Published in Chembiochem on October 01, 2006
targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis. BMC Syst Biol (2008) 1.84
NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis. Genome Biol (2009) 1.66
S-box and T-box riboswitches and antisense RNA control a sulfur metabolic operon of Clostridium acetobutylicum. Nucleic Acids Res (2008) 1.47
Drug targets in mycobacterial sulfur metabolism. Infect Disord Drug Targets (2007) 1.45
High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling. PLoS Pathog (2010) 1.45
Crystal structures of the kinase domain of the sulfate-activating complex in Mycobacterium tuberculosis. PLoS One (2015) 1.39
Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. BMC Infect Dis (2007) 1.32
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proc Natl Acad Sci U S A (2007) 1.25
Physiology of mycobacteria. Adv Microb Physiol (2009) 1.23
The Mycobacterium tuberculosis cytochrome P450 system. Arch Biochem Biophys (2009) 1.16
The regulation of sulfur metabolism in Mycobacterium tuberculosis. PLoS Pathog (2011) 1.15
Rv2131c from Mycobacterium tuberculosis is a CysQ 3'-phosphoadenosine-5'-phosphatase. Biochemistry (2008) 1.07
PapA3 is an acyltransferase required for polyacyltrehalose biosynthesis in Mycobacterium tuberculosis. J Biol Chem (2009) 1.06
Structural characterization of a novel sulfated menaquinone produced by stf3 from Mycobacterium tuberculosis. ACS Chem Biol (2008) 1.03
Bioluminescent probes of sulfatase activity. Chembiochem (2010) 0.97
Structure-based virtual screening and biological evaluation of Mycobacterium tuberculosis adenosine 5'-phosphosulfate reductase inhibitors. J Med Chem (2008) 0.97
An expanded set of fluorogenic sulfatase activity probes. Chembiochem (2014) 0.96
Characterization of NrnA homologs from Mycobacterium tuberculosis and Mycoplasma pneumoniae. RNA (2011) 0.94
Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase. J Med Chem (2009) 0.94
The Mycobacterium tuberculosis virulence factor trehalose dimycolate imparts desiccation resistance to model mycobacterial membranes. Biophys J (2008) 0.93
Sulfate activation in mitosomes plays an important role in the proliferation of Entamoeba histolytica. PLoS Negl Trop Dis (2011) 0.93
Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. ACS Chem Biol (2012) 0.92
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains. Proc Natl Acad Sci U S A (2013) 0.91
Mycobacteria isolated from angkor monument sandstones grow chemolithoautotrophically by oxidizing elemental sulfur. Front Microbiol (2011) 0.89
Nucleotide binding site communication in Arabidopsis thaliana adenosine 5'-phosphosulfate kinase. J Biol Chem (2012) 0.86
The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth. Bioorg Med Chem Lett (2011) 0.86
New targets and inhibitors of mycobacterial sulfur metabolism. Infect Disord Drug Targets (2013) 0.83
Global regulation of the response to sulfur availability in the cheese-related bacterium Brevibacterium aurantiacum. Appl Environ Microbiol (2010) 0.82
Increased sulfate uptake by E. coli overexpressing the SLC26-related SulP protein Rv1739c from Mycobacterium tuberculosis. Comp Biochem Physiol A Mol Integr Physiol (2007) 0.81
Uncovering potential Drug Targets for Tuberculosis using Protein Networks. Bioinformation (2012) 0.80
Iron-sulfur cluster engineering provides insight into the evolution of substrate specificity among sulfonucleotide reductases. ACS Chem Biol (2011) 0.80
A high-throughput screening fluorescence polarization assay for fatty acid adenylating enzymes in Mycobacterium tuberculosis. Anal Biochem (2011) 0.79
Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosis. J Infect Dis (2012) 0.77
Isozyme-specific ligands for O-acetylserine sulfhydrylase, a novel antibiotic target. PLoS One (2013) 0.77
Marine sponge derived natural products as inhibitors of mycothiol-S-conjugate amidase. Bioinformation (2017) 0.75
Copper-free click chemistry for dynamic in vivo imaging. Proc Natl Acad Sci U S A (2007) 8.50
Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. Angew Chem Int Ed Engl (2009) 8.15
Chemistry in living systems. Nat Chem Biol (2005) 7.55
A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems. J Am Chem Soc (2004) 7.51
Glycans in cancer and inflammation--potential for therapeutics and diagnostics. Nat Rev Drug Discov (2005) 6.14
In vivo imaging of membrane-associated glycans in developing zebrafish. Science (2008) 5.45
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation. Proc Natl Acad Sci U S A (2001) 4.88
Chemical remodelling of cell surfaces in living animals. Nature (2004) 4.86
A comparative study of bioorthogonal reactions with azides. ACS Chem Biol (2006) 4.26
Cu-free click cycloaddition reactions in chemical biology. Chem Soc Rev (2010) 3.89
Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc (2008) 3.65
Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes. Nat Biotechnol (2007) 3.41
A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A (2003) 2.97
Copper-free click chemistry in living animals. Proc Natl Acad Sci U S A (2010) 2.76
Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc (2010) 2.74
Introducing genetically encoded aldehydes into proteins. Nat Chem Biol (2007) 2.65
Imaging the glycome. Proc Natl Acad Sci U S A (2008) 2.62
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc Natl Acad Sci U S A (2003) 2.62
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation. Proc Natl Acad Sci U S A (2003) 2.56
From mechanism to mouse: a tale of two bioorthogonal reactions. Acc Chem Res (2011) 2.50
The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins. Biochemistry (2008) 2.40
Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligation. J Am Chem Soc (2002) 2.26
Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nat Struct Mol Biol (2004) 2.25
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Proc Natl Acad Sci U S A (2006) 2.23
Mechanistic investigation of the staudinger ligation. J Am Chem Soc (2005) 2.19
Chemical technologies for probing glycans. Cell (2006) 2.04
A cell nanoinjector based on carbon nanotubes. Proc Natl Acad Sci U S A (2007) 2.00
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proc Natl Acad Sci U S A (2007) 1.98
Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics. Methods Enzymol (2006) 1.93
Probing mucin-type O-linked glycosylation in living animals. Proc Natl Acad Sci U S A (2006) 1.85
A hydrophilic azacyclooctyne for Cu-free click chemistry. Org Lett (2008) 1.84
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. Proc Natl Acad Sci U S A (2009) 1.83
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity. Proc Natl Acad Sci U S A (2009) 1.83
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations. Chem Biol (2012) 1.79
A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation. Angew Chem Int Ed Engl (2008) 1.79
The chemistry and biology of mucin-type O-linked glycosylation. Bioorg Med Chem (2005) 1.78
Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chem Biol (2004) 1.78
Visualizing enveloping layer glycans during zebrafish early embryogenesis. Proc Natl Acad Sci U S A (2010) 1.74
Sulfotransferases and sulfatases in mycobacteria. Chem Biol (2002) 1.74
Integrated microfluidic bioprocessor for single-cell gene expression analysis. Proc Natl Acad Sci U S A (2008) 1.73
Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation. Nat Protoc (2007) 1.73
Imaging cell surface glycans with bioorthogonal chemical reporters. J Am Chem Soc (2007) 1.65
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc Natl Acad Sci U S A (2010) 1.63
Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. Proc Natl Acad Sci U S A (2011) 1.61
5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Mol Microbiol (2006) 1.59
Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development. Bioconjug Chem (2015) 1.58
Symbol nomenclature for glycan representation. Proteomics (2009) 1.56
Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue. FASEB J (2007) 1.55
Metabolic labeling of sialic acids in living animals with alkynyl sugars. Angew Chem Int Ed Engl (2009) 1.53
Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers. Chem Commun (Camb) (2008) 1.52
In vivo imaging of Caenorhabditis elegans glycans. ACS Chem Biol (2009) 1.48
Bringing chemistry to life. Nat Methods (2011) 1.45
Trehalose is required for growth of Mycobacterium smegmatis. J Biol Chem (2004) 1.44
Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. J Mol Biol (2006) 1.42
Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. J Am Chem Soc (2008) 1.41
Metabolic oligosaccharide engineering as a tool for glycobiology. Curr Opin Chem Biol (2003) 1.41
Site-specific chemical protein conjugation using genetically encoded aldehyde tags. Nat Protoc (2012) 1.40
Programmable cell adhesion encoded by DNA hybridization. Angew Chem Int Ed Engl (2006) 1.39
Selective enrichment of azide-containing peptides from complex mixtures. J Proteome Res (2009) 1.38
Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase. Glycobiology (2005) 1.35
A chemical reporter strategy to probe glycoprotein fucosylation. J Am Chem Soc (2006) 1.35
Function and structure of a prokaryotic formylglycine-generating enzyme. J Biol Chem (2008) 1.35
A conserved mechanism for sulfonucleotide reduction. PLoS Biol (2005) 1.34
Membrane proteomics of phagosomes suggests a connection to autophagy. Proc Natl Acad Sci U S A (2008) 1.34
Chemical approaches to perturb, profile, and perceive glycans. Acc Chem Res (2009) 1.33
A decade of bioorthogonal chemistry. Acc Chem Res (2011) 1.32
Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells. J Am Chem Soc (2009) 1.31
Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog. FASEB J (2007) 1.31
Direct cell surface modification with DNA for the capture of primary cells and the investigation of myotube formation on defined patterns. Langmuir (2009) 1.30
(D)-Amino acid chemical reporters reveal peptidoglycan dynamics of an intracellular pathogen. ACS Chem Biol (2013) 1.29
Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin. J Am Chem Soc (2010) 1.29
A fluorogenic dye activated by the staudinger ligation. J Am Chem Soc (2003) 1.29
Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl Environ Microbiol (2010) 1.29
Expanding the diversity of unnatural cell-surface sialic acids. Chembiochem (2004) 1.29
5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria. J Biol Chem (2002) 1.27
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach. Proc Natl Acad Sci U S A (2002) 1.26
Metabolic labeling of fucosylated glycans in developing zebrafish. ACS Chem Biol (2011) 1.25
Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angew Chem Int Ed Engl (2012) 1.25
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proc Natl Acad Sci U S A (2007) 1.25
Interfacing carbon nanotubes with living cells. J Am Chem Soc (2006) 1.25
Reactivity of biarylazacyclooctynones in copper-free click chemistry. J Am Chem Soc (2012) 1.24
An inhibitor of the human UDP-GlcNAc 4-epimerase identified from a uridine-based library: a strategy to inhibit O-linked glycosylation. Chem Biol (2002) 1.22
Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. J Lipid Res (2009) 1.20
Metabolic functionalization of recombinant glycoproteins. Biochemistry (2004) 1.19
Synthesis, characterization, and theory of [9]-, [12]-, and [18]cycloparaphenylene: carbon nanohoop structures. J Am Chem Soc (2008) 1.19
A new approach to mineralization of biocompatible hydrogel scaffolds: an efficient process toward 3-dimensional bonelike composites. J Am Chem Soc (2003) 1.18
Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications. Angew Chem Int Ed Engl (2009) 1.18
A chemical method for labeling lysine methyltransferase substrates. Chembiochem (2010) 1.18
A sulfated metabolite produced by stf3 negatively regulates the virulence of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 1.16
Synthetic glycopeptides and glycoproteins as tools for biology. Chem Soc Rev (2004) 1.16
Probing glycosyltransferase activities with the Staudinger ligation. J Am Chem Soc (2004) 1.15
The regulation of sulfur metabolism in Mycobacterium tuberculosis. PLoS Pathog (2011) 1.15
Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition. J Am Chem Soc (2012) 1.15
The roles of enzyme localisation and complex formation in glycan assembly within the Golgi apparatus. Curr Opin Cell Biol (2004) 1.15
Drug targeting Mycobacterium tuberculosis cell wall synthesis: development of a microtiter plate-based screen for UDP-galactopyranose mutase and identification of an inhibitor from a uridine-based library. Antimicrob Agents Chemother (2003) 1.14
Live-cell imaging of cellular proteins by a strain-promoted azide-alkyne cycloaddition. Chembiochem (2010) 1.14
Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes. Proc Natl Acad Sci U S A (2014) 1.14
A strategy for functional proteomic analysis of glycosidase activity from cell lysates. Angew Chem Int Ed Engl (2004) 1.14
Azido sialic acids can modulate cell-surface interactions. Chembiochem (2004) 1.14
Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag. J Am Chem Soc (2011) 1.13