Published in Nature on October 31, 2002
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature (2010) 5.73
Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell (2011) 4.78
Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood (2010) 3.82
The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell (2009) 3.60
Tissue-specific stem cells: lessons from the skeletal muscle satellite cell. Cell Stem Cell (2012) 2.68
Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes Dev (2004) 2.55
Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron (2009) 2.23
Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell (2006) 2.06
Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation. Cell Stem Cell (2010) 1.86
Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J Neurosci (2005) 1.85
Eph/ephrin molecules--a hub for signaling and endocytosis. Genes Dev (2010) 1.64
Endocytosis and signaling: cell logistics shape the eukaryotic cell plan. Physiol Rev (2012) 1.61
Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system. Proc Natl Acad Sci U S A (2009) 1.60
Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis. Dev Cell (2011) 1.60
Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron (2011) 1.60
Signaling mechanisms regulating adult neural stem cells and neurogenesis. Biochim Biophys Acta (2012) 1.50
Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems. Development (2007) 1.47
High levels of Notch signaling down-regulate Numb and Numblike. J Cell Biol (2006) 1.47
Uncoupling dendrite growth and patterning: single-cell knockout analysis of NMDA receptor 2B. Neuron (2009) 1.45
Growth and folding of the mammalian cerebral cortex: from molecules to malformations. Nat Rev Neurosci (2014) 1.44
Neurogenesis at the brain-cerebrospinal fluid interface. Annu Rev Cell Dev Biol (2011) 1.42
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2. Mol Biol Cell (2006) 1.40
Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development. J Biol Chem (2009) 1.39
The cell fate determinant numb interacts with EHD/Rme-1 family proteins and has a role in endocytic recycling. Mol Biol Cell (2004) 1.34
Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors. Dev Biol (2007) 1.26
Visualizing the distribution of synapses from individual neurons in the mouse brain. PLoS One (2010) 1.26
Prox1 regulates the notch1-mediated inhibition of neurogenesis. PLoS Biol (2010) 1.23
The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron (2010) 1.22
NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis. Blood (2013) 1.21
Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1. Stem Cells (2012) 1.20
Notch, neural stem cells, and brain tumors. Cold Spring Harb Symp Quant Biol (2008) 1.19
Epicardial spindle orientation controls cell entry into the myocardium. Dev Cell (2010) 1.16
Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): an emerging signaling molecule. Prog Lipid Res (2010) 1.16
Presenilins are required for maintenance of neural stem cells in the developing brain. Mol Neurodegener (2008) 1.14
Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis. Development (2011) 1.13
Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development. Neural Dev (2008) 1.11
Neural stem cells in the developing and adult brains. J Cell Physiol (2009) 1.11
Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β. J Neurosci (2012) 1.08
The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis. J Neurosci (2009) 1.08
Intralineage directional Notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia. Neuron (2012) 1.08
Stem cell biology and neurodegenerative disease. Philos Trans R Soc Lond B Biol Sci (2004) 1.07
Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation. Mol Biol Cell (2012) 1.07
Extensions of MADM (mosaic analysis with double markers) in mice. PLoS One (2012) 1.06
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development (2011) 1.04
Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects. Sci Signal (2013) 1.04
VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels. Development (2011) 1.03
Arterial pole progenitors interpret opposing FGF/BMP signals to proliferate or differentiate. Development (2010) 1.02
Aging of the subventricular zone neural stem cell niche. Aging Dis (2011) 1.00
Two novel human NUMB isoforms provide a potential link between development and cancer. Neural Dev (2010) 1.00
MALS-3 regulates polarity and early neurogenesis in the developing cerebral cortex. Development (2008) 0.99
Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors. Elife (2014) 0.98
Primary cilia are required in a unique subpopulation of neural progenitors. Proc Natl Acad Sci U S A (2014) 0.98
Placental expression of estrogen receptor beta and its hormone binding variant--comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cells. Reprod Biol Endocrinol (2003) 0.96
Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway. Mol Cell Biol (2005) 0.94
Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev (2004) 0.93
Implications of hedgehog signaling antagonists for cancer therapy. Acta Biochim Biophys Sin (Shanghai) (2008) 0.92
Vascular endothelial growth factor receptor 3 controls neural stem cell activation in mice and humans. Cell Rep (2015) 0.92
A Nestin-cre transgenic mouse is insufficient for recombination in early embryonic neural progenitors. Biol Open (2012) 0.91
Regulation of lung cancer metastasis by Klf4-Numb-like signaling. Cancer Res (2013) 0.91
Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb. Mol Cell Proteomics (2012) 0.91
Neuroglobin and Alzheimer's dementia: genetic association and gene expression changes. Neurobiol Aging (2008) 0.91
Primary cilia and Gli3 activity regulate cerebral cortical size. Dev Neurobiol (2012) 0.90
Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development (2013) 0.87
Concise review: self-renewal in the central nervous system: neural stem cells from embryo to adult. Stem Cells Transl Med (2012) 0.86
Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain. Development (2014) 0.85
Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development. Blood (2015) 0.85
Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina. J Neurosci (2012) 0.85
Neocortical neurogenesis and neuronal migration. Wiley Interdiscip Rev Dev Biol (2012) 0.84
Numb-deficient satellite cells have regeneration and proliferation defects. Proc Natl Acad Sci U S A (2013) 0.83
Neurodevelopment. Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling. Science (2014) 0.83
Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development (2011) 0.83
Development of the embryonic and larval peripheral nervous system of Drosophila. Wiley Interdiscip Rev Dev Biol (2014) 0.81
Numb regulates acinar cell dedifferentiation and survival during pancreatic damage and acinar-to-ductal metaplasia. Gastroenterology (2013) 0.81
Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M. Oncotarget (2016) 0.81
Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels. Neuroscience (2009) 0.80
Numb family proteins: novel players in cardiac morphogenesis and cardiac progenitor cell differentiation. Biomol Concepts (2015) 0.80
Timing cell-fate determination during asymmetric cell divisions. Curr Opin Neurobiol (2008) 0.79
Mechanotransduction: tuning stem cells fate. J Funct Biomater (2011) 0.78
Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation. Mol Endocrinol (2010) 0.78
The expression changes of Numblike in rat brain cortex after traumatic brain injury. J Mol Histol (2012) 0.77
Golgi during development. Cold Spring Harb Perspect Biol (2011) 0.77
A Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4. Sci Rep (2015) 0.77
Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development. Cell Death Dis (2014) 0.77
Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor cilia. J Neurosci (2014) 0.76
Molecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cells. J Anal Sci Technol (2015) 0.76
Morphological and functional aspects of progenitors perturbed in cortical malformations. Front Cell Neurosci (2015) 0.76
NumbL is essential for Xenopus primary neurogenesis. BMC Dev Biol (2013) 0.76
Numb and Alzheimer's disease: the current picture. Front Neurosci (2012) 0.76
p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex. Biol Open (2014) 0.75
Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear. Front Cell Neurosci (2015) 0.75
Network analysis of microRNA and mRNA seasonal dynamics in a highly plastic sensorimotor neural circuit. BMC Genomics (2015) 0.75
Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development. PLoS One (2017) 0.75
Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy. Oncotarget (2016) 0.75
Novel Mechanisms of Spinal Cord Plasticity in a Mouse Model of Motoneuron Disease. Biomed Res Int (2015) 0.75
Neuroplasticity and Repair in Rodent Neurotoxic Models of Spinal Motoneuron Disease. Neural Plast (2016) 0.75
Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b. Cell Res (2016) 0.75
Phenotypic and genetic characterization of a patient with a de novo interstitial 14q24.1q24.3 deletion. Mol Cytogenet (2014) 0.75
Self-renewal of stem cells. Acta Naturae (2009) 0.75
Finding a niche for cardiac precursors. Elife (2014) 0.75
Numb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor and motor coordination. Proc Natl Acad Sci U S A (2015) 0.75
Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N Engl J Med (2009) 15.02
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell (2008) 7.79
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging. Nat Genet (2004) 4.77
Tiling of the Drosophila epidermis by multidendritic sensory neurons. Development (2002) 4.59
Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall. Nature (2010) 3.13
Local generation of glia is a major astrocyte source in postnatal cortex. Nature (2012) 2.87
Dendrites of distinct classes of Drosophila sensory neurons show different capacities for homotypic repulsion. Curr Biol (2003) 2.81
Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons. Cell (2003) 2.80
Major molecular differences between mammalian sexes are involved in drug metabolism and renal function. Dev Cell (2004) 2.65
Mechanisms that regulate establishment, maintenance, and remodeling of dendritic fields. Annu Rev Neurosci (2007) 2.59
Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts. Development (2002) 2.54
Growing dendrites and axons differ in their reliance on the secretory pathway. Cell (2007) 2.51
Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev (2006) 2.49
Probing protein electrostatics with a synthetic fluorescent amino acid. Science (2002) 2.46
The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron (2010) 2.44
Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons. Nat Cell Biol (2008) 2.33
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron (2006) 2.31
Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci (2004) 2.31
TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell (2012) 2.24
Asymmetric cell division. Curr Opin Cell Biol (2004) 2.22
Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. Science (2006) 2.16
Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae. Proc Natl Acad Sci U S A (2007) 2.14
Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. Neuron (2012) 2.13
Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature (2012) 2.07
The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. Genes Dev (2006) 2.06
Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma. Blood (2006) 2.06
Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Curr Biol (2004) 2.05
Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling. Proc Natl Acad Sci U S A (2005) 1.96
Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice. Curr Biol (2002) 1.85
Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains. Proc Natl Acad Sci U S A (2006) 1.84
Drosophila neuroblast asymmetric cell division: recent advances and implications for stem cell biology. Neuron (2006) 1.83
A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels. Science (2003) 1.76
Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron (2003) 1.73
ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C. Neuron (2003) 1.70
Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron (2002) 1.69
The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron (2009) 1.68
Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol (2005) 1.66
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev (2012) 1.64
Activity of the mitochondrial calcium uniporter varies greatly between tissues. Nat Commun (2012) 1.64
A quantitative assessment of models for voltage-dependent gating of ion channels. Proc Natl Acad Sci U S A (2004) 1.63
hamlet, a binary genetic switch between single- and multiple- dendrite neuron morphology. Science (2002) 1.61
Prior medical conditions and medication use and risk of non-Hodgkin lymphoma in Connecticut United States women. Cancer Causes Control (2004) 1.59
Structure prediction for the down state of a potassium channel voltage sensor. Nature (2006) 1.58
The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development (2005) 1.55
Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels. Proc Natl Acad Sci U S A (2008) 1.53
An obligatory role of mind bomb-1 in notch signaling of mammalian development. PLoS One (2007) 1.53
Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism. Proc Natl Acad Sci U S A (2010) 1.51
Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron (2012) 1.50
Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma among women in Connecticut. Hum Genet (2006) 1.47
The coiled-coil protein shrub controls neuronal morphogenesis in Drosophila. Curr Biol (2006) 1.46
Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein. Neuron (2011) 1.38
The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron (2006) 1.37
Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell (2005) 1.36
Dividing glial cells maintain differentiated properties including complex morphology and functional synapses. Proc Natl Acad Sci U S A (2008) 1.36
Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam. Genes Dev (2012) 1.33
Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity. Proc Natl Acad Sci U S A (2004) 1.32
Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. J Mol Med (Berl) (2011) 1.32
Lethal giant larvae acts together with numb in notch inhibition and cell fate specification in the Drosophila adult sensory organ precursor lineage. Curr Biol (2003) 1.29
The mammalian Golgi regulates numb signaling in asymmetric cell division by releasing ACBD3 during mitosis. Cell (2007) 1.27
The Drosophila myosin VI Jaguar is required for basal protein targeting and correct spindle orientation in mitotic neuroblasts. Dev Cell (2003) 1.26
Voltage-gated potassium channels and the diversity of electrical signalling. J Physiol (2012) 1.22
G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation. Proc Natl Acad Sci U S A (2008) 1.21
A putative exonic splicing polymorphism in the BCL6 gene and the risk of non-Hodgkin lymphoma. J Natl Cancer Inst (2005) 1.20
Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity. Proc Natl Acad Sci U S A (2006) 1.19
A fluorescent probe designed for studying protein conformational change. Proc Natl Acad Sci U S A (2005) 1.17
Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN. Neuron (2006) 1.16
Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1. Development (2011) 1.15
The S4 voltage sensor packs against the pore domain in the KAT1 voltage-gated potassium channel. Neuron (2005) 1.15
Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. Genes Dev (2007) 1.12
Sound response mediated by the TRP channels NOMPC, NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae. Proc Natl Acad Sci U S A (2013) 1.09
Dendritic development: lessons from Drosophila and related branches. Curr Opin Neurobiol (2004) 1.09
Light-induced structural and functional plasticity in Drosophila larval visual system. Science (2011) 1.07
Variations on the Notch pathway in neural development. Curr Opin Neurobiol (2002) 1.05
Vaccines against epidemic and pandemic influenza. Expert Opin Drug Deliv (2008) 1.04
Menstrual and reproductive factors and risk of non-Hodgkin's lymphoma among Connecticut women. Am J Epidemiol (2004) 1.04
Differential regulation of dendritic and axonal development by the novel Krüppel-like factor Dar1. J Neurosci (2011) 1.04
Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proc Natl Acad Sci U S A (2013) 1.02
The Notch regulator Numb links the Notch and TCR signaling pathways. J Immunol (2005) 1.01
NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection. Proc Natl Acad Sci U S A (2004) 1.00
Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance. J Mol Biol (2004) 1.00
The enigma of the numb-Notch relationship during mammalian embryogenesis. Dev Neurosci (2006) 0.99
Nestin promoter/enhancer directs transgene expression to precursors of adult generated periglomerular neurons. J Comp Neurol (2004) 0.99
Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma. Am J Epidemiol (2007) 0.99
Blood transfusion and risk of non-Hodgkin's lymphoma in Connecticut women. Am J Epidemiol (2004) 0.98
Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs. Mol Biol Cell (2005) 0.98
The Tsc1-Tsc2 complex influences neuronal polarity by modulating TORC1 activity and SAD levels. Genes Dev (2008) 0.95
SK channels mediate NADPH oxidase-independent reactive oxygen species production and apoptosis in granulocytes. Proc Natl Acad Sci U S A (2006) 0.94
Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels. Proc Natl Acad Sci U S A (2005) 0.94
Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway. Mol Cell Biol (2005) 0.94
Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev (2004) 0.93
Bazooka is a permissive factor for the invasive behavior of discs large tumor cells in Drosophila ovarian follicular epithelia. Development (2003) 0.92
Increased neuronal activity fragments the Golgi complex. Proc Natl Acad Sci U S A (2013) 0.92