Published in J Mol Biol on April 04, 2008
Molecular aspects of bacterial pH sensing and homeostasis. Nat Rev Microbiol (2011) 2.46
Characterization of single chain antibody targets through yeast two hybrid. BMC Biotechnol (2010) 0.85
Cysteine-free proteins in the immunobiology of arthropod-borne diseases. J Biomed Biotechnol (2010) 0.75
Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH. Nature (2005) 3.74
Cardiolipin stabilizes respiratory chain supercomplexes. J Biol Chem (2003) 3.16
Lipids in membrane protein structures. Biochim Biophys Acta (2004) 2.67
Overcoming barriers to membrane protein structure determination. Nat Biotechnol (2011) 2.49
Molecular aspects of bacterial pH sensing and homeostasis. Nat Rev Microbiol (2011) 2.46
Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c. Proc Natl Acad Sci U S A (2002) 1.82
Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer. J Biol Chem (2008) 1.71
The structure of cbb3 cytochrome oxidase provides insights into proton pumping. Science (2010) 1.68
Crystallisation of membrane proteins mediated by antibody fragments. Curr Opin Struct Biol (2002) 1.50
Alkalitolerance: a biological function for a multidrug transporter in pH homeostasis. Proc Natl Acad Sci U S A (2004) 1.46
Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen. Protein Sci (2006) 1.46
Structure of the yeast cytochrome bc1 complex with a hydroxyquinone anion Qo site inhibitor bound. J Biol Chem (2003) 1.43
Role of phospholipids in respiratory cytochrome bc(1) complex catalysis and supercomplex formation. Biochim Biophys Acta (2009) 1.38
Discontinuous membrane helices in transport proteins and their correlation with function. J Struct Biol (2007) 1.38
Do physiological roles foster persistence of drug/multidrug-efflux transporters? A case study. Nat Rev Microbiol (2005) 1.36
Direct observation of tiers in the energy landscape of a chromoprotein: a single-molecule study. Proc Natl Acad Sci U S A (2003) 1.33
Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications. J Biol Chem (2007) 1.32
Transport mechanism and pH regulation of the Na+/H+ antiporter NhaA from Escherichia coli: an electrophysiological study. J Biol Chem (2011) 1.31
The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration. Proc Natl Acad Sci U S A (2009) 1.26
Dynamic water networks in cytochrome C oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations. Biophys J (2004) 1.26
Reduction of cytochrome c oxidase by a second electron leads to proton translocation. Nature (2002) 1.25
Assessing oligomerization of membrane proteins by four-pulse DEER: pH-dependent dimerization of NhaA Na+/H+ antiporter of E. coli. Biophys J (2005) 1.24
Molecular basis for atovaquone binding to the cytochrome bc1 complex. J Biol Chem (2003) 1.21
Comparative analysis and "expression space" coverage of the production of prokaryotic membrane proteins for structural genomics. Protein Sci (2006) 1.21
High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: new insights into the active site and the proton transfer pathways. Biochim Biophys Acta (2009) 1.20
Single-molecule study of the electronic couplings in a circular array of molecules: light-harvesting-2 complex from Rhodospirillum molischianum. Phys Rev Lett (2003) 1.20
Trans membrane domain IV is involved in ion transport activity and pH regulation of the NhaA-Na(+)/H(+) antiporter of Escherichia coli. Biochemistry (2002) 1.17
Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane. Mol Cell (2011) 1.14
Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation. Cell (2013) 1.11
Phosphatidylethanolamine and cardiolipin differentially affect the stability of mitochondrial respiratory chain supercomplexes. J Mol Biol (2012) 1.10
Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis. Structure (2007) 1.10
Mutation E252C increases drastically the Km value for Na+ and causes an alkaline shift of the pH dependence of NhaA Na+/H+ antiporter of Escherichia coli. J Biol Chem (2003) 1.09
Multiconformation continuum electrostatics analysis of the NhaA Na+/H+ antiporter of Escherichia coli with functional implications. Proc Natl Acad Sci U S A (2006) 1.08
Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems. J Struct Funct Genomics (2006) 1.08
The MAM (meprin/A5-protein/PTPmu) domain is a homophilic binding site promoting the lateral dimerization of receptor-like protein-tyrosine phosphatase mu. J Biol Chem (2004) 1.08
A new structure-based classification of sulfide:quinone oxidoreductases. Proteins (2010) 1.05
A D-pathway mutation decouples the Paracoccus denitrificans cytochrome c oxidase by altering the side-chain orientation of a distant conserved glutamate. J Mol Biol (2008) 1.05
Unraveling functional and structural interactions between transmembrane domains IV and XI of NhaA Na+/H+ antiporter of Escherichia coli. J Biol Chem (2004) 1.04
Monomers of the NhaA Na+/H+ antiporter of Escherichia coli are fully functional yet dimers are beneficial under extreme stress conditions at alkaline pH in the presence of Na+ or Li+. J Biol Chem (2007) 1.04
Structure-based functional study reveals multiple roles of transmembrane segment IX and loop VIII-IX in NhaA Na+/H+ antiporter of Escherichia coli at physiological pH. J Biol Chem (2008) 1.03
Roles of NhaA, NhaB, and NhaD Na+/H+ antiporters in survival of Vibrio cholerae in a saline environment. J Bacteriol (2003) 1.02
Titration behavior of residues at the entrance of the D-pathway of cytochrome c oxidase from paracoccus denitrificans investigated by continuum electrostatic calculations. Biophys J (2005) 1.02
Cell free expression and functional reconstitution of eukaryotic drug transporters. Biochemistry (2008) 1.01
The influence of protonation states on the dynamics of the NhaA antiporter from Escherichia coli. Biophys J (2007) 1.00
Mutational analysis of cytochrome b at the ubiquinol oxidation site of yeast complex III. J Biol Chem (2006) 1.00
Functional implications from an unexpected position of the 49-kDa subunit of NADH:ubiquinone oxidoreductase. J Biol Chem (2003) 0.99
Functional and structural interactions of the transmembrane domain X of NhaA, Na+/H+ antiporter of Escherichia coli, at physiological pH. Biochemistry (2007) 0.98
Beta-sheet-dependent dimerization is essential for the stability of NhaA Na+/H+ antiporter. J Biol Chem (2009) 0.97
Isolation, characterization and electron microscopic single particle analysis of the NADH:ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium Aquifex aeolicus. Biochemistry (2003) 0.97
Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family. Biochim Biophys Acta (2004) 0.97
High level production of functional antibody Fab fragments in an oxidizing bacterial cytoplasm. J Mol Biol (2002) 0.96
A comparison of stigmatellin conformations, free and bound to the photosynthetic reaction center and the cytochrome bc1 complex. J Mol Biol (2007) 0.96
Tyrosine 167: the origin of the radical species observed in the reaction of cytochrome c oxidase with hydrogen peroxide in Paracoccus denitrificans. Biochemistry (2004) 0.95
Crucial steps in the structure determination of the Na+/H+ antiporter NhaA in its native conformation. J Mol Biol (2006) 0.95
Model-guided mutagenesis drives functional studies of human NHA2, implicated in hypertension. J Mol Biol (2010) 0.95
Revealing the ligand binding site of NhaA Na+/H+ antiporter and its pH dependence. J Biol Chem (2012) 0.95
Heterologous expression and comparative characterization of the human neuromedin U subtype II receptor using the methylotrophic yeast Pichia pastoris and mammalian cells. Int J Biochem Cell Biol (2007) 0.94
Editorial: the nonsense of biofuels. Angew Chem Int Ed Engl (2012) 0.94
Transmembrane segment II of NhaA Na+/H+ antiporter lines the cation passage, and Asp65 is critical for pH activation of the antiporter. J Biol Chem (2009) 0.94
The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization. J Biol Chem (2011) 0.94
Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons. Biochim Biophys Acta (2004) 0.92
Probing the role of E272 in quinol oxidation of mitochondrial complex III. Biochemistry (2006) 0.92
A model-structure of a periplasm-facing state of the NhaA antiporter suggests the molecular underpinnings of pH-induced conformational changes. J Biol Chem (2012) 0.92
Dimethylsulphoxide as a tool to increase functional expression of heterologously produced GPCRs in mammalian cells. FEBS Lett (2006) 0.91
Heterologous expression of human Neuromedin U receptor 1 and its subsequent solubilization and purification. Biochim Biophys Acta (2008) 0.91
Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. J Cell Biol (2012) 0.91
Crystallization and preliminary X-ray analysis of strictosidine synthase and its complex with the substrate tryptamine. Acta Crystallogr D Biol Crystallogr (2005) 0.89
Characterization of two different acyl carrier proteins in complex I from Yarrowia lipolytica. Biochim Biophys Acta (2009) 0.89
Multivariate analysis of single-molecule spectra: surpassing spectral diffusion. Phys Rev Lett (2005) 0.89
The role of tryptophan 272 in the Paracoccus denitrificans cytochrome c oxidase. FEBS Lett (2006) 0.89
X-ray structure of the dimeric cytochrome bc(1) complex from the soil bacterium Paracoccus denitrificans at 2.7-Å resolution. Biochim Biophys Acta (2011) 0.89
The nitrite transport protein NirC from Salmonella typhimurium is a nitrite/proton antiporter. Biochim Biophys Acta (2012) 0.88
Employing Rhodobacter sphaeroides to functionally express and purify human G protein-coupled receptors. Biol Chem (2008) 0.88
Site-directed tryptophan fluorescence reveals two essential conformational changes in the Na+/H+ antiporter NhaA. Proc Natl Acad Sci U S A (2011) 0.88
Vibrational modes of tyrosines in cytochrome c oxidase from Paracoccus denitrificans: FTIR and electrochemical studies on Tyr-D4-labeled and on Tyr280His and Tyr35Phe mutant enzymes. Biochemistry (2002) 0.87
Biochemical and biophysical characterization of the two isoforms of cbb3-type cytochrome c oxidase from Pseudomonas stutzeri. J Bacteriol (2013) 0.87
Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex. Mol Biol Cell (2011) 0.86
A L-lysine transporter of high stereoselectivity of the amino acid-polyamine-organocation (APC) superfamily: production, functional characterization, and structure modeling. J Biol Chem (2013) 0.85
Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1. J Mol Biol (2007) 0.85
Conformational changes in NhaA Na+/H+ antiporter. Mol Membr Biol (2012) 0.85
Functional analysis of cell-free-produced human endothelin B receptor reveals transmembrane segment 1 as an essential area for ET-1 binding and homodimer formation. FEBS J (2007) 0.85
Characterizing a monotopic membrane enzyme. Biochemical, enzymatic and crystallization studies on Aquifex aeolicus sulfide:quinone oxidoreductase. Biochim Biophys Acta (2010) 0.83
Production of the human D2S receptor in the methylotrophic yeast P. pastoris. Receptors Channels (2004) 0.83
Rates and Equilibrium of CuA to heme a electron transfer in Paracoccus denitrificans cytochrome c oxidase. Biophys J (2005) 0.83
The structure of the neuropeptide bradykinin bound to the human G-protein coupled receptor bradykinin B2 as determined by solid-state NMR spectroscopy. Angew Chem Int Ed Engl (2008) 0.83
Redox-linked protonation state changes in cytochrome bc1 identified by Poisson-Boltzmann electrostatics calculations. Biochim Biophys Acta (2007) 0.83
Helix VIII of NhaA Na(+)/H(+) antiporter participates in the periplasmic cation passage and pH regulation of the antiporter. J Mol Biol (2011) 0.82
Elucidating mechanisms in haem copper oxidases: the high-affinity QH binding site in quinol oxidase as studied by DONUT-HYSCORE spectroscopy and density functional theory. Faraday Discuss (2011) 0.82
Net proton uptake is preceded by multiple proton transfer steps upon electron injection into cytochrome c oxidase. J Biol Chem (2012) 0.82
Monoclonal antibodies for the structural analysis of the Na+/H+ antiporter NhaA from Escherichia coli. Biochim Biophys Acta (2003) 0.81
Comparative analysis of the human angiotensin II type 1a receptor heterologously produced in insect cells and mammalian cells. Biochem Biophys Res Commun (2006) 0.81
2-Aminoperimidine, a specific inhibitor of bacterial NhaA Na(+)/H(+) antiporters. FEBS Lett (2005) 0.81