Published in Mamm Genome on February 21, 2008
Obesity, metabolism and the microenvironment: Links to cancer. J Carcinog (2013) 1.07
Genotype X diet interactions in mice predisposed to mammary cancer. I. Body weight and fat. Mamm Genome (2008) 0.89
Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression. Clin Exp Metastasis (2010) 0.88
Role of HGF in obesity-associated tumorigenesis: C3(1)-TAg mice as a model for human basal-like breast cancer. Breast Cancer Res Treat (2013) 0.87
Weight Loss Reversed Obesity-Induced HGF/c-Met Pathway and Basal-Like Breast Cancer Progression. Front Oncol (2014) 0.87
Map making in the 21st century: charting breast cancer susceptibility pathways in rodent models. J Mammary Gland Biol Neoplasia (2011) 0.85
Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis. Clin Exp Metastasis (2010) 0.85
Sex-, diet-, and cancer-dependent epistatic effects on complex traits in mice. Front Genet (2011) 0.84
Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. Am J Physiol Endocrinol Metab (2008) 0.82
High-Fat, High-Calorie Diet Enhances Mammary Carcinogenesis and Local Inflammation in MMTV-PyMT Mouse Model of Breast Cancer. Cancers (Basel) (2015) 0.76
Epistatic Control of Mammary Cancer Susceptibility in Mice may Depend on the Dietary Environment. Hereditary Genet (2012) 0.75
Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science (2003) 13.19
Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol (1992) 12.96
Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst (2003) 6.20
Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. JAMA (2006) 5.51
The genetics and genomics of cancer. Nat Genet (2003) 3.97
The war on cancer. Lancet (1996) 3.38
Diet, nutrition and the prevention of cancer. Public Health Nutr (2004) 3.28
QTL Express: mapping quantitative trait loci in simple and complex pedigrees. Bioinformatics (2002) 3.24
Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Nat Genet (2005) 2.92
Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4. Mol Cell Biol (2002) 2.85
Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1. Cancer Res (2001) 2.06
IGF-I and breast cancer: a meta-analysis. Int J Cancer (2004) 2.03
Lifetime alcohol intake and breast cancer risk. Ann Epidemiol (2005) 1.85
Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer. Breast Cancer Res (2006) 1.81
Effect of dietary fat on human breast cancer growth and lung metastasis in nude mice. J Natl Cancer Inst (1991) 1.72
Mechanisms of disease: adipokines and breast cancer - endocrine and paracrine mechanisms that connect adiposity and breast cancer. Nat Clin Pract Endocrinol Metab (2007) 1.56
Dietary fat and risk of postmenopausal breast cancer in a 20-year follow-up. Am J Epidemiol (2006) 1.55
Types of dietary fat and breast cancer: a pooled analysis of cohort studies. Int J Cancer (2001) 1.48
The underlying basis for obesity: relationship to cancer. J Nutr (2002) 1.42
Premenopausal fat intake and risk of breast cancer. J Natl Cancer Inst (2003) 1.41
Western diet, early puberty, and breast cancer risk. Breast Cancer Res Treat (1998) 1.26
Energy balance and carcinogenesis: underlying pathways and targets for intervention. Curr Cancer Drug Targets (2007) 1.26
A nonparametric bootstrap method for testing close linkage vs. pleiotropy of coincident quantitative trait loci. Genetics (1998) 1.21
Dietary factors and endometrial cancer risk. Results of a case-control study in Mexico. Int J Gynecol Cancer (2005) 1.19
Insulin and cancer. Integr Cancer Ther (2003) 1.16
Dietary fibre and risk of breast cancer in the UK Women's Cohort Study. Int J Epidemiol (2007) 1.14
Modifiers of mammary tumor progression and metastasis on mouse chromosomes 7, 9, and 17. Mamm Genome (2005) 1.10
Genomic mapping of direct and correlated responses to long-term selection for rapid growth rate in mice. Genetics (2005) 1.08
The prevalence of BRCA1 and BRCA2 mutations in eastern Chinese women with breast cancer. J Cancer Res Clin Oncol (2006) 1.00
An epistatic interaction controls the latency of a transgene-induced mammary tumor. Mamm Genome (2000) 0.99
Breast cancer and dietary factors in Taiwanese women. Cancer Causes Control (2005) 0.98
Dietary fat and carbohydrates are independently associated with circulating insulin-like growth factor 1 and insulin-like growth factor-binding protein 3 concentrations in healthy adults. J Clin Oncol (1999) 0.93
Dietary intakes of fat and fatty acids and risk of breast cancer: a prospective study in Japan. Cancer Sci (2005) 0.93
Dietary effects of fatty acids on growth and metastasis of KPL-1 human breast cancer cells in vivo and in vitro. Anticancer Res (1998) 0.91
Genotype X diet interactions in mice predisposed to mammary cancer. I. Body weight and fat. Mamm Genome (2008) 0.89
p53 Alterations and protein accumulation in benign breast tissue and breast cancer risk: a cohort study. Cancer Epidemiol Biomarkers Prev (2006) 0.86
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat Genet (2005) 10.03
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors. Proc Natl Acad Sci U S A (2010) 6.10
Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behav Brain Res (2006) 4.15
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome (2008) 3.52
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell (2012) 3.19
Bayesian model selection for genome-wide epistatic quantitative trait loci analysis. Genetics (2005) 3.10
Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort. Mamm Genome (2002) 3.02
Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Nat Genet (2005) 2.92
The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics. Mamm Genome (2007) 2.82
Methods for interpreting lists of affected genes obtained in a DNA microarray experiment. BMC Proc (2009) 2.80
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol (2007) 2.70
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc Natl Acad Sci U S A (2002) 2.65
Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15. Genomics (2004) 2.59
Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behavior. Clin Exp Metastasis (2005) 2.52
Collateral density, remodeling, and VEGF-A expression differ widely between mouse strains. Physiol Genomics (2007) 2.46
Bromodomain 4 activation predicts breast cancer survival. Proc Natl Acad Sci U S A (2008) 2.15
Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation. Mol Cell Biol (2006) 2.12
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor. Cancer Res (2005) 1.94
Strain screen and haplotype association mapping of wheel running in inbred mouse strains. J Appl Physiol (1985) (2010) 1.88
An efficient Bayesian model selection approach for interacting quantitative trait loci models with many effects. Genetics (2007) 1.82
Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer. Breast Cancer Res (2006) 1.81
Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations. Genetics (2005) 1.80
Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease. Genome Biol (2009) 1.77
Genetics of dark skin in mice. Genes Dev (2003) 1.68
Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival. Gastroenterology (2011) 1.68
EGFR signaling promotes TGFβ-dependent renal fibrosis. J Am Soc Nephrol (2011) 1.64
Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice. Environ Health Perspect (2010) 1.60
Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. Genome Res (2009) 1.60
Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease. Cancer Res (2004) 1.57
Pleiotropy of quantitative trait loci for organ weights and limb bone lengths in mice. Physiol Genomics (2002) 1.57
The EGFR is required for proper innervation to the skin. J Invest Dermatol (2008) 1.55
Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis. PLoS Genet (2007) 1.55
Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy. Am J Physiol Heart Circ Physiol (2006) 1.52
A high-resolution multistrain haplotype analysis of laboratory mouse genome reveals three distinctive genetic variation patterns. Genome Res (2005) 1.50
Ten years of the collaborative cross. G3 (Bethesda) (2012) 1.50
Phosphatidylinositol 3-kinase signaling determines kidney size. J Clin Invest (2015) 1.46
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis. Nat Med (2011) 1.46
Quantitative trait loci for physical activity traits in mice. Physiol Genomics (2008) 1.45
Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment. Mamm Genome (2006) 1.44
A large-sample QTL study in mice: I. Growth. Mamm Genome (2004) 1.43
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog (2013) 1.43
Metastasis predictive signature profiles pre-exist in normal tissues. Clin Exp Metastasis (2006) 1.43
Multiple cross and inbred strain haplotype mapping of complex-trait candidate genes. Genome Res (2003) 1.41
Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice. Bone (2013) 1.40
Genome-wide analysis on inbreeding effects on gene expression in Drosophila melanogaster. Genetics (2005) 1.39
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation. J Exp Med (2012) 1.39
Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype. Genetics (2006) 1.37
The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival. Clin Exp Metastasis (2008) 1.36
Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor. Genesis (2009) 1.36
Genetic analysis of hematological parameters in incipient lines of the collaborative cross. G3 (Bethesda) (2012) 1.35
Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice. G3 (Bethesda) (2012) 1.35
Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene. Cancer Res (2005) 1.34
Status and access to the Collaborative Cross population. Mamm Genome (2012) 1.32
Modeling metastasis biology and therapy in real time in the mouse lung. J Clin Invest (2010) 1.32
A large-sample QTL study in mice: II. Body composition. Mamm Genome (2004) 1.31
Genetic architecture of voluntary exercise in an advanced intercross line of mice. Physiol Genomics (2010) 1.30
Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology (2007) 1.29
Cadm1 is a metastasis susceptibility gene that suppresses metastasis by modifying tumor interaction with the cell-mediated immunity. PLoS Genet (2012) 1.27
Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage. Mol Cell Biol (2004) 1.26
Bayesian analyses of multiple epistatic QTL models for body weight and body composition in mice. Genet Res (2006) 1.24
Inbreeding by environmental interactions affect gene expression in Drosophila melanogaster. Genetics (2006) 1.23
Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models. Clin Cancer Res (2007) 1.22
The occurrence of hyponatremia in SCLC and the influence on prognosis: a retrospective study of 453 patients treated in a single institution in a 10-year period. Lung Cancer (2009) 1.21
Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: effects of dose, route, and diet. Toxicol Sci (2005) 1.21
Architecture of energy balance traits in emerging lines of the Collaborative Cross. Am J Physiol Endocrinol Metab (2011) 1.20
Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium. J Clin Invest (2009) 1.20
Fine mapping of a QTL region with large effects on growth and fatness on mouse chromosome 2. Physiol Genomics (2005) 1.19
Distinct inherited metastasis susceptibility exists for different breast cancer subtypes: a prognosis study. Breast Cancer Res (2009) 1.19
An epistatic genetic basis for physical activity traits in mice. J Hered (2008) 1.19
Bayesian mapping of genomewide interacting quantitative trait loci for ordinal traits. Genetics (2007) 1.17
Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor. Mamm Genome (2004) 1.16
Deletion of the proline-rich region of the murine metastasis susceptibility gene Brd4 promotes epithelial-to-mesenchymal transition- and stem cell-like conversion. Cancer Res (2011) 1.16
Dopaminergic dysregulation in mice selectively bred for excessive exercise or obesity. Behav Brain Res (2010) 1.14
QTL underlying voluntary exercise in mice: interactions with the "mini muscle" locus and sex. J Hered (2009) 1.12
Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. Toxicol Sci (2009) 1.11
Host genetics and diet, but not immunoglobulin A expression, converge to shape compositional features of the gut microbiome in an advanced intercross population of mice. Genome Biol (2014) 1.10
Bayesian multiple quantitative trait loci mapping for complex traits using markers of the entire genome. Genetics (2007) 1.10
Modifiers of mammary tumor progression and metastasis on mouse chromosomes 7, 9, and 17. Mamm Genome (2005) 1.10
The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice. Evol Dev (2006) 1.10
Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. Genes Dev (2009) 1.10
A large-sample QTL study in mice: III. Reproduction. Mamm Genome (2004) 1.08
Genomic mapping of direct and correlated responses to long-term selection for rapid growth rate in mice. Genetics (2005) 1.08
In depth analysis of genes and pathways of the mammary gland involved in the pathogenesis of bovine Escherichia coli-mastitis. BMC Genomics (2011) 1.06
Importance of randomization in microarray experimental designs with Illumina platforms. Nucleic Acids Res (2009) 1.06
Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage. Cancer Res (2007) 1.05
Genetic variation in the pleiotropic association between physical activity and body weight in mice. Genet Sel Evol (2009) 1.05
Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK. J Clin Invest (2013) 1.03
Murine models of colorectal cancer. Mamm Genome (2009) 1.03
Integrated cross-species transcriptional network analysis of metastatic susceptibility. Proc Natl Acad Sci U S A (2012) 1.03
Toxicogenetics: population-based testing of drug and chemical safety in mouse models. Pharmacogenomics (2010) 1.02
The origins of breast cancer prognostic gene expression profiles. Cancer Res (2009) 1.02
Parent-of-origin effects on voluntary exercise levels and body composition in mice. Physiol Genomics (2009) 1.02
A bioinformatics-based strategy identifies c-Myc and Cdc25A as candidates for the Apmt mammary tumor latency modifiers. Genome Res (2002) 1.01
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors. Toxicol Sci (2010) 1.00
Flies selected for longevity retain a young gene expression profile. Age (Dordr) (2010) 1.00