Achim Gossler

Author PubWeight™ 58.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 2009 5.33
2 Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell 2003 3.15
3 Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development 2007 2.70
4 The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development 2005 2.36
5 Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. Cancer Cell 2008 2.12
6 DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. Blood 2009 2.07
7 Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Dev Cell 2006 2.06
8 Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms. Immunity 2008 2.05
9 Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants. Proc Natl Acad Sci U S A 2006 1.76
10 WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes Dev 2004 1.74
11 Expression of Notch pathway components in fetal and adult mouse small intestine. Gene Expr Patterns 2002 1.72
12 Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies. Cell Stem Cell 2011 1.67
13 Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons. Nat Neurosci 2006 1.61
14 Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms. Dev Cell 2007 1.59
15 Notch ligand Delta-like 1 is essential for postnatal arteriogenesis. Circ Res 2007 1.54
16 The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev 2004 1.46
17 Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo. J Cell Biol 2007 1.39
18 Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites. Development 2003 1.32
19 A critical role for notch signaling in the formation of cholangiocellular carcinomas. Cancer Cell 2013 1.30
20 Transcriptional oscillation of lunatic fringe is essential for somitogenesis. Genes Dev 2003 1.29
21 The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation. Genes Dev 2004 1.17
22 Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signalling and Tbx6. EMBO Rep 2007 1.17
23 The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning. Proc Natl Acad Sci U S A 2007 1.17
24 Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol 2009 1.12
25 Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. J Invest Dermatol 2007 1.11
26 The mouse rib-vertebrae mutation is a hypomorphic Tbx6 allele. Mech Dev 2002 1.08
27 Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation. Genes Dev 2008 1.06
28 Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development 2004 1.05
29 Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol 2006 1.00
30 Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Dev Biol 2009 1.00
31 Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice. Dev Biol 2002 0.98
32 Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development. BMC Dev Biol 2009 0.89
33 Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1. Development 2012 0.89
34 Identification of mouse genes with highly specific expression patterns in differentiated intestinal epithelium. Gastroenterology 2006 0.86
35 Cloning and characterization of the mammalian-specific nicolin 1 gene (NICN1) encoding a nuclear 24 kDa protein. Eur J Biochem 2002 0.84
36 α5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice. PLoS One 2011 0.84
37 A novel mammal-specific three partite enhancer element regulates node and notochord-specific Noto expression. PLoS One 2012 0.80
38 S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development. Mol Cell Biol 2014 0.79
39 Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints. BMC Dev Biol 2007 0.78
40 Normal development in mice over-expressing the intracellular domain of DLL1 argues against reverse signaling by DLL1 in vivo. PLoS One 2013 0.78
41 A Critical Role for Notch Signaling in the Formation of Cholangiocellular Carcinomas. Cancer Cell 2016 0.76