Published in Br J Pharmacol on May 05, 2008
Molecular mechanism of macrophage activation by red ginseng acidic polysaccharide from Korean red ginseng. Mediators Inflamm (2012) 1.24
Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effects. J Biol Chem (2010) 1.14
20S-dihydroprotopanaxatriol modulates functional activation of monocytes and macrophages. J Ginseng Res (2013) 1.06
AP-1/IRF-3 Targeted Anti-Inflammatory Activity of Andrographolide Isolated from Andrographis paniculata. Evid Based Complement Alternat Med (2013) 0.94
Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark. BMC Complement Altern Med (2014) 0.89
The dietary flavonoid Kaempferol mediates anti-inflammatory responses via the Src, Syk, IRAK1, and IRAK4 molecular targets. Mediators Inflamm (2015) 0.84
Nanostructured, self-assembling peptide K5 blocks TNF-α and PGE₂ production by suppression of the AP-1/p38 pathway. Mediators Inflamm (2012) 0.83
Suppressive effect of hydroquinone, a benzene metabolite, on in vitro inflammatory responses mediated by macrophages, monocytes, and lymphocytes. Mediators Inflamm (2009) 0.83
21-O-angeloyltheasapogenol E3, a novel triterpenoid saponin from the seeds of tea plants, inhibits macrophage-mediated inflammatory responses in a NF-κB-dependent manner. Mediators Inflamm (2014) 0.83
In vitro and in vivo anti-inflammatory activities of Korean Red Ginseng-derived components. J Ginseng Res (2016) 0.83
NF-κB/AP-1-targeted inhibition of macrophage-mediated inflammatory responses by depigmenting compound AP736 derived from natural 1,3-diphenylpropane skeleton. Mediators Inflamm (2014) 0.81
Lancemaside A from Codonopsis lanceolata modulates the inflammatory responses mediated by monocytes and macrophages. Mediators Inflamm (2014) 0.80
Cytochalasin B modulates macrophage-mediated inflammatory responses. Biomol Ther (Seoul) (2014) 0.79
HangAmDan-B, an ethnomedicinal herbal mixture, suppresses inflammatory responses by inhibiting Syk/NF-κB and JNK/ATF-2 pathways. J Med Food (2012) 0.78
Kinase activity profiling of gram-negative pneumonia. Mol Med (2011) 0.78
p38/AP-1 pathway in lipopolysaccharide-induced inflammatory responses is negatively modulated by electrical stimulation. Mediators Inflamm (2013) 0.76
An Antioxidant Davallialactone from Phellinus baumii Enhances Sperm Penetration on In Vitro Fertilization of Pigs. Mycobiology (2016) 0.75
AP-1-Targeted Anti-Inflammatory Activities of the Nanostructured, Self-Assembling S5 Peptide. Mediators Inflamm (2015) 0.75
Nuclear factor kappa-B- and activator protein-1-mediated immunostimulatory activity of compound K in monocytes and macrophages. J Ginseng Res (2016) 0.75
Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J Biol Chem (2001) 2.03
Naturally occurring NF-kappaB inhibitors. Mini Rev Med Chem (2006) 1.78
Signal transduction of inflammatory cytokines and tumor development. Cancer Sci (2006) 1.78
Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors. J Immunol (1996) 1.75
In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa. Eur J Pharmacol (2000) 1.70
Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J Immunol (2003) 1.54
Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kappaB through Akt and p38 inhibition in RAW 264.7 macrophage cells. Eur J Pharmacol (2006) 1.51
Pneumocystis cell wall beta-glucans stimulate alveolar epithelial cell chemokine generation through nuclear factor-kappaB-dependent mechanisms. Am J Respir Cell Mol Biol (2005) 1.45
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity. J Biol Chem (2001) 1.30
Inhibitory effect of curcumin on nitric oxide production from lipopolysaccharide-activated primary microglia. Life Sci (2006) 1.28
Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury. J Immunol (2007) 1.23
Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm (2005) 1.19
Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages. Mol Immunol (2007) 1.14
New responsibilities for the PI3K regulatory subunit p85 alpha. Sci STKE (2001) 1.11
Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation. J Immunol (2002) 1.11
Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages. Mol Immunol (2006) 1.11
The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis. Arthritis Res Ther (2006) 1.09
Enzymatic hydrolysis of water-soluble wheat arabinoxylan. 1. Synergy between alpha-L-arabinofuranosidases, endo-1,4-beta-xylanases, and beta-xylosidase activities. Biotechnol Bioeng (2003) 1.08
The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages. Br J Pharmacol (2006) 1.08
Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity. Bioorg Med Chem Lett (2006) 1.02
Ergosterol peroxide from an edible mushroom suppresses inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells. Br J Pharmacol (2006) 1.01
Savinin, a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell proliferation. Biol Pharm Bull (2001) 1.00
The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88-independent signaling pathways of Toll-like receptor 4. Biochem Pharmacol (2005) 0.97
Pi 3-kinase and its up- and down-stream modulators as potential targets for the treatment of type II diabetes. Front Biosci (2002) 0.96
The mechanism of anti-platelet activity of davallialactone: involvement of intracellular calcium ions, extracellular signal-regulated kinase 2 and p38 mitogen-activated protein kinase. Eur J Pharmacol (2008) 0.93
Controlled modulation of inflammatory, stress and apoptotic responses in macrophages. Curr Drug Targets Immune Endocr Metabol Disord (2003) 0.93
Cynaropicrin, a sesquiterpene lactone, as a new strong regulator of CD29 and CD98 functions. Biochem Biophys Res Commun (2004) 0.92
Oxidative stress reprograms lipopolysaccharide signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line. J Biol Chem (2003) 0.92
Pulmonary innate immune proteins and receptors that interact with gram-positive bacterial ligands. Immunobiology (2002) 0.92
Negative regulators of toll-like receptor 4-mediated macrophage inflammatory response. Curr Pharm Des (2006) 0.91
In vitro anti-inflammatory and pro-aggregative effects of a lipid compound, petrocortyne A, from marine sponges. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.90
Structures, biogenesis, and biological activities of pyrano[4,3-c]isochromen-4-one derivatives from the Fungus Phellinus igniarius. J Nat Prod (2007) 0.86
Differential effect of phosphodiesterase IV inhibitor RP73401 on various inflammatory and immune responses relevent to rheumatoid arthritis. Pharmacol Res (2004) 0.83
Hispidin derivatives from the mushroom Inonotus xeranticus and their antioxidant activity. J Nat Prod (2006) 0.81
Effects of a redox-active agent on lymphocyte activation and early gene expression patterns. Free Radic Biol Med (2004) 0.79
A beta-D-glucan isolated from the fruiting bodies of Hericium erinaceus and its aqueous conformation. Carbohydr Res (2006) 0.79
Anti-inflammatory cyathane diterpenoids from Sarcodon scabrosus. Biosci Biotechnol Biochem (2004) 0.77
NF-kappa B--a target in the inflammation of bone destruction. Expert Opin Ther Targets (2005) 0.77
Structure elucidation of clavilactone D: an inhibitor of protein tyrosine kinases. Phytochemistry (2000) 0.77
Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N Engl J Med (1998) 14.40
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat Med (1998) 8.62
Community-based approaches to HIV treatment in resource-poor settings. Lancet (2001) 7.13
Community-based treatment of advanced HIV disease: introducing DOT-HAART (directly observed therapy with highly active antiretroviral therapy). Bull World Health Organ (2001) 6.07
The dilemma of MDR-TB in the global era. Int J Tuberc Lung Dis (1998) 5.77
Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity (1999) 5.34
Community based approaches to the control of multidrug resistant tuberculosis: introducing "DOTS-plus". BMJ (1998) 4.79
Acetaminophen toxicity in an urban county hospital. N Engl J Med (1997) 4.26
alpha-Synuclein gene duplication is present in sporadic Parkinson disease. Neurology (2007) 3.62
Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial. Ann Intern Med (1994) 3.53
Identification of the human c-myc protein nuclear translocation signal. Mol Cell Biol (1988) 3.30
Efficiency enhancement in low-bandgap polymer solar cells by processing with alkane dithiols. Nat Mater (2007) 3.18
Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels. Kidney Int (2007) 3.17
Rapid and sensitive method for detection of Shiga-like toxin-producing Escherichia coli in ground beef using the polymerase chain reaction. Appl Environ Microbiol (1992) 3.14
Public health. Responding to market failures in tuberculosis control. Science (2001) 3.12
Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow. Immunity (2000) 2.96
Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins. J Biol Chem (1989) 2.89
Max: functional domains and interaction with c-Myc. Genes Dev (1992) 2.88
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
Etiology and outcome for 295 patients with acute liver failure in the United States. Liver Transpl Surg (1999) 2.79
Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein. Nature (1989) 2.70
c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF. Cell (1985) 2.69
NIAID Mycoses Study Group Multicenter Trial of Oral Itraconazole Therapy for Invasive Aspergillosis. Am J Med (1994) 2.60
Inactivation of the Porphyromonas gingivalis fimA gene blocks periodontal damage in gnotobiotic rats. J Bacteriol (1994) 2.59
Relationship between serum concentrations of persistent organic pollutants and the prevalence of metabolic syndrome among non-diabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002. Diabetologia (2007) 2.52
Fungal infections in patients with acute leukemia. Am J Med (1982) 2.43
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. Biochim Biophys Acta (2001) 2.41
A randomized, double-blind trial of nystatin therapy for the candidiasis hypersensitivity syndrome. N Engl J Med (1990) 2.39
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
The Drosophila RAD21 cohesin persists at the centromere region in mitosis. Curr Biol (2000) 2.29
Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding gene. Proc Natl Acad Sci U S A (1991) 2.26
The impact of culture isolation of Aspergillus species: a hospital-based survey of aspergillosis. Clin Infect Dis (2001) 2.25
Colonic necrosis with Kayexalate-sorbitol enemas after renal transplantation. Ann Intern Med (1989) 2.24
Male circumcision: a South Korean perspective. BJU Int (1999) 2.24
The clinical outcome of abdominoplasty performed under conscious sedation: increased use of fentanyl correlated with longer stay in outpatient unit. Plast Reconstr Surg (1999) 2.18
Randomised clinical trial: the effects of Helicobacter pylori eradication on glandular atrophy and intestinal metaplasia after subtotal gastrectomy for gastric cancer. Aliment Pharmacol Ther (2013) 2.17
PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase. Mol Pharmacol (1998) 2.16
Prospective multicenter surveillance study of funguria in hospitalized patients. The National Institute for Allergy and Infectious Diseases (NIAID) Mycoses Study Group. Clin Infect Dis (2000) 2.15
Using treatment failure under effective directly observed short-course chemotherapy programs to identify patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis (2000) 2.15
Rubella virus replication complexes are virus-modified lysosomes. Virology (1998) 2.07
CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. J Cell Biol (2001) 2.07
An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface. J Cell Biol (1996) 2.06
Remodelling of nasal mucosa in mild and severe persistent allergic rhinitis with special reference to the distribution of collagen, proteoglycans, and lymphatic vessels. Clin Exp Allergy (2010) 2.04
The median effective dose of dexmedetomidine for laryngeal mask airway insertion with propofol 2.0 mg/kg. Acta Anaesthesiol Scand (2014) 2.04
Single photon emission computed tomography-EEG relations in temporal lobe epilepsy. Neurology (1997) 2.03
Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc Natl Acad Sci U S A (1991) 2.03
Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression. Proc Natl Acad Sci U S A (1986) 2.00
Failure of intertrochanteric fracture fixation with a dynamic hip screw in relation to pre-operative fracture stability and osteoporosis. Int Orthop (2001) 1.95
Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides. Eur J Biochem (1991) 1.95
Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis. J Clin Invest (1998) 1.93
Relationships of S-phase fraction of breast carcinoma in relapse to duration of remission, estrogen receptor content, therapeutic responsiveness, and duration of survival. Cancer Res (1980) 1.92
Occurrence of serious adverse effects in patients receiving community-based therapy for multidrug-resistant tuberculosis. Int J Tuberc Lung Dis (2001) 1.92
Re-evaluating the treatment of nongonococcal urethritis: emphasizing emerging pathogens--a randomized clinical trial. Clin Infect Dis (2011) 1.92
Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody. J Virol (1993) 1.90
Cell-free immunity in Cecropia. A model system for antibacterial proteins. Eur J Biochem (1991) 1.90
Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease prevention. J Rheumatol (1998) 1.88
A precision measurement of the mass of the top quark. Nature (2004) 1.87
Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia. Proc Natl Acad Sci U S A (1985) 1.85
Augmented expression of normal c-myc is sufficient for cotransformation of rat embryo cells with a mutant ras gene. Mol Cell Biol (1985) 1.84
Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat. J Virol (1991) 1.84
An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. Eur J Pharmacol (1998) 1.83
The structure of human rhinovirus 16. Structure (1993) 1.83
Role for ceramide in cell cycle arrest. J Biol Chem (1995) 1.83
Aspirin use and bleeding risk after endoscopic submucosal dissection in patients with gastric neoplasms. Endoscopy (2012) 1.81
6,7-Bis(bromomethyl)-2,11,18,21,24-pentaoxatetracyclo. Acta Crystallogr C (2001) 1.79
Relationship between sonographic and pathologic findings in epidermal inclusion cysts. J Clin Ultrasound (2001) 1.77
Isolation and in vivo and in vitro antifungal activity of phenylacetic acid and sodium phenylacetate from Streptomyces humidus. Appl Environ Microbiol (2001) 1.77
Tuberculosis, poverty, and "compliance": lessons from rural Haiti. Semin Respir Infect (1991) 1.76
Somatic mutations in the kinase domain of the Met/hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas. Cancer Res (1999) 1.74
Role of ceramide in cellular senescence. J Biol Chem (1995) 1.74
Weight loss effect on inflammation and LDL oxidation in metabolically healthy but obese (MHO) individuals: low inflammation and LDL oxidation in MHO women. Int J Obes (Lond) (2006) 1.74
Intrapleural therapy for malignant pleural effusions. A randomized comparison of bleomycin and tetracycline. Chest (1991) 1.72
Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro. Exp Mol Med (2001) 1.70
Exposure and immunity to hepatitis-B virus in a liver unit. Lancet (1974) 1.68
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable. Leukemia (2003) 1.67
Myxoid liposarcoma: appearance at MR imaging with histologic correlation. Radiographics (2000) 1.67
Regulation of acetyl-CoA carboxylase. Biochem Soc Trans (2006) 1.64
Chemical methylation of inorganic mercury with methylcobalamin, a vitamin B12 analog. Science (1971) 1.63
Surveillance of cryptococcosis in Alabama, 1992-1994. Ann Epidemiol (1998) 1.62
Neonatal tolerance induced by antibody against antigen-specific receptor. Science (1974) 1.61
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem (2000) 1.60
Randomized comparison of ultrasound surveillance and clinical monitoring on arteriovenous graft outcomes. Kidney Int (2006) 1.60
Racial differences in responses to therapy with interferon in chronic hepatitis C. Consensus Interferon Study Group. Hepatology (1999) 1.59
Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer. Oncogene (1999) 1.59
Acute respiratory distress syndrome caused by miliary tuberculosis: a multicentre survey in South Korea. Int J Tuberc Lung Dis (2011) 1.58
Effect of chemotherapy on the outcome of self-expandable metallic stents in gastric cancer patients with malignant outlet obstruction. Endoscopy (2012) 1.57
Defining the structural requirements for a helix in 23 S ribosomal RNA that confers erythromycin resistance. J Mol Biol (1989) 1.57
Cutaneous and subcutaneous phaeohyphomycosis caused by Exserohilum rostratum. J Am Acad Dermatol (1993) 1.56
Bronchial anthracofibrosis (inflammatory bronchial stenosis with anthracotic pigmentation): CT findings. AJR Am J Roentgenol (2000) 1.56
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis (Edinb) (2003) 1.55
Frequent somatic mutations in serine/threonine kinase 11/Peutz-Jeghers syndrome gene in left-sided colon cancer. Cancer Res (1998) 1.55
Bowel herniation after traumatic symphysis pubis diastasis. J Orthop Trauma (2001) 1.55
A randomized trial of itraconazole in allergic bronchopulmonary aspergillosis. N Engl J Med (2000) 1.55
Purification, characterization and immunolocalization of fimbrial protein from Porphyromonas (bacteroides) gingivalis. Biochem Biophys Res Commun (1991) 1.54
Heat shock protein hsp70 protects cells from thermal stress even after deletion of its ATP-binding domain. Proc Natl Acad Sci U S A (1992) 1.54
Measurement of the forward-backward charge asymmetry in top-quark pair production. Phys Rev Lett (2008) 1.53
In vivo therapy of hepatocellular carcinoma with a tumor-specific adenoviral vector expressing interleukin-2. Hum Gene Ther (1997) 1.53