Published in Cell on June 13, 2008
Synthesis of orthogonal transcription-translation networks. Proc Natl Acad Sci U S A (2009) 1.46
Strain Dependent Genetic Networks for Antibiotic-Sensitivity in a Bacterial Pathogen with a Large Pan-Genome. PLoS Pathog (2016) 0.77
Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother (2015) 0.76
Different evolutionary modifications as a guide to rewire two-component systems. Bioinform Biol Insights (2012) 0.76
Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet (2005) 14.39
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell (2010) 14.18
A common mechanism of cellular death induced by bactericidal antibiotics. Cell (2007) 12.92
Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. PLoS Biol (2007) 10.46
Inferring genetic networks and identifying compound mode of action via expression profiling. Science (2003) 9.10
Synthetic biology: applications come of age. Nat Rev Genet (2010) 6.96
Wisdom of crowds for robust gene network inference. Nat Methods (2012) 6.91
Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. Mol Cell (2010) 5.33
Reverse engineering gene networks using singular value decomposition and robust regression. Proc Natl Acad Sci U S A (2002) 5.29
Engineered riboregulators enable post-transcriptional control of gene expression. Nat Biotechnol (2004) 5.07
Phenotypic consequences of promoter-mediated transcriptional noise. Mol Cell (2006) 4.93
Reverse engineering gene networks: integrating genetic perturbations with dynamical modeling. Proc Natl Acad Sci U S A (2003) 4.89
Programmable cells: interfacing natural and engineered gene networks. Proc Natl Acad Sci U S A (2004) 4.72
How antibiotics kill bacteria: from targets to networks. Nat Rev Microbiol (2010) 4.65
Synthetic gene networks that count. Science (2009) 4.54
Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell (2008) 4.47
Cellular decision making and biological noise: from microbes to mammals. Cell (2011) 4.44
Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature (2011) 4.06
Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli. Mol Syst Biol (2007) 3.98
Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks. Nat Biotechnol (2005) 3.89
Diversity-based, model-guided construction of synthetic gene networks with predicted functions. Nat Biotechnol (2009) 3.86
Bacterial charity work leads to population-wide resistance. Nature (2010) 3.50
Programmable bacteria detect and record an environmental signal in the mammalian gut. Proc Natl Acad Sci U S A (2014) 3.50
Vibrating insoles and balance control in elderly people. Lancet (2003) 3.48
RNA synthetic biology. Nat Biotechnol (2006) 3.37
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol (2011) 3.25
Next-generation synthetic gene networks. Nat Biotechnol (2009) 3.12
Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome. Nature (2013) 3.02
Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc Natl Acad Sci U S A (2009) 3.01
Signaling-mediated bacterial persister formation. Nat Chem Biol (2012) 2.96
Reprogramming of T cells from human peripheral blood. Cell Stem Cell (2010) 2.93
Dispersing biofilms with engineered enzymatic bacteriophage. Proc Natl Acad Sci U S A (2007) 2.87
A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell (2007) 2.83
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Mol Cell (2009) 2.74
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science (2012) 2.72
Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis. Mol Cell (2012) 2.56
Combinatorial promoter design for engineering noisy gene expression. Proc Natl Acad Sci U S A (2007) 2.40
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A (2009) 2.37
Synthetic biology moving into the clinic. Science (2011) 2.36
A synthetic biology framework for programming eukaryotic transcription functions. Cell (2012) 2.32
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma. Nat Med (2012) 2.26
Synthetic gene network for entraining and amplifying cellular oscillations. Phys Rev Lett (2002) 2.24
A network biology approach to prostate cancer. Mol Syst Biol (2007) 2.07
Noise-enhanced balance control in patients with diabetes and patients with stroke. Ann Neurol (2006) 2.06
The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell (2012) 1.96
microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma. Cancer Discov (2012) 1.94
A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol (2012) 1.93
Role of reactive oxygen species in antibiotic action and resistance. Curr Opin Microbiol (2009) 1.92
Aging, muscle activity, and balance control: physiologic changes associated with balance impairment. Gait Posture (2003) 1.84
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell (2013) 1.68
Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. Proc Natl Acad Sci U S A (2010) 1.66
Genetic switchboard for synthetic biology applications. Proc Natl Acad Sci U S A (2012) 1.60
Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nat Biotechnol (2013) 1.59
Tuning and controlling gene expression noise in synthetic gene networks. Nucleic Acids Res (2010) 1.52
Heterogeneous bacterial persisters and engineering approaches to eliminate them. Curr Opin Microbiol (2011) 1.47
Tunable signal processing in synthetic MAP kinase cascades. Cell (2011) 1.45
Antibiotics and the gut microbiota. J Clin Invest (2014) 1.39
Microbial persistence and the road to drug resistance. Cell Host Microbe (2013) 1.37
Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance. Proc Natl Acad Sci U S A (2013) 1.29
Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells. Stem Cell Reports (2013) 1.19
Fungicidal drugs induce a common oxidative-damage cellular death pathway. Cell Rep (2013) 1.19
Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proc Natl Acad Sci U S A (2010) 1.18
Iterative plug-and-play methodology for constructing and modifying synthetic gene networks. Nat Methods (2012) 1.17
Unraveling the physiological complexities of antibiotic lethality. Annu Rev Pharmacol Toxicol (2014) 1.16
Noise-enhanced balance control in older adults. Neuroreport (2002) 1.16
Functional characterization of bacterial sRNAs using a network biology approach. Proc Natl Acad Sci U S A (2011) 1.14
A network biology approach to aging in yeast. Proc Natl Acad Sci U S A (2009) 1.11
Valproic acid extends Caenorhabditis elegans lifespan. Aging Cell (2008) 1.10
Regulation of physiologic actions of LRRK2: focus on autophagy. Neurodegener Dis (2011) 1.07
Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni. Elife (2013) 1.07
Genomic approaches to deconstruct pluripotency. Annu Rev Genomics Hum Genet (2011) 1.06
Noise-enhanced vibrotactile sensitivity in older adults, patients with stroke, and patients with diabetic neuropathy. Arch Phys Med Rehabil (2002) 1.06
Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice. Sci Transl Med (2014) 1.03
Reliability and validity of the Stanford Presenteeism Scale. J Occup Environ Med (2004) 1.02
Microbial environments confound antibiotic efficacy. Nat Chem Biol (2011) 0.99
Microbiology. Antioxidant strategies to tolerate antibiotics. Science (2011) 0.95
Whole mount in situ hybridization methodology for Schistosoma mansoni. Mol Biochem Parasitol (2011) 0.95
Systems biology strikes gold. Cell (2009) 0.94
Predicting the dynamic postural control response from quiet-stance behavior in elderly adults. J Biomech (2003) 0.92
Mortality update of workers exposed to acrylonitrile in The Netherlands. J Occup Environ Med (2004) 0.92
Molecular biology. Signal processing in single cells. Science (2005) 0.91
Enhancing tactile sensation in older adults with electrical noise stimulation. Neuroreport (2002) 0.91
Incomplete follow-up in the National Cancer Institute's formaldehyde worker study and the impact on subsequent reanalyses and causal evaluations. Regul Toxicol Pharmacol (2010) 0.90
Introduction to focus issue: quantitative approaches to genetic networks. Chaos (2013) 0.89
Networking opportunities for bacteria. Cell (2008) 0.88
Plug-and-play with RNA. Nat Biotechnol (2005) 0.87
Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria. BMC Genomics (2014) 0.87
Mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin at a trichlorophenol plant in New Zealand. J Occup Environ Med (2009) 0.86
A sex-specific transcription factor controls male identity in a simultaneous hermaphrodite. Nat Commun (2013) 0.86
Differential splicing across immune system lineages. Proc Natl Acad Sci U S A (2013) 0.85
Translating the noise. Nat Genet (2002) 0.83
Elimination rates of dioxin congeners in former chlorophenol workers from Midland, Michigan. Environ Health Perspect (2012) 0.83
Size matters: network inference tackles the genome scale. Mol Syst Biol (2007) 0.83
Synthetic biology: How best to build a cell. Nature (2014) 0.82
Factors related to dioxin and furan body levels among Michigan workers. Environ Res (2007) 0.82
Low level occupational benzene exposure and hematological parameters. Chem Biol Interact (2010) 0.81
And the noise played on: stochastic gene expression and HIV-1 infection. Cell (2005) 0.81
Editorial-synthetic biology. Nucleic Acids Res (2010) 0.80
Insulating gene circuits from context by RNA processing. Nat Biotechnol (2012) 0.80
Systems biology makes it personal. Mol Cell (2009) 0.79