Published in Biochem J on April 01, 2009
A functional CFTR assay using primary cystic fibrosis intestinal organoids. Nat Med (2013) 1.87
Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers. J Physiol (2010) 1.27
Pharmacological rescue of the mutant cystic fibrosis transmembrane conductance regulator (CFTR) detected by use of a novel fluorescence platform. Mol Med (2012) 1.15
Bicarbonate-dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu-3. J Physiol (2012) 1.14
Comparative analysis of techniques to purify plasma membrane proteins. J Biomol Tech (2010) 1.05
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR). J Biol Chem (2013) 0.96
The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene. J Neurosci (2012) 0.87
The buffer capacity of airway epithelial secretions. Front Physiol (2014) 0.79
The cystic-fibrosis-associated ΔF508 mutation confers post-transcriptional destabilization on the C. elegans ABC transporter PGP-3. Dis Model Mech (2012) 0.78
Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein. J Neurosci (2015) 0.78
Mpl traffics to the cell surface through conventional and unconventional routes. Traffic (2014) 0.78
A small molecule mitigates hearing loss in a mouse model of Usher syndrome III. Nat Chem Biol (2016) 0.76
Investigating CFTR and KCa3.1 Protein/Protein Interactions. PLoS One (2016) 0.76
Endogenous surface expression of ΔF508-CFTR mediates cAMP-stimulated Cl(-) current in CFTR(ΔF508/ΔF508) pig thyroid epithelial cells. Exp Physiol (2011) 0.76
Insulin-like growth factor 1 (IGF-1) enhances the protein expression of CFTR. PLoS One (2013) 0.76
Life Stage-specific Proteomes of Legionella pneumophila Reveal a Highly Differential Abundance of Virulence-associated Dot/Icm effectors. Mol Cell Proteomics (2015) 0.75
Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol (2004) 6.35
Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers. Am J Respir Crit Care Med (2006) 2.34
Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR. Chem Biol (2011) 1.92
Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol (2007) 1.92
BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex. Cell (2008) 1.51
Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis. J Clin Invest (2007) 1.50
A haplotype-based molecular analysis of CFTR mutations associated with respiratory and pancreatic diseases. Hum Mol Genet (2003) 1.40
Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine. Mol Pharmacol (2010) 1.36
Membrane lateral diffusion and capture of CFTR within transient confinement zones. Biophys J (2006) 1.36
Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers. J Physiol (2010) 1.27
Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice. PLoS Genet (2009) 1.26
Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol Pharmacol (2007) 1.25
Correctors of protein trafficking defects identified by a novel high-throughput screening assay. Chembiochem (2007) 1.24
Mucus secretion by single tracheal submucosal glands from normal and cystic fibrosis transmembrane conductance regulator knockout mice. J Physiol (2007) 1.21
Oxidant stress suppresses CFTR expression. Am J Physiol Cell Physiol (2005) 1.19
Physiology of epithelial chloride and fluid secretion. Cold Spring Harb Perspect Med (2012) 1.16
Bicarbonate-dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu-3. J Physiol (2012) 1.14
Phosphorylation of CFTR by PKA promotes binding of the regulatory domain. EMBO J (2005) 1.14
ATP release from human airway epithelial cells studied using a capillary cell culture system. J Physiol (2002) 1.12
Role of the cystic fibrosis transmembrane conductance channel in human airway smooth muscle. Am J Respir Cell Mol Biol (2008) 1.10
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell (2012) 1.07
Is multidisciplinary care of heart failure cost-beneficial when combined with optimal medical care? Eur J Heart Fail (2003) 1.04
Investigating membrane protein dynamics in living cells. Biochem Cell Biol (2006) 1.04
The biologic variability of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide in stable heart failure patients. J Card Fail (2007) 1.02
The secret life of CFTR as a calcium-activated chloride channel. J Physiol (2013) 1.01
Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci U S A (2003) 1.00
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR). J Biol Chem (2013) 0.96
Clinical deterioration in established heart failure: what is the value of BNP and weight gain in aiding diagnosis? Eur J Heart Fail (2005) 0.96
Substance P stimulates CFTR-dependent fluid secretion by mouse tracheal submucosal glands. Pflugers Arch (2008) 0.96
Decompensation of chronic heart failure associated with pregabalin in patients with neuropathic pain. J Card Fail (2007) 0.94
Quality of life predicts outcome in a heart failure disease management program. Int J Cardiol (2008) 0.94
Basolateral chloride loading by the anion exchanger type 2: role in fluid secretion by the human airway epithelial cell line Calu-3. J Physiol (2012) 0.93
Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL-8 secretion by cystic fibrosis airways. FASEB J (2011) 0.92
Cystic fibrosis transmembrane conductance regulator is expressed in mucin granules from Calu-3 and primary human airway epithelial cells. Am J Respir Cell Mol Biol (2013) 0.87
Doppler-echocardiographic indices of diastolic function in heart failure admissions with preserved left ventricular systolic function. Eur J Heart Fail (2002) 0.87
Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP. Chem Biol (2012) 0.85
Decreasing Poly(ADP-Ribose) Polymerase Activity Restores ΔF508 CFTR Trafficking. Front Pharmacol (2012) 0.85
Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines. Orphanet J Rare Dis (2013) 0.85
Vasoactive intestinal peptide increases cystic fibrosis transmembrane conductance regulator levels in the apical membrane of Calu-3 cells through a protein kinase C-dependent mechanism. J Pharmacol Exp Ther (2008) 0.84
Ouabain Mimics Low Temperature Rescue of F508del-CFTR in Cystic Fibrosis Epithelial Cells. Front Pharmacol (2012) 0.83
Progression of preserved systolic function heart failure to systolic dysfunction -- a natural history study. Int J Cardiol (2006) 0.83
Measurement of fluid secretion from intact airway submucosal glands. Methods Mol Biol (2011) 0.81
PKC phosphorylation modulates PKA-dependent binding of the R domain to other domains of CFTR. Am J Physiol Cell Physiol (2008) 0.80
Modest elevation in BNP in asymptomatic hypertensive patients reflects sub-clinical cardiac remodeling, inflammation and extracellular matrix changes. PLoS One (2012) 0.79
Very late bare-metal stent thrombosis, rare but stormy! J Invasive Cardiol (2011) 0.78
CFTR regulation by phosphorylation. Methods Mol Med (2002) 0.78
Imaging and organelle distribution of fluorescent InGaP/ZnS nanoparticles in glial cells. Nanomedicine (Lond) (2009) 0.77
Integration of B-type natriuretic Peptide in heart failure outpatient programs. Congest Heart Fail (2008) 0.77
Specialist nurse supervised in-hospital titration to target dose ACE inhibitor--is it safe and feasible in a community heart failure population? Eur J Cardiovasc Nurs (2003) 0.77
Polymer assisted entrapment of netilmicin in PLGA nanoparticles for sustained antibacterial activity. J Microencapsul (2014) 0.76
Heart failure care in a hospital unit: a comparison of standard 3-month and extended 6-month programs. Eur J Heart Fail (2005) 0.76
Prevalence of heart failure: a reflection of the good and the bad of modern cardiovascular care. Rev Esp Cardiol (2008) 0.75
Disease management programs for heart failure: not just for the 'sick' heart failure population. Eur J Heart Fail (2006) 0.75
Multidisciplinary care of heart failure: what have we learned and where can we improve? Eur J Cardiovasc Nurs (2003) 0.75