1
|
The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis.
|
Cell
|
2009
|
5.33
|
2
|
Wnt3a plays a major role in the segmentation clock controlling somitogenesis.
|
Dev Cell
|
2003
|
3.15
|
3
|
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.
|
Development
|
2007
|
2.70
|
4
|
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.
|
Development
|
2005
|
2.36
|
5
|
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition.
|
Cancer Cell
|
2008
|
2.12
|
6
|
DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries.
|
Blood
|
2009
|
2.07
|
7
|
Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.
|
Dev Cell
|
2006
|
2.06
|
8
|
Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms.
|
Immunity
|
2008
|
2.05
|
9
|
Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.
|
Proc Natl Acad Sci U S A
|
2006
|
1.76
|
10
|
WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos.
|
Genes Dev
|
2004
|
1.74
|
11
|
Expression of Notch pathway components in fetal and adult mouse small intestine.
|
Gene Expr Patterns
|
2002
|
1.72
|
12
|
Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies.
|
Cell Stem Cell
|
2011
|
1.67
|
13
|
Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons.
|
Nat Neurosci
|
2006
|
1.61
|
14
|
Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms.
|
Dev Cell
|
2007
|
1.59
|
15
|
Notch ligand Delta-like 1 is essential for postnatal arteriogenesis.
|
Circ Res
|
2007
|
1.54
|
16
|
The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments.
|
Genes Dev
|
2004
|
1.46
|
17
|
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.
|
J Cell Biol
|
2007
|
1.39
|
18
|
Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites.
|
Development
|
2003
|
1.32
|
19
|
A critical role for notch signaling in the formation of cholangiocellular carcinomas.
|
Cancer Cell
|
2013
|
1.30
|
20
|
Transcriptional oscillation of lunatic fringe is essential for somitogenesis.
|
Genes Dev
|
2003
|
1.29
|
21
|
The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation.
|
Genes Dev
|
2004
|
1.17
|
22
|
Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signalling and Tbx6.
|
EMBO Rep
|
2007
|
1.17
|
23
|
The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.
|
Proc Natl Acad Sci U S A
|
2007
|
1.17
|
24
|
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.
|
Am J Physiol Lung Cell Mol Physiol
|
2009
|
1.12
|
25
|
Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis.
|
J Invest Dermatol
|
2007
|
1.11
|
26
|
The mouse rib-vertebrae mutation is a hypomorphic Tbx6 allele.
|
Mech Dev
|
2002
|
1.08
|
27
|
Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.
|
Genes Dev
|
2008
|
1.06
|
28
|
Specification of vertebral identity is coupled to Notch signalling and the segmentation clock.
|
Development
|
2004
|
1.05
|
29
|
Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons.
|
Dev Biol
|
2006
|
1.00
|
30
|
Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity.
|
Dev Biol
|
2009
|
1.00
|
31
|
Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.
|
Dev Biol
|
2002
|
0.98
|
32
|
Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development.
|
BMC Dev Biol
|
2009
|
0.89
|
33
|
Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.
|
Development
|
2012
|
0.89
|
34
|
Identification of mouse genes with highly specific expression patterns in differentiated intestinal epithelium.
|
Gastroenterology
|
2006
|
0.86
|
35
|
Cloning and characterization of the mammalian-specific nicolin 1 gene (NICN1) encoding a nuclear 24 kDa protein.
|
Eur J Biochem
|
2002
|
0.84
|
36
|
α5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice.
|
PLoS One
|
2011
|
0.84
|
37
|
A novel mammal-specific three partite enhancer element regulates node and notochord-specific Noto expression.
|
PLoS One
|
2012
|
0.80
|
38
|
S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development.
|
Mol Cell Biol
|
2014
|
0.79
|
39
|
Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints.
|
BMC Dev Biol
|
2007
|
0.78
|
40
|
Normal development in mice over-expressing the intracellular domain of DLL1 argues against reverse signaling by DLL1 in vivo.
|
PLoS One
|
2013
|
0.78
|
41
|
A Critical Role for Notch Signaling in the Formation of Cholangiocellular Carcinomas.
|
Cancer Cell
|
2016
|
0.76
|