Transcriptome profiling of hippocampal CA1 after early-life seizure-induced preconditioning may elucidate new genetic therapies for epilepsy.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 4354696)

Published in Eur J Neurosci on April 04, 2013

Authors

L K Friedman1, J Mancuso, A Patel, V Kudur, J R Leheste, S Iacobas, J Botta, D A Iacobas, D C Spray

Author Affiliations

1: Basic Sciences, Cell Biology & Anatomy, New York Medical College, 50 Dana Rd, Valhalla, NY 10595, USA. Linda_Friedman@nymc.edu

Articles cited by this

Cell death: critical control points. Cell (2004) 22.56

Caspases: the executioners of apoptosis. Biochem J (1997) 11.99

Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest (2005) 8.45

The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem J (2004) 4.85

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci U S A (1995) 4.22

Molecular diversity of the NMDA receptor channel. Nature (1992) 3.76

Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell Mol Life Sci (2004) 3.01

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron (1994) 2.84

Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway. Cell Death Differ (2009) 2.63

Interleukin-6-induced protection in hyperoxic acute lung injury. Am J Respir Cell Mol Biol (2000) 2.03

Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice. Brain Res Mol Brain Res (1994) 1.90

Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy. J Neurosci (2006) 1.88

AChE-stained horizontal sections of the rat brain in stereotaxic coordinates. J Neurosci Methods (1980) 1.74

Hypothermia increases interleukin-6 and interleukin-10 in juvenile endotoxemic mice. Pediatr Crit Care Med (2010) 1.60

Susceptibility of immature and adult brains to seizure effects. Lancet Neurol (2004) 1.55

'Ischemic tolerance' phenomenon detected in various brain regions. Brain Res (1991) 1.51

Cellular injury and neuroinflammation in children with chronic intractable epilepsy. J Neuroinflammation (2009) 1.30

Regulation of the genes encoding interleukin-6, its receptor, and gp130 in the rat brain in response to the immune activator lipopolysaccharide and the proinflammatory cytokine interleukin-1beta. J Neurochem (1997) 1.26

Neuronal Ca2+ stores: activation and function. Trends Neurosci (1995) 1.26

Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiol Dis (2008) 1.16

Sensitivity of the brain transcriptome to connexin ablation. Biochim Biophys Acta (2004) 1.14

Overexpression of Bcl-2 prevents neomycin-induced hair cell death and caspase-9 activation in the adult mouse utricle in vitro. J Neurobiol (2004) 1.12

Similar transcriptomic alterations in Cx43 knockdown and knockout astrocytes. Cell Commun Adhes (2008) 1.07

Gene expression changes associated with myocarditis and fibrosis in hearts of mice with chronic chagasic cardiomyopathy. J Infect Dis (2010) 1.04

Hypoxia-induced ischemic tolerance in neonatal rat brain involves enhanced ERK1/2 signaling. J Neurochem (2004) 1.03

Quantitative transcriptional neuroanatomy of the rat hippocampus: evidence for wide-ranging, pathway-specific heterogeneity among three principal cell layers. Hippocampus (2009) 1.03

Resveratrol protects against neurotoxicity induced by kainic acid. Neurochem Res (2004) 1.02

Microarray profile of seizure damage-refractory hippocampal CA3 in a mouse model of epileptic preconditioning. Neuroscience (2007) 1.01

Suppression of hippocampal neurogenesis is associated with developmental stage, number of perinatal seizure episodes, and glucocorticosteroid level. Exp Neurol (2003) 0.99

Electroconvulsive shock exposure prevents neuronal apoptosis after kainic acid-evoked status epilepticus. Brain Res Mol Brain Res (2001) 0.97

Pathway and gene ontology based analysis of gene expression in a rat model of cerebral ischemic tolerance. Brain Res (2007) 0.95

Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats. PLoS One (2010) 0.95

Hypoxic preconditioning up-regulates glucose transport activity and glucose transporter (GLUT1 and GLUT3) gene expression after acute anoxic exposure in the cultured rat hippocampal neurons and astrocytes. Brain Res (2008) 0.94

Organizational principles of the connexin-related brain transcriptome. J Membr Biol (2007) 0.94

Lipopolysaccharide-induced ischemic tolerance is associated with increased levels of ceramide in brain and in plasma. Brain Res (2001) 0.94

Bcl-2 overexpression prevents calcium overload and subsequent apoptosis in dystrophic myotubes. Biochem J (2006) 0.94

Gene expression changes after seizure preconditioning in the three major hippocampal cell layers. Neurobiol Dis (2007) 0.93

Dantrolene protects neurons against kainic acid induced apoptosis in vitro and in vivo. J Cell Mol Med (2003) 0.91

Hippocampal kindling protects several structures from the neuronal damage resulting from kainic acid-induced status epilepticus. Brain Res (1994) 0.91

Neonatal exposure to lipopolysaccharide enhances vulnerability of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life. Neurobiol Dis (2011) 0.89

Overexpression of Bcl-2 or Bcl-xL prevents spiral ganglion neuron death and inhibits neurite growth. Dev Neurobiol (2007) 0.88

Transcriptomic signatures of alterations in a myoblast cell line infected with four distinct strains of Trypanosoma cruzi. Am J Trop Med Hyg (2010) 0.88

Intracellular cytokine production by fetal and adult monocytes. J Pediatr Surg (2001) 0.84

A short episode of seizure activity protects from status epilepticus-induced neuronal damage in rat brain. Brain Res (1998) 0.84

Involvement of extracellular regulated kinase and p38 kinase in hippocampal seizure tolerance. J Neurosci Res (2005) 0.83

Common patterns of bcl-2 family gene expression in two traumatic brain injury models. Neurotox Res (2004) 0.83

Bcl-2 over-expression promotes genomic instability by inhibiting apoptosis of cells exposed to hydrogen peroxide. Carcinogenesis (2007) 0.81

Postnatal development of lipopolysaccharide-induced inflammatory response in the brain. Inflamm Res (2010) 0.81

In vivo neuroprotective role of NMDA receptors against kainate-induced excitotoxicity in murine hippocampal pyramidal neurons. J Neurochem (2003) 0.81

Early exposure of cultured hippocampal neurons to excitatory amino acids protects from later excitotoxicity. Int J Dev Neurosci (2009) 0.81

Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia. Brain Res (1996) 0.80

Glutamatergic and morphological alterations associated with early life seizure-induced preconditioning in young rats. Eur J Neurosci (2010) 0.80

Calcium: a role for neuroprotection and sustained adaptation. Mol Interv (2006) 0.80

Maturational effects of single and multiple early-life seizures on AMPA receptors in prepubescent hippocampus. Dev Neurosci (2007) 0.80

Astrocyte activation and memory impairment in the repetitive febrile seizures model. Epilepsy Res (2009) 0.80

Perinatal seizures preferentially protect CA1 neurons from seizure-induced damage in prepubescent rats. Seizure (2005) 0.79

Preconditioning reduces hypoxia-evoked alterations in glutamatergic Ca2+ signaling in rat cortex. Acta Neurobiol Exp (Wars) (2008) 0.79

A new model for the study of high-K(+)-induced preconditioning in cultured neurones: role of N-methyl-d-aspartate and alpha7-nicotinic acetylcholine receptors. J Neurosci Methods (2008) 0.79

Astrocyte proximity modulates the myelination gene fabric of oligodendrocytes. Neuron Glia Biol (2011) 0.79

Age- and region-dependent patterns of Ca2+ accumulations following status epilepticus. Int J Dev Neurosci (2008) 0.78

Ischemic postconditioning in the rat hippocampus: mapping of proteins involved in reversal of delayed neuronal death. Arch Ital Biol (2010) 0.78

Reactive astrocytes in the kainic acid-damage hippocampus have the phenotypic features of type-2 astrocytes. J Neurocytol (1993) 0.77

The decreased susceptibility to the development of in vitro kindling-like state in hippocampal CA1 slices of rats sensitive to audiogenic seizures. Neurosci Lett (1997) 0.76

[Antisense oligodeoxynucleotides of glial glutamate transporter-1 inhibits the neuro-protection of cerebral ischemic preconditioning in rats]. Sheng Li Xue Bao (2008) 0.76

Articles by these authors

(truncated to the top 100)

Difficult Airway Society Guidelines for the management of tracheal extubation. Anaesthesia (2012) 7.19

Use of the percentage of free prostate-specific antigen to enhance differentiation of prostate cancer from benign prostatic disease: a prospective multicenter clinical trial. JAMA (1998) 5.87

Gap junctions: new tools, new answers, new questions. Neuron (1991) 4.93

Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases. Int J Radiat Oncol Biol Phys (1999) 4.72

The frequency of uterine leiomyomas. Am J Clin Pathol (1990) 4.00

Equilibrium properties of a voltage-dependent junctional conductance. J Gen Physiol (1981) 3.91

ALK1 and p80 expression and chromosomal rearrangements involving 2p23 in inflammatory myofibroblastic tumor. Mod Pathol (2001) 3.55

Kinetic properties of a voltage-dependent junctional conductance. J Gen Physiol (1981) 3.33

Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey. Clin Pharmacol Ther (2012) 3.22

Randomized clinical trial of early laparoscopy in the management of acute non-specific abdominal pain. Br J Surg (1999) 3.18

Lyme arthritis in the Hunter Valley. Med J Aust (1982) 2.68

Microscopic satellitosis in patients with primary cutaneous melanoma: implications for nodal basin staging. Ann Surg Oncol (2009) 2.67

Gap junctional conductance is a simple and sensitive function of intracellular pH. Science (1981) 2.64

Cholesterol, coronary heart disease, and stroke in the Asia Pacific region. Int J Epidemiol (2003) 2.57

Contraction-induced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscle. J Biol Chem (1997) 2.54

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions. Proc Natl Acad Sci U S A (1989) 2.53

P2X7 receptor-Pannexin1 complex: pharmacology and signaling. Am J Physiol Cell Physiol (2008) 2.49

Clinical characteristics and outcome of patients with early (<2 h), intermediate (2-4 h) and late (>4 h) presentation treated by primary coronary angioplasty or thrombolytic therapy for acute myocardial infarction. Eur Heart J (2002) 2.49

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation. Cell (2001) 2.42

Physiology and pharmacology of gap junctions. Annu Rev Physiol (1985) 2.34

Differential expression of three gap junction proteins in developing and mature brain tissues. Proc Natl Acad Sci U S A (1989) 2.34

Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Diabetologia (2011) 2.28

Isolation of infectious human T-cell leukemia/lymphotropic virus type III (HTLV-III) from patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) and from healthy carriers: a study of risk groups and tissue sources. Proc Natl Acad Sci U S A (1985) 2.26

Cardiovascular risk prediction tools for populations in Asia. J Epidemiol Community Health (2007) 2.25

Fewer sore throats and a better seal: why routine manometry for laryngeal mask airways must become the standard of care. Anaesthesia (2014) 2.21

cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide. Proc Natl Acad Sci U S A (1986) 2.20

A randomised controlled trial of cognitive behaviour therapy and motivational interviewing for people with Type 1 diabetes mellitus with persistent sub-optimal glycaemic control: a Diabetes and Psychological Therapies (ADaPT) study. Health Technol Assess (2010) 2.20

Nitric oxide synthase gene polymorphisms and diabetic nephropathy. Diabetologia (2003) 2.18

Smoking, quitting, and the risk of cardiovascular disease among women and men in the Asia-Pacific region. Int J Epidemiol (2005) 2.16

Microdeletion 15q13.3: a locus with incomplete penetrance for autism, mental retardation, and psychiatric disorders. J Med Genet (2009) 2.13

Gap junction channels: distinct voltage-sensitive and -insensitive conductance states. Biophys J (1994) 1.99

Gap junctions in the brain: where, what type, how many and why? Trends Neurosci (1993) 1.97

Neutral-lipid storage disease: a new disorder of lipid metabolism. Br Med J (1975) 1.97

Functional analysis of human cardiac gap junction channel mutants. Proc Natl Acad Sci U S A (1991) 1.94

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3). Proc Natl Acad Sci U S A (2001) 1.94

Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA. Science (1991) 1.93

Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation. Circ Res (1994) 1.92

A novel and rapid whole-blood assay for D-dimer in patients with clinically suspected deep vein thrombosis. Circulation (1995) 1.90

Voltage dependence of junctional conductance in early amphibian embryos. Science (1979) 1.90

Volatile anesthetics block intercellular communication between neonatal rat myocardial cells. Circ Res (1989) 1.90

Functional properties of channels formed by the neuronal gap junction protein connexin36. J Neurosci (1999) 1.90

Mixed glioneuronal tumour of the fourth ventricle with prominent rosette formation. Neuropathol Appl Neurobiol (2006) 1.88

Some electrical and pharmacological properties of gap junctions between adult ventricular myocytes. Am J Physiol (1985) 1.88

Wnt-1 regulation of connexin43 in cardiac myocytes. J Clin Invest (2000) 1.87

Identification of a major growth factor for AIDS-Kaposi's sarcoma cells as oncostatin M. Science (1992) 1.85

Molecular characterization and functional expression of the human cardiac gap junction channel. J Cell Biol (1990) 1.81

Gap junctions between cultured astrocytes: immunocytochemical, molecular, and electrophysiological analysis. J Neurosci (1991) 1.74

Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells. Biophys J (1991) 1.71

Speed of onset of 'corner pocket supraclavicular' and infraclavicular ultrasound guided brachial plexus block: a randomised observer-blinded comparison. Anaesthesia (2009) 1.71

Gating of gap junction channels. Biophys J (1984) 1.70

Single-channel events and gating behavior of the cardiac gap junction channel. Proc Natl Acad Sci U S A (1988) 1.70

Quinine blocks specific gap junction channel subtypes. Proc Natl Acad Sci U S A (2001) 1.67

Biochemical basis for fluorouracil neurotoxicity. The role of Krebs cycle inhibition by fluoroacetate. Arch Neurol (1970) 1.64

Expression of the herpes simplex virus type 2 latency-associated transcript enhances spontaneous reactivation of genital herpes in latently infected guinea pigs. J Exp Med (1995) 1.63

Connexin43 null mice reveal that astrocytes express multiple connexins. Brain Res Brain Res Rev (2000) 1.61

How to close a gap junction channel. Efficacies and potencies of uncoupling agents. Methods Mol Biol (2001) 1.61

Hospital utilization patterns and costs for adult sickle cell patients in Illinois. Public Health Rep (1997) 1.60

Improved toluidine blue-DNA agar for detection of DNA hydrolysis by campylobacters. J Clin Microbiol (1987) 1.59

Effects of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in patients with type 2 diabetes mellitus: a randomised controlled trial. Diabetologia (2009) 1.59

Isolated liver gap junctions: gating of transjunctional currents is similar to that in intact pairs of rat hepatocytes. Proc Natl Acad Sci U S A (1986) 1.57

The relationship between heparin level and activated clotting time in the adult cardiac surgery population. Perfusion (2009) 1.57

Thorough QT study with recommended and supratherapeutic doses of tolterodine. Clin Pharmacol Ther (2007) 1.57

Reduction of gap junctional conductance by microinjection of antibodies against the 27-kDa liver gap junction polypeptide. Proc Natl Acad Sci U S A (1985) 1.56

Transtracheal jet ventilation in 50 patients with severe airway compromise and stridor. Br J Anaesth (2010) 1.56

Intercellular communication in spinal cord astrocytes: fine tuning between gap junctions and P2 nucleotide receptors in calcium wave propagation. J Neurosci (2000) 1.56

A bacterial basic region leucine zipper histidine kinase regulating toluene degradation. Proc Natl Acad Sci U S A (1997) 1.55

Serotyping scheme for Staphylococcus aureus isolated from cows with mastitis. Am J Vet Res (1998) 1.55

Localization of impalpable breast lesions--a surgical approach. Eur J Surg Oncol (1996) 1.54

A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate. Ann Rheum Dis (2004) 1.53

A prospective, randomized, placebo controlled, double-blind study of pelvic electromagnetic therapy for the treatment of chronic pelvic pain syndrome with 1 year of followup. J Urol (2005) 1.53

Activation of a voltage-insensitive conductance by inward calcium current. Nature (1975) 1.53

Use of antibiotic prophylaxis in elective inguinal hernia repair in adults in London and south-east England: a cross-sectional survey. Hernia (2013) 1.50

Selective recruitment of polarized T cells expressing CCR5 and CXCR3 to the inflamed joints of children with juvenile idiopathic arthritis. Arthritis Rheum (2000) 1.50

22q13.3 deletion syndrome: clinical and molecular analysis using array CGH. Am J Med Genet A (2010) 1.49

Ultrasound detection of extrahepatic encapsulated bile: "biloma". AJR Am J Roentgenol (1979) 1.48

Effects of flooding amino acids on incorporation of labeled amino acids into human muscle protein. Am J Physiol (1998) 1.47

Gap junctional conductance: comparison of sensitivities to H and Ca ions. Proc Natl Acad Sci U S A (1982) 1.47

Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells. J Physiol (1999) 1.46

Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitis. Gastroenterology (1997) 1.46

Bilateral iridocorneal endothelial syndrome: case report and review of the literature. Cornea (1994) 1.45

Comparison of percent free PSA, PSA density, and age-specific PSA cutoffs for prostate cancer detection and staging. Urology (2000) 1.44

Furosemide-albumin complexes in refractory nephrotic syndrome and chronic renal failure. Nephron (1996) 1.42

Phosphorylation shifts unitary conductance and modifies voltage dependent kinetics of human connexin43 gap junction channels. Biophys J (1992) 1.41

Pollination mode in fig wasps: the predictive power of correlated traits. Proc Biol Sci (2001) 1.41

The immunogenicity, safety, and efficacy of etanercept liquid administered once weekly in patients with rheumatoid arthritis. Clin Exp Rheumatol (2007) 1.41

The effect of temperature on bougies: a photographic and manikin study. Anaesthesia (2008) 1.40

Applications of a new chemiluminometric thyrotropin assay to subnormal measurement. J Clin Endocrinol Metab (1990) 1.40

Polycystic ovaries in patients with hypogonadotropic hypogonadism: similarity of ovarian response to gonadotropin stimulation in patients with polycystic ovarian syndrome. Fertil Steril (1992) 1.40

Gap junctions in vascular tissues. Evaluating the role of intercellular communication in the modulation of vasomotor tone. Circ Res (1996) 1.40

Intra-operative frozen section analysis for suspected early-stage ovarian cancer: 11 years of Gateshead Cancer Centre experience. BJOG (2011) 1.39

Calcium and extrapyramidal symptoms. Br J Psychiatry (1988) 1.38

Permeability of gap junctions between embryonic cells of Fundulus: a reevaluation. Dev Biol (1978) 1.37

Electrophysiological properties of gap junctions between dissociated pairs of rat hepatocytes. J Cell Biol (1986) 1.37

Protective effect of epidermal growth factor in an experimental model of colitis in rats. Gastroenterology (1994) 1.37

Bronchodilator delivery in acute airflow obstruction. A meta-analysis. Arch Intern Med (1997) 1.37

Prospective observational study of acute coronary syndromes in China: practice patterns and outcomes. Heart (2007) 1.36

The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron-MR Controlled Evaluation (ADVANCE) Study. Diabetologia (2010) 1.36

Causes of death during acute asthma in children. Am J Dis Child (1974) 1.35

Predictors of ovarian reserve in young women with breast cancer. Br J Cancer (2007) 1.35

Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device. Gene Ther (2010) 1.35