Published in Biochemistry on October 02, 2008
Crossroads of PI3K and Rac pathways. Small GTPases (2015) 0.83
Convolution-based one and two component FRAP analysis: theory and application. Eur Biophys J (2009) 0.79
LI-cadherin cis-dimerizes in the plasma membrane Ca(2+) independently and forms highly dynamic trans-contacts. Cell Mol Life Sci (2012) 0.77
Role of the polycomb protein EED in the propagation of repressive histone marks. Nature (2009) 6.62
Subunit composition of mammalian transient receptor potential channels in living cells. Proc Natl Acad Sci U S A (2002) 3.88
Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells. J Exp Med (2010) 3.43
Detecting heteroplasmy from high-throughput sequencing of complete human mitochondrial DNA genomes. Am J Hum Genet (2010) 2.98
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. Nat Neurosci (2010) 2.79
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. EMBO J (2007) 2.61
A meta-analysis of structural brain abnormalities in PTSD. Neurosci Biobehav Rev (2006) 2.57
Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells. Immunity (2009) 2.17
Bevacizumab has differential and dose-dependent effects on glioma blood vessels and tumor cells. Clin Cancer Res (2011) 2.06
Reversible photobleaching of enhanced green fluorescent proteins. Biochemistry (2005) 2.05
Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma. J Cell Biol (2002) 2.03
Homo- and heteromeric assembly of TRPV channel subunits. J Cell Sci (2005) 1.93
Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth. J Biol Chem (2002) 1.91
The program for processing newly synthesized histones H3.1 and H4. Nat Struct Mol Biol (2010) 1.71
Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis. Glia (2009) 1.69
Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking. J Biol Chem (2005) 1.61
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors. Nat Commun (2012) 1.48
TRPC4 and TRPC5: receptor-operated Ca2+-permeable nonselective cation channels. Cell Calcium (2003) 1.47
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes Dev (2011) 1.43
Intraoperative lung edema monitoring by microwave reflectometry. Interact Cardiovasc Thorac Surg (2010) 1.39
Administration of perflutren contrast agents during transthoracic echocardiography is not associated with a significant increase in acute mortality risk. Cardiology (2012) 1.38
Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway. J Neurosci (2009) 1.35
Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors. J Biol Chem (2004) 1.33
The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation. Genes Dev (2013) 1.29
Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP. J Biol Chem (2008) 1.29
Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B. J Biol Chem (2006) 1.28
TRPV1 acts as proton channel to induce acidification in nociceptive neurons. J Biol Chem (2004) 1.28
Ligand-dependent differences in the internalization of endothelin A and endothelin B receptor heterodimers. J Biol Chem (2004) 1.26
Neurotransmitter properties of spinal interneurons in embryonic and larval zebrafish. J Comp Neurol (2004) 1.22
Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40. Mol Cell Endocrinol (2006) 1.22
Potentiation of TRPC5 by protons. J Biol Chem (2007) 1.22
Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival. J Physiol (2011) 1.22
Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors. FEBS Lett (2003) 1.21
Ca2+-controlled competitive diacylglycerol binding of protein kinase C isoenzymes in living cells. J Cell Biol (2002) 1.19
Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4. Genes Dev (2012) 1.19
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice. PLoS One (2010) 1.17
TRPA1 is differentially modulated by the amphipathic molecules trinitrophenol and chlorpromazine. J Biol Chem (2007) 1.15
Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2. J Cell Sci (2009) 1.14
Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma. Proc Natl Acad Sci U S A (2009) 1.13
Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones. Neuropharmacology (2005) 1.11
Receptor-operated cation channels formed by TRPC4 and TRPC5. Naunyn Schmiedebergs Arch Pharmacol (2005) 1.10
The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels. EMBO J (2006) 1.09
Pain control by CXCR2 ligands through Ca2+-regulated release of opioid peptides from polymorphonuclear cells. FASEB J (2006) 1.09
FRET-based analysis of TRPC subunit stoichiometry. Cell Calcium (2003) 1.06
Amyloid plaque formation precedes dendritic spine loss. Acta Neuropathol (2012) 1.04
Protein-protein recognition and interaction hot spots in an antigen-antibody complex: free energy decomposition identifies "efficient amino acids". Proteins (2007) 1.03
The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho. J Cell Sci (2003) 1.01
PKCalpha: a versatile key for decoding the cellular calcium toolkit. J Cell Biol (2006) 1.01
Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma. J Biol Chem (2004) 1.00
Theoretical evaluation of pK(a) in phosphoranes: implications for phosphate ester hydrolysis. J Am Chem Soc (2002) 1.00
Distinct brain networks in recognition memory share a defined region in the precuneus. Eur J Neurosci (2009) 0.99
Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing Swedish mutant β-amyloid precursor protein using 18F-florbetaben PET. J Nucl Med (2013) 0.98
Endothelin potentiates TRPV1 via ETA receptor-mediated activation of protein kinase C. Mol Pain (2007) 0.97
Novel pharmacological TRPC inhibitors block hypoxia-induced vasoconstriction. Cell Calcium (2012) 0.97
Fluorescence resonance energy transfer analysis reveals the existence of endothelin-A and endothelin-B receptor homodimers. J Cardiovasc Pharmacol (2004) 0.97
Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication. Science (2014) 0.97
Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice. PLoS One (2012) 0.97
Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication. Oncotarget (2014) 0.96
Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils. PLoS Pathog (2009) 0.95
Ultraviolet light and photosensitising agents activate TRPA1 via generation of oxidative stress. Cell Calcium (2008) 0.95
P2X7 receptors at adult neural progenitor cells of the mouse subventricular zone. Neuropharmacology (2013) 0.92
Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo. Mol Pharmacol (2013) 0.92
ERK1/2-dependent contractile protein expression in vascular smooth muscle cells. Hypertension (2003) 0.92
Clemastine potentiates the human P2X7 receptor by sensitizing it to lower ATP concentrations. J Biol Chem (2011) 0.90
Comparative analysis of procoagulatory activity of haemodialysis, haemofiltration and haemodiafiltration with a polysulfone membrane (APS) and with different modes of enoxaparin anticoagulation. Nephrol Dial Transplant (2004) 0.90
Heterodimerization of hypothalamic G-protein-coupled receptors involved in weight regulation. Obes Facts (2009) 0.88
Proline-rich sequence recognition: I. Marking GYF and WW domain assembly sites in early spliceosomal complexes. Mol Cell Proteomics (2009) 0.87
The transactivated epidermal growth factor receptor recruits Pyk2 to regulate Src kinase activity. J Biol Chem (2008) 0.87
MC4R oligomerizes independently of extracellular cysteine residues. Peptides (2005) 0.85
Real-time analysis of phospholipase C activity during different patterns of receptor-induced Ca2+ responses in HEK293 cells. Cell Calcium (2004) 0.85
In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques. Acta Neuropathol Commun (2014) 0.84
Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers. EMBO Mol Med (2012) 0.84
Cross-inhibition between native and recombinant TRPV1 and P2X(3) receptors. Pain (2009) 0.84
A heterozygous mutation in the third transmembrane domain causes a dominant-negative effect on signalling capability of the MC4R. Obes Facts (2008) 0.83
Celsior versus custodiol: early postischemic recovery after cardioplegia and ischemia at 5 degrees C. Ann Thorac Surg (2002) 0.83
Requirement of an intermediate gene expression for biphasic ERK1/2 activation in thrombin-stimulated vascular smooth muscle cells. J Biol Chem (2008) 0.82
Structure activity relationship by NMR and by computer: a comparative study. J Am Chem Soc (2002) 0.82
A triglyceride/high-density lipoprotein ratio > or = 3.5 is associated with an increased burden of coronary artery disease on cardiac catheterization. J Cardiometab Syndr (2006) 0.82
Riluzole activates TRPC5 channels independently of PLC activity. Br J Pharmacol (2014) 0.81
Relative strength of relationships of nasal congestion and ocular symptoms with sleep, mood and productivity. Curr Med Res Opin (2009) 0.80
Cellular copper import by nanocarrier systems, intracellular availability, and effects on amyloid beta peptide secretion. Biochemistry (2009) 0.80
TRPA1 is functionally expressed in melanoma cells but is not critical for impaired proliferation caused by allyl isothiocyanate or cinnamaldehyde. Naunyn Schmiedebergs Arch Pharmacol (2012) 0.79
Increase of intracellular Ca2+ by P2Y but not P2X receptors in cultured cortical multipolar neurons of the rat. J Comp Neurol (2009) 0.79
Convolution-based one and two component FRAP analysis: theory and application. Eur Biophys J (2009) 0.79
Surface expression of gpA33 is dependent on culture density and cell-cycle phase and is regulated by intracellular traffic rather than gene transcription. Cancer Biother Radiopharm (2008) 0.78
Biliary-type cytokeratin pattern in a canine isolated perfused liver transplantation model. J Surg Res (2007) 0.78
Localisation of endothelin B receptor variants to plasma membrane microdomains and its effects on downstream signalling. Mol Membr Biol (2009) 0.78
Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines as imaging agents for tau fibrils and β-amyloid plaques in Alzheimer's disease models. J Med Chem (2012) 0.77
Hemoglobin Bohr effects: atomic origin of the histidine residue contributions. Biochemistry (2013) 0.77
Natural compounds with P2X7 receptor-modulating properties. Purinergic Signal (2013) 0.77
HaCaT keratinocytes exhibit a cholesterol and plasma membrane viscosity gradient during directed migration. Exp Cell Res (2012) 0.77
Apomorphine is a bimodal modulator of TRPA1 channels. Mol Pharmacol (2012) 0.77