Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena.

PubWeight™: 3.16‹?› | Rank: Top 1%

🔗 View Article (PMID 12297044)

Published in Cell on September 20, 2002

Authors

Sean D Taverna1, Robert S Coyne, C David Allis

Author Affiliations

1: Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, VA 22908, USA.

Articles citing this

(truncated to the top 100)

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev (2005) 12.15

Small RNAs as guardians of the genome. Cell (2009) 8.88

RNAi-mediated targeting of heterochromatin by the RITS complex. Science (2004) 8.73

Small RNAs in transcriptional gene silencing and genome defence. Nature (2009) 5.98

Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell (2006) 3.87

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond. Nat Rev Genet (2013) 3.17

A novel repeat-associated small interfering RNA-mediated silencing pathway downregulates complementary sense gypsy transcripts in somatic cells of the Drosophila ovary. J Virol (2006) 2.87

A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase. Genes Dev (2004) 2.75

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation. Mol Cell Biol (2007) 2.69

Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43

RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev (2007) 2.26

Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. Mol Cell Biol (2003) 2.22

RNA interference: biology, mechanism, and applications. Microbiol Mol Biol Rev (2003) 2.19

Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena. Proc Natl Acad Sci U S A (2004) 2.10

Two classes of endogenous small RNAs in Tetrahymena thermophila. Genes Dev (2005) 2.08

Germ line transcripts are processed by a Dicer-like protein that is essential for developmentally programmed genome rearrangements of Tetrahymena thermophila. Mol Cell Biol (2005) 2.06

Study of an RNA helicase implicates small RNA-noncoding RNA interactions in programmed DNA elimination in Tetrahymena. Genes Dev (2008) 1.82

Genes and transposons are differentially methylated in plants, but not in mammals. Genome Res (2003) 1.66

Maternal noncoding transcripts antagonize the targeting of DNA elimination by scanRNAs in Paramecium tetraurelia. Genes Dev (2008) 1.60

RNA-mediated programming of developmental genome rearrangements in Paramecium tetraurelia. Mol Cell Biol (2004) 1.57

Effects of length and location on the cellular response to double-stranded RNA. Microbiol Mol Biol Rev (2004) 1.57

PIWI proteins and PIWI-interacting RNAs in the soma. Nature (2014) 1.53

A domesticated piggyBac transposase plays key roles in heterochromatin dynamics and DNA cleavage during programmed DNA deletion in Tetrahymena thermophila. Mol Biol Cell (2010) 1.42

Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure. BMC Genomics (2008) 1.40

Pdsg1 and Pdsg2, novel proteins involved in developmental genome remodelling in Paramecium. PLoS One (2014) 1.40

RNAi-dependent and RNAi-independent mechanisms contribute to the silencing of RIPed sequences in Neurospora crassa. Nucleic Acids Res (2004) 1.38

Dogma derailed: the many influences of RNA on the genome. Mol Cell (2013) 1.36

Silencing-associated and meiosis-specific small RNA pathways in Paramecium tetraurelia. Nucleic Acids Res (2008) 1.34

Developmentally regulated chromosome fragmentation linked to imprecise elimination of repeated sequences in paramecia. Eukaryot Cell (2003) 1.30

Uniparental chromosome elimination at mitosis and interphase in wheat and pearl millet crosses involves micronucleus formation, progressive heterochromatinization, and DNA fragmentation. Plant Cell (2005) 1.26

The Tetrahymena argonaute-binding protein Giw1p directs a mature argonaute-siRNA complex to the nucleus. Cell (2010) 1.25

Dynamic nuclear reorganization during genome remodeling of Tetrahymena. Biochim Biophys Acta (2008) 1.25

Communication between parental and developing genomes during tetrahymena nuclear differentiation is likely mediated by homologous RNAs. Genetics (2004) 1.21

Transcriptome analysis of the model protozoan, Tetrahymena thermophila, using Deep RNA sequencing. PLoS One (2012) 1.19

Induction of gene silencing by hairpin RNA expression in Tetrahymena thermophila reveals a second small RNA pathway. Mol Cell Biol (2006) 1.15

Epigenetics of ciliates. Cold Spring Harb Perspect Biol (2013) 1.14

A non-long terminal repeat retrotransposon family is restricted to the germ line micronucleus of the ciliated protozoan Tetrahymena thermophila. Eukaryot Cell (2004) 1.12

Biased transcription and selective degradation of small RNAs shape the pattern of DNA elimination in Tetrahymena. Genes Dev (2012) 1.10

Stress-induced cell reprogramming. A role for global genome regulation? Plant Physiol (2004) 1.09

RNA-Mediated Epigenetic Programming of Genome Rearrangements. Annu Rev Genomics Hum Genet (2011) 1.06

RNA turnover and chromatin-dependent gene silencing. Chromosoma (2008) 1.05

Elimination of foreign DNA during somatic differentiation in Tetrahymena thermophila shows position effect and is dosage dependent. Eukaryot Cell (2005) 1.04

Epigenetic virtues of chromodomains. Crit Rev Biochem Mol Biol (2011) 1.03

Mating of the stichotrichous ciliate Oxytricha trifallax induces production of a class of 27 nt small RNAs derived from the parental macronucleus. PLoS One (2012) 1.03

Spatial and temporal plasticity of chromatin during programmed DNA-reorganization in Stylonychia macronuclear development. Epigenetics Chromatin (2008) 1.00

Lia1p, a novel protein required during nuclear differentiation for genome-wide DNA rearrangements in Tetrahymena thermophila. Eukaryot Cell (2007) 0.99

Developmentally programmed DNA splicing in Paramecium reveals short-distance crosstalk between DNA cleavage sites. Nucleic Acids Res (2008) 0.99

Centromeric histone H3 is essential for vegetative cell division and for DNA elimination during conjugation in Tetrahymena thermophila. Mol Cell Biol (2006) 0.98

Programmed DNA elimination in Tetrahymena: a small RNA-mediated genome surveillance mechanism. Adv Exp Med Biol (2011) 0.97

An essential role for the DNA breakage-repair protein Ku80 in programmed DNA rearrangements in Tetrahymena thermophila. Mol Biol Cell (2012) 0.97

Two GW repeat proteins interact with Tetrahymena thermophila argonaute and promote genome rearrangement. Mol Cell Biol (2009) 0.97

A domesticated PiggyBac transposase interacts with heterochromatin and catalyzes reproducible DNA elimination in Tetrahymena. PLoS Genet (2013) 0.94

The conjugation-specific Die5 protein is required for development of the somatic nucleus in both Paramecium and Tetrahymena. Eukaryot Cell (2010) 0.94

Epigenetic inheritance in ciliates. Curr Opin Microbiol (2009) 0.94

Genomes on the edge: programmed genome instability in ciliates. Cell (2013) 0.93

The germ line limited M element of Tetrahymena is targeted for elimination from the somatic genome by a homology-dependent mechanism. Nucleic Acids Res (2006) 0.93

The fascinating world of RNA interference. Int J Biol Sci (2009) 0.92

A Tetrahymena Hsp90 co-chaperone promotes siRNA loading by ATP-dependent and ATP-independent mechanisms. EMBO J (2015) 0.89

Gigantic macroautophagy in programmed nuclear death of Tetrahymena thermophila. Autophagy (2010) 0.89

Tetrahymena thermophila JMJD3 homolog regulates H3K27 methylation and nuclear differentiation. Eukaryot Cell (2012) 0.89

The SUMO pathway is developmentally regulated and required for programmed DNA elimination in Paramecium tetraurelia. Eukaryot Cell (2006) 0.88

Keeping the soma free of transposons: programmed DNA elimination in ciliates. J Biol Chem (2011) 0.88

Small-RNA-Mediated Genome-wide trans-Recognition Network in Tetrahymena DNA Elimination. Mol Cell (2015) 0.88

DNA rearrangements directed by non-coding RNAs in ciliates. Wiley Interdiscip Rev RNA (2011) 0.88

Transposon domestication versus mutualism in ciliate genome rearrangements. PLoS Genet (2013) 0.87

LIA5 is required for nuclear reorganization and programmed DNA rearrangements occurring during tetrahymena macronuclear differentiation. PLoS One (2013) 0.87

Zygotic expression of the double-stranded RNA binding motif protein Drb2p is required for DNA elimination in the ciliate Tetrahymena thermophila. Eukaryot Cell (2011) 0.87

Asymmetric epigenetic modification and elimination of rDNA sequences by polyploidization in wheat. Plant Cell (2014) 0.87

Polymorphism, recombination and alternative unscrambling in the DNA polymerase alpha gene of the ciliate Stylonychia lemnae (Alveolata; class Spirotrichea). Genetics (2003) 0.87

Developmentally programmed, RNA-directed genome rearrangement in Tetrahymena. Dev Growth Differ (2011) 0.85

Programmed Genome Rearrangements in the Ciliate Oxytricha. Microbiol Spectr (2014) 0.84

Diverse sequences within Tlr elements target programmed DNA elimination in Tetrahymena thermophila. Eukaryot Cell (2003) 0.84

Exploring microRNA-like small RNAs in the filamentous fungus Fusarium oxysporum. PLoS One (2014) 0.83

Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis. Elife (2014) 0.83

Phosphorylation of an HP1-like Protein Regulates Heterochromatin Body Assembly for DNA Elimination. Dev Cell (2015) 0.83

Class I histone deacetylase Thd1p promotes global chromatin condensation in Tetrahymena thermophila. Eukaryot Cell (2007) 0.83

Local effect of enhancer of zeste-like reveals cooperation of epigenetic and cis-acting determinants for zygotic genome rearrangements. PLoS Genet (2014) 0.83

Dimethylated H3K27 Is a Repressive Epigenetic Histone Mark in the Protist Entamoeba histolytica and Is Significantly Enriched in Genes Silenced via the RNAi Pathway. J Biol Chem (2015) 0.81

RNAi hushes heterochromatin. Genome Biol (2002) 0.80

LIA4 encodes a chromoshadow domain protein required for genomewide DNA rearrangements in Tetrahymena thermophila. Eukaryot Cell (2014) 0.79

Nuclear Noncoding RNAs and Genome Stability. Mol Cell (2016) 0.79

Mutations in Pdd1 reveal distinct requirements for its chromodomain and chromoshadow domain in directing histone methylation and heterochromatin elimination. Eukaryot Cell (2013) 0.79

Subtraction by addition: domesticated transposases in programmed DNA elimination. Genes Dev (2009) 0.78

Role of micronucleus-limited DNA in programmed deletion of mse2.9 during macronuclear development of Tetrahymena thermophila. Eukaryot Cell (2004) 0.78

Tetrahymena as a Unicellular Model Eukaryote: Genetic and Genomic Tools. Genetics (2016) 0.78

Targeted Gene Disruption by Ectopic Induction of DNA Elimination in Tetrahymena. Genetics (2015) 0.78

Whole chromosome elimination and chromosome terminus elimination both contribute to somatic differentiation in Taiwanese hagfish Paramyxine sheni. Chromosome Res (2010) 0.78

Tetrahymena Pot2 is a developmentally regulated paralog of Pot1 that localizes to chromosome breakage sites but not to telomeres. Eukaryot Cell (2014) 0.77

A Parallel G Quadruplex-Binding Protein Regulates the Boundaries of DNA Elimination Events of Tetrahymena thermophila. PLoS Genet (2016) 0.77

Role of class III phosphatidylinositol 3-kinase during programmed nuclear death of Tetrahymena thermophila. Autophagy (2013) 0.77

Phosphorylation of an HP1-like protein is a prerequisite for heterochromatin body formation in Tetrahymena DNA elimination. Proc Natl Acad Sci U S A (2016) 0.77

Molecular genetic analysis of an SNF2/brahma-related gene in Tetrahymena thermophila suggests roles in growth and nuclear development. Eukaryot Cell (2006) 0.77

Chromodomain protein Tcd1 is required for macronuclear genome rearrangement and repair in Tetrahymena. Sci Rep (2015) 0.77

Programmed Minichromosome Elimination as a Mechanism for Somatic Genome Reduction in Tetrahymena thermophila. PLoS Genet (2016) 0.76

Beyond transcriptional silencing: is methylcytosine a widely conserved eukaryotic DNA elimination mechanism? Bioessays (2014) 0.76

DRH1, a p68-related RNA helicase, is required for chromosome breakage in Tetrahymena. Biol Open (2016) 0.75

Non-Mendelian inheritance induced by gene amplification in the germ nucleus of Paramecium tetraurelia. Genetics (2004) 0.75

Dissecting relative contributions of cis- and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin. Nucleic Acids Res (2016) 0.75

Intercepting noncoding messages between germline and soma. Genes Dev (2012) 0.75

Phosphorylation-Dependent Targeting of Tetrahymena HP1 to Condensed Chromatin. mSphere (2016) 0.75

Articles by these authors

(truncated to the top 100)

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature (2007) 11.14

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature (2006) 10.73

Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol Cell (2007) 9.73

Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature (2007) 9.25

WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell (2005) 8.86

Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (2010) 8.79

Histone and chromatin cross-talk. Curr Opin Cell Biol (2003) 8.69

Epigenetics: a landscape takes shape. Cell (2007) 8.29

MLL targets SET domain methyltransferase activity to Hox gene promoters. Mol Cell (2002) 8.17

Multivalent engagement of chromatin modifications by linked binding modules. Nat Rev Mol Cell Biol (2007) 8.14

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev (2003) 7.91

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature (2006) 7.70

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature (2002) 7.54

Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell (2003) 6.44

Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40

Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (2013) 6.29

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer (2010) 6.27

Extraction, purification and analysis of histones. Nat Protoc (2007) 6.25

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell (2005) 6.12

Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol (2006) 6.03

Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. Mol Cell Biol (2006) 5.99

Epigenetic dynamics of imprinted X inactivation during early mouse development. Science (2003) 5.80

RNA meets chromatin. Genes Dev (2005) 5.66

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. Mol Cell (2002) 5.59

Human PAD4 regulates histone arginine methylation levels via demethylimination. Science (2004) 5.46

Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. PLoS Biol (2006) 5.44

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev (2002) 5.43

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol (2002) 5.42

New nomenclature for chromatin-modifying enzymes. Cell (2007) 5.34

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol (2009) 5.27

Binary switches and modification cassettes in histone biology and beyond. Nature (2003) 4.75

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. Proc Natl Acad Sci U S A (2010) 4.73

Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa. Nat Genet (2003) 4.56

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol Cell Biol (2002) 4.50

Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell (2003) 4.13

Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell (2006) 3.87

Organismal differences in post-translational modifications in histones H3 and H4. J Biol Chem (2006) 3.84

Gene silencing: trans-histone regulatory pathway in chromatin. Nature (2002) 3.77

Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes. Nat Genet (2001) 3.63

Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes. Genes Dev (2002) 3.37

Decoding the epigenetic language of neuronal plasticity. Neuron (2008) 3.23

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature (2009) 3.13

Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09

Expression patterns and post-translational modifications associated with mammalian histone H3 variants. J Biol Chem (2005) 3.00

Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia. PLoS Genet (2012) 2.94

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity. Nature (2008) 2.86

Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation. Genes Dev (2007) 2.81

Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell (2011) 2.68

Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis". Proc Natl Acad Sci U S A (2006) 2.68

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours. Nature (2010) 2.65

Chromatin remodeling and cancer, Part I: Covalent histone modifications. Trends Mol Med (2007) 2.60

Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription. J Biol Chem (2003) 2.48

Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger. Mol Cell (2007) 2.47

Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell (2010) 2.44

Evidence that Set1, a factor required for methylation of histone H3, regulates rDNA silencing in S. cerevisiae by a Sir2-independent mechanism. Curr Biol (2002) 2.44

Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43

Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome. Mol Cell Biol (2004) 2.43

KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors. Cell (2013) 2.34

PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks. Mutat Res (2008) 2.31

Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat Struct Mol Biol (2006) 2.29

RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev (2007) 2.26

Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis. Mol Cell (2010) 2.25

The nucleation and maintenance of heterochromatin by a histone deacetylase in fission yeast. Mol Cell (2005) 2.19

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nat Struct Mol Biol (2011) 2.18

Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc Natl Acad Sci U S A (2003) 2.16

Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae. Cell (2005) 2.15

Histone arginine methylation and its dynamic regulation. Front Biosci (2006) 2.06

Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Mol Cell Biol (2008) 2.05

Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. Genes Dev (2006) 2.05

Operating on chromatin, a colorful language where context matters. J Mol Biol (2011) 2.00

New functions for an old variant: no substitute for histone H3.3. Curr Opin Genet Dev (2010) 1.93

Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A (2005) 1.91

Proteome-wide prediction of acetylation substrates. Proc Natl Acad Sci U S A (2009) 1.81

Polycomb Group proteins: an evolutionary perspective. Trends Genet (2007) 1.79

Cancer. New epigenetic drivers of cancers. Science (2011) 1.73

Histone H2B deacetylation at lysine 11 is required for yeast apoptosis induced by phosphorylation of H2B at serine 10. Mol Cell (2006) 1.72

Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons. J Cell Sci (2003) 1.70

Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration. Proc Natl Acad Sci U S A (2010) 1.68

DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition. Nature (2012) 1.65

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes. Proc Natl Acad Sci U S A (2011) 1.65

Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. Mol Cell Biol (2002) 1.63

Chromatin remodeling and cancer, Part II: ATP-dependent chromatin remodeling. Trends Mol Med (2007) 1.59

Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity. Genes Dev (2008) 1.51

Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. J Biol Chem (2006) 1.50

Phosphorylation of histone H2B at DNA double-strand breaks. J Exp Med (2004) 1.49

The enhancement of histone H4 and H2A serine 1 phosphorylation during mitosis and S-phase is evolutionarily conserved. Chromosoma (2004) 1.47

Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis. Proc Natl Acad Sci U S A (2002) 1.46

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Mol Cell (2012) 1.43

Histone variants in metazoan development. Dev Cell (2010) 1.42

Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae. Curr Biol (2005) 1.41

Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent. J Biol Chem (2009) 1.38

Taking LSD 1 to a new high. Cell (2005) 1.34

Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Cancer Discov (2012) 1.33

Histone regulation in the CNS: basic principles of epigenetic plasticity. Neuropsychopharmacology (2012) 1.33

Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry. J Proteome Res (2004) 1.33

Dynamic alterations of specific histone modifications during early murine development. J Cell Sci (2004) 1.30

Modifications of human histone H3 variants during mitosis. Biochemistry (2005) 1.29

Identification of novel chromatin-associated proteins involved in programmed genome rearrangements in Tetrahymena. J Cell Sci (2007) 1.28

Analysis of histones in Xenopus laevis. I. A distinct index of enriched variants and modifications exists in each cell type and is remodeled during developmental transitions. J Biol Chem (2008) 1.26

Comprehensive phosphoprotein analysis of linker histone H1 from Tetrahymena thermophila. Mol Cell Proteomics (2006) 1.26