Published in Crit Care Med on April 01, 2008
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet) | NCT00000579
Neuromuscular Blockade in the Intentive Care Unit, an Observational Study. (CURATIV) | NCT04028362
Long-term cognitive and psychological outcomes in the awakening and breathing controlled trial. Am J Respir Crit Care Med (2010) 1.70
Diurnal sedative changes during intensive care: impact on liberation from mechanical ventilation and delirium. Crit Care Med (2012) 1.59
Early sedation and clinical outcomes of mechanically ventilated patients: a prospective multicenter cohort study. Crit Care (2014) 1.44
Severe hypoxemia: which strategy to choose. Crit Care (2016) 0.82
Conservative fluid therapy in septic shock: an example of targeted therapeutic minimization. Crit Care (2014) 0.79
Role of sedation and analgesia in mechanical ventilation. Crit Care Med (2008) 0.78
A fresh look at paralytics in the critically ill: real promise and real concern. Ann Intensive Care (2012) 0.78
Does music influence stress in mechanically ventilated patients? Intensive Crit Care Nurs (2012) 0.78
Pharmacological interventions in acute respiratory distress syndrome. Ann Intensive Care (2013) 0.77
Music preferences of mechanically ventilated patients participating in a randomized controlled trial. Music Med (2014) 0.75
A ventilator strategy combining low tidal volume ventilation, recruitment maneuvers, and high positive end-expiratory pressure does not increase sedative, opioid, or neuromuscular blocker use in adults with acute respiratory distress syndrome and may improve patient comfort. Ann Intensive Care (2014) 0.75
Physical therapy management of ventilated patients with acute respiratory distress syndrome or severe acute lung injury. Physiother Can (2011) 0.75
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2007) 47.86
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57
Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis (2007) 24.91
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2012) 22.96
Acute respiratory distress syndrome: the Berlin Definition. JAMA (2012) 21.04
Comparison of two fluid-management strategies in acute lung injury. N Engl J Med (2006) 19.54
Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med (2010) 15.07
Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med (2008) 14.40
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell (2007) 12.52
Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med (2004) 11.78
International study of the prevalence and outcomes of infection in intensive care units. JAMA (2009) 11.57
Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med (2006) 9.52
Drotrecogin alfa (activated) in adults with septic shock. N Engl J Med (2012) 9.19
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury. N Engl J Med (2006) 7.97
Noninvasive positive-pressure ventilation for respiratory failure after extubation. N Engl J Med (2004) 7.03
Tiotropium Respimat inhaler and the risk of death in COPD. N Engl J Med (2013) 6.36
Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. JAMA (2002) 6.00
Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med (2005) 5.76
Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial. JAMA (2012) 5.27
Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med (2011) 5.24
Clinical predictors of and mortality in acute respiratory distress syndrome: potential role of red cell transfusion. Crit Care Med (2005) 5.16
Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. JAMA (2011) 5.08
Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA (2012) 4.67
Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J Clin Oncol (2009) 4.54
Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit Care Med (2004) 4.24
Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock. Intensive Care Med (2008) 4.21
GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. Lancet Respir Med (2012) 3.98
Partial liquid ventilation in adult patients with acute respiratory distress syndrome. Am J Respir Crit Care Med (2005) 3.75
The role of open-lung biopsy in ARDS. Chest (2004) 3.46
Evolution of mechanical ventilation in response to clinical research. Am J Respir Crit Care Med (2007) 3.45
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. J Clin Oncol (2010) 3.43
Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. J Clin Oncol (2009) 3.39
Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med (2014) 3.39
Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. J Am Soc Nephrol (2005) 3.38
Ventilator settings as a risk factor for acute respiratory distress syndrome in mechanically ventilated patients. Intensive Care Med (2005) 3.32
Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome. Crit Care Med (2007) 3.31
Randomized clinical trial of activated protein C for the treatment of acute lung injury. Am J Respir Crit Care Med (2008) 3.28
Relative biological effectiveness (RBE) values for proton beam therapy. Int J Radiat Oncol Biol Phys (2002) 3.21
Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study. Am J Respir Crit Care Med (2010) 3.21
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med (2012) 3.18
Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping. Oncologist (2011) 3.05
Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial. JAMA (2008) 3.01
A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients. Cancer Res (2009) 3.00
Challenges in end-of-life care in the ICU: statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003: executive summary. Crit Care Med (2004) 2.95
Evolution of mortality over time in patients receiving mechanical ventilation. Am J Respir Crit Care Med (2013) 2.95
Excess body weight is not independently associated with outcome in mechanically ventilated patients with acute lung injury. Ann Intern Med (2004) 2.80
Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med (2007) 2.79
The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury. Am J Respir Crit Care Med (2012) 2.72
Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. Am J Respir Crit Care Med (2006) 2.61
Risk factors for extubation failure in patients following a successful spontaneous breathing trial. Chest (2006) 2.60
Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med (2001) 2.57
Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med (2011) 2.55
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proc Natl Acad Sci U S A (2012) 2.50
Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury. Am J Respir Crit Care Med (2004) 2.49
Plasma surfactant protein levels and clinical outcomes in patients with acute lung injury. Thorax (2003) 2.47
Vitamin D reduces left atrial volume in patients with left ventricular hypertrophy and chronic kidney disease. Am Heart J (2012) 2.42
Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion. Cancer Res (2011) 2.40
Relationship of continuous infusion lorazepam to serum propylene glycol concentration in critically ill adults. Crit Care Med (2004) 2.40
A protocol for high-frequency oscillatory ventilation in adults: results from a roundtable discussion. Crit Care Med (2007) 2.38
Comparison of two guideline-concordant antimicrobial combinations in elderly patients hospitalized with severe community-acquired pneumonia. Crit Care Med (2012) 2.38
Airway pressures, tidal volumes, and mortality in patients with acute respiratory distress syndrome. Crit Care Med (2005) 2.37
Polymorphisms in the mannose binding lectin-2 gene and acute respiratory distress syndrome. Crit Care Med (2007) 2.31
Observational study of inhaled corticosteroids on outcomes for COPD patients with pneumonia. Am J Respir Crit Care Med (2011) 2.30
Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med (2010) 2.28
Preoperative and intraoperative predictors of postoperative acute respiratory distress syndrome in a general surgical population. Anesthesiology (2013) 2.22
Barriers to providing lung-protective ventilation to patients with acute lung injury. Crit Care Med (2004) 2.20
The effect of prior statin use on 30-day mortality for patients hospitalized with community-acquired pneumonia. Respir Res (2005) 2.18
Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest (2009) 2.17
Characteristics and outcomes of ventilated patients according to time to liberation from mechanical ventilation. Am J Respir Crit Care Med (2011) 2.15
Racial and ethnic disparities in mortality from acute lung injury. Crit Care Med (2009) 2.14
A comparative study of community-acquired pneumonia patients admitted to the ward and the ICU. Chest (2007) 2.14
Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation. Proc Natl Acad Sci U S A (2013) 2.14
Point: Efficacy of extracorporeal membrane oxygenation in 2009 influenza A(H1N1): sufficient evidence? Chest (2010) 2.13
Impact of sedation and analgesia during noninvasive positive pressure ventilation on outcome: a marginal structural model causal analysis. Intensive Care Med (2015) 2.11
Pre-B-cell colony-enhancing factor gene polymorphisms and risk of acute respiratory distress syndrome. Crit Care Med (2007) 2.08
Systematic review of the chronic care model in chronic obstructive pulmonary disease prevention and management. Arch Intern Med (2007) 2.06
Accelerated partial breast irradiation with low-dose-rate interstitial implant brachytherapy after wide local excision: 12-year outcomes from a prospective trial. Int J Radiat Oncol Biol Phys (2011) 2.06
Outcomes of patients ventilated with synchronized intermittent mandatory ventilation with pressure support: a comparative propensity score study. Chest (2009) 2.03
Macrolide antibiotics for prevention of chronic obstructive pulmonary disease exacerbations: are we there yet? Am J Respir Crit Care Med (2014) 2.00
Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States. Crit Care Med (2012) 2.00
Early thickening of the reticular basement membrane in children with difficult asthma. Am J Respir Crit Care Med (2003) 1.94
Utility of B-type natriuretic peptide for the evaluation of intensive care unit shock. Crit Care Med (2004) 1.92
Outcome of mechanically ventilated patients who require a tracheostomy. Crit Care Med (2005) 1.91
A simple clinical predictive index for objective estimates of mortality in acute lung injury. Crit Care Med (2009) 1.91
Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology. Clin J Am Soc Nephrol (2012) 1.90
Effect of fluticasone propionate/salmeterol (250/50 microg) or salmeterol (50 microg) on COPD exacerbations. Respir Med (2008) 1.89
Heme oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome. Intensive Care Med (2009) 1.87
Impact of statins and ACE inhibitors on mortality after COPD exacerbations. Respir Res (2009) 1.85