Candida albicans pathogenicity mechanisms.

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Published in Virulence on January 09, 2013

Authors

François L Mayer1, Duncan Wilson, Bernhard Hube

Author Affiliations

1: Department of Microbial Pathogenicity Mechanisms, Hans-Knoell-Institute, Jena, Germany.

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Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity. J Infect Dis (2013) 1.00

A core filamentation response network in Candida albicans is restricted to eight genes. PLoS One (2013) 0.99

CCR4 in human allergen-induced late responses in the skin and lung. Eur J Immunol (2002) 0.99

The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity. Infect Immun (2010) 0.98

Secreted aspartic proteases of Candida albicans activate the NLRP3 inflammasome. Eur J Immunol (2013) 0.98

Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infect Immun (2010) 0.97

MfLIP1, a gene encoding an extracellular lipase of the lipid-dependent fungus Malassezia furfur. Microbiology (2006) 0.96

The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity factor. PLoS Pathog (2012) 0.95

The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils. Infect Immun (2009) 0.95

Chemical genetics suggests a critical role for lysyl oxidase in zebrafish notochord morphogenesis. Mol Biosyst (2006) 0.95

Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris. BMC Microbiol (2008) 0.94

Fungal adaptation to the host environment. Curr Opin Microbiol (2009) 0.94

Host-pathogen interactions and virulence-associated genes during Candida albicans oral infections. Int J Med Microbiol (2011) 0.94

The role of secreted aspartyl proteinases in Candida albicans keratitis. Invest Ophthalmol Vis Sci (2007) 0.93

Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans. PLoS One (2012) 0.93

Hgc1 mediates dynamic Candida albicans-endothelium adhesion events during circulation. Eukaryot Cell (2009) 0.91

Factors supporting cysteine tolerance and sulfite production in Candida albicans. Eukaryot Cell (2013) 0.90

Candida albicans adhesion to and invasion and damage of vaginal epithelial cells: stage-specific inhibition by clotrimazole and bifonazole. Antimicrob Agents Chemother (2011) 0.90

The early transcriptional response of human granulocytes to infection with Candida albicans is not essential for killing but reflects cellular communications. Infect Immun (2006) 0.89

Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans. Microbiology (2005) 0.89

Pathogenesis of Candida albicans infections in the alternative chorio-allantoic membrane chicken embryo model resembles systemic murine infections. PLoS One (2011) 0.88

Zinc exploitation by pathogenic fungi. PLoS Pathog (2012) 0.88

Chemokine and Fgf signalling act as opposing guidance cues in formation of the lateral line primordium. Development (2012) 0.87

The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion. J Biol Chem (2011) 0.87

Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicans. J Antimicrob Chemother (2005) 0.86

Epithelial invasion outcompetes hypha development during Candida albicans infection as revealed by an image-based systems biology approach. Cytometry A (2013) 0.86

Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice. Eur J Immunol (2014) 0.86

Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans. BMC Microbiol (2008) 0.85

Candida albicans PLD I activity is required for full virulence. Med Mycol (2004) 0.85

Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages. Eukaryot Cell (2013) 0.85

Pathogenicity mechanisms and host response during oral Candida albicans infections. Expert Rev Anti Infect Ther (2014) 0.84

Candida glabrata tryptophan-based pigment production via the Ehrlich pathway. Mol Microbiol (2010) 0.84

Tissue infection and site-specific gene expression in Candida albicans. Adv Appl Microbiol (2003) 0.83