A phosphomimetic mutation at threonine-57 abolishes transactivation activity and alters nuclear localization pattern of human pregnane x receptor.

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Published in Drug Metab Dispos on January 26, 2009

Authors

Satyanarayana R Pondugula1, Cynthia Brimer-Cline, Jing Wu, Erin G Schuetz, Rakesh K Tyagi, Taosheng Chen

Author Affiliations

1: Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 1000, Memphis, TN 38105, USA.

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