Published in Proc Natl Acad Sci U S A on June 18, 2008
The DNA damage response: making it safe to play with knives. Mol Cell (2010) 16.13
RECQL5 controls transcript elongation and suppresses genome instability associated with transcription stress. Cell (2014) 2.38
Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance. Trends Biochem Sci (2008) 2.24
Roles of Werner syndrome protein in protection of genome integrity. DNA Repair (Amst) (2010) 1.82
Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation. Mol Cell (2009) 1.68
MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication. EMBO J (2009) 1.60
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature (2013) 1.57
DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes. PLoS Genet (2010) 1.47
Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation. Proc Natl Acad Sci U S A (2009) 1.35
Direct inhibition of RNA polymerase II transcription by RECQL5. J Biol Chem (2009) 1.22
Preferential repair of oxidized base damage in the transcribed genes of mammalian cells. J Biol Chem (2010) 1.22
RecQ helicases: multiple structures for multiple functions? HFSP J (2009) 1.20
Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression. Hum Mol Genet (2012) 1.18
Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. Mol Cell (2012) 1.18
Tissue-spanning redox gradient-dependent assembly of native human papillomavirus type 16 virions. J Virol (2009) 1.18
RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase. Mol Cell Biol (2010) 1.17
More complexity to the Bloom's syndrome complex. Genes Dev (2008) 1.16
DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation. Nature (2012) 1.11
RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription. Nucleic Acids Res (2010) 1.08
RecQ helicases in DNA double strand break repair and telomere maintenance. Mutat Res (2011) 1.08
Updating the CTD Story: From Tail to Epic. Genet Res Int (2011) 1.06
A role for the RNA pol II-associated PAF complex in AID-induced immune diversification. J Exp Med (2012) 1.03
The SET2-RPB1 interaction domain of human RECQ5 is important for transcription-associated genome stability. Mol Cell Biol (2011) 1.02
Stimulation of UvrD helicase by UvrAB. J Biol Chem (2009) 0.99
RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression. Nucleic Acids Res (2011) 0.98
Identification of novel α-n-methylation of CENP-B that regulates its binding to the centromeric DNA. J Proteome Res (2013) 0.98
The influenza A virus NS1 protein interacts with the nucleoprotein of viral ribonucleoprotein complexes. J Virol (2011) 0.98
Recruitment and retention dynamics of RECQL5 at DNA double strand break sites. DNA Repair (Amst) (2012) 0.94
Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion. Cell Cycle (2014) 0.92
Human RECQL5 participates in the removal of endogenous DNA damage. Mol Biol Cell (2012) 0.92
Human RECQL5beta stimulates flap endonuclease 1. Nucleic Acids Res (2010) 0.91
Replication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stability. Front Genet (2015) 0.90
Genome-wide comprehensive analysis of human helicases. Commun Integr Biol (2011) 0.90
RECQL5 plays co-operative and complementary roles with WRN syndrome helicase. Nucleic Acids Res (2012) 0.89
GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein. J Biol Chem (2011) 0.89
The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability. Nucleic Acids Res (2012) 0.88
The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis. PLoS Genet (2015) 0.88
Mutation of cancer driver MLL2 results in transcription stress and genome instability. Genes Dev (2016) 0.86
The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD. J Biol Chem (2015) 0.86
A Functional Proteomics Perspective of DBC1 as a Regulator of Transcription. J Proteomics Bioinform (2013) 0.86
The RecQ helicase RECQL5 participates in psoralen-induced interstrand cross-link repair. Carcinogenesis (2013) 0.86
Unwinding and rewinding: double faces of helicase? J Nucleic Acids (2012) 0.86
Structure and Mechanisms of SF1 DNA Helicases. Adv Exp Med Biol (2013) 0.86
msl2 mRNA is bound by free nuclear MSL complex in Drosophila melanogaster. Nucleic Acids Res (2011) 0.84
Human RECQL5: guarding the crossroads of DNA replication and transcription and providing backup capability. Crit Rev Biochem Mol Biol (2013) 0.84
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation. J Biol Chem (2015) 0.84
DNA helicases associated with genetic instability, cancer, and aging. Adv Exp Med Biol (2013) 0.83
Fcp1 dephosphorylation of the RNA polymerase II C-terminal domain is required for efficient transcription of heat shock genes. Mol Cell Biol (2012) 0.83
TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin. Nat Commun (2015) 0.83
Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5. Nat Struct Mol Biol (2013) 0.82
Transcription and recombination: when RNA meets DNA. Cold Spring Harb Perspect Biol (2014) 0.81
The role of RecQ helicases in non-homologous end-joining. Crit Rev Biochem Mol Biol (2014) 0.81
RECQ5-dependent SUMOylation of DNA topoisomerase I prevents transcription-associated genome instability. Nat Commun (2015) 0.81
Discovery of cell compartment specific protein-protein interactions using affinity purification combined with tandem mass spectrometry. J Proteome Res (2012) 0.80
Purification of a novel RECQL5-SWI/SNF-RNAPII super complex. Int J Biochem Mol Biol (2010) 0.78
Crosstalk between the H3K36me3 and H4K16ac histone epigenetic marks in DNA double-strand break repair. J Biol Chem (2017) 0.77
Scaffold attachment factor A (SAF-A) and Ku temporally regulate repair of radiation-induced clustered genome lesions. Oncotarget (2016) 0.76
Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A. Nucleic Acids Res (2016) 0.75
Chromatin changes in SMARCAL1 deficiency: A hypothesis for the gene expression alterations of Schimke immuno-osseous dysplasia. Nucleus (2016) 0.75
SIRT2 regulates nuclear envelope reassembly via ANKLE2 deacetylation. J Cell Sci (2016) 0.75
Multiomic Analysis of the UV-Induced DNA Damage Response. Cell Rep (2016) 0.75
Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res (2017) 0.75
When transcription meets recombination: a lesson from the human RECQ protein complexes. F1000 Biol Rep (2009) 0.75
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Positional cloning of the Werner's syndrome gene. Science (1996) 10.98
The Bloom's syndrome gene product is homologous to RecQ helicases. Cell (1995) 9.91
RecQ helicases: caretakers of the genome. Nat Rev Cancer (2003) 5.83
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Mol Cell (2007) 4.58
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev (2007) 4.16
A human RNA polymerase II complex associated with SRB and DNA-repair proteins. Nature (1996) 3.50
A human RNA polymerase II complex containing factors that modify chromatin structure. Mol Cell Biol (1998) 3.45
The connection between transcription and genomic instability. EMBO J (2002) 3.44
RecQ helicases: guardian angels of the DNA replication fork. Chromosoma (2008) 2.43
Impairment of replication fork progression mediates RNA polII transcription-associated recombination. EMBO J (2005) 2.32
Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers. Mol Cell Biol (2005) 2.06
Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1. Mol Cell (2007) 1.95
Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork. Nucleic Acids Res (2006) 1.84
Rothmund-thomson syndrome responsible gene, RECQL4: genomic structure and products. Genomics (1999) 1.65
RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits. Mol Cell Biol (2004) 1.46
Transcription-associated recombination is dependent on replication in Mammalian cells. Mol Cell Biol (2007) 1.45
RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination. Genes Dev (2007) 1.24
A nucleolar targeting sequence in the Werner syndrome protein resides within residues 949-1092. J Cell Sci (2002) 1.21
Multifaceted role of the Saccharomyces cerevisiae Srs2 helicase in homologous recombination regulation. Biochem Soc Trans (2005) 1.17
A human RNA polymerase II-containing complex associated with factors necessary for spliceosome assembly. J Biol Chem (2001) 1.12
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature (2005) 3.90
Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination. Mol Cell (2005) 3.16
Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide. EMBO J (2004) 2.33
Structure of the single-strand annealing domain of human RAD52 protein. Proc Natl Acad Sci U S A (2002) 2.24
RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females. J Cell Biol (2007) 1.62
MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication. EMBO J (2009) 1.60
Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4. EMBO J (2009) 1.44
Direct inhibition of RNA polymerase II transcription by RECQL5. J Biol Chem (2009) 1.22
Observation of microscale superlubricity in graphite. Phys Rev Lett (2012) 1.18
The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks. Biochemistry (2011) 1.11
Targeting cancer with a lupus autoantibody. Sci Transl Med (2012) 1.09
The SET2-RPB1 interaction domain of human RECQ5 is important for transcription-associated genome stability. Mol Cell Biol (2011) 1.02
DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator. J Biol Chem (2012) 0.88
Observation of high-speed microscale superlubricity in graphite. Phys Rev Lett (2013) 0.87
Selective anti-proliferation of HER2-positive breast cancer cells by anthocyanins identified by high-throughput screening. PLoS One (2013) 0.79
[Differentiation of adipose-derived mesenchymal stem cells after transfection with Pax6 gene]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2014) 0.75
Architectures of soft robotic locomotion enabled by simple mechanical principles. Soft Matter (2017) 0.75
Interfacial shear strengths between carbon nanotubes. Nanotechnology (2010) 0.75
Early warning of illegal development for protected areas by integrating cellular automata with neural networks. J Environ Manage (2013) 0.75