Published in PLoS Comput Biol on September 13, 2016
Elements of biological oscillations in time and space. Nat Struct Mol Biol (2016) 0.75
Structure and function of the feed-forward loop network motif. Proc Natl Acad Sci U S A (2003) 12.50
An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A (1981) 10.04
Calcium oscillations increase the efficiency and specificity of gene expression. Nature (1998) 9.19
Cell-signalling dynamics in time and space. Nat Rev Mol Cell Biol (2006) 7.25
Circadian rhythms from multiple oscillators: lessons from diverse organisms. Nat Rev Genet (2005) 6.87
A fast, robust and tunable synthetic gene oscillator. Nature (2008) 6.85
Engineered gene circuits. Nature (2002) 6.25
Defining network topologies that can achieve biochemical adaptation. Cell (2009) 5.49
A synchronized quorum of genetic clocks. Nature (2010) 5.47
Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing. Nature (2010) 5.27
Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature (2002) 5.25
Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science (2005) 5.14
Design principles of biochemical oscillators. Nat Rev Mol Cell Biol (2008) 4.55
Synthetic gene networks that count. Science (2009) 4.54
Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription. Science (2009) 4.14
Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. Proc Natl Acad Sci U S A (2005) 4.11
The incoherent feedforward loop can provide fold-change detection in gene regulation. Mol Cell (2009) 3.38
p53 dynamics control cell fate. Science (2012) 3.30
Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci U S A (2001) 3.02
Encoding and decoding cellular information through signaling dynamics. Cell (2013) 2.96
Oscillatory control of factors determining multipotency and fate in mouse neural progenitors. Science (2013) 2.56
Molecular titration and ultrasensitivity in regulatory networks. J Mol Biol (2008) 2.48
Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals. Mol Cell (2012) 2.11
Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor. Mol Syst Biol (2009) 2.10
Protein sequestration generates a flexible ultrasensitive response in a genetic network. Mol Syst Biol (2009) 2.09
Stimulus-dependent dynamics of p53 in single cells. Mol Syst Biol (2011) 2.02
A TNF-induced gene expression program under oscillatory NF-kappaB control. BMC Genomics (2005) 1.92
Periodic signaling controlled by an oscillatory circuit that includes protein kinases ERK2 and PKA. Science (2004) 1.90
Functional roles of pulsing in genetic circuits. Science (2013) 1.84
Impulse control: temporal dynamics in gene transcription. Cell (2011) 1.79
Cyclic-AMP-controlled oscillations in suspended Dictyostelium cells: their relation to morphogenetic cell interactions. Proc Natl Acad Sci U S A (1974) 1.77
The dark side of a tumor suppressor: anti-apoptotic p53. Cell Death Differ (2008) 1.68
An externally tunable bacterial band-pass filter. Proc Natl Acad Sci U S A (2009) 1.67
Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer. Science (2014) 1.64
Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation. Mol Cell (2013) 1.62
Myc and cell cycle control. Biochim Biophys Acta (2014) 1.44
The biphasic behavior of incoherent feed-forward loops in biomolecular regulatory networks. Bioessays (2008) 1.37
Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells. Cancer Res (2012) 1.29
The utility of paradoxical components in biological circuits. Mol Cell (2013) 1.25
Fold change of nuclear NF-κB determines TNF-induced transcription in single cells. Mol Cell (2014) 1.16
NFIL3 and cAMP response element-binding protein form a transcriptional feedforward loop that controls neuronal regeneration-associated gene expression. J Neurosci (2009) 1.11
Frequency modulation of ERK activation dynamics rewires cell fate. Mol Syst Biol (2015) 1.11
A noisy linear map underlies oscillations in cell size and gene expression in bacteria. Nature (2015) 1.11
The c-MYC-AP4-p21 cascade. Cell Cycle (2009) 1.08
Sensing and integration of Erk and PI3K signals by Myc. PLoS Comput Biol (2008) 1.03
Noise-limited frequency signal transmission in gene circuits. Biophys J (2007) 0.99
Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A). Mol Cell Biol (2012) 0.98
Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisions. Development (2014) 0.92
cAMP-responsive element-binding protein (CREB) and cAMP co-regulate activator protein 1 (AP1)-dependent regeneration-associated gene expression and neurite growth. J Biol Chem (2014) 0.88
Simple molecular networks that respond optimally to time-periodic stimulation. BMC Syst Biol (2009) 0.84
Logarithmic and power law input-output relations in sensory systems with fold-change detection. PLoS Comput Biol (2014) 0.83
Accurate encoding and decoding by single cells: amplitude versus frequency modulation. PLoS Comput Biol (2015) 0.81
Dynamic expression and roles of Hes factors in neural development. Cell Tissue Res (2014) 0.80
Computational analysis of signaling patterns in single cells. Semin Cell Dev Biol (2014) 0.78
Genetic regulatory networks that count to 3. J Theor Biol (2013) 0.76