[The clinical detection of breast cancer by spectrum method].

APD2: the updated antimicrobial peptide database and its application in peptide design. Nucleic Acids Res (2008) 4.23

Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation. Immunity (2011) 3.75

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68

A high-resolution map of segmental DNA copy number variation in the mouse genome. PLoS Genet (2006) 3.24

China: the aging giant. J Am Geriatr Soc (2007) 2.89

Towards precise classification of cancers based on robust gene functional expression profiles. BMC Bioinformatics (2005) 2.01

Effect of 6 months of erythromycin treatment on inflammatory cells in induced sputum and exacerbations in chronic obstructive pulmonary disease. Respiration (2010) 2.00

Human immunodeficiency virus type 1 enters brain microvascular endothelia by macropinocytosis dependent on lipid rafts and the mitogen-activated protein kinase signaling pathway. J Virol (2002) 1.97

MiRNA-miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features. Nucleic Acids Res (2010) 1.94

Transmission of MDR and XDR tuberculosis in Shanghai, China. PLoS One (2009) 1.93

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet (2011) 1.92

Brain cannabinoid CB₂ receptors modulate cocaine's actions in mice. Nat Neurosci (2011) 1.88

A nation-wide multicenter 10-year (1999-2008) retrospective clinical epidemiological study of female breast cancer in China. BMC Cancer (2011) 1.88

Major taste loss in carnivorous mammals. Proc Natl Acad Sci U S A (2012) 1.81

The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma. J Clin Invest (2013) 1.76

RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects. Breast Cancer Res Treat (2010) 1.74

trans-Diaqua-bis[5-carb-oxy-4-carboxyl-ato-2-(4-pyridinio)-1H-imidazol-1-ido-κN,O]iron(II). Acta Crystallogr Sect E Struct Rep Online (2009) 1.72

Polymorphisms of tumor necrosis factor-alpha and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2010) 1.70

Correlation of iron in the hippocampus with MMSE in patients with Alzheimer's disease. J Magn Reson Imaging (2009) 1.64

High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases. Nucleic Acids Res (2013) 1.61

The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol (2012) 1.60

Comparison of isotropic and orthotropic material property assignments on femoral finite element models under two loading conditions. Med Eng Phys (2005) 1.55

Effect of transcutaneous auricular vagus nerve stimulation on impaired glucose tolerance: a pilot randomized study. BMC Complement Altern Med (2014) 1.54

Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells. Free Radic Biol Med (2002) 1.54

Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience. Cell Transplant (2013) 1.53

Apparently low reproducibility of true differential expression discoveries in microarray studies. Bioinformatics (2008) 1.48

Cross-priming amplification for rapid detection of Mycobacterium tuberculosis in sputum specimens. J Clin Microbiol (2008) 1.47

Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. J Neurosci (2006) 1.46

Prioritizing risk pathways: a novel association approach to searching for disease pathways fusing SNPs and pathways. Bioinformatics (2008) 1.46

Lack of an association between AURKA T91A polymorphisms and breast cancer: a meta-analysis involving 32,141 subjects. Breast Cancer Res Treat (2010) 1.46

SubpathwayMiner: a software package for flexible identification of pathways. Nucleic Acids Res (2009) 1.45

Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice. J Neurosci (2004) 1.43

Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability. J Cell Sci (2004) 1.42

QDMR: a quantitative method for identification of differentially methylated regions by entropy. Nucleic Acids Res (2011) 1.37

Reconstruction for free-space fluorescence tomography using a novel hybrid adaptive finite element algorithm. Opt Express (2007) 1.36

Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeast. EMBO J (2004) 1.34

Disruption of the cellulose synthase gene, AtCesA8/IRX1, enhances drought and osmotic stress tolerance in Arabidopsis. Plant J (2005) 1.34

Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4. Cell Res (2010) 1.33

The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions. Br J Pharmacol (2003) 1.33

The relationship between body mass index and hip osteoarthritis: a systematic review and meta-analysis. Joint Bone Spine (2010) 1.33

Female oxytocin-deficient mice display enhanced anxiety-related behavior. Endocrinology (2003) 1.32

MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer. J Pathol (2014) 1.31

Detection of Escherichia coli, Salmonella spp., Shigella spp., Yersinia enterocolitica, Vibrio cholerae, and Campylobacter spp. enteropathogens by 3-reaction multiplex polymerase chain reaction. Diagn Microbiol Infect Dis (2008) 1.30

Identification and expression analysis of miRNAs from nitrogen-fixing soybean nodules. Biochem Biophys Res Commun (2008) 1.30

A snake-based method for segmentation of intravascular ultrasound images and its in vivo validation. Ultrasonics (2010) 1.30

Correlation of three-dimensional structures with the antibacterial activity of a group of peptides designed based on a nontoxic bacterial membrane anchor. J Biol Chem (2004) 1.30

A robust hybrid between genetic algorithm and support vector machine for extracting an optimal feature gene subset. Genomics (2005) 1.30

Heavy metal sources identification and sampling uncertainty analysis in a field-scale vegetable soil of Hangzhou, China. Environ Pollut (2008) 1.29

The Salt Overly Sensitive (SOS) pathway: established and emerging roles. Mol Plant (2013) 1.28

Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice. Physiol Genomics (2007) 1.28

HHMD: the human histone modification database. Nucleic Acids Res (2009) 1.27

NDRG2 expression and mutation in human liver and pancreatic cancers. World J Gastroenterol (2004) 1.27

Guidelines on the diagnosis and treatment of breast cancer (2011 edition). Gland Surg (2012) 1.25

A comparative study of salt tolerance parameters in 11 wild relatives of Arabidopsis thaliana. J Exp Bot (2010) 1.24

An endoplasmic reticulum response pathway mediates programmed cell death of root tip induced by water stress in Arabidopsis. New Phytol (2010) 1.23

KLF6 induces apoptosis in prostate cancer cells through up-regulation of ATF3. J Biol Chem (2008) 1.23

Cellular uptake of nanoparticles by membrane penetration: a study combining confocal microscopy with FTIR spectroelectrochemistry. ACS Nano (2012) 1.22

Multimodality molecular imaging. IEEE Eng Med Biol Mag (2008) 1.22

Association between NSAIDs use and breast cancer risk: a systematic review and meta-analysis. Breast Cancer Res Treat (2008) 1.22

N-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis. Nucleic Acids Res (2008) 1.22

Umbilical cord mesenchymal stem cell transplantation in active and refractory systemic lupus erythematosus: a multicenter clinical study. Arthritis Res Ther (2014) 1.22

Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropsychopharmacology (2007) 1.21

Influence of cobalamin scarcity on diatom molecular physiology and identification of a cobalamin acquisition protein. Proc Natl Acad Sci U S A (2012) 1.20

Down-regulation of TIPE2 mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Clin Immunol (2009) 1.20

The analysis of the drug-targets based on the topological properties in the human protein-protein interaction network. J Drug Target (2009) 1.20

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment. Integr Biol (Camb) (2013) 1.17

Salt modulates gravity signaling pathway to regulate growth direction of primary roots in Arabidopsis. Plant Physiol (2007) 1.17

Association between embB codon 306 mutations and drug resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother (2007) 1.17

A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis. Arthritis Res Ther (2012) 1.17

A combined fluorescence and microcomputed tomography system for small animal imaging. IEEE Trans Biomed Eng (2010) 1.17

YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice. Addict Biol (2011) 1.16

Gene therapy following subretinal AAV5 vector delivery is not affected by a previous intravitreal AAV5 vector administration in the partner eye. Mol Vis (2009) 1.16

Overexpression of SOS (Salt Overly Sensitive) genes increases salt tolerance in transgenic Arabidopsis. Mol Plant (2008) 1.16

IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma. Neuro Oncol (2013) 1.15

Is K-ras gene mutation a prognostic factor for colorectal cancer: a systematic review and meta-analysis. Dis Colon Rectum (2012) 1.15

Unravelling the hidden heterogeneities of diffuse large B-cell lymphoma based on coupled two-way clustering. BMC Genomics (2007) 1.15

H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin. Genes Dev (2013) 1.14

Science and Government. Reforming China's S&T system. Science (2013) 1.14

Accuracy of image registration between MRI and light microscopy in the ex vivo brain. Magn Reson Imaging (2011) 1.14

Arabidopsis EIN2 modulates stress response through abscisic acid response pathway. Plant Mol Biol (2007) 1.14

Prioritizing candidate disease miRNAs by topological features in the miRNA target-dysregulated network: case study of prostate cancer. Mol Cancer Ther (2011) 1.14

Inhibition of aberrant circulating Tfh cell proportions by corticosteroids in patients with systemic lupus erythematosus. PLoS One (2012) 1.13

Atlas-based fuzzy connectedness segmentation and intensity nonuniformity correction applied to brain MRI. IEEE Trans Biomed Eng (2007) 1.13

Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study. Hum Genet (2007) 1.12

Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. J Neurochem (2009) 1.11

Loci on chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains. Mamm Genome (2003) 1.11

Comprehensive analysis of the functional microRNA-mRNA regulatory network identifies miRNA signatures associated with glioma malignant progression. Nucleic Acids Res (2013) 1.11

Breast cancer stage at diagnosis and area-based socioeconomic status: a multicenter 10-year retrospective clinical epidemiological study in China. BMC Cancer (2012) 1.11

Increased neutrophilia in nasal polyps reduces the response to oral corticosteroid therapy. J Allergy Clin Immunol (2012) 1.10

Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures. Mol Cell Biol (2004) 1.10

A Wnt-Frz/Ror-Dsh pathway regulates neurite outgrowth in Caenorhabditis elegans. PLoS Genet (2010) 1.09

Combined deficiency of vitamins E and C causes paralysis and death in guinea pigs. Am J Clin Nutr (2003) 1.09

Isolation and characterization of Methanoculleus receptaculi sp. nov. from Shengli oil field, China. FEMS Microbiol Lett (2008) 1.09

Prevalence of fluoroquinolone resistance among tuberculosis patients in Shanghai, China. Antimicrob Agents Chemother (2009) 1.09

SM2miR: a database of the experimentally validated small molecules' effects on microRNA expression. Bioinformatics (2012) 1.08

Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, China. Antimicrob Agents Chemother (2009) 1.08

Clinical manifestations of dermatomyositis and clinically amyopathic dermatomyositis patients with positive expression of anti-melanoma differentiation-associated gene 5 antibody. Arthritis Care Res (Hoboken) (2012) 1.08

Finding a role for leptin in the regulation of the Th17 response in experimental arthritis: comment on the article by Deng et al. Arthritis Rheum (2013) 1.08