PubRank

Edward W Harhaj

Author PubWeight™ 38.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. Science 2010 4.03
2 The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20. Nat Immunol 2008 3.55
3 Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. J Biol Chem 2004 3.35
4 The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling. EMBO J 2009 2.17
5 Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling. EMBO J 2007 1.95
6 The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation. J Virol 2007 1.66
7 ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways. Curr Biol 2009 1.34
8 Regulation of NF-κB signaling by the A20 deubiquitinase. Cell Mol Immunol 2012 1.33
9 TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases. J Biol Chem 2010 1.29
10 Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase. J Biol Chem 2006 1.23
11 Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax. J Biol Chem 2003 1.20
12 IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphoma. Blood 2007 1.06
13 The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1. Nat Immunol 2011 1.05
14 Human T cell leukemia virus type 1 Tax inhibits innate antiviral signaling via NF-kappaB-dependent induction of SOCS1. J Virol 2011 1.05
15 Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing complex between Tax and CREB. Retrovirology 2015 0.97
16 ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling. J Biol Chem 2011 0.95
17 An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation. J Virol 2012 0.94
18 Regulation of inflammatory and antiviral signaling by A20. Microbes Infect 2010 0.92
19 RING finger protein 11 targets TBK1/IKKi kinases to inhibit antiviral signaling. PLoS One 2013 0.89
20 Deregulated expression of CD40 ligand in HTLV-I infection: distinct mechanisms of downregulation in HTLV-I-transformed cell lines and ATL patients. Virology 2007 0.88
21 Role of post-translational modifications of HTLV-1 Tax in NF-κB activation. World J Biol Chem 2010 0.84
22 EBV LMP1: New and shared pathways to NF-κB activation. Proc Natl Acad Sci U S A 2012 0.82
23 Mediators of central nervous system damage during the progression of human T-cell leukemia type I-associated myelopathy/tropical spastic paraparesis. J Neurovirol 2003 0.80
24 Cell signaling. Anchors away for ubiquitin chains. Science 2010 0.78
25 Outfoxing FoxO transcription factors: HTLV-1 Tax oncoprotein inactivates FoxO4 via the ubiquitin-proteasome pathway. Future Virol 2011 0.76
26 Elucidating dynamic protein-protein interactions and ubiquitination in NF-κB signaling pathways. Methods Mol Biol 2015 0.76
27 IKKi: a novel regulator of Act1, IL-17 signaling and pulmonary inflammation. Cell Mol Immunol 2011 0.76
28 Is there a role for ubiquitin or SUMO in human T-cell leukemia virus type 2 Tax-induced NF-κB activation? Future Virol 2013 0.75
29 The NLRP4-DTX4 axis: a key suppressor of TBK1 and innate antiviral signaling. Cell Mol Immunol 2012 0.75
30 Role of the proteasome in the downregulation of transcription factors NFkappaB and C/EBP in macrophages from tumor hosts. Oncol Rep 2010 0.75