granule cell maturation in the cerebellum. Dev Biol (2004) 0.82
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell (2008) 7.79
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell (2009) 5.99
Regulation of cancer cell migration and bone metastasis by RANKL. Nature (2006) 5.27
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging. Nat Genet (2004) 4.77
Tiling of the Drosophila epidermis by multidendritic sensory neurons. Development (2002) 4.59
Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev Cell (2003) 4.30
Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall. Nature (2010) 3.13
Notch-dependent differentiation of adult airway basal stem cells. Cell Stem Cell (2011) 2.95
Local generation of glia is a major astrocyte source in postnatal cortex. Nature (2012) 2.87
Dendrites of distinct classes of Drosophila sensory neurons show different capacities for homotypic repulsion. Curr Biol (2003) 2.81
Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons. Cell (2003) 2.80
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis. Nature (2002) 2.74
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity (2011) 2.59
Mechanisms that regulate establishment, maintenance, and remodeling of dendritic fields. Annu Rev Neurosci (2007) 2.59
Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts. Development (2002) 2.54
Growing dendrites and axons differ in their reliance on the secretory pathway. Cell (2007) 2.51
Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev (2006) 2.49
Probing protein electrostatics with a synthetic fluorescent amino acid. Science (2002) 2.46
A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J (2008) 2.46
The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron (2010) 2.44
Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nat Cell Biol (2008) 2.33
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron (2006) 2.31
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases. Genome Res (2013) 2.28
TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell (2012) 2.24
The phox homology domain of phospholipase D activates dynamin GTPase activity and accelerates EGFR endocytosis. Nat Cell Biol (2006) 2.23
Asymmetric cell division. Curr Opin Cell Biol (2004) 2.22
Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. Science (2006) 2.16
Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases. Proc Natl Acad Sci U S A (2006) 2.16
Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain. J Biol Chem (2003) 2.14
Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae. Proc Natl Acad Sci U S A (2007) 2.14
Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. Neuron (2012) 2.13
Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs. Cell (2012) 2.09
Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature (2012) 2.07
Mind bomb 1 is essential for generating functional Notch ligands to activate Notch. Development (2005) 2.06
The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. Genes Dev (2006) 2.06
Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Curr Biol (2004) 2.05
Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor. Mol Pharmacol (2006) 2.00
Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling. Proc Natl Acad Sci U S A (2005) 1.96
Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells. Neuron (2008) 1.89
Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice. Curr Biol (2002) 1.85
Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains. Proc Natl Acad Sci U S A (2006) 1.84
Drosophila neuroblast asymmetric cell division: recent advances and implications for stem cell biology. Neuron (2006) 1.83
A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels. Science (2003) 1.76
Characteristics of Asian dust transport based on synoptic meteorological analysis over Korea. J Air Waste Manag Assoc (2006) 1.74
Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron (2003) 1.73
Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE. Nature (2002) 1.71
Structural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C beta-lactamase. Mol Microbiol (2006) 1.70
ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C. Neuron (2003) 1.70
Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron (2002) 1.69
The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron (2009) 1.68
Receptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2. Mol Cell Biol (2006) 1.67
Identification of a compound that directly stimulates phospholipase C activity. Mol Pharmacol (2003) 1.67
Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies. Am J Hum Genet (2012) 1.64
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev (2012) 1.64
Activity of the mitochondrial calcium uniporter varies greatly between tissues. Nat Commun (2012) 1.64
A quantitative assessment of models for voltage-dependent gating of ion channels. Proc Natl Acad Sci U S A (2004) 1.63
hamlet, a binary genetic switch between single- and multiple- dendrite neuron morphology. Science (2002) 1.61
Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. Mol Cell Biol (2009) 1.58
Structure prediction for the down state of a potassium channel voltage sensor. Nature (2006) 1.58
The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development (2005) 1.55
Impact of NAD(P)H:quinone oxidoreductase-1 on pigmentation. J Invest Dermatol (2009) 1.54
Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels. Proc Natl Acad Sci U S A (2008) 1.53
Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise. Proc Natl Acad Sci U S A (2012) 1.53
Escherichia coli enzyme IIANtr regulates the K+ transporter TrkA. Proc Natl Acad Sci U S A (2007) 1.52
Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism. Proc Natl Acad Sci U S A (2010) 1.51
Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron (2012) 1.50
WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome. Am J Hum Genet (2010) 1.49
O-GlcNAcase is essential for embryonic development and maintenance of genomic stability. Aging Cell (2012) 1.49
The coiled-coil protein shrub controls neuronal morphogenesis in Drosophila. Curr Biol (2006) 1.46
The polymorphism (-600 C>A) of CpG methylation site at the promoter region of CYP17A1 and its association of male infertility and testosterone levels. Gene (2013) 1.40
Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds. Pigment Cell Res (2007) 1.40
Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein. Neuron (2011) 1.38
The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron (2006) 1.37
NHERF2 specifically interacts with LPA2 receptor and defines the specificity and efficiency of receptor-mediated phospholipase C-beta3 activation. Mol Cell Biol (2004) 1.37
Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell (2005) 1.36
Dividing glial cells maintain differentiated properties including complex morphology and functional synapses. Proc Natl Acad Sci U S A (2008) 1.36
Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam. Genes Dev (2012) 1.33
Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity. Proc Natl Acad Sci U S A (2004) 1.32
Defective Notch activation in microenvironment leads to myeloproliferative disease. Blood (2008) 1.32
Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. J Mol Med (Berl) (2011) 1.32
Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways. Blood (2008) 1.30
Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane. Mol Biol Cell (2008) 1.30
Serum amyloid A binding to formyl peptide receptor-like 1 induces synovial hyperplasia and angiogenesis. J Immunol (2006) 1.30
Lethal giant larvae acts together with numb in notch inhibition and cell fate specification in the Drosophila adult sensory organ precursor lineage. Curr Biol (2003) 1.29
Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin. Proc Natl Acad Sci U S A (2010) 1.28
Mind bomb-2 is an E3 ligase for Notch ligand. J Biol Chem (2005) 1.27
The Drosophila myosin VI Jaguar is required for basal protein targeting and correct spindle orientation in mitotic neuroblasts. Dev Cell (2003) 1.26
Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb. Mol Cell Biol (2009) 1.25
Crystal structure of SEDL and its implications for a genetic disease spondyloepiphyseal dysplasia tarda. J Biol Chem (2002) 1.23
o-GlcNAc transferase is activated by CaMKIV-dependent phosphorylation under potassium chloride-induced depolarization in NG-108-15 cells. Cell Signal (2007) 1.23
Requirement of the dephospho-form of enzyme IIANtr for derepression of Escherichia coli K-12 ilvBN expression. Mol Microbiol (2005) 1.22