Published in Cancer Epidemiol Biomarkers Prev on June 01, 2008
Bioinformatics challenges for genome-wide association studies. Bioinformatics (2010) 4.45
Prioritizing candidate disease genes by network-based boosting of genome-wide association data. Genome Res (2011) 4.39
On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data. Bioinformatics (2010) 3.09
Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res (2010) 2.82
Random forests for genomic data analysis. Genomics (2012) 1.98
Association and interactions between DNA repair gene polymorphisms and adult glioma. Cancer Epidemiol Biomarkers Prev (2009) 1.51
SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization system. Nucleic Acids Res (2008) 1.42
Molecular epidemiology of primary brain tumors. Neurotherapeutics (2009) 1.22
Associations between polymorphisms in DNA repair genes and glioblastoma. Cancer Epidemiol Biomarkers Prev (2009) 1.19
Pathway analysis comparison using Crohn's disease genome wide association studies. BMC Med Genomics (2010) 1.13
Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies. Genet Epidemiol (2012) 1.13
An AUC-based permutation variable importance measure for random forests. BMC Bioinformatics (2013) 1.07
Identification of yeast transcriptional regulation networks using multivariate random forests. PLoS Comput Biol (2009) 0.95
Pathway-based identification of SNPs predictive of survival. Eur J Hum Genet (2011) 0.95
Gene-environment interactions in genome-wide association studies: current approaches and new directions. J Child Psychol Psychiatry (2013) 0.93
Association between DNA repair gene polymorphisms and risk of glioma: a systematic review and meta-analysis. Neuro Oncol (2014) 0.91
The role and clinical significance of DNA damage response and repair pathways in primary brain tumors. Cell Biosci (2013) 0.89
Associations of polymorphisms in DNA repair genes and MDR1 gene with chemotherapy response and survival of non-small cell lung cancer. PLoS One (2014) 0.88
DNA repair gene polymorphisms and tobacco smoking in the risk for colorectal adenomas. Carcinogenesis (2011) 0.87
Gene expression profiles of human glioblastomas are associated with both tumor cytogenetics and histopathology. Neuro Oncol (2010) 0.86
Association of BRCA1 functional single nucleotide polymorphisms with risk of differentiated thyroid carcinoma. Thyroid (2011) 0.85
Towards the identification of the loci of adaptive evolution. Methods Ecol Evol (2015) 0.85
A two-stage random forest-based pathway analysis method. PLoS One (2012) 0.83
The significance of Exo1 K589E polymorphism on cancer susceptibility: evidence based on a meta-analysis. PLoS One (2014) 0.81
Large scale analysis of phenotype-pathway relationships based on GWAS results. PLoS One (2014) 0.80
DNA double-strand break repair genotype and phenotype and breast cancer risk within sisters from the New York site of the Breast Cancer Family Registry (BCFR). Cancer Causes Control (2013) 0.80
Effect of EME1 exon variant Ile350Thr on risk and early onset of breast cancer in southern Chinese women. J Biomed Res (2013) 0.80
Association between three exonuclease 1 polymorphisms and cancer risks: a meta-analysis. Onco Targets Ther (2016) 0.78
Associations between Nine Polymorphisms in EXO1 and Cancer Susceptibility: A Systematic Review and Meta-Analysis of 39 Case-control Studies. Sci Rep (2016) 0.78
Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients. PLoS One (2014) 0.75
Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA-seq data analysis. Int J Mol Med (2016) 0.75
Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas. Neuro Oncol (2016) 0.75
Associations between single-nucleotide polymorphisms of human exonuclease 1 and the risk of hepatocellular carcinoma. Oncotarget (2016) 0.75
Integration of biological networks and gene expression data using Cytoscape. Nat Protoc (2007) 27.10
Predictive identification of exonic splicing enhancers in human genes. Science (2002) 16.86
DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics (2012) 9.31
Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med (2006) 7.10
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet (2009) 7.07
miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59
A travel guide to Cytoscape plugins. Nat Methods (2012) 6.53
Dental x-rays and risk of meningioma. Cancer (2012) 5.99
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat Genet (2009) 5.13
Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med (2015) 5.03
GenMAPP 2: new features and resources for pathway analysis. BMC Bioinformatics (2007) 4.97
WikiPathways: building research communities on biological pathways. Nucleic Acids Res (2011) 4.78
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell (2008) 4.70
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. J Natl Cancer Inst (2005) 4.63
Presenting and exploring biological pathways with PathVisio. BMC Bioinformatics (2008) 4.34
Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage. Cell (2012) 4.22
Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer (2008) 3.98
Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions. BMC Bioinformatics (2008) 3.89
The hypoxic response of tumors is dependent on their microenvironment. Cancer Cell (2003) 3.89
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18
Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res (2005) 3.10
DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med (2005) 3.06
The landscape of recombination in African Americans. Nature (2011) 3.06
Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution. Science (2010) 3.03
Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol (2008) 2.92
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst (2010) 2.87
The epidemiology of glioma in adults: a "state of the science" review. Neuro Oncol (2014) 2.63
The Human Epigenome Browser at Washington University. Nat Methods (2011) 2.62
Epidemiology of intracranial meningioma. Neurosurgery (2005) 2.60
Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. J Neuropathol Exp Neurol (2005) 2.58
Ventriculoperitoneal shunt complications in California: 1990 to 2000. Neurosurgery (2007) 2.55
Population- and community-based recruitment of African Americans and Latinos: the San Francisco Bay Area Lung Cancer Study. Am J Epidemiol (2003) 2.52
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet (2011) 2.43
Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. J Neuropathol Exp Neurol (2008) 2.40
Epidemiology of brain tumors. Neurol Clin (2007) 2.38
Molecular biomarker analyses using circulating tumor cells. PLoS One (2010) 2.38
Leukemia in twins: lessons in natural history. Blood (2003) 2.37
Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts. Neuro Oncol (2009) 2.23
Pilomyxoid astrocytoma: diagnosis, prognosis, and management. Neurosurg Focus (2005) 2.22
Mining biological pathways using WikiPathways web services. PLoS One (2009) 2.17
The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services. BMC Bioinformatics (2010) 2.03
Silent arteriovenous malformation hemorrhage and the recognition of "unruptured" arteriovenous malformation patients who benefit from surgical intervention. Neurosurgery (2015) 1.99
Genome-wide association study of glioma and meta-analysis. Hum Genet (2012) 1.96
Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma. Carcinogenesis (2009) 1.94
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. Proc Natl Acad Sci U S A (2010) 1.93
GO-Elite: a flexible solution for pathway and ontology over-representation. Bioinformatics (2012) 1.91
A multi-array multi-SNP genotyping algorithm for Affymetrix SNP microarrays. Bioinformatics (2007) 1.88
The emerging world of wikis. Science (2008) 1.84
Pleiotropic role for MYCN in medulloblastoma. Genes Dev (2010) 1.84
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer. Sci Signal (2011) 1.81
Blood-based profiles of DNA methylation predict the underlying distribution of cell types: a validation analysis. Epigenetics (2013) 1.79
A molecular switch underlies a human telomerase disease. Proc Natl Acad Sci U S A (2002) 1.79
History of allergies among adults with glioma and controls. Int J Cancer (2002) 1.78
Distinct germ line polymorphisms underlie glioma morphologic heterogeneity. Cancer Genet (2011) 1.77
Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers. Cancer Epidemiol Biomarkers Prev (2012) 1.76
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake. PLoS Genet (2010) 1.74
Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res (2009) 1.73
A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat Genet (2012) 1.73