Published in Proc Natl Acad Sci U S A on June 18, 2008
A restricted population of CB1 cannabinoid receptors with neuroprotective activity. Proc Natl Acad Sci U S A (2014) 1.61
The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci (2012) 1.53
Cannabis and psychosis/schizophrenia: human studies. Eur Arch Psychiatry Clin Neurosci (2009) 1.37
Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models. Br J Pharmacol (2010) 1.33
Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci (2010) 1.26
Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. Nat Rev Neurosci (2014) 1.18
Origin, early commitment, migratory routes, and destination of cannabinoid type 1 receptor-containing interneurons. Cereb Cortex (2009) 1.17
Gone to Pot - A Review of the Association between Cannabis and Psychosis. Front Psychiatry (2014) 1.14
Differential developmental trajectories for CB1 cannabinoid receptor expression in limbic/associative and sensorimotor cortical areas. Synapse (2011) 1.13
Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway. EMBO J (2014) 1.11
Endocannabinoid signaling is required for development and critical period plasticity of the whisker map in somatosensory cortex. Neuron (2009) 1.10
Cannabis Use during Adolescent Development: Susceptibility to Psychiatric Illness. Front Psychiatry (2013) 1.09
CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling. J Biol Chem (2011) 1.09
Wiring and firing neuronal networks: endocannabinoids take center stage. Curr Opin Neurobiol (2008) 1.08
Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress. Cereb Cortex (2011) 1.07
Neurobiological consequences of maternal cannabis on human fetal development and its neuropsychiatric outcome. Eur Arch Psychiatry Clin Neurosci (2009) 1.06
Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci (2010) 1.06
Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampus. J Neurosci (2012) 1.05
The endocannabinoid system and the regulation of neural development: potential implications in psychiatric disorders. Eur Arch Psychiatry Clin Neurosci (2009) 1.04
Keep off the grass? Cannabis, cognition and addiction. Nat Rev Neurosci (2016) 1.01
Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS. Br J Pharmacol (2014) 1.00
The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling. Philos Trans R Soc Lond B Biol Sci (2012) 0.99
In vivo expression of a light-activatable potassium channel using unnatural amino acids. Neuron (2013) 0.99
Trajectory of adolescent cannabis use on addiction vulnerability. Neuropharmacology (2013) 0.98
Cannabinoid receptors CB1 and CB2 form functional heteromers in brain. J Biol Chem (2012) 0.96
Long-term consequences of adolescent cannabinoid exposure in adult psychopathology. Front Neurosci (2014) 0.96
Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation. Neuropsychopharmacology (2014) 0.95
Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain. Future Neurol (2011) 0.92
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signaling. J Biol Chem (2010) 0.92
Neuronal substrates and functional consequences of prenatal cannabis exposure. Eur Child Adolesc Psychiatry (2014) 0.92
The endocannabinoid system in normal and pathological brain ageing. Philos Trans R Soc Lond B Biol Sci (2012) 0.90
Molecular model of cannabis sensitivity in developing neuronal circuits. Trends Pharmacol Sci (2011) 0.90
Developmental trajectory of the endocannabinoid system in human dorsolateral prefrontal cortex. BMC Neurosci (2012) 0.88
Diacylglycerol lipase-alpha and -beta control neurite outgrowth in neuro-2a cells through distinct molecular mechanisms. Mol Pharmacol (2011) 0.87
Endocannabinoids via CB₁ receptors act as neurogenic niche cues during cortical development. Philos Trans R Soc Lond B Biol Sci (2012) 0.87
Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. J Neurosci (2013) 0.86
Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells. J Physiol (2012) 0.85
Individual differences in response to positive and negative stimuli: endocannabinoid-based insight on approach and avoidance behaviors. Front Syst Neurosci (2014) 0.85
Impact of Cannabis Use on the Development of Psychotic Disorders. Curr Addict Rep (2014) 0.85
Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment. Eur J Neurosci (2011) 0.84
Endocannabinoid system: emerging role from neurodevelopment to neurodegeneration. Mini Rev Med Chem (2009) 0.84
Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth. Elife (2014) 0.83
Cannabinoid receptor CB2 modulates axon guidance. PLoS One (2013) 0.83
G-protein-coupled receptors in adult neurogenesis. Pharmacol Rev (2012) 0.83
Developmental regulation of fear learning and anxiety behavior by endocannabinoids. Genes Brain Behav (2015) 0.82
Endocannabinoid system: potential novel targets for treatment of schizophrenia. Neurobiol Dis (2012) 0.82
Long-term consequences of perinatal fatty acid amino hydrolase inhibition. Br J Pharmacol (2014) 0.81
Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling. Nat Commun (2014) 0.81
Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling. Sci Rep (2013) 0.81
Marijuana, Spice 'herbal high', and early neural development: implications for rescheduling and legalization. Drug Test Anal (2012) 0.81
GPCRs in stem cell function. Prog Mol Biol Transl Sci (2013) 0.80
Cannabinoid receptor 1 signaling in embryo neurodevelopment. Birth Defects Res B Dev Reprod Toxicol (2012) 0.80
Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting. Psychopharmacology (Berl) (2011) 0.79
Prenatal corticosterone and adolescent URB597 administration modulate emotionality and CB1 receptor expression in mice. Psychopharmacology (Berl) (2013) 0.79
Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. Int J Neuropsychopharmacol (2014) 0.79
The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development. Neuropsychopharmacology (2017) 0.78
Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB1 receptors on developing cortical neurons. Proc Natl Acad Sci U S A (2015) 0.78
Activation of type 1 cannabinoid receptor (CB1R) promotes neurogenesis in murine subventricular zone cell cultures. PLoS One (2013) 0.77
Cannabinoid mitigation of neuronal morphological change important to development and learning: insight from a zebra finch model of psychopharmacology. Life Sci (2012) 0.77
Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling. Brain Sci (2015) 0.76
Differential Pharmacological Regulation of Sensorimotor Gating Deficit in CB1 Knockout Mice and Associated Neurochemical and Histological Alterations. Neuropsychopharmacology (2015) 0.76
Maternal Malnutrition in the Etiopathogenesis of Psychiatric Diseases: Role of Polyunsaturated Fatty Acids. Brain Sci (2016) 0.76
Cannabinoid signaling system: does it play a function in cell proliferation and migration, neuritic elongation and guidance and synaptogenesis during brain ontogenesis? Cell Adh Migr (2008) 0.76
Altered patterns of filopodia production in CHO cells heterologously expressing zebra finch CB(1) cannabinoid receptors. Cell Adh Migr (2012) 0.76
Developmental increase in hippocampal endocannabinoid mobilization: role of metabotropic glutamate receptor subtype 5 and phospholipase C. J Neurophysiol (2014) 0.76
Activation of Both CB1 and CB2 Endocannabinoid Receptors Is Critical for Masculinization of the Developing Medial Amygdala and Juvenile Social Play Behavior. eNeuro (2017) 0.75
Persistent inhibitory circuit defects and disrupted social behaviour following in utero exogenous cannabinoid exposure. Mol Psychiatry (2016) 0.75
Cannabinoid Receptors Modulate Neuronal Morphology and AnkyrinG Density at the Axon Initial Segment. Front Cell Neurosci (2017) 0.75
Elucidating cannabinoid biology in zebrafish (Danio rerio). Gene (2015) 0.75
Developmental Switch in Spike Timing-Dependent Plasticity and Cannabinoid-Dependent Reorganization of the Thalamocortical Projection in the Barrel Cortex. J Neurosci (2016) 0.75
A novel live cell assay to measure diacylglycerol lipase α activity. Biosci Rep (2016) 0.75
Stress and adolescent hippocampal neurogenesis: diet and exercise as cognitive modulators. Transl Psychiatry (2017) 0.75
Prenatal Ethanol Exposure Persistently Alters Endocannabinoid Signaling and Endocannabinoid-Mediated Excitatory Synaptic Plasticity in Ventral Tegmental Area Dopamine Neurons. J Neurosci (2017) 0.75
Role of the endocannabinoid system in vertebrates: Emphasis on the zebrafish model. Dev Growth Differ (2017) 0.75
The establishment of polarity by hippocampal neurons in culture. J Neurosci (1988) 8.40
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc Natl Acad Sci U S A (2001) 7.15
The expression of vesicular glutamate transporters defines two classes of excitatory synapse. Neuron (2001) 4.97
The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron (2006) 4.12
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J Cell Biol (2003) 3.60
Trk receptors: mediators of neurotrophin action. Curr Opin Neurobiol (2001) 3.40
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell (2006) 3.12
Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat. Neurotoxicology (1993) 3.00
p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes Dev (2006) 2.89
The CB1 cannabinoid receptor is the major cannabinoid receptor at excitatory presynaptic sites in the hippocampus and cerebellum. J Neurosci (2006) 2.66
Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis (2006) 2.52
Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (2007) 2.21
Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone. Proc Natl Acad Sci U S A (2005) 1.77
The emerging functions of endocannabinoid signaling during CNS development. Trends Pharmacol Sci (2007) 1.68
A century of progress in corticoneurogenesis: from silver impregnation to genetic engineering. Cereb Cortex (2006) 1.58
Cannabinoid receptor type 1 located on presynaptic terminals of principal neurons in the forebrain controls glutamatergic synaptic transmission. J Neurosci (2006) 1.48
Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice. Mol Pharmacol (2004) 1.34
The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells. J Neurosci (2006) 1.33
Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proc Natl Acad Sci U S A (2005) 1.33
Development of the first potent and specific inhibitors of endocannabinoid biosynthesis. Biochim Biophys Acta (2006) 1.31
The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation. Mol Cell Neurosci (2008) 1.08
Pyramidal neurons grow up and change their mind. Neuron (2008) 1.07
Preferential limbic expression of the cannabinoid receptor mRNA in the human fetal brain. Neuroscience (2003) 0.99
Phylogenomic and chemotaxonomic analysis of the endocannabinoid system. Brain Res Brain Res Rev (2004) 0.94
The endogenous cannabinoid system controls extinction of aversive memories. Nature (2002) 7.19
CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science (2003) 5.22
Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (2005) 5.12
Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature (2010) 5.11
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest (2005) 4.55
The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron (2006) 4.12
Pyramidal cell communication within local networks in layer 2/3 of rat neocortex. J Physiol (2003) 4.04
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science (2010) 3.97
Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin. Cell (2009) 3.80
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest (2003) 3.62
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J Cell Biol (2003) 3.60
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci (2010) 3.41
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J (2002) 3.30
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest (2009) 3.23
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci U S A (2002) 3.16
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest (2008) 3.13
Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. J Gen Physiol (2005) 2.98
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab (2008) 2.91
The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev (2005) 2.90
Activity-dependent decrease of excitability in rat hippocampal neurons through increases in I(h). Nat Neurosci (2005) 2.89
Nonpsychotropic cannabinoid receptors regulate microglial cell migration. J Neurosci (2003) 2.84
Molecular composition of the endocannabinoid system at glutamatergic synapses. J Neurosci (2006) 2.81
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci (2007) 2.78
CB2: a cannabinoid receptor with an identity crisis. Br J Pharmacol (2010) 2.74
Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia. J Clin Endocrinol Metab (2006) 2.72
Phosphorylation of Neurogenin2 specifies the migration properties and the dendritic morphology of pyramidal neurons in the neocortex. Neuron (2005) 2.70
Adult generation of glutamatergic olfactory bulb interneurons. Nat Neurosci (2009) 2.63
Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis. Neuron (2010) 2.54
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. Br J Pharmacol (2002) 2.54
The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest (2004) 2.52
Model of chemotherapy-induced myelosuppression with parameter consistency across drugs. J Clin Oncol (2002) 2.43
GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proc Natl Acad Sci U S A (2008) 2.42
Building a new conceptual framework for receptor heteromers. Nat Chem Biol (2009) 2.41
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nat Neurosci (2010) 2.37
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. Nat Med (2006) 2.34
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci (2009) 2.33
The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nat Cell Biol (2008) 2.32
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. Trends Pharmacol Sci (2009) 2.32
Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types. J Neurosci (2005) 2.32
Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation. J Neurosci (2005) 2.31
A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nat Neurosci (2005) 2.30
Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. Liver Int (2009) 2.27
Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis. Nature (2011) 2.22
Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (2007) 2.21
Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization. Invest Ophthalmol Vis Sci (2003) 2.20
Mitochondrial CB₁ receptors regulate neuronal energy metabolism. Nat Neurosci (2012) 2.15
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation (2004) 2.15
Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice. PLoS Biol (2007) 2.08
Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Dev Cell (2006) 2.06
Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. J Physiol (2005) 2.06
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Dev Cell (2009) 2.04
Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. Epilepsia (2014) 1.97
Neurogenin 2 controls cortical neuron migration through regulation of Rnd2. Nature (2008) 1.94
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity. Nat Neurosci (2009) 1.93
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell (2013) 1.92
Increased abundance of opioid receptor heteromers after chronic morphine administration. Sci Signal (2010) 1.90
Possible endocannabinoid control of colorectal cancer growth. Gastroenterology (2003) 1.89
Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels. Eur J Biochem (2004) 1.87
Coupling of cell migration with neurogenesis by proneural bHLH factors. Proc Natl Acad Sci U S A (2006) 1.87
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature (2013) 1.86
Pregnenolone can protect the brain from cannabis intoxication. Science (2014) 1.85
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. Cancer Cell (2006) 1.85
Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids. Neuron (2007) 1.85
Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol (2009) 1.85
Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq. J Gen Physiol (2004) 1.82
Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures. Neuron (2003) 1.80
JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. Br J Pharmacol (2010) 1.79
A digital atlas to characterize the mouse brain transcriptome. PLoS Comput Biol (2005) 1.78
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. Am J Physiol Heart Circ Physiol (2007) 1.77
Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling. Nat Neurosci (2009) 1.77
Dissemination of methicillin-resistant Staphylococcus aureus USA300 sequence type 8 lineage in Latin America. Clin Infect Dis (2009) 1.77
The endocannabinoid system: a general view and latest additions. Br J Pharmacol (2004) 1.77
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain (2010) 1.77