Richard I Gregory

Author PubWeight™ 94.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Selective blockade of microRNA processing by Lin28. Science 2008 14.39
2 TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 2005 13.44
3 Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol 2009 11.50
4 The Lin28/let-7 axis regulates glucose metabolism. Cell 2011 4.65
5 Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nat Struct Mol Biol 2009 4.41
6 Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem 2008 4.40
7 MicroRNA silencing through RISC recruitment of eIF6. Nature 2007 4.37
8 EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science 2012 3.74
9 The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol Cell 2013 3.27
10 Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell 2011 2.99
11 Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. J Am Soc Nephrol 2008 2.51
12 A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature 2013 2.34
13 Molecular basis for interaction of let-7 microRNAs with Lin28. Cell 2011 2.28
14 How does Lin28 let-7 control development and disease? Trends Cell Biol 2012 2.09
15 The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell 2011 1.95
16 Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7). RNA 2012 1.74
17 Post-transcriptional control of DGCR8 expression by the Microprocessor. RNA 2009 1.67
18 MicroRNA gene regulatory pathways in the establishment and maintenance of ESC identity. Cell Stem Cell 2010 1.53
19 Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation. Nat Commun 2012 1.35
20 Argonaute2 expression is post-transcriptionally coupled to microRNA abundance. RNA 2013 1.15
21 Fetal deficiency of lin28 programs life-long aberrations in growth and glucose metabolism. Stem Cells 2013 1.09
22 Allelic inactivation of the pseudoautosomal gene SYBL1 is controlled by epigenetic mechanisms common to the X and Y chromosomes. Hum Mol Genet 2002 0.98
23 Linking miRNA regulation to BCR-ABL expression: the next dimension. Cancer Cell 2008 0.91
24 Lin28a regulates germ cell pool size and fertility. Stem Cells 2013 0.88
25 The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly. RNA 2013 0.85
26 Absence of functional LIN28B mutations in a large cohort of patients with idiopathic central precocious puberty. Horm Res Paediatr 2012 0.84
27 Identification of small molecule inhibitors of Zcchc11 TUTase activity. RNA Biol 2015 0.84
28 MicroRNA regulation of stem cell fate. Cell Stem Cell 2008 0.83
29 Reconstitution of human RNA interference in budding yeast. Nucleic Acids Res 2011 0.83
30 MicroRNAs and reprogramming. Nat Biotechnol 2011 0.82
31 Autoregulatory mechanisms controlling the Microprocessor. Adv Exp Med Biol 2010 0.82
32 Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype. J Clin Invest 2016 0.80
33 Pumilio turns on microRNA function. Nat Cell Biol 2010 0.75
34 Autoregulatory mechanisms controlling the microprocessor. Adv Exp Med Biol 2011 0.75