PubRank

John J Lemasters

Author PubWeight™ 166.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Selective degradation of mitochondria by mitophagy. Arch Biochem Biophys 2007 8.24
3 Mechanisms of hepatotoxicity. Toxicol Sci 2002 4.13
4 NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis. J Clin Invest 2003 3.69
5 Apoptosis and necrosis in the liver: a tale of two deaths? Hepatology 2006 3.52
6 Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury. Gastroenterology 2003 3.21
7 Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes. Hepatology 2004 2.92
8 Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochem Biophys Res Commun 2003 2.58
9 Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity. J Pharmacol Exp Ther 2005 2.41
10 Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy 2006 2.37
11 Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition. Hepatology 2008 2.22
12 Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? FEBS Lett 2002 2.08
13 Reactive oxygen species, but not Ca2+ overloading, trigger pH- and mitochondrial permeability transition-dependent death of adult rat myocytes after ischemia-reperfusion. Am J Physiol Heart Circ Physiol 2006 2.08
14 Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine. Toxicol Sci 2004 2.07
15 Role of mitochondrial permeability transition pores in mitochondrial autophagy. Int J Biochem Cell Biol 2004 2.01
16 Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811. Mol Pharmacol 2002 1.95
17 Nuclear translocation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury. Toxicol Sci 2006 1.94
18 Cyclophilin D as a drug target. Curr Med Chem 2003 1.87
19 c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity. Toxicol Appl Pharmacol 2010 1.84
20 Functions of autophagy in normal and diseased liver. Autophagy 2013 1.81
21 Mitophagy selectively degrades individual damaged mitochondria after photoirradiation. Antioxid Redox Signal 2011 1.79
22 Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. FASEB J 2004 1.76
23 Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells. Gastroenterology 2004 1.73
24 Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity. J Pharmacol Exp Ther 2007 1.70
25 Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. Gastroenterology 2003 1.63
26 Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy. Nat Chem Biol 2012 1.55
27 Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes. Autophagy 2009 1.49
28 Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury. Free Radic Res 2010 1.45
29 Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer. Arch Biochem Biophys 2004 1.40
30 Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation. Am J Physiol Cell Physiol 2010 1.32
31 Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury. Hepatology 2008 1.31
32 Free tubulin modulates mitochondrial membrane potential in cancer cells. Cancer Res 2010 1.23
33 Reduced-size liver transplantation in the mouse. Transplantation 2003 1.19
34 Heat shock suppresses the permeability transition in rat liver mitochondria. J Biol Chem 2003 1.18
35 Nitric oxide protects rat hepatocytes against reperfusion injury mediated by the mitochondrial permeability transition. Hepatology 2004 1.18
36 UCPs--unlikely calcium porters. Nat Cell Biol 2008 1.17
37 L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent. Curr Opin Clin Nutr Metab Care 2003 1.16
38 Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity. Toxicol Sci 2011 1.16
39 Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement. Gastroenterology 2003 1.15
40 Lysosomal iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes. Toxicol Sci 2010 1.15
41 TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells. Hepatology 2002 1.14
42 Mitochondrial permeability transition in liver ischemia and reperfusion: role of c-Jun N-terminal kinase 2. Transplantation 2008 1.13
43 Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. J Hepatol 2003 1.13
44 Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply. Transplantation 2006 1.11
45 Voltage-dependent anion channels modulate mitochondrial metabolism in cancer cells: regulation by free tubulin and erastin. J Biol Chem 2013 1.09
46 Isolated mitochondria infusion mitigates ischemia-reperfusion injury of the liver in rats: mitotracker probes and mitochondrial membrane potential. Shock 2013 1.09
47 Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats. PLoS One 2013 1.07
48 Polyphenols from Camellia sinenesis attenuate experimental cholestasis-induced liver fibrosis in rats. Am J Physiol Gastrointest Liver Physiol 2003 1.07
49 Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. PLoS One 2011 1.07
50 Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat. Transplantation 2003 1.05
51 Activation of the oxygen-sensing signal cascade prevents mitochondrial injury after mouse liver ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol 2008 1.05
52 The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes. Toxicol Sci 2010 1.05
53 Mitochondrial permeability transition in rat hepatocytes after anoxia/reoxygenation: role of Ca2+-dependent mitochondrial formation of reactive oxygen species. Am J Physiol Gastrointest Liver Physiol 2012 1.02
54 Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria. Mol Interv 2010 1.00
55 Prevention of hepatic ischemia-reperfusion injury by green tea extract. Am J Physiol Gastrointest Liver Physiol 2002 0.99
56 Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species. Biochimie 2007 0.99
57 Dephosphorylation of the Rieske iron-sulfur protein after induction of the mitochondrial permeability transition. Biochem Biophys Res Commun 2005 0.99
58 Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide. Shock 2003 0.98
59 Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes. Free Radic Biol Med 2013 0.97
60 Impact factors--a good thing? Gastroenterology 2003 0.97
61 Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols. Gastroenterology 2005 0.97
62 Autophagy in alcohol-induced liver diseases. Alcohol Clin Exp Res 2012 0.97
63 Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice. Exp Mol Pathol 2006 0.96
64 Differential effects of rapamycin on rods and cones during light-induced stress in albino mice. Invest Ophthalmol Vis Sci 2011 0.96
65 Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes. Arch Biochem Biophys 2008 0.96
66 Ischemic preconditioning prevents free radical production and mitochondrial depolarization in small-for-size rat liver grafts. Transplantation 2008 0.95
67 Warburg revisited: regulation of mitochondrial metabolism by voltage-dependent anion channels in cancer cells. J Pharmacol Exp Ther 2012 0.94
68 Inhibition of mitochondrial respiration as a source of adaphostin-induced reactive oxygen species and cytotoxicity. J Biol Chem 2007 0.94
69 NIM811 prevents mitochondrial dysfunction, attenuates liver injury, and stimulates liver regeneration after massive hepatectomy. Transplantation 2011 0.94
70 Closure of VDAC causes oxidative stress and accelerates the Ca(2+)-induced mitochondrial permeability transition in rat liver mitochondria. Arch Biochem Biophys 2010 0.94
71 NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice. J Pharmacol Exp Ther 2008 0.93
72 Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats. Free Radic Biol Med 2004 0.93
73 Role of apoptosis in acetaminophen hepatotoxicity. J Gastroenterol Hepatol 2007 0.92
74 Inhibition of transforming growth factor-beta/Smad signaling improves regeneration of small-for-size rat liver grafts. Liver Transpl 2010 0.91
75 Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. J Hepatol 2011 0.91
76 Nitric oxide: a signaling molecule against mitochondrial permeability transition- and pH-dependent cell death after reperfusion. Free Radic Biol Med 2004 0.91
77 Ethanol suppresses ureagenesis in rat hepatocytes: role of acetaldehyde. J Biol Chem 2012 0.91
78 Cyclosporin A in left ventricular remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol 2013 0.91
79 Lysosomal signaling enhances mitochondria-mediated photodynamic therapy in A431 cancer cells: role of iron. Photochem Photobiol 2012 0.90
80 Basal reactive oxygen species determine the susceptibility to apoptosis in cirrhotic hepatocytes. Free Radic Biol Med 2006 0.90
81 Mitoferrin-2-dependent mitochondrial iron uptake sensitizes human head and neck squamous carcinoma cells to photodynamic therapy. J Biol Chem 2012 0.89
82 Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter. Toxicol Appl Pharmacol 2013 0.88
83 Attenuation of acute rejection in a rat liver transplantation model by a liver-targeted dextran prodrug of methylprednisolone. Transplantation 2006 0.88
84 Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes. Biochem J 2010 0.88
85 Lipopolysaccharide-binding protein modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation. Am J Physiol Gastrointest Liver Physiol 2006 0.88
86 Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats. PLoS One 2012 0.87
87 Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. Toxicol Sci 2003 0.87
88 Graft tumor necrosis factor receptor-1 protects after mouse liver transplantation whereas host tumor necrosis factor receptor-1 promotes injury. Transplantation 2006 0.87
89 Extrahepatic cells contribute to the progenitor/stem cell response following reduced-size liver transplantation in mice. Exp Biol Med (Maywood) 2007 0.86
90 Targeted gene delivery to sinusoidal endothelial cells: DNA nanoassociate bearing hyaluronan-glycocalyx. FASEB J 2004 0.85
91 Isolated mouse liver mitochondria are devoid of glucokinase. Biochem Biophys Res Commun 2005 0.84
92 Role of free radicals in failure of fatty liver grafts caused by ethanol. Alcohol 2004 0.83
93 Signaling From Lysosomes Enhances Mitochondria-Mediated Photodynamic Therapy In Cancer Cells. Proc SPIE Int Soc Opt Eng 2009 0.81
94 Role of inducible nitric oxide synthase in mitochondrial depolarization and graft injury after transplantation of fatty livers. Free Radic Biol Med 2012 0.81
95 Lysosomal instability and cathepsin B release during acetaminophen hepatotoxicity. Basic Clin Pharmacol Toxicol 2012 0.81
96 Pinhole shifting lifetime imaging microscopy. J Biomed Opt 2009 0.81
97 Different patterns of renal cell killing after warm and cold ischemia. Ren Fail 2002 0.80
98 Role of pH in protection by low sodium against hypoxic injury in isolated perfused rat livers. J Hepatol 2005 0.80
99 Elevated levels of endothelin-1 in hepatic venous blood are associated with intrapulmonary vasodilatation in humans. Dig Dis Sci 2011 0.80
100 Carolina rinse solution minimizes kidney injury and improves graft function and survival after prolonged cold ischemia. Transplantation 2002 0.78
101 Imaging of mitochondrial pH using SNARF-1. Methods Mol Biol 2012 0.78
102 Rusty notions of cell injury. J Hepatol 2004 0.78
103 Minocycline and doxycycline, but not tetracycline, mitigate liver and kidney injury after hemorrhagic shock/resuscitation. Shock 2014 0.78
104 Ischemic preconditioning of rat livers from non-heart-beating donors decreases parenchymal cell killing and increases graft survival after transplantation. HPB Surg 2012 0.77
105 Minocycline decreases liver injury after hemorrhagic shock and resuscitation in mice. HPB Surg 2012 0.77
106 C-Jun N-Terminal Kinase 2 Promotes Liver Injury via the Mitochondrial Permeability Transition after Hemorrhage and Resuscitation. HPB Surg 2012 0.77
107 Small-for-Size Liver Transplantation Increases Pulmonary Injury in Rats: Prevention by NIM811. HPB Surg 2012 0.77
108 Polyphenols of Camellia sinenesis decrease mortality, hepatic injury and generation of cytokines and reactive oxygen and nitrogen species after hemorrhage/resuscitation in rats. BMC Complement Altern Med 2010 0.77
109 Icam-1 upregulation in ethanol-induced Fatty murine livers promotes injury and sinusoidal leukocyte adherence after transplantation. HPB Surg 2012 0.76
110 Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols. J Pharm Pharmacol 2006 0.76
111 Suramin decreases injury and improves regeneration of ethanol-induced steatotic partial liver grafts. J Pharmacol Exp Ther 2012 0.76
112 Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat. Liver Transpl 2006 0.76
113 Ischemia/Reperfusion injury in liver surgery and transplantation. HPB Surg 2012 0.76
114 Reply to "letter to the editor: 'cyclosporin A in left ventricular remodeling after myocardial infarction'". Am J Physiol Heart Circ Physiol 2014 0.75
115 Cyclosporine in acute myocardial infarction. N Engl J Med 2008 0.75
116 Genetic manipulation of sinusoidal endothelial cells. J Gastroenterol Hepatol 2007 0.75
117 Opioid receptor-independent protection of ischemic rat hepatocytes by morphine. Biochem Biophys Res Commun 2006 0.75
118 Whither our libraries? Gastroenterology 2004 0.75
119 ATP/ADP turnover and import of glycolytic ATP into mitochondria in cancer cells is independent of the adenine nucleotide translocator. J Biol Chem 2017 0.75