The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20.

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Published in Nat Immunol on February 03, 2008

Authors

Noula Shembade1, Nicole S Harhaj, Kislay Parvatiyar, Neal G Copeland, Nancy A Jenkins, Lydia E Matesic, Edward W Harhaj

Author Affiliations

1: Department of Microbiology and Immunology, Sylvester Comprehensive Cancer Center, The University of Miami, Miller School of Medicine, Miami, Florida 33136, USA.

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