Published in Hum Immunol on September 24, 2007
The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D). Mol Psychiatry (2012) 1.41
Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells. J Immunol (2013) 0.95
The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists. J Biol Chem (2012) 0.92
Secretion of the human Toll-like receptor 3 ectodomain is affected by single nucleotide polymorphisms and regulated by Unc93b1. J Biol Chem (2010) 0.92
Mutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3' splice site in vivo. PLoS Genet (2009) 0.87
No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice. Nat Immunol (2013) 0.85
The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing. PLoS Genet (2012) 0.79
Respond to "No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice". Nat Immunol (2013) 0.75
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci U S A (2006) 8.27
Type I interferons (alpha/beta) in immunity and autoimmunity. Annu Rev Immunol (2005) 7.74
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature (2005) 7.72
Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science (2006) 6.47
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol (2006) 5.51
CCR7 and its ligands: balancing immunity and tolerance. Nat Rev Immunol (2008) 5.35
CD14 is required for MyD88-independent LPS signaling. Nat Immunol (2005) 5.20
CD36 is a sensor of diacylglycerides. Nature (2005) 5.20
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci U S A (2004) 4.88
Intracellular toll-like receptors. Immunity (2010) 4.66
Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science (2009) 4.45
Herpes simplex virus encephalitis in human UNC-93B deficiency. Science (2006) 4.26
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol (2003) 4.15
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J Cell Biol (2007) 3.72
The serine protease TMPRSS6 is required to sense iron deficiency. Science (2008) 3.70
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity. Nat Med (2007) 3.45
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity (2007) 3.38
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J Exp Med (2003) 3.30
The interface between innate and adaptive immunity. Nat Immunol (2004) 3.28
The chemokine receptor D6 limits the inflammatory response in vivo. Nat Immunol (2005) 2.98
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2. J Biol Chem (2007) 2.82
Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev (2010) 2.63
The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. Immunity (2011) 2.41
CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells. J Exp Med (2007) 2.39
Genome-wide functional analysis of human cell-cycle regulators. Proc Natl Acad Sci U S A (2006) 2.31
CXCR7 functions as a scavenger for CXCL12 and CXCL11. PLoS One (2010) 2.28
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer. Cancer Cell (2004) 2.27
Plant and animal sensors of conserved microbial signatures. Science (2010) 2.16
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The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity. Nat Immunol (2008) 2.08
Cutting edge: Priming of NK cells by IL-18. J Immunol (2008) 2.08
B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy. J Immunol (2003) 2.08
Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery. PLoS Biol (2009) 2.07
Toll-like receptors. Curr Biol (2011) 2.06
Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science (2012) 1.98
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow. Nat Immunol (2011) 1.96
Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway. Virology (2007) 1.94
Wapl is an essential regulator of chromatin structure and chromosome segregation. Nature (2013) 1.92
Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells. Nat Immunol (2005) 1.90
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis. Proc Natl Acad Sci U S A (2006) 1.88
Chemokine/chemokine receptor nomenclature. J Interferon Cytokine Res (2002) 1.86
ATP-sensitive potassium channels mediate survival during infection in mammals and insects. Nat Genet (2007) 1.83
mRNA openers and closers: modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure. Chembiochem (2004) 1.82
CCR7 deficiency exacerbates injury in acute nephritis due to aberrant localization of regulatory T cells. J Am Soc Nephrol (2009) 1.79
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility. Proc Natl Acad Sci U S A (2003) 1.78
Efficient T cell activation via a Toll-Interleukin 1 Receptor-independent pathway. Immunity (2006) 1.78
An essential role for Rxr alpha in the development of Th2 responses. Eur J Immunol (2005) 1.74
Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis. J Exp Med (2007) 1.73
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands. Proc Natl Acad Sci U S A (2010) 1.73
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response. Proc Natl Acad Sci U S A (2009) 1.69
The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung. J Immunol (2005) 1.65
Triggering the succinate receptor GPR91 on dendritic cells enhances immunity. Nat Immunol (2008) 1.61
The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines. Mol Biol Cell (2004) 1.60
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proc Natl Acad Sci U S A (2011) 1.59
Rapid identification of a disease allele in mouse through whole genome sequencing and bulk segregation analysis. Genetics (2010) 1.56
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells. Proc Natl Acad Sci U S A (2010) 1.55
A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria. Infect Immun (2005) 1.55
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing. J Exp Med (2009) 1.53
An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs. PLoS One (2011) 1.53
Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors. Immunity (2007) 1.50
The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis. EMBO J (2012) 1.50
Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells. Genome Biol (2008) 1.46
LPS, dsRNA and the interferon bridge to adaptive immune responses: Trif, Tram, and other TIR adaptor proteins. J Endotoxin Res (2004) 1.42
Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats. J Cereb Blood Flow Metab (2003) 1.42
Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling. J Immunol (2005) 1.42
The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc Natl Acad Sci U S A (2004) 1.41
An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence. Nat Immunol (2010) 1.39
Identification of a TLR4- and TRIF-dependent activation program of dendritic cells. Eur J Immunol (2004) 1.39
Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators. Cell Signal (2005) 1.39
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc Natl Acad Sci U S A (2005) 1.39
Murine cerebral malaria development is independent of toll-like receptor signaling. Am J Pathol (2007) 1.38
Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening. J Endotoxin Res (2003) 1.38
A model for familial exudative vitreoretinopathy caused by LPR5 mutations. Hum Mol Genet (2008) 1.36
Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: comparison with human. PLoS One (2008) 1.36
Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6. Br J Haematol (2009) 1.36
Mechanism of pathogen-specific TLR4 activation in the mucosa: fimbriae, recognition receptors and adaptor protein selection. Eur J Immunol (2006) 1.32
Sensors of the innate immune system: their mode of action. Nat Rev Rheumatol (2009) 1.31
Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J Immunol (2004) 1.31
NK-cell-mediated killing of target cells triggers robust antigen-specific T-cell-mediated and humoral responses. Blood (2009) 1.29
ENU-induced phenovariance in mice: inferences from 587 mutations. BMC Res Notes (2012) 1.28
Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice. Genetics (2004) 1.28
R-form LPS, the master key to the activation ofTLR4/MD-2-positive cells. Eur J Immunol (2006) 1.27
Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha. J Biol Chem (2002) 1.26
Analysis of the MCMV resistome by ENU mutagenesis. Mamm Genome (2006) 1.23
The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. EMBO J (2011) 1.22
The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules. Traffic (2008) 1.22
UNC93B1 mediates host resistance to infection with Toxoplasma gondii. PLoS Pathog (2010) 1.22
Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions. Platelets (2004) 1.21
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci U S A (2012) 1.19
Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: benefits and hazards of LPS hypersensitivity. Immunobiology (2007) 1.18
Chemokines on the move: control by the chemokine "interceptors" Duffy blood group antigen and D6. Semin Immunol (2003) 1.18
The effect of RNA secondary structures on RNA-ligand binding and the modifier RNA mechanism: a quantitative model. Gene (2005) 1.17
Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes. Biochem J (2007) 1.17
1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype. J Immunol (2009) 1.16
The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis. J Cell Biol (2010) 1.16
Bulk segregation mapping of mutations in closely related strains of mice. Genetics (2010) 1.15
Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations. PLoS Genet (2013) 1.14
A catechol-O-methyltransferase that is essential for auditory function in mice and humans. Proc Natl Acad Sci U S A (2008) 1.13
Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice. J Immunol (2010) 1.13