Published in Curr Diabetes Rev on May 01, 2005
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Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes (2005) 2.35
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Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle. Diabetes (2008) 2.03
Glutamate is a positive autocrine signal for glucagon release. Cell Metab (2008) 2.01
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance. Cell (2008) 1.97
The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle. J Biol Chem (2004) 1.94
T cell-mediated inflammation in adipose tissue does not cause insulin resistance in hyperlipidemic mice. Circ Res (2009) 1.93
Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects. Diabetes (2005) 1.89
AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits. Diabetes (2006) 1.85
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth. PLoS Biol (2009) 1.61
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Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans. FASEB J (2005) 1.55
MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance. J Biol Chem (2007) 1.53
Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways. J Biol Chem (2003) 1.53
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Cell Metab (2006) 1.48
Strenuous physical exercise adversely affects monocyte chemotaxis. Thromb Haemost (2010) 1.45
5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes. Diabetes (2003) 1.45
Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle. Mol Endocrinol (2006) 1.43
Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle. Diabetes (2007) 1.37
Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle. Diabetes (2006) 1.37
Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle. Am J Physiol Endocrinol Metab (2003) 1.32
Weight loss after gastric bypass surgery in human obesity remodels promoter methylation. Cell Rep (2013) 1.31
Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity. Diabetes Metab Res Rev (2011) 1.30
Changes in exercise-induced gene expression in 5'-AMP-activated protein kinase gamma3-null and gamma3 R225Q transgenic mice. Diabetes (2005) 1.29
Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta. Diabetes (2005) 1.28
Analysis of paradoxical observations on the association between leptin and insulin resistance. FASEB J (2002) 1.28
Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation. J Biol Chem (2009) 1.27
Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients. Diabetes (2006) 1.19
Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes. Am J Physiol Endocrinol Metab (2012) 1.19
Calcineurin regulates skeletal muscle metabolism via coordinated changes in gene expression. J Biol Chem (2006) 1.18
Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle. J Biol Chem (2008) 1.17
MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways. Am J Physiol Cell Physiol (2004) 1.16
Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training. J Physiol (2013) 1.16
USF1 and dyslipidemias: converging evidence for a functional intronic variant. Hum Mol Genet (2005) 1.16
Sending the signal: molecular mechanisms regulating glucose uptake. Med Sci Sports Exerc (2004) 1.15
Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise. J Physiol (2003) 1.13
DNA methylation in metabolic disorders. Am J Clin Nutr (2011) 1.11
Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev (2006) 1.11
Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study. Diabetes (2005) 1.10
IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients. Diabetes (2006) 1.10
Insulin signaling and glucose transport in insulin resistant human skeletal muscle. Cell Biochem Biophys (2007) 1.10
5'-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics. FASEB J (2005) 1.09
Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes. J Clin Endocrinol Metab (2004) 1.08
Adenosine 5'-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle. Endocrinology (2008) 1.05
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The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism. Am J Physiol Endocrinol Metab (2012) 1.02
Insulin signaling defects in type 2 diabetes. Rev Endocr Metab Disord (2004) 1.02
siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle. Diabetes (2008) 1.02
Kinetics of GLUT4 trafficking in rat and human skeletal muscle. Diabetes (2009) 1.01
Opposite transcriptional regulation in skeletal muscle of AMP-activated protein kinase gamma3 R225Q transgenic versus knock-out mice. J Biol Chem (2006) 0.99
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Isoform-specific regulation of 5' AMP-activated protein kinase in skeletal muscle from obese Zucker (fa/fa) rats in response to contraction. Diabetes (2002) 0.99
Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle. Am J Physiol Endocrinol Metab (2008) 0.99
Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes. Diabetes (2012) 0.98
Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus. Metabolism (2011) 0.97
Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7. Am J Physiol Endocrinol Metab (2013) 0.97
The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells. Mol Immunol (2010) 0.95
Divergent cell signaling after short-term intensified endurance training in human skeletal muscle. Am J Physiol Endocrinol Metab (2008) 0.95
Signalling mechanisms in skeletal muscle: role in substrate selection and muscle adaptation. Essays Biochem (2006) 0.94
Time course analysis reveals gene-specific transcript and protein kinetics of adaptation to short-term aerobic exercise training in human skeletal muscle. PLoS One (2013) 0.94
Impaired insulin action on phosphatidylinositol 3-kinase activity and glucose transport in skeletal muscle of pancreatic cancer patients. Pancreas (2003) 0.94
Evidence for non-CpG methylation in mammals. Exp Cell Res (2011) 0.94
Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats. Endocrinology (2003) 0.93
AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase. Am J Physiol Cell Physiol (2009) 0.93
Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity. Am J Physiol Endocrinol Metab (2009) 0.92
Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle. Endocrinology (2013) 0.92
Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle. Endocrinology (2008) 0.92
Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling. Mol Endocrinol (2008) 0.92
Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle. J Biol Chem (2011) 0.91
Exercise-induced protein kinase C isoform-specific activation in human skeletal muscle. Diabetes (2004) 0.91
Neuregulins mediate calcium-induced glucose transport during muscle contraction. J Biol Chem (2006) 0.90
2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training. Proteomics (2011) 0.90
Altered response of skeletal muscle to IL-6 in type 2 diabetic patients. Diabetes (2012) 0.89
AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle. J Physiol (2013) 0.89
Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle. Am J Physiol Endocrinol Metab (2013) 0.88
Effects of insulin, contraction, and phorbol esters on mitogen-activated protein kinase signaling in skeletal muscle from lean and ob/ob mice. Diabetes (2004) 0.87
Relationship between serum amyloid A level and Tanis/SelS mRNA expression in skeletal muscle and adipose tissue from healthy and type 2 diabetic subjects. Diabetes (2004) 0.87
Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells. J Biol Chem (2012) 0.85
Angiopoietin-like 4 mediates PPAR delta effect on lipoprotein lipase-dependent fatty acid uptake but not on beta-oxidation in myotubes. PLoS One (2012) 0.85
Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise. Int J Mol Med (2006) 0.85
Expression of carnitine palmitoyl-CoA transferase-1B is influenced by a cis-acting eQTL in two chicken lines selected for high and low body weight. Physiol Genomics (2013) 0.84
Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake. Am J Physiol Endocrinol Metab (2004) 0.84
Hunting for the SNARK in metabolic disease. Am J Physiol Endocrinol Metab (2009) 0.83
Influence of AMP-activated protein kinase and calcineurin on metabolic networks in skeletal muscle. Am J Physiol Endocrinol Metab (2008) 0.83
Effect of leptin treatment on mitochondrial function in obese leptin-deficient ob/ob mice. Metabolism (2013) 0.82