PubRank

Dale W Laird

Author PubWeight™ 85.18‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Multicolor and electron microscopic imaging of connexin trafficking. Science 2002 5.60
2 Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature 2010 4.10
3 Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. J Cell Sci 2007 2.41
4 A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development 2005 1.93
5 Implications and challenges of connexin connections to cancer. Nat Rev Cancer 2010 1.85
6 Pannexin channels are not gap junction hemichannels. Channels (Austin) 2011 1.84
7 Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia. J Biol Chem 2011 1.76
8 The biochemistry and function of pannexin channels. Biochim Biophys Acta 2012 1.70
9 Gap junction remodeling in skin repair following wounding and disease. Physiology (Bethesda) 2013 1.49
10 Connexins act as tumor suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis. Cancer Res 2006 1.48
11 Oculodentodigital dysplasia-causing connexin43 mutants are non-functional and exhibit dominant effects on wild-type connexin43. J Biol Chem 2005 1.46
12 Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis. J Mol Med (Berl) 2015 1.45
13 Glycosylation regulates pannexin intermixing and cellular localization. Mol Biol Cell 2009 1.45
14 Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication. J Biol Chem 2002 1.37
15 Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells. J Biol Chem 2003 1.32
16 Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture. Breast Cancer Res 2005 1.27
17 Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes. Mol Biol Cell 2007 1.23
18 Evaluation of mammary gland development and function in mouse models. J Vis Exp 2011 1.22
19 Mechanisms of Cx43 and Cx26 transport to the plasma membrane and gap junction regeneration. J Cell Sci 2005 1.21
20 Pannexin1 regulates α1-adrenergic receptor- mediated vasoconstriction. Circ Res 2011 1.21
21 Down-regulation of Cx43 by retroviral delivery of small interfering RNA promotes an aggressive breast cancer cell phenotype. Cancer Res 2005 1.17
22 Connexins and gap junctions in mammary gland development and breast cancer progression. J Membr Biol 2007 1.15
23 Functional characterization of a GJA1 frameshift mutation causing oculodentodigital dysplasia and palmoplantar keratoderma. J Biol Chem 2006 1.10
24 Differential potency of dominant negative connexin43 mutants in oculodentodigital dysplasia. J Biol Chem 2007 1.10
25 Selective assembly of connexin37 into heterocellular gap junctions at the oocyte/granulosa cell interface. J Cell Sci 2004 1.09
26 Gap junctions assemble in the presence of cytoskeletal inhibitors, but enhanced assembly requires microtubules. Exp Cell Res 2002 1.09
27 Functional characterization of oculodentodigital dysplasia-associated Cx43 mutants. Cell Commun Adhes 2006 1.07
28 Functional domain mapping and selective trans-dominant effects exhibited by Cx26 disease-causing mutations. J Biol Chem 2004 1.03
29 Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions. J Biol Chem 2010 1.03
30 ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation. J Bone Miner Res 2008 1.03
31 The tumor-suppressive function of Connexin43 in keratinocytes is mediated in part via interaction with caveolin-1. Cancer Res 2010 1.01
32 Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes. J Bone Miner Res 2011 0.99
33 Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia. Dev Biol 2008 0.97
34 Mechanisms linking connexin mutations to human diseases. Cell Tissue Res 2014 0.97
35 Implications of pannexin 1 and pannexin 3 for keratinocyte differentiation. J Cell Sci 2010 0.97
36 S-nitrosylation inhibits pannexin 1 channel function. J Biol Chem 2012 0.96
37 Expression of pannexin isoforms in the systemic murine arterial network. J Vasc Res 2012 0.95
38 Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism. Carcinogenesis 2006 0.94
39 Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype. J Biol Chem 2012 0.94
40 Diverse subcellular distribution profiles of pannexin 1 and pannexin 3. Cell Commun Adhes 2008 0.94
41 Fate of connexin43 in cardiac tissue harbouring a disease-linked connexin43 mutant. Cardiovasc Res 2008 0.93
42 The protective effect of functional connexin43 channels on a human epithelial cell line exposed to oxidative stress. Invest Ophthalmol Vis Sci 2008 0.93
43 Cx43 has distinct mobility within plasma-membrane domains, indicative of progressive formation of gap-junction plaques. J Cell Sci 2009 0.92
44 Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression. Proc Natl Acad Sci U S A 2008 0.91
45 A dominant loss-of-function GJA1 (Cx43) mutant impairs parturition in the mouse. Biol Reprod 2009 0.91
46 Connexin levels regulate keratinocyte differentiation in the epidermis. J Biol Chem 2007 0.89
47 Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout. J Comp Neurol 2013 0.89
48 Structure and functional studies of N-terminal Cx43 mutants linked to oculodentodigital dysplasia. Mol Biol Cell 2012 0.88
49 Human dermal fibroblasts derived from oculodentodigital dysplasia patients suggest that patients may have wound-healing defects. Hum Mutat 2011 0.88
50 The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice. Biochem J 2013 0.87
51 Hypoxia and reoxygenation-induced oxidant production increase in microvascular endothelial cells depends on connexin40. Free Radic Biol Med 2010 0.87
52 Transport and function of cx26 mutants involved in skin and deafness disorders. Cell Commun Adhes 2003 0.85
53 Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesis in vivo. J Biol Chem 2013 0.85
54 Oogenesis defects in a mutant mouse model of oculodentodigital dysplasia. Dis Model Mech 2009 0.85
55 The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants. Biochem J 2010 0.84
56 Pannexin1 and Pannexin3 exhibit distinct localization patterns in human skin appendages and are regulated during keratinocyte differentiation and carcinogenesis. Cell Commun Adhes 2012 0.84
57 Beta3 integrins facilitate matrix interactions during transendothelial migration of PC3 prostate tumor cells. Prostate 2005 0.83
58 The G60S Cx43 mutant enhances keratinocyte proliferation and differentiation. Exp Dermatol 2012 0.82
59 Characterization of pannexin1 and pannexin3 and their regulation by androgens in the male reproductive tract of the adult rat. Mol Reprod Dev 2011 0.82
60 Connexin26 regulates the expression of angiogenesis-related genes in human breast tumor cells by both GJIC-dependent and -independent mechanisms. Cell Commun Adhes 2003 0.82
61 Pathways regulating the trafficking and turnover of pannexin1 protein and the role of the C-terminal domain. J Biol Chem 2011 0.82
62 Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged. Biol Reprod 2010 0.82
63 Mutations in Cx30 that are linked to skin disease and non-syndromic hearing loss exhibit several distinct cellular pathologies. J Cell Sci 2014 0.81
64 A histone deacetylation-dependent mechanism for transcriptional repression of the gap junction gene cx43 in prostate cancer cells. Prostate 2006 0.80
65 The effect of connexin43 on the level of vascular endothelial growth factor in human retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol 2011 0.79
66 The G60S connexin43 mutant regulates hair growth and hair fiber morphology in a mouse model of human oculodentodigital dysplasia. J Invest Dermatol 2011 0.79
67 An atrial-fibrillation-linked connexin40 mutant is retained in the endoplasmic reticulum and impairs the function of atrial gap-junction channels. Dis Model Mech 2014 0.78
68 Autosomal recessive GJA1 (Cx43) gene mutations cause oculodentodigital dysplasia by distinct mechanisms. J Cell Sci 2013 0.78
69 Myogenic bladder defects in mouse models of human oculodentodigital dysplasia. Biochem J 2014 0.77
70 Ocular pathology relevant to glaucoma in a Gja1(Jrt/+) mouse model of human oculodentodigital dysplasia. Invest Ophthalmol Vis Sci 2011 0.77
71 CELLULAR SMALL TALK. Sci Am 2015 0.77
72 Rat epidermal keratinocytes as an organotypic model for examining the role of Cx43 and Cx26 in skin differentiation. Cell Commun Adhes 2006 0.77
73 Differentiation of organotypic epidermis in the presence of skin disease-linked dominant-negative Cx26 mutants and knockdown Cx26. J Membr Biol 2007 0.77
74 Critical Role of Cx40 in Reduced Endothelial Electrical Coupling by Lipopolysaccharide and Hypoxia-Reoxygenation. J Vasc Res 2016 0.76
75 Optical and biochemical dissection of connexin and disease-linked connexin mutants in 3D organotypic epidermis. Methods Mol Biol 2010 0.76
76 Gap junctions and cancer: communicating for 50 years. Nat Rev Cancer 2016 0.75
77 Introductory paper of the special issue on gap junctions in honor of Ross Johnson. J Membr Biol 2012 0.75