Published in PLoS Genet on March 17, 2011
Chromatin regulation: how complex does it get? Epigenetics (2014) 0.96
Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes. PLoS Genet (2012) 0.94
Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2. Genome Res (2014) 0.85
The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition. J Biol Chem (2013) 0.84
MBTD1 is associated with Pr-Set7 to stabilize H4K20me1 in mouse oocyte meiotic maturation. Cell Cycle (2013) 0.83
Implicating SCF complexes in organogenesis in Caenorhabditis elegans. Genetics (2013) 0.81
Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man. EMBO Rep (2016) 0.79
Transcriptional regulation of gene expression in C. elegans. WormBook (2013) 0.79
Histone methylation restrains the expression of subtype-specific genes during terminal neuronal differentiation in Caenorhabditis elegans. PLoS Genet (2013) 0.77
A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombination. PLoS Genet (2013) 0.76
A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress. Elife (2017) 0.75
Mechanism of chromatin segregation to the nuclear periphery in C. elegans embryos. Worm (2016) 0.75
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
Chromatin modifications and their function. Cell (2007) 55.98
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem (1996) 45.70
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell (2001) 11.39
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Mol Cell (2003) 11.33
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat Struct Mol Biol (2007) 10.98
DNA transformation. Methods Cell Biol (1995) 9.27
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev (2002) 8.78
Histone and chromatin cross-talk. Curr Opin Cell Biol (2003) 8.69
Multivalent engagement of chromatin modifications by linked binding modules. Nat Rev Mol Cell Biol (2007) 8.14
Differential chromatin marking of introns and expressed exons by H3K36me3. Nat Genet (2009) 8.11
Maintenance of C. elegans. WormBook (2006) 7.91
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev (2003) 7.91
Genome-wide RNAi screening in Caenorhabditis elegans. Methods (2003) 7.83
Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell (2003) 6.44
Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell (2005) 5.96
Histones: annotating chromatin. Annu Rev Genet (2009) 5.93
Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans. Genetics (1985) 5.83
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J (2002) 5.70
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev (2004) 5.23
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nat Genet (2009) 4.52
Basic culture methods. Methods Cell Biol (1995) 3.87
L3MBTL1, a histone-methylation-dependent chromatin lock. Cell (2007) 3.70
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Genes Dev (2006) 3.49
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Mol Cell (2003) 2.97
The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways. Genetics (1989) 2.89
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev (2003) 2.76
Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger. Mol Cell (2007) 2.47
Maternal expression of genes that regulate the bithorax complex of Drosophila melanogaster. Dev Biol (1986) 2.16
L3MBTL1 recognition of mono- and dimethylated histones. Nat Struct Mol Biol (2007) 2.12
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1. Oncogene (2008) 1.90
Mechanisms of transcriptional repression by histone lysine methylation. Int J Dev Biol (2009) 1.82
The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6). J Biol Chem (2003) 1.73
Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans. EMBO J (2005) 1.69
SynMuv genes redundantly inhibit lin-3/EGF expression to prevent inappropriate vulval induction in C. elegans. Dev Cell (2006) 1.61
Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets. Structure (2003) 1.56
The Drosophila Polycomb group gene Sex comb on midleg (Scm) encodes a zinc finger protein with similarity to polyhomeotic protein. Development (1996) 1.54
Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Development (2007) 1.52
A heterochromatin protein 1 homologue in Caenorhabditis elegans acts in germline and vulval development. EMBO Rep (2002) 1.49
MBT domain proteins in development and disease. Semin Cell Dev Biol (2009) 1.49
Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt. EMBO J (2009) 1.42
Expression and properties of wild-type and mutant forms of the Drosophila sex comb on midleg (SCM) repressor protein. Genetics (1998) 1.41
The SynMuv genes of Caenorhabditis elegans in vulval development and beyond. Dev Biol (2007) 1.41
The Drosophila melanogaster tumor suppressor gene lethal(3)malignant brain tumor encodes a proline-rich protein with a novel zinc finger. Mech Dev (1995) 1.39
Crystal structure of the malignant brain tumor (MBT) repeats in Sex Comb on Midleg-like 2 (SCML2). J Biol Chem (2003) 1.37
Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg. EMBO Rep (2007) 1.36
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Nucleic Acids Res (2009) 1.32
A temperature-sensitive brain tumor suppressor mutation of Drosophila melanogaster: developmental studies and molecular localization of the gene. Mech Dev (1993) 1.30
Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ line. PLoS Genet (2010) 1.22
l(3)malignant brain tumor and three novel genes are required for Drosophila germ-cell formation. Genetics (2003) 1.20
Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. Development (2007) 1.16
The C. elegans HP1 homologue HPL-2 and the LIN-13 zinc finger protein form a complex implicated in vulval development. Dev Biol (2006) 1.10
The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine. J Mol Biol (2008) 1.07
Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice. J Biol Chem (2010) 1.06
Unique and redundant functions of C. elegans HP1 proteins in post-embryonic development. Dev Biol (2006) 1.05
Structural studies of a four-MBT repeat protein MBTD1. PLoS One (2009) 1.03
Impaired maturation of myeloid progenitors in mice lacking novel Polycomb group protein MBT-1. EMBO J (2005) 1.02
CLLD8/KMT1F is a lysine methyltransferase that is important for chromosome segregation. J Biol Chem (2010) 1.00
Multiple levels of redundant processes inhibit Caenorhabditis elegans vulval cell fates. Genetics (2008) 0.95
Multimerization and H3K9me3 binding are required for CDYL1b heterochromatin association. J Biol Chem (2009) 0.93
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Genes Dev (2006) 3.49
Histone methylation by PRC2 is inhibited by active chromatin marks. Mol Cell (2011) 3.14
TRIM24 links a non-canonical histone signature to breast cancer. Nature (2010) 2.99
Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin. Nat Struct Mol Biol (2008) 2.87
Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger. Mol Cell (2007) 2.47
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail. Nucleic Acids Res (2010) 2.39
The nucleation and maintenance of heterochromatin by a histone deacetylase in fission yeast. Mol Cell (2005) 2.19
HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity (2003) 2.10
Control of cytomegalovirus lytic gene expression by histone acetylation. EMBO J (2002) 2.06
14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation. EMBO J (2007) 1.69
Role of histone modifications in defining chromatin structure and function. Biol Chem (2008) 1.46
Assays for the determination of structure and dynamics of the interaction of the chromodomain with histone peptides. Methods Enzymol (2004) 1.46
Molecular architecture of the human Prp19/CDC5L complex. Mol Cell Biol (2010) 1.44
Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg. EMBO Rep (2007) 1.36
Beyond the double helix: writing and reading the histone code. Novartis Found Symp (2004) 1.25
A cascade of histone modifications induces chromatin condensation in mitosis. Science (2014) 1.21
Dynamic regulation of effector protein binding to histone modifications: the biology of HP1 switching. Cell Cycle (2006) 1.16
Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events. Nat Struct Mol Biol (2012) 1.15
Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns. Mol Cell Proteomics (2011) 1.03
Heterochromatin protein 1 forms distinct complexes to direct histone deacetylation and DNA methylation. Nat Struct Mol Biol (2012) 1.02
A dual role of H4K16 acetylation in the establishment of yeast silent chromatin. EMBO J (2011) 1.00
Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patterns. Cell Cycle (2008) 0.99
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature (2013) 0.99
Measurement of mammalian histone deacetylase activity. Methods Enzymol (2004) 0.96
Methylation of lysine 9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome. J Biol Chem (2012) 0.95
Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Rep (2013) 0.94
Multimerization and H3K9me3 binding are required for CDYL1b heterochromatin association. J Biol Chem (2009) 0.93
HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats. PLoS One (2011) 0.89
Quantitative assessment of protein interaction with methyl-lysine analogues by hybrid computational and experimental approaches. ACS Chem Biol (2011) 0.89
HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in the Caenorhabditis elegans germ line. Mol Cell Biol (2009) 0.87
Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases. Mitochondrion (2013) 0.87
Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34. Angew Chem Int Ed Engl (2013) 0.86
Tip60-ing the balance in DSB repair. Nat Cell Biol (2009) 0.85
Epigenetic markers and their cross-talk. Essays Biochem (2010) 0.82
Asymmetrically modified nucleosomes expand the histone code. Nat Struct Mol Biol (2012) 0.80
Structural plasticity in human heterochromatin protein 1β. PLoS One (2013) 0.80
Analysis of phosphorylation-dependent protein-protein interactions of histone h3. ACS Chem Biol (2014) 0.78
Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1. Nucleus (2015) 0.78
Probing the acetylation code of histone H4. Proteomics (2013) 0.78
Systematic analysis of histone modification readout. Mol Biosyst (2012) 0.77
Molecular epigenetics: connecting human biology and disease with little marks. Chembiochem (2011) 0.75