Published in Cardiovasc Res on April 30, 2008
Alcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial-mesenchymal transition in colon and breast cancer cells. Alcohol Clin Exp Res (2009) 1.09
Molecular pathways of notch signaling in vascular smooth muscle cells. Front Physiol (2012) 1.07
Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts. PLoS One (2012) 1.06
Alcohol inhibits smooth muscle cell proliferation via regulation of the Notch signaling pathway. Arterioscler Thromb Vasc Biol (2010) 0.92
Clinical and genetic correlates of circulating angiopoietin-2 and soluble Tie-2 in the community. Circ Cardiovasc Genet (2010) 0.89
Pitavastatin-induced angiogenesis and arteriogenesis is mediated by Notch1 in a murine hindlimb ischemia model without induction of VEGF. Lab Invest (2011) 0.87
Alcohol and cardiovascular disease--modulation of vascular cell function. Nutrients (2012) 0.87
Molecular mechanisms of ethanol-associated oro-esophageal squamous cell carcinoma. Cancer Lett (2015) 0.84
Effects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes. BMC Dev Biol (2010) 0.82
Toxic damage increases angiogenesis and metastasis in fibrotic livers via PECAM-1. Biomed Res Int (2014) 0.79
Notch pathway activation contributes to inhibition of C2C12 myoblast differentiation by ethanol. PLoS One (2013) 0.78
Ethanol Inhibits γ-Secretase Proteolytic Activity in Vascular Smooth Muscle Cells. Alcohol Clin Exp Res (2015) 0.77
Flk-1/KDR mediates ethanol-stimulated endothelial cell Notch signaling and angiogenic activity. J Vasc Res (2014) 0.77
Alcohol Disrupts Human Liver Stem/Progenitor Cell Proliferation and Differentiation. J Stem Cell Res Ther (2014) 0.75
Notch signaling: cell fate control and signal integration in development. Science (1999) 28.83
Angiogenesis in life, disease and medicine. Nature (2005) 15.36
Alcohol consumption and mortality among middle-aged and elderly U.S. adults. N Engl J Med (1997) 8.25
HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol (2003) 7.32
Notch signaling is essential for vascular morphogenesis in mice. Genes Dev (2000) 6.88
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature (2006) 6.56
Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men. N Engl J Med (2003) 5.95
sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell (2002) 5.66
Alcohol dosing and total mortality in men and women: an updated meta-analysis of 34 prospective studies. Arch Intern Med (2006) 5.34
Dll4, a novel Notch ligand expressed in arterial endothelium. Genes Dev (2000) 3.86
Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development (1996) 3.84
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol (2003) 3.51
Angiopoietins: a link between angiogenesis and inflammation. Trends Immunol (2006) 3.21
Alcohol and cancer. Alcohol Alcohol (2004) 2.82
Notch function in the vasculature: insights from zebrafish, mouse and man. Bioessays (2004) 2.59
Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins. EMBO Rep (2002) 2.21
Coronary collaterals: an important and underexposed aspect of coronary artery disease. Circulation (2003) 2.17
Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2. J Biol Chem (1998) 2.12
Direct cell adhesion to the angiopoietins mediated by integrins. J Biol Chem (2001) 2.11
Lifestyle and the risk of rheumatoid arthritis: cigarette smoking and alcohol consumption. Ann Rheum Dis (1990) 2.07
Binge drinking and mortality after acute myocardial infarction. Circulation (2005) 2.06
Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling. Exp Cell Res (2005) 1.92
Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circ Res (2006) 1.91
The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions. Cancer Res (2006) 1.69
Notch ligand Delta-like 1 is essential for postnatal arteriogenesis. Circ Res (2007) 1.54
Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway. FASEB J (2004) 1.45
Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro. Circ Res (2005) 1.39
Alcohol and heart disease. Circulation (1996) 1.39
Notch signaling in the regulation of tumor angiogenesis. Trends Cell Biol (2006) 1.26
HRT1 modulates vascular smooth muscle cell proliferation and apoptosis. Biochem Biophys Res Commun (2003) 1.22
Coordinate Notch3-hairy-related transcription factor pathway regulation in response to arterial injury. Mediator role of platelet-derived growth factor and ERK. J Biol Chem (2002) 1.19
Hydrogen peroxide formation and actin filament reorganization by Cdc42 are essential for ethanol-induced in vitro angiogenesis. J Biol Chem (2003) 1.19
Ethanol prevents development of destructive arthritis. Proc Natl Acad Sci U S A (2006) 1.18
Coronary collateral circulation: clinical significance and influence on survival in patients with coronary artery occlusion. Am Heart J (1989) 1.17
Notch signaling from tumor cells: a new mechanism of angiogenesis. Cancer Cell (2005) 1.16
Mechanisms which mediate the antiapoptotic effects of angiopoietin-1 on endothelial cells. Microvasc Res (2002) 1.11
Acute ethanol exposure impairs angiogenesis and the proliferative phase of wound healing. Am J Physiol Heart Circ Physiol (2005) 1.11
Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: role in angiogenic activity. Arterioscler Thromb Vasc Biol (2007) 1.09
Neoplastic transformation by Notch is independent of transcriptional activation by RBP-J signalling. Oncogene (2000) 1.06
Ethanol stimulates tumor progression and expression of vascular endothelial growth factor in chick embryos. Cancer (2005) 1.06
Moderate levels of ethanol induce expression of vascular endothelial growth factor and stimulate angiogenesis. Am J Physiol Regul Integr Comp Physiol (2001) 1.04
Endothelial cells inhibit flow-induced smooth muscle cell migration: role of plasminogen activator inhibitor-1. Circulation (2001) 1.04
Ethanol inhibits fibroblast growth factor-induced proliferation of aortic smooth muscle cells. Arterioscler Thromb Vasc Biol (2003) 0.96
Alcohol, wine and mental health: focus on dementia and stroke. J Psychopharmacol (2004) 0.94
Ethanol inhibits mitogen activated protein kinase activity and growth of vascular smooth muscle cells in vitro. Eur J Pharmacol (1998) 0.92
Induction of in vitro angiogenesis in the endothelial-derived cell line, EA hy926, by ethanol is mediated through PKC and MAPK. Biochem Biophys Res Commun (1998) 0.92
Alcohol for the prevention of type 2 diabetes mellitus? Treat Endocrinol (2003) 0.89
Alcohol linked to enhanced angiogenesis in rat model of choroidal neovascularization. FEBS J (2006) 0.87
Pulsatile flow-induced angiogenesis: role of G(i) subunits. Arterioscler Thromb Vasc Biol (2002) 0.86
Acute ethanol increases angiogenic growth factor gene expression in rat skeletal muscle. J Appl Physiol (1985) (2002) 0.82
Ethanol differentially modulates the expression and activity of cell cycle regulatory proteins in rat aortic smooth muscle cells. Eur J Pharmacol (2002) 0.81
Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1: influence on intercellular tight junction assembly and function. Arterioscler Thromb Vasc Biol (2005) 1.89
Natural orifice surgery: initial clinical experience. Surg Endosc (2009) 1.75
Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity. Cardiovasc Res (2004) 1.62
Endothelial Grb2-associated binder 1 is crucial for postnatal angiogenesis. Arterioscler Thromb Vasc Biol (2011) 1.49
Notch and vascular smooth muscle cell phenotype. Circ Res (2008) 1.48
Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway. FASEB J (2004) 1.45
Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro. Am J Physiol Cell Physiol (2005) 1.44
Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro. Circ Res (2005) 1.39
Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma. Liver Int (2005) 1.23
Regulation of bovine brain microvascular endothelial tight junction assembly and barrier function by laminar shear stress. Am J Physiol Heart Circ Physiol (2007) 1.14
Cyclic strain-mediated matrix metalloproteinase regulation within the vascular endothelium: a force to be reckoned with. Am J Physiol Heart Circ Physiol (2006) 1.09
Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: role in angiogenic activity. Arterioscler Thromb Vasc Biol (2007) 1.09
High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway. J Mol Cell Cardiol (2006) 1.06
Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway. J Surg Res (2007) 1.03
Cyclic strain-mediated regulation of vascular endothelial cell migration and tube formation. Biochem Biophys Res Commun (2005) 1.03
Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression. Cancer Res (2011) 1.02
Insulin-like growth factor I is a comitogen for hepatocyte growth factor in a rat model of hepatocellular carcinoma. Hepatology (2002) 0.99
Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A. Arterioscler Thromb Vasc Biol (2009) 0.99
Biomechanical regulation of hedgehog signaling in vascular smooth muscle cells in vitro and in vivo. Am J Physiol Cell Physiol (2006) 0.98
Influence of basolateral condition on the regulation of brain microvascular endothelial tight junction properties and barrier function. Brain Res (2007) 0.97
Video. NOTES: transvaginal cholecystectomy with assisting articulating instruments. Surg Endosc (2009) 0.94
Pulsatile flow increases the expression of eNOS, ET-1, and prostacyclin in a novel in vitro coculture model of the retinal vasculature. Invest Ophthalmol Vis Sci (2005) 0.94
Alcohol inhibits smooth muscle cell proliferation via regulation of the Notch signaling pathway. Arterioscler Thromb Vasc Biol (2010) 0.92
Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes. Int J Biochem Cell Biol (2012) 0.91
Microencapsulation of engineered cells to deliver sustained high circulating levels of interleukin-6 to study hepatocellular carcinoma progression. Cell Transplant (2006) 0.89
The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice. Gastroenterology (2003) 0.89
Thermal behavior and mechanical properties of physically crosslinked PVA/Gelatin hydrogels. J Mech Behav Biomed Mater (2009) 0.89
Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of hedgehog and Notch signaling. Invest Ophthalmol Vis Sci (2011) 0.88
Alcohol and cardiovascular disease--modulation of vascular cell function. Nutrients (2012) 0.87
Inhibition of patched-1 prevents injury-induced neointimal hyperplasia. Arterioscler Thromb Vasc Biol (2013) 0.87
The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation. Cardiovasc Res (2010) 0.86
Pulsatile flow-induced angiogenesis: role of G(i) subunits. Arterioscler Thromb Vasc Biol (2002) 0.86
Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes. Atherosclerosis (2007) 0.85
Pathogenesis of Barrett's esophagus: bile acids inhibit the Notch signaling pathway with induction of CDX2 gene expression in human esophageal cells. Surgery (2009) 0.85
Resveratrol, a polyphenolic phytostilbene, inhibits endothelial monocyte chemotactic protein-1 synthesis and secretion. J Vasc Res (2006) 0.85
Clear and present danger? The use of a yeast biosensor to monitor changes in the toxicity of industrial effluents subjected to oxidative colour removal treatments. J Environ Monit (2007) 0.84
Cell encapsulation and cryostorage in PVA-gelatin cryogels: incorporation of carboxylated ε-poly-L-lysine as cryoprotectant. J Tissue Eng Regen Med (2011) 0.84
Ethanol inhibits pulse pressure-induced vascular smooth muscle cell migration by differentially modulating plasminogen activator inhibitor type 1, matrix metalloproteinase-2 and -9. Thromb Haemost (2005) 0.83
Cyclic strain-induced endothelial MMP-2: role in vascular smooth muscle cell migration. Biochem Biophys Res Commun (2004) 0.83
Glycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: role in cell proliferation and survival. Basic Res Cardiol (2011) 0.83
Ethanol inhibits monocyte chemotactic protein-1 expression in interleukin-1{beta}-activated human endothelial cells. Am J Physiol Heart Circ Physiol (2005) 0.83
Helicobacter pylori-induced inhibition of vascular endothelial cell functions: a role for VacA-dependent nitric oxide reduction. Am J Physiol Heart Circ Physiol (2008) 0.83
Ethanol differentially modulates the expression and activity of cell cycle regulatory proteins in rat aortic smooth muscle cells. Eur J Pharmacol (2002) 0.81
Acute laminar shear stress reversibly increases human glomerular endothelial cell permeability via activation of endothelial nitric oxide synthase. Am J Physiol Renal Physiol (2011) 0.81
Assessment of the genotoxicity of S9-generated metabolites using the GreenScreen HC GADD45a-GFP assay. Mutagenesis (2008) 0.81
Differential effects of daily-moderate versus weekend-binge alcohol consumption on atherosclerotic plaque development in mice. Atherosclerosis (2011) 0.81
Adult vascular smooth muscle cells in culture express neural stem cell markers typical of resident multipotent vascular stem cells. Cell Tissue Res (2014) 0.80
Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner. Atherosclerosis (2008) 0.80
Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJ kappa-dependent pathway. J Virol (2006) 0.80
Hemodynamic regulation of metallopeptidases within the vasculature. Protein Pept Lett (2004) 0.80
Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells. Endothelium (2007) 0.79
Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal SMC or differentiated vascular stem cells? Vasc Cell (2014) 0.79
Cyclic strain amplitude dictates the growth response of vascular smooth muscle cells in vitro: role in in-stent restenosis and inhibition with a sirolimus drug-eluting stent. Biomech Model Mechanobiol (2012) 0.78
Repression of the proapoptotic cellular BIK/NBK gene by Epstein-Barr virus antagonizes transforming growth factor β1-induced B-cell apoptosis. J Virol (2014) 0.78
Investigational Notch and Hedgehog inhibitors--therapies for cardiovascular disease. Expert Opin Investig Drugs (2011) 0.77
Pulse pressure-induced transmural fluid flux increases bovine aortic smooth muscle cell apoptosis in a mitogen activated protein kinase dependent manner. J Vasc Res (2004) 0.77
Eicosanoids in cirrhosis and portal hypertension. Prostaglandins Other Lipid Mediat (2003) 0.77
Flk-1/KDR mediates ethanol-stimulated endothelial cell Notch signaling and angiogenic activity. J Vasc Res (2014) 0.77
Plasminogen activator inhibitor-1 deficiency enhances flow-induced smooth muscle cell migration. Thromb Res (2004) 0.76
Fluorescence polarization discriminates green fluorescent protein from interfering autofluorescence in a microplate assay for genotoxicity. J Biochem Biophys Methods (2002) 0.76
The human genioglossus response to negative airway pressure: stimulus timing and route of delivery. Exp Physiol (2007) 0.76
The NOX-ROS connection: targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells. Cardiovasc Res (2012) 0.75
Endothelialization of PVA/gelatin cryogels for vascular tissue engineering: effect of disturbed shear stress conditions. J Biomed Mater Res A (2010) 0.75
Video. Magnetic retraction for NOTES transvaginal cholecystectomy. Surg Endosc (2010) 0.75
Regulation of endopeptidases EC3.4.24.15 and EC3.4.24.16 in vascular endothelial cells by cyclic strain: role of Gi protein signaling. Arterioscler Thromb Vasc Biol (2004) 0.75