Published in Nucleic Acids Res on November 04, 2008
dbNSFP: a lightweight database of human nonsynonymous SNPs and their functional predictions. Hum Mutat (2011) 6.97
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat Genet (2009) 5.13
Prioritizing candidate disease genes by network-based boosting of genome-wide association data. Genome Res (2011) 4.39
Strategies and issues in the detection of pathway enrichment in genome-wide association studies. Hum Genet (2009) 2.31
GWASdb: a database for human genetic variants identified by genome-wide association studies. Nucleic Acids Res (2011) 1.87
Analytical methods for inferring functional effects of single base pair substitutions in human cancers. Hum Genet (2009) 1.39
Identifying functional single nucleotide polymorphisms in the human CArGome. Physiol Genomics (2011) 1.11
Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans. Hum Mol Genet (2010) 0.99
SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping. BMC Bioinformatics (2010) 0.87
Statistical Optimization of Pharmacogenomics Association Studies: Key Considerations from Study Design to Analysis. Curr Pharmacogenomics Person Med (2011) 0.82
regSNPs: a strategy for prioritizing regulatory single nucleotide substitutions. Bioinformatics (2012) 0.79
Reactome from a WikiPathways Perspective. PLoS Comput Biol (2016) 0.78
Data integration workflow for search of disease driving genes and genetic variants. PLoS One (2011) 0.77
ARYANA: Aligning Reads by Yet Another Approach. BMC Bioinformatics (2014) 0.75
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52
Human non-synonymous SNPs: server and survey. Nucleic Acids Res (2002) 50.45
KEGG for linking genomes to life and the environment. Nucleic Acids Res (2007) 49.37
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res (2005) 44.08
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res (2005) 30.44
Efficiency and power in genetic association studies. Nat Genet (2005) 25.56
Aligning multiple genomic sequences with the threaded blockset aligner. Genome Res (2004) 24.52
The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res (2007) 23.13
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2007) 22.53
SNPs3D: candidate gene and SNP selection for association studies. BMC Bioinformatics (2006) 21.54
WikiPathways: pathway editing for the people. PLoS Biol (2008) 8.13
The International HapMap Project Web site. Genome Res (2005) 5.96
GenMAPP 2: new features and resources for pathway analysis. BMC Bioinformatics (2007) 4.97
LS-SNP: large-scale annotation of coding non-synonymous SNPs based on multiple information sources. Bioinformatics (2005) 3.05
PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes. Nucleic Acids Res (2006) 3.04
Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests. Cancer Epidemiol Biomarkers Prev (2008) 1.56
Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer. Cancer Epidemiol Biomarkers Prev (2008) 1.33
Using the MetaCyc pathway database and the BioCyc database collection. Curr Protoc Bioinformatics (2007) 0.97
Integration of biological networks and gene expression data using Cytoscape. Nat Protoc (2007) 27.10
MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol (2003) 20.83
Predictive identification of exonic splicing enhancers in human genes. Science (2002) 16.86
GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet (2002) 14.69
DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics (2012) 9.31
WikiPathways: pathway editing for the people. PLoS Biol (2008) 8.13
Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med (2006) 7.10
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet (2009) 7.07
miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59
Dental x-rays and risk of meningioma. Cancer (2012) 5.99
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat Genet (2009) 5.13
Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med (2015) 5.03
GenMAPP 2: new features and resources for pathway analysis. BMC Bioinformatics (2007) 4.97
WikiPathways: building research communities on biological pathways. Nucleic Acids Res (2011) 4.78
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell (2008) 4.70
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. J Natl Cancer Inst (2005) 4.63
Presenting and exploring biological pathways with PathVisio. BMC Bioinformatics (2008) 4.34
Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer (2008) 3.98
A public gene trap resource for mouse functional genomics. Nat Genet (2004) 3.96
Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions. BMC Bioinformatics (2008) 3.89
The hypoxic response of tumors is dependent on their microenvironment. Cancer Cell (2003) 3.89
Epidemiology and molecular pathology of glioma. Nat Clin Pract Neurol (2006) 3.76
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Epidemiology and etiology of meningioma. J Neurooncol (2010) 3.64
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res (2006) 3.40
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18
DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med (2005) 3.06
The landscape of recombination in African Americans. Nature (2011) 3.06
Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol (2008) 2.92
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst (2010) 2.87
Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS One (2009) 2.62
Epidemiology of intracranial meningioma. Neurosurgery (2005) 2.60
Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. J Neuropathol Exp Neurol (2005) 2.58
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A (2007) 2.56
Population- and community-based recruitment of African Americans and Latinos: the San Francisco Bay Area Lung Cancer Study. Am J Epidemiol (2003) 2.52
Interfacing silicon nanowires with mammalian cells. J Am Chem Soc (2007) 2.47
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet (2011) 2.43
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data. Nucleic Acids Res (2010) 2.41
Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma. J Neuropathol Exp Neurol (2008) 2.40
Epidemiology of brain tumors. Neurol Clin (2007) 2.38
Molecular biomarker analyses using circulating tumor cells. PLoS One (2010) 2.38
Leukemia in twins: lessons in natural history. Blood (2003) 2.37
Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts. Neuro Oncol (2009) 2.23
Pilomyxoid astrocytoma: diagnosis, prognosis, and management. Neurosurg Focus (2005) 2.22
Mining biological pathways using WikiPathways web services. PLoS One (2009) 2.17
The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services. BMC Bioinformatics (2010) 2.03
Silent arteriovenous malformation hemorrhage and the recognition of "unruptured" arteriovenous malformation patients who benefit from surgical intervention. Neurosurgery (2015) 1.99
Genome-wide association study of glioma and meta-analysis. Hum Genet (2012) 1.96
Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma. Carcinogenesis (2009) 1.94
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. Proc Natl Acad Sci U S A (2010) 1.93
GO-Elite: a flexible solution for pathway and ontology over-representation. Bioinformatics (2012) 1.91
A multi-array multi-SNP genotyping algorithm for Affymetrix SNP microarrays. Bioinformatics (2007) 1.88
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture. Dis Model Mech (2011) 1.87
Pleiotropic role for MYCN in medulloblastoma. Genes Dev (2010) 1.84
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer. Sci Signal (2011) 1.81
Blood-based profiles of DNA methylation predict the underlying distribution of cell types: a validation analysis. Epigenetics (2013) 1.79
History of allergies among adults with glioma and controls. Int J Cancer (2002) 1.78
Distinct germ line polymorphisms underlie glioma morphologic heterogeneity. Cancer Genet (2011) 1.77
Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers. Cancer Epidemiol Biomarkers Prev (2012) 1.76
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake. PLoS Genet (2010) 1.74
Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res (2009) 1.73
A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat Genet (2012) 1.73
Surgical technique of temporary arterial occlusion in the operative management of spinal hemangioblastomas. World Neurosurg (2010) 1.72
The Pathways Study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California. Cancer Causes Control (2008) 1.70
Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun (2011) 1.69
PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. Hum Pathol (2005) 1.67
Immune cell infiltrate differences in pilocytic astrocytoma and glioblastoma: evidence of distinct immunological microenvironments that reflect tumor biology. J Neurosurg (2011) 1.67
Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. Brain Pathol (2007) 1.66
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev (2012) 1.64
Long-term outcomes in patients with treated childhood hydrocephalus. J Neurosurg (2007) 1.59