Published in Cancer Res on December 15, 2007
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med (2010) 4.37
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity (2012) 2.07
Pathology of rodent models of intestinal cancer: progress report and recommendations. Gastroenterology (2013) 1.12
Murine models of colorectal cancer. Mamm Genome (2009) 1.03
Epidermal growth factor receptor inhibits colitis-associated cancer in mice. J Clin Invest (2012) 1.01
Longitudinal assessment of colonic tumor fate in mice by computed tomography and optical colonoscopy. Acad Radiol (2009) 0.96
Colon cancer and the elderly: from screening to treatment in management of GI disease in the elderly. Best Pract Res Clin Gastroenterol (2009) 0.87
Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors. BMC Cancer (2013) 0.86
Putative precursor cancer cells in human colorectal cancer tissue. Int J Clin Exp Pathol (2008) 0.81
Mapping six new susceptibility to colon cancer (Scc) loci using a mouse interspecific backcross. G3 (Bethesda) (2012) 0.80
Differential response of flat and polypoid colitis-associated colorectal neoplasias to chemopreventive agents and heterocyclic amines. Cancer Lett (2013) 0.77
Effects of 5-Amyno-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one Intake on Digestive System in a Rat Model of Colon Cancer. ScientificWorldJournal (2015) 0.75
Ex Vivo and In Vivo Noninvasive Imaging of Epidermal Growth Factor Receptor Inhibition on Colon Tumorigenesis Using Activatable Near-Infrared Fluorescent Probes. Mol Imaging (2017) 0.75
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat Genet (2005) 10.03
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med (2010) 4.37
Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behav Brain Res (2006) 4.15
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Esophageal dilation in eosinophilic esophagitis: safety and predictors of clinical response and complications. Gastrointest Endosc (2010) 3.74
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome (2008) 3.52
EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell (2012) 3.19
The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics. Mamm Genome (2007) 2.82
Increased risk for non-melanoma skin cancer in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol (2010) 2.80
Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility. PLoS One (2009) 2.79
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol (2007) 2.70
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc Natl Acad Sci U S A (2002) 2.65
Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15. Genomics (2004) 2.59
Clinical, endoscopic, and histologic findings distinguish eosinophilic esophagitis from gastroesophageal reflux disease. Clin Gastroenterol Hepatol (2009) 2.53
Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation. Mol Cell Biol (2006) 2.12
Conjugated linoleic acid modulates immune responses in patients with mild to moderately active Crohn's disease. Clin Nutr (2012) 2.11
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity (2012) 2.07
Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease. Gastroenterology (2012) 1.97
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor. Cancer Res (2005) 1.94
Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations. Genetics (2005) 1.80
Inter- and intraobserver reliability and validation of a new method for determination of eosinophil counts in patients with esophageal eosinophilia. Dig Dis Sci (2009) 1.70
Genetics of dark skin in mice. Genes Dev (2003) 1.68
Reduced polyp detection as endoscopy shift progresses: experience with screening colonoscopy at a tertiary-care hospital. J Clin Gastroenterol (2011) 1.66
EGFR signaling promotes TGFβ-dependent renal fibrosis. J Am Soc Nephrol (2011) 1.64
Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice. Environ Health Perspect (2010) 1.60
Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. Genome Res (2009) 1.60
The EGFR is required for proper innervation to the skin. J Invest Dermatol (2008) 1.55
Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy. Am J Physiol Heart Circ Physiol (2006) 1.52
Ten years of the collaborative cross. G3 (Bethesda) (2012) 1.50
Phosphatidylinositol 3-kinase signaling determines kidney size. J Clin Invest (2015) 1.46
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis. Nat Med (2011) 1.46
Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment. Mamm Genome (2006) 1.44
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog (2013) 1.43
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation. J Exp Med (2012) 1.39
Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype. Genetics (2006) 1.37
Tryptase staining of mast cells may differentiate eosinophilic esophagitis from gastroesophageal reflux disease. Am J Gastroenterol (2010) 1.37
Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor. Genesis (2009) 1.36
Genetic analysis of hematological parameters in incipient lines of the collaborative cross. G3 (Bethesda) (2012) 1.35
Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice. G3 (Bethesda) (2012) 1.35
Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene. Cancer Res (2005) 1.34
Status and access to the Collaborative Cross population. Mamm Genome (2012) 1.32
Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology (2007) 1.29
Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage. Mol Cell Biol (2004) 1.26
Lactobacillus GG in inducing and maintaining remission of Crohn's disease. BMC Gastroenterol (2004) 1.23
Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: effects of dose, route, and diet. Toxicol Sci (2005) 1.21
Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium. J Clin Invest (2009) 1.20
Architecture of energy balance traits in emerging lines of the Collaborative Cross. Am J Physiol Endocrinol Metab (2011) 1.20
Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor. Mamm Genome (2004) 1.16
Prevalence and epidemiology of overweight and obesity in children with inflammatory bowel disease. Inflamm Bowel Dis (2010) 1.13
Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. Toxicol Sci (2009) 1.11
Bayesian multiple quantitative trait loci mapping for complex traits using markers of the entire genome. Genetics (2007) 1.10
Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. Genes Dev (2009) 1.10
Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice. PLoS One (2009) 1.07
Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK. J Clin Invest (2013) 1.03
Murine models of colorectal cancer. Mamm Genome (2009) 1.03
Toxicogenetics: population-based testing of drug and chemical safety in mouse models. Pharmacogenomics (2010) 1.02
Gnotobiotic IL-10; NF-kappaB mice develop rapid and severe colitis following Campylobacter jejuni infection. PLoS One (2009) 1.02
MicroRNAs Classify Different Disease Behavior Phenotypes of Crohn's Disease and May Have Prognostic Utility. Inflamm Bowel Dis (2015) 1.00
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors. Toxicol Sci (2010) 1.00
Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice. Toxicol Sci (2010) 0.99
Modeling the cancer patient with genetically engineered mice: prediction of toxicity from molecule-targeted therapies. Cancer Cell (2004) 0.99
Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice. Am J Physiol Heart Circ Physiol (2009) 0.99
Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo. J Bone Miner Res (2011) 0.97
Development of communicating hydrocephalus after infliximab infusion. Inflamm Bowel Dis (2011) 0.97
Challenges in IBD research: update on progress and prioritization of the CCFA's research agenda. Inflamm Bowel Dis (2013) 0.97
Impact of capsule endoscopy on management of inflammatory bowel disease: a single tertiary care center experience. Inflamm Bowel Dis (2011) 0.96
The gastrointestinal microbiome: a malleable, third genome of mammals. Mamm Genome (2009) 0.95
Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice. Toxicol Appl Pharmacol (2008) 0.95
Multifocal gastrointestinal stromal tumor (GIST) of the stomach in an 11-year-old girl. Pediatr Radiol (2006) 0.95
Targeted inactivation of EGF receptor inhibits renal collecting duct development and function. J Am Soc Nephrol (2010) 0.94
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy. BMC Genomics (2014) 0.94
Comparison of interobserver agreement for different scoring systems for reflux esophagitis: Impact of level of experience. Gastrointest Endosc (2004) 0.93
Replication and narrowing of gene expression quantitative trait loci using inbred mice. Mamm Genome (2009) 0.92
Evaluation of a non-invasive method to detect cytomegalovirus (CMV)-DNA in stool samples of patients with inflammatory bowel disease (IBD): a pilot study. Dig Dis Sci (2010) 0.91
Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice. Mamm Genome (2011) 0.89
Narcotic use for inflammatory bowel disease and risk factors during hospitalization. Inflamm Bowel Dis (2011) 0.88
Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression. Clin Exp Metastasis (2010) 0.88
Modeling cancer patient populations in mice: complex genetic and environmental factors. Drug Discov Today Dis Models (2008) 0.87
Genotype X diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis. Mamm Genome (2008) 0.87
Enhanced oligonucleotide microarray labeling and hybridization. Biotechniques (2006) 0.86
Animal models of autism spectrum disorders: information for neurotoxicologists. Neurotoxicology (2009) 0.86
Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross. BMC Genet (2010) 0.86
Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles. Genetics (2009) 0.86
The inflammatory bowel disease live interinstitutional and interdisciplinary videoconference education (IBD LIVE) series. Inflamm Bowel Dis (2014) 0.86
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. Exp Cell Res (2009) 0.86
Human epithelial-specific response to pathogenic Campylobacter jejuni. FEMS Microbiol Lett (2006) 0.85
Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia. J Neurodev Disord (2009) 0.85
Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis. Clin Exp Metastasis (2010) 0.85
Metastatic potential as a heritable trait. Nat Genet (2005) 0.84
Parent-of-origin effects on cardiac response to pressure overload in mice. Am J Physiol Heart Circ Physiol (2009) 0.84
Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response. J Natl Cancer Inst (2013) 0.84
Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors. Environ Health Perspect (2009) 0.84
MicroRNA expression in the livers of inbred mice. Mutat Res (2011) 0.83
Down's syndrome: paradox of a tumour repressor. Nature (2008) 0.83
Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice. Am J Physiol Gastrointest Liver Physiol (2014) 0.83