Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect.

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Published in Mol Pharmacol on November 01, 2007

Authors

Renaud Robert1, Graeme W Carlile, Catalin Pavel, Na Liu, Suzana M Anjos, Jie Liao, Yishan Luo, Donglei Zhang, David Y Thomas, John W Hanrahan

Author Affiliations

1: McIntyre Building, Physiology Department, 3655 Promenade Sir William Osler, Montreal, Quebec, H3G 1Y6, Canada. renaud.robert@mcgill.ca

Associated clinical trials:

Effects of Sildenafil on CFTR-dependent Ion Transport Activity | NCT01132482

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