Published in Nucleic Acids Res on July 01, 2005
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics (2008) 4.33
KinasePhos 2.0: a web server for identifying protein kinase-specific phosphorylation sites based on sequences and coupling patterns. Nucleic Acids Res (2007) 2.69
NetworKIN: a resource for exploring cellular phosphorylation networks. Nucleic Acids Res (2007) 2.69
PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory. BMC Bioinformatics (2006) 2.34
SUMOsp: a web server for sumoylation site prediction. Nucleic Acids Res (2006) 1.88
Phosphoproteomics for the masses. ACS Chem Biol (2010) 1.83
Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid. Protein Sci (2008) 1.54
pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model. Biol Direct (2007) 1.46
MMFPh: a maximal motif finder for phosphoproteomics datasets. Bioinformatics (2012) 1.44
GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithm. PLoS One (2010) 1.40
Prediction of kinase-specific phosphorylation sites using conditional random fields. Bioinformatics (2008) 1.38
Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2. J Cell Biol (2007) 1.31
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway. Cancer Res (2012) 1.30
Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules. Semin Cell Dev Biol (2010) 1.25
Prediction of Nepsilon-acetylation on internal lysines implemented in Bayesian Discriminant Method. Biochem Biophys Res Commun (2006) 1.24
Meta-prediction of phosphorylation sites with weighted voting and restricted grid search parameter selection. Nucleic Acids Res (2008) 1.20
GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. J Immunol (2013) 1.19
A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway. Genes Dev (2010) 1.16
Role of the PI3-kinase/mTor pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression by insulin in liver. J Cell Commun Signal (2007) 1.13
NBA-Palm: prediction of palmitoylation site implemented in Naïve Bayes algorithm. BMC Bioinformatics (2006) 1.12
Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1. EMBO J (2010) 1.12
PlantPhos: using maximal dependence decomposition to identify plant phosphorylation sites with substrate site specificity. BMC Bioinformatics (2011) 1.10
MeMo: a web tool for prediction of protein methylation modifications. Nucleic Acids Res (2006) 1.09
Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites. BMC Bioinformatics (2008) 1.07
A phosphomimetic mutation at threonine-57 abolishes transactivation activity and alters nuclear localization pattern of human pregnane x receptor. Drug Metab Dispos (2009) 1.07
GPS-CCD: a novel computational program for the prediction of calpain cleavage sites. PLoS One (2011) 1.04
RegPhos: a system to explore the protein kinase-substrate phosphorylation network in humans. Nucleic Acids Res (2010) 1.03
AtSIG6, a plastid sigma factor from Arabidopsis, reveals functional impact of cpCK2 phosphorylation. Plant J (2010) 1.00
Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production. J Biol Chem (2010) 0.99
MODPROPEP: a program for knowledge-based modeling of protein-peptide complexes. Nucleic Acids Res (2007) 0.96
Negative regulation of the yeast ABC transporter Ycf1p by phosphorylation within its N-terminal extension. J Biol Chem (2008) 0.95
Identifying protein phosphorylation sites with kinase substrate specificity on human viruses. PLoS One (2012) 0.93
AMS 4.0: consensus prediction of post-translational modifications in protein sequences. Amino Acids (2012) 0.88
The Predikin webserver: improved prediction of protein kinase peptide specificity using structural information. Nucleic Acids Res (2008) 0.88
Protein kinase target discovery from genome-wide messenger RNA expression profiling. Mt Sinai J Med (2010) 0.87
Prediction of phosphothreonine sites in human proteins by fusing different features. Sci Rep (2016) 0.86
AMS 3.0: prediction of post-translational modifications. BMC Bioinformatics (2010) 0.86
Mariner Mos1 transposase optimization by rational mutagenesis. Genetica (2009) 0.85
SiteSeek: post-translational modification analysis using adaptive locality-effective kernel methods and new profiles. BMC Bioinformatics (2008) 0.84
A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic data. Mol Cell Proteomics (2010) 0.83
ERK-mediated activation of Fas apoptotic inhibitory molecule 2 (Faim2) prevents apoptosis of 661W cells in a model of detachment-induced photoreceptor cell death. PLoS One (2012) 0.82
Toward a systems-level view of dynamic phosphorylation networks. Front Genet (2014) 0.82
Yeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment. Mol Cell Biol (2012) 0.82
Non-catalytic participation of the Pin1 peptidyl-prolyl isomerase domain in target binding. Front Physiol (2013) 0.81
Rice_Phospho 1.0: a new rice-specific SVM predictor for protein phosphorylation sites. Sci Rep (2015) 0.81
Mutations in two putative phosphorylation motifs in the tomato pollen receptor kinase LePRK2 show antagonistic effects on pollen tube length. J Biol Chem (2010) 0.80
Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteins. DNA Repair (Amst) (2015) 0.80
An ensemble method approach to investigate kinase-specific phosphorylation sites. Int J Nanomedicine (2014) 0.79
A grammar inference approach for predicting kinase specific phosphorylation sites. PLoS One (2015) 0.78
An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. Elife (2016) 0.78
PhosphoRice: a meta-predictor of rice-specific phosphorylation sites. Plant Methods (2012) 0.78
cAMP protein kinase phosphorylates the Mos1 transposase and regulates its activity: evidences from mass spectrometry and biochemical analyses. Nucleic Acids Res (2013) 0.77
Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. J Clin Invest (2017) 0.77
SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Ser62. Oncogene (2015) 0.76
Molecular Screen Identifies Cardiac Myosin-Binding Protein-C as a Protein Kinase G-Iα Substrate. Circ Heart Fail (2015) 0.76
Roles of Us8A and Its Phosphorylation Mediated by Us3 in Herpes Simplex Virus 1 Pathogenesis. J Virol (2016) 0.76
The Strica Homolog AaCASPS16 Is Involved in Apoptosis in the Yellow Fever Vector, Aedes albopictus. PLoS One (2016) 0.75
K-CLASP: A tool to identify phosphosite specific kinases and interacting proteins. ACS Chem Biol (2016) 0.75
Transcriptional profiling of PRKG2-null growth plate identifies putative down-stream targets of PRKG2. BMC Res Notes (2015) 0.75
Catalytic activity of cGMP-dependent protein kinase type I in intact cells is independent of N-terminal autophosphorylation. PLoS One (2014) 0.75
DephosSite: a machine learning approach for discovering phosphotase-specific dephosphorylation sites. Sci Rep (2016) 0.75
Kif4 Is Essential for Mouse Oocyte Meiosis. PLoS One (2017) 0.75
Comparative proteomic study of Arabidopsis mutants mpk4 and mpk6. Sci Rep (2016) 0.75
Regulation of divalent metal transporter-1 by serine phosphorylation. Biochem J (2016) 0.75
Phosphorylation of MAP65-1 by Arabidopsis Aurora kinases is required for efficient cell cycle progression. Plant Physiol (2016) 0.75
PhosphoPredict: A bioinformatics tool for prediction of human kinase-specific phosphorylation substrates and sites by integrating heterogeneous feature selection. Sci Rep (2017) 0.75
The protein kinase complement of the human genome. Science (2002) 35.36
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res (2003) 15.74
Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J Mol Biol (1999) 15.63
Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc Natl Acad Sci U S A (2004) 10.78
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol (2002) 8.37
The importance of intrinsic disorder for protein phosphorylation. Nucleic Acids Res (2004) 8.23
Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics (2004) 7.76
Phospho.ELM: a database of experimentally verified phosphorylation sites in eukaryotic proteins. BMC Bioinformatics (2004) 4.44
Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines. Proc Natl Acad Sci U S A (1997) 2.77
PhosphoBase, a database of phosphorylation sites: release 2.0. Nucleic Acids Res (1999) 2.61
The mouse kinome: discovery and comparative genomics of all mouse protein kinases. Proc Natl Acad Sci U S A (2004) 2.50
Phosphoproteomic analysis of the developing mouse brain. Mol Cell Proteomics (2004) 2.50
Spinophilin regulates the formation and function of dendritic spines. Proc Natl Acad Sci U S A (2000) 2.32
GPS: a novel group-based phosphorylation predicting and scoring method. Biochem Biophys Res Commun (2004) 2.17
Structural basis and prediction of substrate specificity in protein serine/threonine kinases. Proc Natl Acad Sci U S A (2002) 2.07
Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites. J Biol Chem (1998) 1.82
Amino acids determining enzyme-substrate specificity in prokaryotic and eukaryotic protein kinases. Proc Natl Acad Sci U S A (2003) 1.67
Statistical analysis of protein kinase specificity determinants. FEBS Lett (1998) 1.53
Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1. Biochemistry (1999) 1.48
Phosphorylation of spinophilin modulates its interaction with actin filaments. J Biol Chem (2002) 1.23
Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin. J Neurochem (2004) 1.06
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5). Proc Natl Acad Sci U S A (2005) 1.05
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics (2008) 4.33
CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. Cancer Cell (2011) 3.31
CSS-Palm 2.0: an updated software for palmitoylation sites prediction. Protein Eng Des Sel (2008) 2.86
DOG 1.0: illustrator of protein domain structures. Cell Res (2009) 2.77
Bulk metallic glass composites with transformation-mediated work-hardening and ductility. Adv Mater (2010) 2.71
PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory. BMC Bioinformatics (2006) 2.34
GPS: a novel group-based phosphorylation predicting and scoring method. Biochem Biophys Res Commun (2004) 2.17
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death. Cell Res (2009) 2.07
Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis. J Biol Chem (2003) 2.06
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation. Mol Cell (2012) 2.02
SUMOsp: a web server for sumoylation site prediction. Nucleic Acids Res (2006) 1.88
Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP. Genes Dev (2011) 1.87
A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer. Clin Cancer Res (2007) 1.77
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis. Cell Res (2007) 1.71
Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun (2004) 1.63
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling. J Biol Chem (2004) 1.58
Insights into plant biomass conversion from the genome of the anaerobic thermophilic bacterium Caldicellulosiruptor bescii DSM 6725. Nucleic Acids Res (2011) 1.48
Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. J Biol Chem (2004) 1.44
Aurora B kinase activation requires survivin priming phosphorylation by PLK1. J Mol Cell Biol (2010) 1.43
Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR. J Cell Biol (2006) 1.43
CSS-Palm: palmitoylation site prediction with a clustering and scoring strategy (CSS). Bioinformatics (2006) 1.42
GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithm. PLoS One (2010) 1.40
Real time remote monitoring and pre-warning system for Highway landslide in mountain area. J Environ Sci (China) (2011) 1.38
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3. Oncogene (2005) 1.33
Genome sequence of the anaerobic, thermophilic, and cellulolytic bacterium "Anaerocellum thermophilum" DSM 6725. J Bacteriol (2009) 1.33
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
MUST: a system for identification of miniature inverted-repeat transposable elements and applications to Anabaena variabilis and Haloquadratum walsbyi. Gene (2009) 1.30
Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase. Mol Biol Cell (2007) 1.30
Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem (2007) 1.27
Prediction of Nepsilon-acetylation on internal lysines implemented in Bayesian Discriminant Method. Biochem Biophys Res Commun (2006) 1.24
PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity. J Biol Chem (2010) 1.24
Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization. J Biol Chem (2008) 1.21
TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep (2009) 1.19
Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation. J Biol Chem (2003) 1.19
A genome-wide analysis of sumoylation-related biological processes and functions in human nucleus. FEBS Lett (2005) 1.15
PhosSNP for systematic analysis of genetic polymorphisms that influence protein phosphorylation. Mol Cell Proteomics (2009) 1.15
PALS1 specifies the localization of ezrin to the apical membrane of gastric parietal cells. J Biol Chem (2005) 1.15
PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. Biochem Biophys Res Commun (2006) 1.14
NBA-Palm: prediction of palmitoylation site implemented in Naïve Bayes algorithm. BMC Bioinformatics (2006) 1.12
Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres. EMBO Rep (2012) 1.12
CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosis. J Biol Chem (2011) 1.12
Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell. J Cell Sci (2005) 1.12
Rho kinase phosphorylation promotes ezrin-mediated metastasis in hepatocellular carcinoma. Cancer Res (2011) 1.11
PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation. J Biol Chem (2009) 1.09
EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis. Proc Natl Acad Sci U S A (2012) 1.09
MeMo: a web tool for prediction of protein methylation modifications. Nucleic Acids Res (2006) 1.09
Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin. Endocrinology (2006) 1.08
CPLA 1.0: an integrated database of protein lysine acetylation. Nucleic Acids Res (2010) 1.08
Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity. Clin Cancer Res (2004) 1.08
PRC1 cooperates with CLASP1 to organize central spindle plasticity in mitosis. J Biol Chem (2009) 1.06
CENP-U cooperates with Hec1 to orchestrate kinetochore-microtubule attachment. J Biol Chem (2010) 1.06
Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules. J Biol Chem (2012) 1.05
Emperipolesis, entosis and beyond: dance with fate. Cell Res (2008) 1.05
A summary of computational resources for protein phosphorylation. Curr Protein Pept Sci (2010) 1.05
Prediction of pathogenicity islands in enterohemorrhagic Escherichia coli O157:H7 using genomic barcodes. FEBS Lett (2010) 1.05
Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4. Mol Cell Proteomics (2006) 1.05
A recently active miniature inverted-repeat transposable element, Chunjie, inserted into an operon without disturbing the operon structure in Geobacter uraniireducens Rf4. Genetics (2008) 1.05
De novo computational prediction of non-coding RNA genes in prokaryotic genomes. Bioinformatics (2009) 1.04
Helicobacter pylori VacA disrupts apical membrane-cytoskeletal interactions in gastric parietal cells. J Biol Chem (2008) 1.04
Polarized distribution of IQGAP proteins in gastric parietal cells and their roles in regulated epithelial cell secretion. Mol Biol Cell (2003) 1.03
The structure of the FANCM-MHF complex reveals physical features for functional assembly. Nat Commun (2012) 1.03
Syntaxin 3 is required for cAMP-induced acid secretion: streptolysin O-permeabilized gastric gland model. Am J Physiol Gastrointest Liver Physiol (2002) 1.03
A general user interface for prediction servers of proteins' post-translational modification sites. Nat Protoc (2006) 1.00
Differential secretome analysis reveals CST6 as a suppressor of breast cancer bone metastasis. Cell Res (2012) 1.00
Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore. J Biol Chem (2013) 0.99
Diffusion-weighted MRI: a useful technique to discriminate benign versus malignant ovarian surface epithelial tumors with solid and cystic components. Abdom Imaging (2012) 0.99
Phospho-regulation of HsCdc14A By Polo-like kinase 1 is essential for mitotic progression. J Biol Chem (2007) 0.98
SUV39H1 orchestrates temporal dynamics of centromeric methylation essential for faithful chromosome segregation in mitosis. J Mol Cell Biol (2012) 0.98
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin. Cell Res (2010) 0.98
Mitotic regulator Mis18β interacts with and specifies the centromeric assembly of molecular chaperone holliday junction recognition protein (HJURP). J Biol Chem (2014) 0.97
SUMO-1 modification increases human SOD1 stability and aggregation. Biochem Biophys Res Commun (2006) 0.96
Phospho-regulated ACAP4-Ezrin interaction is essential for histamine-stimulated parietal cell secretion. J Biol Chem (2010) 0.93
Interaction of Skp1 with CENP-E at the midbody is essential for cytokinesis. Biochem Biophys Res Commun (2006) 0.93
A new approach for analyzing average time complexity of population-based evolutionary algorithms on unimodal problems. IEEE Trans Syst Man Cybern B Cybern (2009) 0.92
MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochore. Nucleic Acids Res (2009) 0.92
Computational analyses of TBC protein family in eukaryotes. Protein Pept Lett (2008) 0.91
TTK kinase is essential for the centrosomal localization of TACC2. FEBS Lett (2004) 0.91
Bis[hexa-amminecobalt(III)] penta-chloride nitrate. Acta Crystallogr Sect E Struct Rep Online (2012) 0.91
Single-molecule detection of phosphorylation-induced plasticity changes during ezrin activation. FEBS Lett (2007) 0.90
Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells. Gastroenterology (2002) 0.89
Mitotic phosphorylation of PRC1 at Thr470 is required for PRC1 oligomerization and proper central spindle organization. Cell Res (2007) 0.89
Deletion of the late cornified envelope genes LCE3C and LCE3B is associated with psoriasis in a Chinese population. J Invest Dermatol (2011) 0.89
Dimerization of CPAP orchestrates centrosome cohesion plasticity. J Biol Chem (2009) 0.89
Localization and function of soluble N-ethylmaleimide-sensitive factor attachment protein-25 and vesicle-associated membrane protein-2 in functioning gastric parietal cells. J Biol Chem (2002) 0.89
A mechanism of Munc18b-syntaxin 3-SNAP25 complex assembly in regulated epithelial secretion. FEBS Lett (2007) 0.88
Automatic validation of phosphopeptide identifications by the MS2/MS3 target-decoy search strategy. J Proteome Res (2008) 0.88
Chromatin protein HP1 interacts with the mitotic regulator borealin protein and specifies the centromere localization of the chromosomal passenger complex. J Biol Chem (2014) 0.87
PinX1 is recruited to the mitotic chromosome periphery by Nucleolin and facilitates chromosome congression. Biochem Biophys Res Commun (2009) 0.87
mtDNA sequence variants in subtypes of epithelial ovarian cancer stages in relation to ethnic and age difference. Diagn Pathol (2008) 0.87
Clinical effects of Xinmailong therapy in patients with chronic heart failure. Int J Med Sci (2013) 0.87
Development and application of a double-antigen sandwich enzyme-linked immunosorbent assay for detection of antibodies to porcine circovirus 2. Clin Vaccine Immunol (2012) 0.87
A better block partition and ligation strategy for individual haplotyping. Bioinformatics (2008) 0.86
FBXL5 interacts with p150Glued and regulates its ubiquitination. Biochem Biophys Res Commun (2007) 0.86
Proteome-wide prediction of PKA phosphorylation sites in eukaryotic kingdom. Genomics (2008) 0.86
Use of DNA methylation for cancer detection: promises and challenges. Int J Biochem Cell Biol (2008) 0.86