Published in Differentiation on January 03, 2008
Role of p53 in neurodegenerative diseases. Neurodegener Dis (2011) 0.86
NGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling. PLoS One (2011) 0.84
p53 and MDM2 are involved in the regulation of osteocalcin gene expression. Exp Cell Res (2012) 0.79
Identification of novel target genes of nerve growth factor (NGF) in human mastocytoma cell line (HMC-1 (V560G c-Kit)) by transcriptome analysis. BMC Genomics (2011) 0.77
Claulansine F promotes neuritogenesis in PC12 cells via the ERK signaling pathway. Acta Pharmacol Sin (2013) 0.75
Wnt7b Signaling from the Ureteric Bud Epithelium Regulates Medullary Capillary Development. J Am Soc Nephrol (2016) 0.75
Surfing the p53 network. Nature (2000) 35.36
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature (1992) 25.54
The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol (2004) 24.63
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell (1990) 10.99
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell (2003) 7.93
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol (2006) 7.36
Wnt signalling regulates adult hippocampal neurogenesis. Nature (2005) 6.66
Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem (2006) 6.32
Wnt signaling in disease and in development. Cell Res (2005) 5.53
Transcription factor YY1: structure, function, and therapeutic implications in cancer biology. Oncogene (2006) 4.06
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature (1990) 3.92
WNTs in the vertebrate nervous system: from patterning to neuronal connectivity. Nat Rev Neurosci (2005) 3.39
A subset of p53-deficient embryos exhibit exencephaly. Nat Genet (1995) 3.24
Yin Yang 1 is a negative regulator of p53. Cell (2004) 3.24
hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage. Cell (2005) 3.18
A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling. Trends Biochem Sci (2000) 3.09
The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development (2004) 2.94
Wnt7b regulates mesenchymal proliferation and vascular development in the lung. Development (2002) 2.88
TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta. J Biol Chem (2004) 2.84
Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nat Neurosci (2004) 2.81
Catenins: keeping cells from getting their signals crossed. Dev Cell (2006) 2.70
Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation. Dev Cell (2007) 2.41
Differential transformation of mammary epithelial cells by Wnt genes. Mol Cell Biol (1994) 2.37
SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription. J Biol Chem (2002) 1.92
Outcomes of p53 activation--spoilt for choice. J Cell Sci (2006) 1.88
Wnt/beta-catenin signaling. Cytokine Growth Factor Rev (2000) 1.86
Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. J Biol Chem (2004) 1.85
Caspase and calpain substrates: roles in synaptic plasticity and cell death. J Neurosci Res (1999) 1.80
Tissue-specific induction of p53 targets in vivo. Cancer Res (2002) 1.79
Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Mol Cell Biol (2005) 1.79
Wnt signaling: multiple functions in neural development. Cell Mol Life Sci (2005) 1.64
Regulation of the differentiation of PC12 pheochromocytoma cells. Environ Health Perspect (1989) 1.62
The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium. J Biol Chem (2002) 1.59
Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool. Oncogene (2001) 1.57
The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration. EMBO J (2006) 1.54
Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity. J Cell Biol (2006) 1.53
Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins. J Biol Chem (2003) 1.44
Manipulating gene expressions by electroporation in the developing brain of mammalian embryos. Differentiation (2002) 1.40
The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem (2000) 1.40
Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum. J Biol Chem (2002) 1.39
Wnt7b regulates placental development in mice. Dev Biol (2001) 1.37
Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion interval. Development (2005) 1.35
A novel, nerve growth factor-activated pathway involving nitric oxide, p53, and p21WAF1 regulates neuronal differentiation of PC12 cells. J Biol Chem (1997) 1.16
Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties. Exp Cell Res (1995) 1.15
Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium. J Cell Sci (2000) 1.12
p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells. Mol Cell Biol (1996) 1.06
Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids. Oncogene (2006) 1.05
Mediation of nerve growth factor-driven cell cycle arrest in PC12 cells by p53. Simultaneous differentiation and proliferation subsequent to p53 functional inactivation. J Biol Chem (2000) 1.04
Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth. Differentiation (2005) 0.98
p53 is required for nerve growth factor-mediated differentiation of PC12 cells via regulation of TrkA levels. Cell Death Differ (2006) 0.96
Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev Dyn (2006) 0.96
Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain. Exp Cell Res (2006) 0.96
Tissue-specific p53 responses to ionizing radiation and their genetic modification: the key to tissue-specific tumour susceptibility? J Pathol (2003) 0.94
Apoptosis mediated by p53 in rat neural AF5 cells following treatment with hydrogen peroxide and staurosporine. Brain Res (2006) 0.94
NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation. BMC Genomics (2007) 0.93
Frizzled7 mediates canonical Wnt signaling in neural crest induction. Dev Biol (2006) 0.92
The effects of a mutant p53 protein on the proliferation and differentiation of PC12 rat phaeochromocytoma cells. J Cell Biochem (2006) 0.92
Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells. Mol Cell Biol (2007) 0.92
p53 expression in the normal murine eye. Invest Ophthalmol Vis Sci (2002) 0.88
Nerve growth factor potentiates p53 DNA binding but inhibits nitric oxide-induced apoptosis in neuronal PC12 cells. Neurochem Res (2007) 0.81
Colostrinin-driven neurite outgrowth requires p53 activation in PC12 cells. Cell Mol Neurobiol (2005) 0.80
Gene expression and apoptosis induction in p53-heterozygous irradiated mice. Mutat Res (2005) 0.80
frizzled 9 is expressed in neural precursor cells in the developing neural tube. Dev Genes Evol (2001) 0.79
Differential expression of Wnt genes in normal and flat variants of PC12 cells, a cell line responsive to ectopic Wnt1 expression. Growth Factors (1998) 0.77
CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data. Nucleic Acids Res (2007) 1.80
Global gene expression associated with hepatocarcinogenesis in adult male mice induced by in utero arsenic exposure. Environ Health Perspect (2006) 1.30
Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype. Genome Biol (2008) 1.28
Quantitative proteomics analysis of macrophage rafts reveals compartmentalized activation of the proteasome and of proteasome-mediated ERK activation in response to lipopolysaccharide. Mol Cell Proteomics (2008) 1.07
CEBS object model for systems biology data, SysBio-OM. Bioinformatics (2004) 1.02
Differential gene expression profiling in whole blood during acute systemic inflammation in lipopolysaccharide-treated rats. Physiol Genomics (2005) 1.01
Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation. Cell Metab (2010) 1.01
Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data. Toxicol Sci (2005) 1.01
Toxicoproteomics: proteomics applied to toxicology and pathology. Toxicol Pathol (2004) 0.97
Bisphenol A affects androgen receptor function via multiple mechanisms. Chem Biol Interact (2013) 0.95
Apoptosis mediated by p53 in rat neural AF5 cells following treatment with hydrogen peroxide and staurosporine. Brain Res (2006) 0.94
NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation. BMC Genomics (2007) 0.93
Chemical effects in biological systems (CEBS) object model for toxicology data, SysTox-OM: design and application. Bioinformatics (2006) 0.90
p53 Integrates host defense and cell fate during bacterial pneumonia. J Exp Med (2013) 0.89
Transplacental arsenic plus postnatal 12-O-teradecanoyl phorbol-13-acetate exposures associated with hepatocarcinogenesis induce similar aberrant gene expression patterns in male and female mouse liver. Toxicol Appl Pharmacol (2005) 0.88
Exploration of low-dose estrogen effects: identification of No Observed Transcriptional Effect Level (NOTEL). Toxicol Pathol (2004) 0.82
Effects of TCDD upon IkappaB and IKK subunits localized in microsomes by proteomics. Arch Biochem Biophys (2002) 0.79
Toxicoproteomics: a parallel approach to identifying biomarkers. Environ Health Perspect (2003) 0.76