PubRank

Eiki Kominami

Author PubWeight™ 229.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006 21.40
2 Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2007 20.92
3 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
4 Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 2005 18.60
5 Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 2007 14.63
6 Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy 2005 7.33
7 The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 2010 6.95
8 LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2004 6.34
9 Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet. Cell Metab 2008 5.55
10 Role for Rab7 in maturation of late autophagic vacuoles. J Cell Sci 2004 5.19
11 Structural basis for sorting mechanism of p62 in selective autophagy. J Biol Chem 2008 4.20
12 Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proc Natl Acad Sci U S A 2007 3.92
13 The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice. Mol Biol Cell 2008 3.72
14 LC3 and Autophagy. Methods Mol Biol 2008 3.59
15 Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J Cell Biol 2009 2.83
16 Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p. J Biol Chem 2002 2.66
17 HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. J Biol Chem 2004 2.58
18 Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury. Am J Pathol 2008 2.57
19 Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). Am J Pathol 2005 2.56
20 Excess peroxisomes are degraded by autophagic machinery in mammals. J Biol Chem 2005 2.44
21 The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting. J Biol Chem 2003 2.19
22 Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16. J Biol Chem 2005 2.14
23 Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. J Biol Chem 2004 2.10
24 Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes. J Biol Chem 2004 2.01
25 A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier. EMBO J 2004 1.99
26 The MAP1-LC3 conjugation system is involved in lipid droplet formation. Biochem Biophys Res Commun 2009 1.77
27 Selective turnover of p62/A170/SQSTM1 by autophagy. Autophagy 2008 1.71
28 MAP-LC3, a promising autophagosomal marker, is processed during the differentiation and recovery of podocytes from PAN nephrosis. FASEB J 2003 1.64
29 Lysosomal turnover of GABARAP-phospholipid conjugate is activated during differentiation of C2C12 cells to myotubes without inactivation of the mTor kinase-signaling pathway. Autophagy 2006 1.60
30 Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles. Autophagy 2009 1.60
31 Liver autophagy contributes to the maintenance of blood glucose and amino acid levels. Autophagy 2011 1.59
32 Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. J Immunol 2003 1.50
33 A novel type of E3 ligase for the Ufm1 conjugation system. J Biol Chem 2009 1.47
34 Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls. Autophagy 2007 1.45
35 Processing and activation of lysosomal proteinases. Biol Chem 2002 1.44
36 The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification. J Biol Chem 2003 1.44
37 Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. J Biol Chem 2005 1.36
38 The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers. J Mol Biol 2005 1.34
39 Multiple pathways of TWEAK-induced cell death. J Immunol 2002 1.32
40 GATE-16 and GABARAP are authentic modifiers mediated by Apg7 and Apg3. Biochem Biophys Res Commun 2003 1.30
41 Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading. Mol Cell Biol 2009 1.27
42 Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation. Hum Mol Genet 2002 1.24
43 Crucial role for autophagy in degranulation of mast cells. J Allergy Clin Immunol 2011 1.23
44 Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway. Biochem Biophys Res Commun 2010 1.21
45 Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice. Mol Cell Neurosci 2003 1.21
46 CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis. Genes Cells 2002 1.20
47 Comprehensive proteomics analysis of autophagy-deficient mouse liver. Biochem Biophys Res Commun 2008 1.18
48 LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. Biochem Biophys Res Commun 2010 1.18
49 Skeletal muscle gene expression in space-flown rats. FASEB J 2004 1.18
50 Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates. Hippocampus 2003 1.15
51 Atg8L/Apg8L is the fourth mammalian modifier of mammalian Atg8 conjugation mediated by human Atg4B, Atg7 and Atg3. FEBS J 2006 1.12
52 Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation. Autophagy 2008 1.11
53 Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy. J Gastroenterol 2009 1.08
54 Inflammatory response and cathepsins in silica-exposed Hermansky-Pudlak syndrome model pale ear mice. Pathol Int 2004 1.07
55 Autophagic compartments gain access to the MHC class II compartments in thymic epithelium. J Immunol 2009 1.03
56 Autophagy and neurodegeneration. Autophagy 2006 1.03
57 Monoubiquitylation of GGA3 by hVPS18 regulates its ubiquitin-binding ability. Biochem Biophys Res Commun 2006 1.01
58 Selective modulation of the secretion of proteinases and their inhibitors by growth factors in cultured differentiated podocytes. Kidney Int 2002 0.99
59 Phospholipase C-related inactive protein is involved in trafficking of gamma2 subunit-containing GABA(A) receptors to the cell surface. J Neurosci 2007 0.99
60 Neuronal ceroid lipofuscinosis: a common pathway? Pediatr Res 2007 0.96
61 Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing. Biochem Biophys Res Commun 2002 0.96
62 The intracellular location and function of proteins of neuronal ceroid lipofuscinoses. Brain Pathol 2004 0.95
63 Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1. Biochem Biophys Res Commun 2006 0.95
64 Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein. J Neurochem 2003 0.95
65 Dendrin location in podocytes is associated with disease progression in animal and human glomerulopathy. Am J Nephrol 2011 0.94
66 Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation. Autophagy 2009 0.94
67 Immunohistochemical characterization of the intracellular pool of water channel aquaporin-2 in the rat kidney. Anat Sci Int 2002 0.93
68 Crystal structure of Ufc1, the Ufm1-conjugating enzyme. Biochem Biophys Res Commun 2007 0.92
69 Role for gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelial cells. Infect Immun 2007 0.90
70 Identification of mouse Vps16 and biochemical characterization of mammalian class C Vps complex. Biochem Biophys Res Commun 2003 0.90
71 Peroxisome degradation in mammals. IUBMB Life 2011 0.88
72 Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition. Acta Neuropathol 2002 0.86
73 The carboxyl terminal 17 amino acids within Apg7 are essential for Apg8 lipidation, but not for Apg12 conjugation. FEBS Lett 2003 0.84
74 Metabolic contribution of hepatic autophagic proteolysis: old wine in new bottles. Biochim Biophys Acta 2011 0.81
75 Sulfhydryl oxidase (SOx) from mouse epidermis: molecular cloning, nucleotide sequence, and expression of recombinant protein in the cultured cells. J Dermatol Sci 2002 0.80
76 Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs. Biochem Biophys Res Commun 2002 0.80
77 Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system. Eur J Neurosci 2012 0.79
78 Mutation of the glycosylated asparagine residue 286 in human CLN2 protein results in loss of enzymatic activity. Glycobiology 2004 0.79
79 Proteinases participating in the processing and activation of prolegumain in primary cultured rat macrophages. Biol Chem 2004 0.79
80 Method for monitoring pexophagy in mammalian cells. Methods Enzymol 2009 0.79
81 The expression of tripeptidyl peptidase I in various tissues of rats and mice. Arch Histol Cytol 2002 0.78
82 Doxorubicin-induced glomerulosclerosis with proteinuria in GFP-GABARAP transgenic mice. Am J Physiol Renal Physiol 2011 0.78
83 Differentiation-specific expression and localization of an autophagosomal marker protein (LC3) in human epidermal keratinocytes. J Dermatol Sci 2008 0.78
84 Changes in the distribution and density of caveolin 3 molecules at the plasma membrane of mdx mouse skeletal muscles: a fracture-label electron microscopic study. Neurosci Lett 2002 0.77
85 Expression of cathepsin H in differentiating rat spermatids: immunoelectron microscopic study. Histochem Cell Biol 2003 0.77
86 The interaction of mammalian Class C Vps with nSec-1/Munc18-a and syntaxin 1A regulates pre-synaptic release. Biochem Biophys Res Commun 2006 0.77
87 Hepatic gap junctions in the hepatocarcinogen-resistant DRH rat. Histochem Cell Biol 2008 0.76
88 Characterization of CAA0225, a novel inhibitor specific for cathepsin L, as a probe for autophagic proteolysis. Biol Pharm Bull 2009 0.76
89 Enrichment of GABARAP relative to LC3 in the axonal initial segments of neurons. PLoS One 2013 0.75
90 [Autophagy and neurodegenerative diseases]. Tanpakushitsu Kakusan Koso 2006 0.75
91 [International standard education]. Seikagaku 2014 0.75
92 In vitro assays of lipidation of Mammalian atg8 homologs. Curr Protoc Cell Biol 2014 0.75
93 1H, 13C, and 15N resonance assignments of human microtubule-associated protein light chain-3. J Biomol NMR 2004 0.75
94 [Autophagic-lysosomal system: physiology and pathology]. Nihon Shinkei Seishin Yakurigaku Zasshi 2006 0.75