In vivo imaging of membrane-associated glycans in developing zebrafish.

PubWeight™: 5.45‹?› | Rank: Top 1%

🔗 View Article (PMC 2701225)

Published in Science on May 02, 2008

Authors

Scott T Laughlin1, Jeremy M Baskin, Sharon L Amacher, Carolyn R Bertozzi

Author Affiliations

1: Department of Chemistry, University of California, Berkeley, CA 94720, USA.

Articles citing this

(truncated to the top 100)

Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. Angew Chem Int Ed Engl (2009) 8.15

Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem (2008) 3.93

Cu-free click cycloaddition reactions in chemical biology. Chem Soc Rev (2010) 3.89

Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc (2008) 3.65

Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments. Nat Mater (2009) 3.29

Copper-free click chemistry in living animals. Proc Natl Acad Sci U S A (2010) 2.76

Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc (2010) 2.74

Imaging the glycome. Proc Natl Acad Sci U S A (2008) 2.62

Bioorthogonal turn-on probes for imaging small molecules inside living cells. Angew Chem Int Ed Engl (2010) 2.57

From mechanism to mouse: a tale of two bioorthogonal reactions. Acc Chem Res (2011) 2.50

High-efficiency labeling of sialylated glycoproteins on living cells. Nat Methods (2009) 2.46

Fluorescent analogs of biomolecular building blocks: design, properties, and applications. Chem Rev (2010) 2.16

Biomedical applications of tetrazine cycloadditions. Acc Chem Res (2011) 2.10

Biocompatible copper(I) catalysts for in vivo imaging of glycans. J Am Chem Soc (2010) 1.98

Selective labeling of living cells by a photo-triggered click reaction. J Am Chem Soc (2009) 1.89

Labeling live cells by copper-catalyzed alkyne--azide click chemistry. Bioconjug Chem (2010) 1.86

A hydrophilic azacyclooctyne for Cu-free click chemistry. Org Lett (2008) 1.84

Choosing an effective protein bioconjugation strategy. Nat Chem Biol (2011) 1.82

Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation. Bioconjug Chem (2011) 1.78

Visualizing enveloping layer glycans during zebrafish early embryogenesis. Proc Natl Acad Sci U S A (2010) 1.74

Chemical reporters for biological discovery. Nat Chem Biol (2013) 1.69

Increasing the efficacy of bioorthogonal click reactions for bioconjugation: a comparative study. Angew Chem Int Ed Engl (2011) 1.66

Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides. Proc Natl Acad Sci U S A (2011) 1.65

Regulation of O-glycosylation through Golgi-to-ER relocation of initiation enzymes. J Cell Biol (2010) 1.63

Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. Proc Natl Acad Sci U S A (2011) 1.61

Bioorthogonal chemistry: recent progress and future directions. Chem Commun (Camb) (2010) 1.58

A biocompatible condensation reaction for controlled assembly of nanostructures in living cells. Nat Chem (2009) 1.54

Visualizing biochemical activities in living cells. Nat Chem Biol (2009) 1.49

In vivo imaging of Caenorhabditis elegans glycans. ACS Chem Biol (2009) 1.48

Metabolic glycoengineering: sialic acid and beyond. Glycobiology (2009) 1.45

Bringing chemistry to life. Nat Methods (2011) 1.45

Tandem fluorescence imaging of dynamic S-acylation and protein turnover. Proc Natl Acad Sci U S A (2010) 1.44

Ligand-directed tosyl chemistry for protein labeling in vivo. Nat Chem Biol (2009) 1.43

Click chemistry in complex mixtures: bioorthogonal bioconjugation. Chem Biol (2014) 1.40

Selective enrichment of azide-containing peptides from complex mixtures. J Proteome Res (2009) 1.38

Methods for generating and colonizing gnotobiotic zebrafish. Nat Protoc (2008) 1.35

Chemical approaches to perturb, profile, and perceive glycans. Acc Chem Res (2009) 1.33

Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture. Chem Mater (2010) 1.32

Growing applications of "click chemistry" for bioconjugation in contemporary biomedical research. Cancer Biother Radiopharm (2009) 1.30

Non-canonical amino acid labeling in vivo to visualize and affinity purify newly synthesized proteins in larval zebrafish. ACS Chem Neurosci (2012) 1.30

Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin. J Am Chem Soc (2010) 1.29

Cell-surface sensors for real-time probing of cellular environments. Nat Nanotechnol (2011) 1.28

A metabolic alkene reporter for spatiotemporally controlled imaging of newly synthesized proteins in Mammalian cells. ACS Chem Biol (2010) 1.27

Metabolic labeling of fucosylated glycans in developing zebrafish. ACS Chem Biol (2011) 1.25

Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angew Chem Int Ed Engl (2012) 1.25

Proteoglycomics: recent progress and future challenges. OMICS (2010) 1.25

Eight years of single-molecule localization microscopy. Histochem Cell Biol (2014) 1.24

Reactivity of biarylazacyclooctynones in copper-free click chemistry. J Am Chem Soc (2012) 1.24

High-sensitivity analytical approaches for the structural characterization of glycoproteins. Chem Rev (2013) 1.23

Bioorthogonal chemistry: strategies and recent developments. Chem Commun (Camb) (2013) 1.19

ATRP in the design of functional materials for biomedical applications. Prog Polym Sci (2011) 1.15

Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition. J Am Chem Soc (2012) 1.15

Live-cell imaging of cellular proteins by a strain-promoted azide-alkyne cycloaddition. Chembiochem (2010) 1.14

BODIPY-tetrazine derivatives as superbright bioorthogonal turn-on probes. Angew Chem Int Ed Engl (2013) 1.12

Strain-promoted alkyne-azide cycloadditions (SPAAC) reveal new features of glycoconjugate biosynthesis. Chembiochem (2011) 1.10

Targeted identification of metastasis-associated cell-surface sialoglycoproteins in prostate cancer. Mol Cell Proteomics (2011) 1.09

Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine. J Am Chem Soc (2012) 1.09

Copper-free Sonogashira cross-coupling for functionalization of alkyne-encoded proteins in aqueous medium and in bacterial cells. J Am Chem Soc (2011) 1.08

Thiacycloalkynes for copper-free click chemistry. Angew Chem Int Ed Engl (2012) 1.08

Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells. Chem Sci (2011) 1.08

Targeted metabolic labeling of yeast N-glycans with unnatural sugars. Proc Natl Acad Sci U S A (2010) 1.08

Selective enrichment of sialic acid-containing glycopeptides using titanium dioxide chromatography with analysis by HILIC and mass spectrometry. Nat Protoc (2010) 1.07

Probing the mycobacterial trehalome with bioorthogonal chemistry. J Am Chem Soc (2012) 1.06

Imaging the sialome during zebrafish development with copper-free click chemistry. Chembiochem (2012) 1.05

Directing neuronal signaling through cell-surface glycan engineering. J Am Chem Soc (2014) 1.03

A BODIPY-cyclooctyne for protein imaging in live cells. Chembiochem (2011) 1.02

Polar dibenzocyclooctynes for selective labeling of extracellular glycoconjugates of living cells. J Am Chem Soc (2012) 1.01

Tracking N-acetyllactosamine on cell-surface glycans in vivo. Angew Chem Int Ed Engl (2011) 1.01

Direct visualization of specifically modified extracellular glycans in living animals. Nat Methods (2012) 1.01

Uptake, distribution and diffusivity of reactive fluorophores in cells: implications toward target identification. Mol Pharm (2010) 1.00

Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis. Chem Biol (2009) 1.00

Visualizing specific protein glycoforms by transmembrane fluorescence resonance energy transfer. Nat Commun (2012) 1.00

Cytocompatible poly(ethylene glycol)-co-polycarbonate hydrogels cross-linked by copper-free, strain-promoted click chemistry. Chem Asian J (2011) 0.98

CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum. J Am Chem Soc (2015) 0.98

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo. Nat Chem (2014) 0.98

A fluorogenic probe for the catalyst-free detection of azide-tagged molecules. J Am Chem Soc (2012) 0.98

Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry. Bioconjug Chem (2013) 0.97

Hexosamine analogs: from metabolic glycoengineering to drug discovery. Curr Opin Chem Biol (2009) 0.97

A Mild, Large-Scale Synthesis of 1,3-Cyclooctanedione: Expanding Access to Difluorinated Cyclooctyne for Copper-Free Click Chemistry. Tetrahedron Lett (2011) 0.96

A general method for artificial metalloenzyme formation through strain-promoted azide-alkyne cycloaddition. Chembiochem (2013) 0.96

Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials. Nano Today (2011) 0.96

The alpha-galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain. Glycobiology (2009) 0.95

Imaging beyond the proteome. Chem Commun (Camb) (2012) 0.95

Real-time bioluminescence imaging of glycans on live cells. J Am Chem Soc (2010) 0.92

Multispectral labeling of antibodies with polyfluorophores on a DNA backbone and application in cellular imaging. Proc Natl Acad Sci U S A (2011) 0.92

Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations. Biotechnol Bioeng (2011) 0.92

Azirine ligation: fast and selective protein conjugation via photoinduced azirine-alkene cycloaddition. Chem Commun (Camb) (2010) 0.92

Bio-orthogonal phosphatidylserine conjugates for delivery and imaging applications. J Org Chem (2008) 0.91

A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules. ACS Chem Biol (2010) 0.91

Copper-Free Click for PET: Rapid 1,3-Dipolar Cycloadditions with a Fluorine-18 Cyclooctyne. ACS Med Chem Lett (2011) 0.91

Sialic acids attached to O-glycans modulate voltage-gated potassium channel gating. J Biol Chem (2010) 0.90

On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics. Lab Chip (2012) 0.89

Noninvasive imaging of dendrimer-type N-glycan clusters: in vivo dynamics dependence on oligosaccharide structure. Angew Chem Int Ed Engl (2010) 0.89

New chemical probes targeting cholesterylation of Sonic Hedgehog in human cells and zebrafish. Chem Sci (2014) 0.88

Diazo groups endure metabolism and enable chemoselectivity in cellulo. J Am Chem Soc (2015) 0.88

Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy. Am J Nucl Med Mol Imaging (2014) 0.88

In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics. Nat Commun (2016) 0.87

Bioorganic chemistry. A natural reunion of the physical and life sciences. J Org Chem (2009) 0.87

Chemoselective immobilization of peptides on abiotic and cell surfaces at controlled densities. Langmuir (2010) 0.87

Dihydroisoxazole analogs for labeling and visualization of catalytically active transglutaminase 2. Chem Biol (2011) 0.87

Articles cited by this

Stages of embryonic development of the zebrafish. Dev Dyn (1995) 42.72

Copper-free click chemistry for dynamic in vivo imaging. Proc Natl Acad Sci U S A (2007) 8.50

Glycosylation in cellular mechanisms of health and disease. Cell (2006) 8.45

Animal models of human disease: zebrafish swim into view. Nat Rev Genet (2007) 8.36

Chemistry in living systems. Nat Chem Biol (2005) 7.55

Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation. Proc Natl Acad Sci U S A (2001) 4.88

Chemical remodelling of cell surfaces in living animals. Nature (2004) 4.86

Role of glycosylation in development. Annu Rev Biochem (2004) 3.67

NetOglyc: prediction of mucin type O-glycosylation sites based on sequence context and surface accessibility. Glycoconj J (1998) 3.19

Fluorescence visualization of newly synthesized proteins in mammalian cells. Angew Chem Int Ed Engl (2006) 2.96

Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo. Proc Natl Acad Sci U S A (2006) 2.70

A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation. Proc Natl Acad Sci U S A (2003) 2.56

The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags. Trends Cell Biol (2005) 1.98

Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics. Methods Enzymol (2006) 1.93

Probing mucin-type O-linked glycosylation in living animals. Proc Natl Acad Sci U S A (2006) 1.85

Imaging cell surface glycans with bioorthogonal chemical reporters. J Am Chem Soc (2007) 1.65

Mechanisms in protein O-glycan biosynthesis and clinical and molecular aspects of protein O-glycan biosynthesis defects: a review. Clin Chem (2006) 1.46

Polysialic acid in human milk. CD36 is a new member of mammalian polysialic acid-containing glycoprotein. J Biol Chem (2003) 1.41

Characterization of a cell line derived from zebrafish (Brachydanio rerio) embryos. In Vitro Cell Dev Biol Anim (1993) 1.39

Expression of sialyl-Tn epitopes on beta1 integrin alters epithelial cell phenotype, proliferation and haptotaxis. J Cell Sci (2004) 1.33

Assignment of O-glycan attachment sites to the hinge-like regions of human lysosomal membrane glycoproteins lamp-1 and lamp-2. Arch Biochem Biophys (1993) 1.22

Articles by these authors

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases. Nat Biotechnol (2008) 14.20

Copper-free click chemistry for dynamic in vivo imaging. Proc Natl Acad Sci U S A (2007) 8.50

Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. Angew Chem Int Ed Engl (2009) 8.15

Chemistry in living systems. Nat Chem Biol (2005) 7.55

A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems. J Am Chem Soc (2004) 7.51

Glycans in cancer and inflammation--potential for therapeutics and diagnostics. Nat Rev Drug Discov (2005) 6.14

Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation. Proc Natl Acad Sci U S A (2001) 4.88

Chemical remodelling of cell surfaces in living animals. Nature (2004) 4.86

A comparative study of bioorthogonal reactions with azides. ACS Chem Biol (2006) 4.26

Cu-free click cycloaddition reactions in chemical biology. Chem Soc Rev (2010) 3.89

Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc (2008) 3.65

Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes. Nat Biotechnol (2007) 3.41

A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A (2003) 2.97

Copper-free click chemistry in living animals. Proc Natl Acad Sci U S A (2010) 2.76

Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc (2010) 2.74

Introducing genetically encoded aldehydes into proteins. Nat Chem Biol (2007) 2.65

MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc Natl Acad Sci U S A (2003) 2.62

Imaging the glycome. Proc Natl Acad Sci U S A (2008) 2.62

A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation. Proc Natl Acad Sci U S A (2003) 2.56

From mechanism to mouse: a tale of two bioorthogonal reactions. Acc Chem Res (2011) 2.50

The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins. Biochemistry (2008) 2.40

Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligation. J Am Chem Soc (2002) 2.26

Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nat Struct Mol Biol (2004) 2.25

Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Proc Natl Acad Sci U S A (2006) 2.23

Mechanistic investigation of the staudinger ligation. J Am Chem Soc (2005) 2.19

Chemical technologies for probing glycans. Cell (2006) 2.04

A cell nanoinjector based on carbon nanotubes. Proc Natl Acad Sci U S A (2007) 2.00

Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proc Natl Acad Sci U S A (2007) 1.98

Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics. Methods Enzymol (2006) 1.93

Single-cell-resolution imaging of the impact of Notch signaling and mitosis on segmentation clock dynamics. Dev Cell (2012) 1.87

Probing mucin-type O-linked glycosylation in living animals. Proc Natl Acad Sci U S A (2006) 1.85

A hydrophilic azacyclooctyne for Cu-free click chemistry. Org Lett (2008) 1.84

Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. Proc Natl Acad Sci U S A (2009) 1.83

Programmed assembly of 3-dimensional microtissues with defined cellular connectivity. Proc Natl Acad Sci U S A (2009) 1.83

Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations. Chem Biol (2012) 1.79

A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation. Angew Chem Int Ed Engl (2008) 1.79

The chemistry and biology of mucin-type O-linked glycosylation. Bioorg Med Chem (2005) 1.78

Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chem Biol (2004) 1.78

Visualizing enveloping layer glycans during zebrafish early embryogenesis. Proc Natl Acad Sci U S A (2010) 1.74

Sulfotransferases and sulfatases in mycobacteria. Chem Biol (2002) 1.74

Integrated microfluidic bioprocessor for single-cell gene expression analysis. Proc Natl Acad Sci U S A (2008) 1.73

Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation. Nat Protoc (2007) 1.73

Imaging cell surface glycans with bioorthogonal chemical reporters. J Am Chem Soc (2007) 1.65

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc Natl Acad Sci U S A (2010) 1.63

Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. Proc Natl Acad Sci U S A (2011) 1.61

5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Mol Microbiol (2006) 1.59

Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development. Bioconjug Chem (2015) 1.58

Symbol nomenclature for glycan representation. Proteomics (2009) 1.56

Sulfate metabolism in mycobacteria. Chembiochem (2006) 1.55

Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue. FASEB J (2007) 1.55

Metabolic labeling of sialic acids in living animals with alkynyl sugars. Angew Chem Int Ed Engl (2009) 1.53

Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers. Chem Commun (Camb) (2008) 1.52

In vivo imaging of Caenorhabditis elegans glycans. ACS Chem Biol (2009) 1.48

Bringing chemistry to life. Nat Methods (2011) 1.45

Trehalose is required for growth of Mycobacterium smegmatis. J Biol Chem (2004) 1.44

Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. J Mol Biol (2006) 1.42

Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. J Am Chem Soc (2008) 1.41

PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity. J Cell Biol (2012) 1.41

Metabolic oligosaccharide engineering as a tool for glycobiology. Curr Opin Chem Biol (2003) 1.41

Site-specific chemical protein conjugation using genetically encoded aldehyde tags. Nat Protoc (2012) 1.40

Programmable cell adhesion encoded by DNA hybridization. Angew Chem Int Ed Engl (2006) 1.39

Zebrafish slow muscle cell migration induces a wave of fast muscle morphogenesis. Dev Cell (2004) 1.38

Selective enrichment of azide-containing peptides from complex mixtures. J Proteome Res (2009) 1.38

Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase. Glycobiology (2005) 1.35

A chemical reporter strategy to probe glycoprotein fucosylation. J Am Chem Soc (2006) 1.35

Interactions between muscle fibers and segment boundaries in zebrafish. Dev Biol (2005) 1.35

Function and structure of a prokaryotic formylglycine-generating enzyme. J Biol Chem (2008) 1.35

A conserved mechanism for sulfonucleotide reduction. PLoS Biol (2005) 1.34

Copper-diamine-catalyzed N-arylation of pyrroles, pyrazoles, indazoles, imidazoles, and triazoles. J Org Chem (2004) 1.34

Membrane proteomics of phagosomes suggests a connection to autophagy. Proc Natl Acad Sci U S A (2008) 1.34

Chemical approaches to perturb, profile, and perceive glycans. Acc Chem Res (2009) 1.33

A decade of bioorthogonal chemistry. Acc Chem Res (2011) 1.32

Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells. J Am Chem Soc (2009) 1.31

Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog. FASEB J (2007) 1.31

Direct cell surface modification with DNA for the capture of primary cells and the investigation of myotube formation on defined patterns. Langmuir (2009) 1.30

(D)-Amino acid chemical reporters reveal peptidoglycan dynamics of an intracellular pathogen. ACS Chem Biol (2013) 1.29

Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin. J Am Chem Soc (2010) 1.29

Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl Environ Microbiol (2010) 1.29

A fluorogenic dye activated by the staudinger ligation. J Am Chem Soc (2003) 1.29

Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries. Development (2002) 1.29

Expanding the diversity of unnatural cell-surface sialic acids. Chembiochem (2004) 1.29

5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria. J Biol Chem (2002) 1.27

Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach. Proc Natl Acad Sci U S A (2002) 1.26

Metabolic labeling of fucosylated glycans in developing zebrafish. ACS Chem Biol (2011) 1.25

Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angew Chem Int Ed Engl (2012) 1.25

PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proc Natl Acad Sci U S A (2007) 1.25

Interfacing carbon nanotubes with living cells. J Am Chem Soc (2006) 1.25

Reactivity of biarylazacyclooctynones in copper-free click chemistry. J Am Chem Soc (2012) 1.24

An inhibitor of the human UDP-GlcNAc 4-epimerase identified from a uridine-based library: a strategy to inhibit O-linked glycosylation. Chem Biol (2002) 1.22