Published in BMC Genomics on April 16, 2008
An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data. PLoS Comput Biol (2009) 7.47
Tissue specificity and the human protein interaction network. Mol Syst Biol (2009) 3.20
Identification and validation of reference genes for quantitative RT-PCR normalization in wheat. BMC Mol Biol (2009) 3.04
Evaluation of putative reference genes for gene expression normalization in soybean by quantitative real-time RT-PCR. BMC Mol Biol (2009) 2.34
A comprehensive functional analysis of tissue specificity of human gene expression. BMC Biol (2008) 2.15
Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression. Genes Dev (2013) 1.74
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Definition, conservation and epigenetics of housekeeping and tissue-enriched genes. BMC Genomics (2009) 1.30
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Genomic selection of reference genes for real-time PCR in human myocardium. BMC Med Genomics (2008) 1.19
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The transcript-centric mutations in human genomes. Genomics Proteomics Bioinformatics (2012) 0.95
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Human functional genetic studies are biased against the medically most relevant primate-specific genes. BMC Evol Biol (2010) 0.90
Substantial DNA methylation differences between two major neuronal subtypes in human brain. Nucleic Acids Res (2015) 0.90
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Validation and Comparison of Reference Genes for qPCR Normalization of Celery (Apium graveolens) at Different Development Stages. Front Plant Sci (2016) 0.89
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Improvement of genome assembly completeness and identification of novel full-length protein-coding genes by RNA-seq in the giant panda genome. Sci Rep (2015) 0.78
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Optimal scaling of digital transcriptomes. PLoS One (2013) 0.77
Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response. PLoS Comput Biol (2015) 0.77
Evaluation of Reference Genes for Reverse Transcription Quantitative PCR Studies of Physiological Responses in the Ghost Moth, Thitarodes armoricanus (Lepidoptera, Hepialidae). PLoS One (2016) 0.76
Conserved and divergent patterns of DNA methylation in higher vertebrates. Genome Biol Evol (2014) 0.76
Comparative Validation of Conventional and RNA-Seq Data-Derived Reference Genes for qPCR Expression Studies of Colletotrichum kahawae. PLoS One (2016) 0.75
Quantitative proteogenomic profiling of epidermal barrier formation in vitro. J Dermatol Sci (2015) 0.75
Identifying reproducible cancer-associated highly expressed genes with important functional significances using multiple datasets. Sci Rep (2016) 0.75
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Detection bias in microarray and sequencing transcriptomic analysis identified by housekeeping genes. Data Brief (2015) 0.75
Selection and Validation of Reference Genes for Gene Expression Analysis in Vigna angularis Using Quantitative Real-Time RT-PCR. PLoS One (2016) 0.75
The Sporothrix schenckii Gene Encoding for the Ribosomal Protein L6 Has Constitutive and Stable Expression and Works as an Endogenous Control in Gene Expression Analysis. Front Microbiol (2017) 0.75
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Comprehensive proteomic analysis of the human spliceosome. Nature (2002) 6.85
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Dynamic nuclear pore complexes: life on the edge. Cell (2006) 4.53
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Control genes and variability: absence of ubiquitous reference transcripts in diverse mammalian expression studies. Genome Res (2002) 4.49
New perspectives on connecting messenger RNA 3' end formation to transcription. Curr Opin Cell Biol (2004) 4.04
A conserved mRNA export machinery coupled to pre-mRNA splicing. Cell (2002) 3.88
Tag-based approaches for transcriptome research and genome annotation. Nat Methods (2005) 3.52
GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues. Physiol Genomics (2005) 3.33
Mammalian housekeeping genes evolve more slowly than tissue-specific genes. Mol Biol Evol (2003) 3.33
The ends of the affair: capping and polyadenylation. Nat Struct Biol (2000) 3.31
The cancer genome anatomy project: building an annotated gene index. Trends Genet (2000) 3.02
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Tagging mammalian transcription complexity. Trends Genet (2006) 2.27
The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. Genome Res (2002) 2.03
Isochores and tissue-specificity. Nucleic Acids Res (2003) 2.00
Further defining housekeeping, or "maintenance," genes Focus on "A compendium of gene expression in normal human tissues". Physiol Genomics (2001) 1.85
Modularity within the architecture of the nuclear pore complex. Curr Opin Struct Biol (2005) 1.80
Compactness of human housekeeping genes: selection for economy or genomic design? Trends Genet (2004) 1.79
Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the proteins. Genome Biol (2005) 1.33
Mining housekeeping genes with a Naive Bayes classifier. BMC Genomics (2006) 1.22
Protein domains enriched in mammalian tissue-specific or widely expressed genes. Trends Genet (2004) 1.21
Housekeeping genes tend to show reduced upstream sequence conservation. Genome Biol (2007) 1.16
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes. BMC Bioinformatics (2005) 1.13
Repetitive sequence environment distinguishes housekeeping genes. Gene (2006) 1.12
Modeling transcriptome based on transcript-sampling data. PLoS One (2008) 0.96
Interrogating the transcriptome. Trends Biotechnol (2004) 0.92
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
International network of cancer genome projects. Nature (2010) 20.35
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
WEGO: a web tool for plotting GO annotations. Nucleic Acids Res (2006) 13.06
Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Nat Genet (2007) 12.62
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Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature (2006) 11.90
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science (2011) 11.12
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol (2008) 10.42
MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell (2007) 9.33
Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial. Lancet (2008) 9.17
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol (2010) 9.01
Changes in diabetes-related complications in the United States, 1990-2010. N Engl J Med (2014) 8.73
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
Self-monitoring in weight loss: a systematic review of the literature. J Am Diet Assoc (2011) 5.12
Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res (2002) 4.92
VFDB: a reference database for bacterial virulence factors. Nucleic Acids Res (2005) 4.77
AlleleSeq: analysis of allele-specific expression and binding in a network framework. Mol Syst Biol (2011) 4.71
The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science (2009) 4.63
RePS: a sequence assembler that masks exact repeats identified from the shotgun data. Genome Res (2002) 4.35
KaKs_Calculator: calculating Ka and Ks through model selection and model averaging. Genomics Proteomics Bioinformatics (2006) 4.15
Priming of naive T cells inside tumors leads to eradication of established tumors. Nat Immunol (2004) 3.95
Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. J Clin Invest (2005) 3.95
Glycolytic enzymes can modulate cellular life span. Cancer Res (2005) 3.78
Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell (2003) 3.75
Large-gap quantum spin Hall insulators in tin films. Phys Rev Lett (2013) 3.60
Regulation of OsSPL14 by OsmiR156 defines ideal plant architecture in rice. Nat Genet (2010) 3.56
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res (2005) 3.56
An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res (2012) 3.48
Tissue-specific contributions of pneumococcal virulence factors to pathogenesis. J Infect Dis (2004) 3.43
ATM mutations in patients with hereditary pancreatic cancer. Cancer Discov (2011) 3.27
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature (2012) 3.23
Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe. Nat Genet (2012) 3.22
Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection. N Engl J Med (2015) 3.13
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature (2010) 3.09
VFDB 2008 release: an enhanced web-based resource for comparative pathogenomics. Nucleic Acids Res (2007) 3.07
HIV/STD risk behaviors and perceptions among rural-to-urban migrants in China. AIDS Educ Prev (2004) 3.04
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proc Natl Acad Sci U S A (2008) 3.03
Mouse transcriptome: neutral evolution of 'non-coding' complementary DNAs. Nature (2004) 3.00
Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans. DNA Res (2004) 2.95
Ten-eleven translocation-2 (TET2) is a master regulator of smooth muscle cell plasticity. Circulation (2013) 2.95
Evolution of the immunoglobulin heavy chain class switch recombination mechanism. Adv Immunol (2007) 2.94
The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1. Cell Metab (2008) 2.84
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Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. J Natl Cancer Inst (2012) 2.79
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MicroRNA array analysis finds elevated serum miR-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls. Clin Cancer Res (2013) 2.71
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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1. Cancer Discov (2012) 2.68
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A developmental approach to complex PTSD: childhood and adult cumulative trauma as predictors of symptom complexity. J Trauma Stress (2009) 2.59
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PDGF signalling controls age-dependent proliferation in pancreatic β-cells. Nature (2011) 2.53
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SilkDB: a knowledgebase for silkworm biology and genomics. Nucleic Acids Res (2005) 2.50
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Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. Cancer Discov (2013) 2.49
PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B. Cell (2008) 2.49
A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates. PLoS One (2007) 2.47
Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis (2009) 2.45
MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance. Mol Cancer Ther (2009) 2.41
Microarrays: retracing steps. Nat Med (2007) 2.39
Direct continuous method for monitoring biofilm infection in a mouse model. Infect Immun (2003) 2.35
Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing. BMC Genomics (2005) 2.34
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BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways. Proc Natl Acad Sci U S A (2004) 2.25
Crash and risky driving involvement among novice adolescent drivers and their parents. Am J Public Health (2011) 2.25
Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis. Proc Natl Acad Sci U S A (2012) 2.22
The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen. Nucleic Acids Res (2005) 2.21
The completion of the Mammalian Gene Collection (MGC). Genome Res (2009) 2.21
Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S. J Neurosci (2010) 2.20
Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins. Genomics (2002) 2.16
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Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research. Nucleic Acids Res (2006) 2.14
Vertebrate gene predictions and the problem of large genes. Nat Rev Genet (2003) 2.11
Proteomic markers of DNA repair and PI3K pathway activation predict response to the PARP inhibitor BMN 673 in small cell lung cancer. Clin Cancer Res (2013) 2.09
Increased expression of CYP17 and CYP11B1 in subclinical Cushing's syndrome due to adrenal adenomas. Int J Urol (2011) 2.07
On the nature of human housekeeping genes. Trends Genet (2008) 2.06
Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain. J Neurosci (2012) 2.06
T1rho MR imaging is sensitive to evaluate liver fibrosis: an experimental study in a rat biliary duct ligation model. Radiology (2011) 2.05
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Compositional gradients in Gramineae genes. Genome Res (2002) 2.04