Published in Nature on July 20, 2011
Genomic imprinting: the emergence of an epigenetic paradigm. Nat Rev Genet (2011) 3.10
Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence. Nature (2013) 2.22
Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. Neuron (2013) 1.87
The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism. Cell Stem Cell (2015) 1.56
Extracellular matrix: a dynamic microenvironment for stem cell niche. Biochim Biophys Acta (2014) 1.45
Protection against de novo methylation is instrumental in maintaining parent-of-origin methylation inherited from the gametes. Mol Cell (2012) 1.36
An unbiased assessment of the role of imprinted genes in an intergenerational model of developmental programming. PLoS Genet (2012) 1.34
What does the concept of the stem cell niche really mean today? BMC Biol (2012) 1.32
A unifying hypothesis on mammalian neural stem cell properties in the adult hippocampus. Curr Opin Neurobiol (2012) 1.27
Genomic imprinting in development, growth, behavior and stem cells. Development (2014) 1.23
A survey of tissue-specific genomic imprinting in mammals. Mol Genet Genomics (2012) 1.19
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Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development. Proc Natl Acad Sci U S A (2015) 1.07
An integrative analysis of DNA methylation and RNA-Seq data for human heart, kidney and liver. BMC Syst Biol (2011) 0.98
Molecular diversity subdivides the adult forebrain neural stem cell population. Stem Cells (2014) 0.97
Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis. Nat Commun (2013) 0.96
Membrane-tethered delta-like 1 homolog (DLK1) restricts adipose tissue size by inhibiting preadipocyte proliferation. Diabetes (2012) 0.95
Mechanisms of long range silencing by imprinted macro non-coding RNAs. Curr Opin Genet Dev (2012) 0.92
Meat Science and Muscle Biology Symposium: stem cell niche and postnatal muscle growth. J Anim Sci (2011) 0.92
DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo. Cancer Lett (2011) 0.91
The endocannabinoid system in normal and pathological brain ageing. Philos Trans R Soc Lond B Biol Sci (2012) 0.90
A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation. Genome Res (2015) 0.90
Mosaic analysis with double markers reveals cell-type-specific paternal growth dominance. Cell Rep (2013) 0.89
DLK1/PREF1 regulates nutrient metabolism and protects from steatosis. Proc Natl Acad Sci U S A (2014) 0.87
Epigenetic control on cell fate choice in neural stem cells. Protein Cell (2012) 0.87
Epigenetic control of the genome-lessons from genomic imprinting. Genes (Basel) (2014) 0.87
Paternal alcohol exposure reduces alcohol drinking and increases behavioral sensitivity to alcohol selectively in male offspring. PLoS One (2014) 0.84
Genomic imprinting variations in the mouse type 3 deiodinase gene between tissues and brain regions. Mol Endocrinol (2014) 0.84
Human PPP1R26P1 functions as cis-repressive element in mouse Rb1. PLoS One (2013) 0.83
Phenotype and Stability of Neural Differentiation of Androgenetic Murine ES Cell-Derived Neural Progenitor Cells. Cell Med (2013) 0.83
Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells. Haematologica (2012) 0.83
RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers. Sci Rep (2016) 0.81
Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis. Nat Commun (2015) 0.81
Genomic imprinting of the type 3 thyroid hormone deiodinase gene: regulation and developmental implications. Biochim Biophys Acta (2012) 0.81
Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain. Elife (2015) 0.81
Parent-of-origin effects implicate epigenetic regulation of experimental autoimmune encephalomyelitis and identify imprinted Dlk1 as a novel risk gene. PLoS Genet (2014) 0.80
DLK1 is a somato-dendritic protein expressed in hypothalamic arginine-vasopressin and oxytocin neurons. PLoS One (2012) 0.80
Molecular epigenetic switches in neurodevelopment in health and disease. Front Behav Neurosci (2015) 0.80
Imprinted silencing is extended over broad chromosomal domains in mouse extra-embryonic lineages. Curr Opin Cell Biol (2013) 0.79
Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon. PLoS One (2012) 0.79
Regulation of mammary epithelial cell homeostasis by lncRNAs. Int J Biochem Cell Biol (2014) 0.79
Genomic imprinting, action, and interaction of maternal and fetal genomes. Proc Natl Acad Sci U S A (2014) 0.79
New Perspectives on Genomic Imprinting, an Essential and Multifaceted Mode of Epigenetic Control in the Developing and Adult Brain. Annu Rev Neurosci (2016) 0.78
Genomic imprinting is variably lost during reprogramming of mouse iPS cells. Stem Cell Res (2013) 0.78
Epigenetic control of neurotransmitter expression in olfactory bulb interneurons. Int J Dev Neurosci (2012) 0.78
Pituitary phenotypes of mice lacking the notch signalling ligand delta-like 1 homologue. J Neuroendocrinol (2013) 0.78
Bone morphogenetic protein dominantly suppresses epidermal growth factor-induced proliferative expansion of adult forebrain neural precursors. Front Neurosci (2015) 0.78
The Role of Astrocytes in the Generation, Migration, and Integration of New Neurons in the Adult Olfactory Bulb. Front Neurosci (2016) 0.77
Genomic Imprinting: A New Epigenetic Perspective of Sleep Regulation. PLoS Genet (2016) 0.77
Epigenetic regulation of stemness maintenance in the neurogenic niches. World J Stem Cells (2015) 0.77
Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice. Sci Rep (2017) 0.76
Astroglial β-Arrestin1-mediated Nuclear Signaling Regulates the Expansion of Neural Precursor Cells in Adult Hippocampus. Sci Rep (2015) 0.76
Parent-of-Origin DNA Methylation Dynamics during Mouse Development. Cell Rep (2016) 0.76
Non-germ Line Restoration of Genomic Imprinting for a Small Subset of Imprinted Genes in Ubiquitin-like PHD and RING Finger Domain-Containing 1 (Uhrf1) Null Mouse Embryonic Stem Cells. J Biol Chem (2015) 0.76
Imprinted Zac1 in neural stem cells. World J Stem Cells (2015) 0.76
Known unknowns for allele-specific expression and genomic imprinting effects. F1000Prime Rep (2014) 0.76
A mosaic world: puzzles revealed by adult neural stem cell heterogeneity. Wiley Interdiscip Rev Dev Biol (2016) 0.76
Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. Int J Obes (Lond) (2015) 0.76
Stem cells: a niche role for DLK1. Nat Rev Neurosci (2011) 0.75
Conditional Knockout of Breast Carcinoma Amplified Sequence 2 (BCAS2) in Mouse Forebrain Causes Dendritic Malformation via β-catenin. Sci Rep (2016) 0.75
DNA Methylation of Regulatory Regions of Imprinted Genes at Birth and Its Relation to Infant Temperament. Genet Epigenet (2016) 0.75
Anatomical Involvement of the Subventricular Zone Predicts Poor Survival Outcome in Low-Grade Astrocytomas. PLoS One (2016) 0.75
Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice. J Biol Chem (2014) 0.75
Epigenetic Modulators of Monocytic Function: Implication for Steady State and Disease in the CNS. Front Immunol (2016) 0.75
Neuroscience: Imprinting in the brain. Nature (2011) 0.75
Wnt signalling regulates adult hippocampal neurogenesis. Nature (2005) 6.66
Astroglia induce neurogenesis from adult neural stem cells. Nature (2002) 6.41
A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints. Dev Cell (2008) 4.80
The glial identity of neural stem cells. Nat Neurosci (2003) 4.72
Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol Cell Biol (1996) 4.26
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet (2003) 4.25
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell (2009) 3.37
p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. Genes Dev (2005) 3.08
The Dlk1 and Gtl2 genes are linked and reciprocally imprinted. Genes Dev (2000) 2.68
Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity. Mol Cell Biol (2002) 2.57
Epigenetic analysis of the Dlk1-Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparison with Igf2-H19. Hum Mol Genet (2002) 2.33
Origin and function of olfactory bulb interneuron diversity. Trends Neurosci (2008) 2.25
Delta-like and gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12. Curr Biol (2000) 2.19
Postnatal development of radial glia and the ventricular zone (VZ): a continuum of the neural stem cell compartment. Cereb Cortex (2003) 1.96
Brain micro-ecologies: neural stem cell niches in the adult mammalian brain. Philos Trans R Soc Lond B Biol Sci (2008) 1.91
Regulation of human skeletal stem cells differentiation by Dlk1/Pref-1. J Bone Miner Res (2004) 1.79
The subventricular zone en-face: wholemount staining and ependymal flow. J Vis Exp (2010) 1.70
Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J (2005) 1.68
Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone. Nat Neurosci (2009) 1.64
Adult neural stem cells in the mammalian central nervous system. Cell Res (2009) 1.64
Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting. PLoS Genet (2009) 1.58
Expression of DLK1 in hematopoietic cells results in inhibition of differentiation and proliferation. Oncogene (2005) 1.25
The atypical mammalian ligand Delta-like homologue 1 (Dlk1) can regulate Notch signalling in Drosophila. BMC Dev Biol (2008) 1.24
Ectopic expression of DLK1 protein in skeletal muscle of padumnal heterozygotes causes the callipyge phenotype. Curr Biol (2004) 1.24
Dlk1 influences differentiation and function of B lymphocytes. Stem Cells Dev (2008) 1.17
A combined ex/in vivo assay to detect effects of exogenously added factors in neural stem cells. Nat Protoc (2007) 1.12
Delta-like 1 participates in the specification of ventral midbrain progenitor derived dopaminergic neurons. J Neurochem (2007) 0.98
Different astroglia permissivity controls the migration of olfactory bulb interneuron precursors. Glia (2010) 0.95
Humoral and contact interactions in astroglia/stem cell co-cultures in the course of glia-induced neurogenesis. Glia (2005) 0.91
Midbrain expression of Delta-like 1 homologue is regulated by GDNF and is associated with dopaminergic differentiation. Exp Neurol (2007) 0.88
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin. Science (2008) 8.45
Parental origin of sequence variants associated with complex diseases. Nature (2009) 7.21
A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res (2004) 5.77
Mechanisms regulating imprinted genes in clusters. Curr Opin Cell Biol (2007) 5.49
A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints. Dev Cell (2008) 4.80
Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene. Nat Genet (2003) 4.68
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet (2003) 4.25
The External RNA Controls Consortium: a progress report. Nat Methods (2005) 4.24
SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell (2006) 4.01
Satb2 regulates callosal projection neuron identity in the developing cerebral cortex. Neuron (2008) 3.62
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J (2002) 3.30
Pigment epithelium-derived factor is a niche signal for neural stem cell renewal. Nat Neurosci (2006) 3.12
Genomic imprinting at the mammalian Dlk1-Dio3 domain. Trends Genet (2008) 2.92
Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell (2010) 2.75
Adult generation of glutamatergic olfactory bulb interneurons. Nat Neurosci (2009) 2.63
Mammalian genomic imprinting. Cold Spring Harb Perspect Biol (2011) 2.59
Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region. Hum Mol Genet (2002) 2.55
Epigenetic analysis of the Dlk1-Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparison with Igf2-H19. Hum Mol Genet (2002) 2.33
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Ann Neurol (2014) 2.33
The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nat Cell Biol (2008) 2.32
A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nat Neurosci (2005) 2.30
Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor. J Biol Chem (2006) 2.28
Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes. Nat Genet (2008) 2.16
The evolution of the DLK1-DIO3 imprinted domain in mammals. PLoS Biol (2008) 2.05
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Dev Cell (2009) 2.04
Developmental dynamics of the definitive mouse placenta assessed by stereology. Biol Reprod (2004) 1.95
Neurogenin 2 controls cortical neuron migration through regulation of Rnd2. Nature (2008) 1.94
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity. Nat Neurosci (2009) 1.93
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell (2013) 1.92
Coupling of cell migration with neurogenesis by proneural bHLH factors. Proc Natl Acad Sci U S A (2006) 1.87
Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice. Diabetes (2008) 1.86
Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol (2009) 1.85
Epigenetics: perceptive enzymes. Nature (2007) 1.71
Ascl1 genetics reveals insights into cerebellum local circuit assembly. J Neurosci (2011) 1.70
The IG-DMR and the MEG3-DMR at human chromosome 14q32.2: hierarchical interaction and distinct functional properties as imprinting control centers. PLoS Genet (2010) 1.66
The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord. Genes Dev (2005) 1.66
Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity. J Immunol (2006) 1.65
Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone. Nat Neurosci (2009) 1.64
Epigenetic status of human embryonic stem cells. Nat Genet (2005) 1.64
Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life. Mol Cell Biol (2007) 1.63
High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12. Genomics (2005) 1.60
Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting. PLoS Genet (2009) 1.58
dlk acts as a negative regulator of Notch1 activation through interactions with specific EGF-like repeats. Exp Cell Res (2004) 1.57
Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev Cell (2007) 1.56
Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region. Development (2006) 1.55
Status of genomic imprinting in human embryonic stem cells as revealed by a large cohort of independently derived and maintained lines. Hum Mol Genet (2007) 1.55
A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev (2008) 1.54
Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor. Nat Neurosci (2009) 1.54
Genomic imprinting, growth control and the allocation of nutritional resources: consequences for postnatal life. Curr Opin Endocrinol Diabetes Obes (2007) 1.54
The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis. Cardiovasc Res (2011) 1.48
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proc Natl Acad Sci U S A (2008) 1.47
Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1. J Biol Chem (2005) 1.46
Fast synaptic inhibition in spinal sensory processing and pain control. Physiol Rev (2012) 1.45
Epigenetic regulation of the neural transcriptome: the meaning of the marks. Nat Neurosci (2010) 1.44
Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis. Development (2011) 1.42
Mutation in folate metabolism causes epigenetic instability and transgenerational effects on development. Cell (2013) 1.42
Genomic imprinting contributes to thyroid hormone metabolism in the mouse embryo. Curr Biol (2002) 1.40
Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity. Eur J Immunol (2009) 1.39
BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1. Mol Cell Biol (2004) 1.38
microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons. Nat Neurosci (2012) 1.36
The EGF-like protein dlk1 inhibits notch signaling and potentiates adipogenesis of mesenchymal cells. J Mol Biol (2006) 1.36
Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues. In Vitro Cell Dev Biol Anim (2010) 1.35
An unbiased assessment of the role of imprinted genes in an intergenerational model of developmental programming. PLoS Genet (2012) 1.34
Sequential roles for Mash1 and Ngn2 in the generation of dorsal spinal cord interneurons. Development (2005) 1.34
Erbb2 regulates neuromuscular synapse formation and is essential for muscle spindle development. Development (2003) 1.33
Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression. Cell Stem Cell (2012) 1.33
Transgenerational epigenetic inheritance: how important is it? Nat Rev Genet (2013) 1.32
Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis. J Neurosci (2009) 1.31
High-frequency generation of viable mice from engineered bi-maternal embryos. Nat Biotechnol (2007) 1.28
Restricted co-expression of Dlk1 and the reciprocally imprinted non-coding RNA, Gtl2: implications for cis-acting control. Dev Biol (2007) 1.28
Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells. Development (2004) 1.25
Uniparental disomy and human disease: an overview. Am J Med Genet C Semin Med Genet (2010) 1.25
The atypical mammalian ligand Delta-like homologue 1 (Dlk1) can regulate Notch signalling in Drosophila. BMC Dev Biol (2008) 1.24
Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity. Medicine (Baltimore) (2008) 1.22
Amplification of progenitors in the mammalian telencephalon includes a new radial glial cell type. Nat Commun (2013) 1.19
The evolution of imprinting: chromosomal mapping of orthologues of mammalian imprinted domains in monotreme and marsupial mammals. BMC Evol Biol (2007) 1.19
Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis. PLoS One (2009) 1.19
dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development. Development (2006) 1.18
Dlk1 influences differentiation and function of B lymphocytes. Stem Cells Dev (2008) 1.17
dlk1/FA1 regulates the function of human bone marrow mesenchymal stem cells by modulating gene expression of pro-inflammatory cytokines and immune response-related factors. J Biol Chem (2006) 1.17
Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest. FASEB J (2011) 1.15
A small family of sushi-class retrotransposon-derived genes in mammals and their relation to genomic imprinting. J Mol Evol (2005) 1.14
Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus. Dev Biol (2010) 1.11
Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies. Proc Natl Acad Sci U S A (2004) 1.11
Imprinted gene dosage is critical for the transition to independent life. Cell Metab (2012) 1.10
Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation. Proc Natl Acad Sci U S A (2010) 1.10
Genomic imprinting. Curr Biol (2004) 1.08
Imprinted X inactivation and reprogramming in the preimplantation mouse embryo. Hum Mol Genet (2005) 1.07
An obesogenic diet during mouse pregnancy modifies maternal nutrient partitioning and the fetal growth trajectory. FASEB J (2013) 1.05
Distinguishing epigenetic marks of developmental and imprinting regulation. Epigenetics Chromatin (2010) 1.04
Epigenetic reprogramming: is deamination key to active DNA demethylation? Reproduction (2011) 1.03
Molecular mechanisms regulating phenotypic outcome in paternal and maternal uniparental disomy for chromosome 14. Epigenetics (2008) 1.03
Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev (2009) 1.03
DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation. BMC Genomics (2013) 1.02