Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals.

PubWeight™: 3.27‹?› | Rank: Top 1%

🔗 View Article (PMC 2664036)

Published in Proc Natl Acad Sci U S A on March 16, 2009

Authors

Flavia Bazzoni1, Marzia Rossato, Marco Fabbri, Daniele Gaudiosi, Massimiliano Mirolo, Laura Mori, Nicola Tamassia, Alberto Mantovani, Marco A Cassatella, Massimo Locati

Author Affiliations

1: Department of Pathology, Division of General Pathology, University of Verona, Strada le Grazie 8, I-37134 Verona, Italy.

Articles citing this

(truncated to the top 100)

Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 13.44

Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol (2010) 7.75

Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol (2011) 6.96

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol (2009) 5.05

The complexity of NF-κB signaling in inflammation and cancer. Mol Cancer (2013) 4.20

miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J Exp Med (2011) 3.78

Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis (2009) 3.40

Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study. J Clin Oncol (2009) 2.78

miR-146a is critical for endotoxin-induced tolerance: IMPLICATION IN INNATE IMMUNITY. J Biol Chem (2009) 2.68

MicroRNAs in NF-kappaB signaling. J Mol Cell Biol (2011) 2.50

NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses. PLoS Pathog (2009) 2.32

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease. Proc Natl Acad Sci U S A (2009) 2.28

microRNAs and the immune response. Curr Opin Pharmacol (2009) 2.18

MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases. Transl Res (2011) 2.15

Proinflammatory role for let-7 microRNAS in experimental asthma. J Biol Chem (2010) 2.08

Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J Immunol (2009) 1.93

MicroRNA in TLR signaling and endotoxin tolerance. Cell Mol Immunol (2011) 1.86

Identifying functional microRNAs in macrophages with polarized phenotypes. J Biol Chem (2012) 1.67

Molecular mechanisms that influence the macrophage m1-m2 polarization balance. Front Immunol (2014) 1.62

Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling. J Immunol (2010) 1.58

Antagonism of miR-328 increases the antimicrobial function of macrophages and neutrophils and rapid clearance of non-typeable Haemophilus influenzae (NTHi) from infected lung. PLoS Pathog (2015) 1.48

MicroRNAs in immune response and macrophage polarization. Arterioscler Thromb Vasc Biol (2013) 1.48

The role of toll-like receptors in rheumatoid arthritis. Curr Rheumatol Rep (2009) 1.44

MicroRNAs: master regulators of ethanol abuse and toxicity? Alcohol Clin Exp Res (2010) 1.44

A miR-19 regulon that controls NF-κB signaling. Nucleic Acids Res (2012) 1.43

Important aspects of Toll-like receptors, ligands and their signaling pathways. Inflamm Res (2010) 1.40

Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD). Int J Biochem Mol Biol (2012) 1.37

Estradiol suppresses NF-kappa B activation through coordinated regulation of let-7a and miR-125b in primary human macrophages. J Immunol (2010) 1.32

MiR-146a in Immunity and Disease. Mol Biol Int (2011) 1.28

NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells. Exp Neurol (2011) 1.26

Neutrophil-derived cytokines: facts beyond expression. Front Immunol (2014) 1.25

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b. Proc Natl Acad Sci U S A (2013) 1.25

MicroRNAs in inflammatory lung disease--master regulators or target practice? Respir Res (2010) 1.24

IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes. Proc Natl Acad Sci U S A (2012) 1.24

MicroRNA-mediated control of macrophages and its implications for cancer. Trends Immunol (2013) 1.22

The Roles of MicroRNAs in the Cancer Invasion-Metastasis Cascade. Cancer Microenviron (2010) 1.21

MicroRNAs in inflammatory bowel disease. Inflamm Bowel Dis (2011) 1.19

MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes. J Immunol (2011) 1.18

microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus. Sci Rep (2013) 1.18

Porphyromonas gingivalis induction of microRNA-203 expression controls suppressor of cytokine signaling 3 in gingival epithelial cells. Infect Immun (2011) 1.18

miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFκB1. Exp Mol Med (2011) 1.15

Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40. J Immunol (2011) 1.14

MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling. Age (Dordr) (2012) 1.13

Evidence for microRNA involvement in exercise-associated neutrophil gene expression changes. J Appl Physiol (1985) (2010) 1.13

MicroRNAs: new regulators of Toll-like receptor signalling pathways. Biomed Res Int (2014) 1.11

MicroRNA regulation of innate immune responses in epithelial cells. Cell Mol Immunol (2011) 1.11

Integrating microRNAs into a system biology approach to acute lung injury. Transl Res (2011) 1.10

NF-κB and cancer: a paradigm of Yin-Yang. Am J Cancer Res (2010) 1.08

NF-kappaB P50/P65 hetero-dimer mediates differential regulation of CD166/ALCAM expression via interaction with micoRNA-9 after serum deprivation, providing evidence for a novel negative auto-regulatory loop. Nucleic Acids Res (2011) 1.07

MicroRNAs: new players in IBD. Gut (2014) 1.07

MicroRNA expression in human retinal pigment epithelial (ARPE-19) cells: increased expression of microRNA-9 by N-(4-hydroxyphenyl)retinamide. Mol Vis (2010) 1.06

Circulating inflamma-miRs in aging and age-related diseases. Front Genet (2013) 1.06

Pharmacological studies of the mechanism and function of interleukin-1beta-induced miRNA-146a expression in primary human airway smooth muscle. Respir Res (2010) 1.05

Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene (2012) 1.04

MicroRNAs as Haematopoiesis Regulators. Adv Hematol (2013) 1.03

Studying micro RNA Function and Dysfunction in Alzheimer's Disease. Front Genet (2013) 1.03

Species-specific microRNA roles elucidated following astrocyte activation. Nucleic Acids Res (2011) 1.02

Role of microRNAs in the immune system, inflammation and cancer. World J Gastroenterol (2013) 1.02

Regulation of miRNA biogenesis and turnover in the immune system. Immunol Rev (2013) 1.00

TIR8/SIGIRR is an Interleukin-1 Receptor/Toll Like Receptor Family Member with Regulatory Functions in Inflammation and Immunity. Front Immunol (2012) 0.99

Antagonism of NF-κB-up-regulated micro RNAs (miRNAs) in sporadic Alzheimer's disease (AD)-anti-NF-κB vs. anti-miRNA strategies. Front Genet (2013) 0.99

MicroRNA dysregulation in the spinal cord following traumatic injury. PLoS One (2012) 0.98

Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity. Cancer Res (2014) 0.98

MicroRNA expression profile in human macrophages in response to Leishmania major infection. PLoS Negl Trop Dis (2013) 0.98

Listeria monocytogenes infection in macrophages induces vacuolar-dependent host miRNA response. PLoS One (2011) 0.97

Interplay between DNA repair and inflammation, and the link to cancer. Crit Rev Biochem Mol Biol (2014) 0.96

Decoys and Regulatory "Receptors" of the IL-1/Toll-Like Receptor Superfamily. Front Immunol (2013) 0.96

Epigenetic targets for reversing immune defects caused by alcohol exposure. Alcohol Res (2013) 0.96

Translation control: a multifaceted regulator of inflammatory response. J Immunol (2010) 0.95

MicroRNAs and toll-like receptor/interleukin-1 receptor signaling. J Hematol Oncol (2012) 0.95

MicroRNAs and Multiple Sclerosis. Autoimmune Dis (2010) 0.94

MiR-9 promotes microglial activation by targeting MCPIP1. Nat Commun (2014) 0.94

Critical role of miR-9 in myelopoiesis and EVI1-induced leukemogenesis. Proc Natl Acad Sci U S A (2013) 0.94

Understanding Alcoholism Through microRNA Signatures in Brains of Human Alcoholics. Front Genet (2012) 0.94

MicroRNA-9 regulates the expression of peroxisome proliferator-activated receptor δ in human monocytes during the inflammatory response. Int J Mol Med (2013) 0.93

MicroRNAs as pharmacological targets in endothelial cell function and dysfunction. Pharmacol Res (2013) 0.92

M3 subtype of muscarinic acetylcholine receptor promotes cardioprotection via the suppression of miR-376b-5p. PLoS One (2012) 0.92

MicroRNAs in the regulation of TLR and RIG-I pathways. Cell Mol Immunol (2012) 0.92

Pulmonary microRNA profiling in a mouse model of ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol (2012) 0.92

miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun (2015) 0.91

Regulation of neutrophil senescence by microRNAs. PLoS One (2011) 0.91

MicroRNA dysregulation in spinal cord injury: causes, consequences and therapeutics. Front Cell Neurosci (2014) 0.91

microRNA-mediated regulation of innate immune response in rheumatic diseases. Arthritis Res Ther (2013) 0.91

MicroRNA expressions associated with progression of prostate cancer cells to antiandrogen therapy resistance. Mol Cancer (2014) 0.90

MicroRNA-146a is upregulated by and negatively regulates TLR2 signaling. PLoS One (2013) 0.90

Mechanical stress induces pre-B-cell colony-enhancing factor/NAMPT expression via epigenetic regulation by miR-374a and miR-568 in human lung endothelium. Am J Respir Cell Mol Biol (2014) 0.90

Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6. J Immunol (2014) 0.89

Noncoding RNAs regulate NF-κB signaling to modulate blood vessel inflammation. Front Genet (2014) 0.89

SIV replication is directly downregulated by four antiviral miRNAs. Retrovirology (2013) 0.89

MicroRNA profiling in human neutrophils during bone marrow granulopoiesis and in vivo exudation. PLoS One (2013) 0.88

Downregulation of PCAF by miR-181a/b provides feedback regulation to TNF-α-induced transcription of proinflammatory genes in liver epithelial cells. J Immunol (2012) 0.88

MicroRNAs as novel regulators of neuroinflammation. Mediators Inflamm (2013) 0.88

TGF-β conditions intestinal T cells to express increased levels of miR-155, associated with down-regulation of IL-2 and itk mRNA. Mucosal Immunol (2012) 0.88

MicroRNA regulation of nonmuscle myosin light chain kinase expression in human lung endothelium. Am J Respir Cell Mol Biol (2013) 0.88

A multi-targeted approach to suppress tumor-promoting inflammation. Semin Cancer Biol (2015) 0.87

Suppression and epigenetic regulation of MiR-9 contributes to ethanol teratology: evidence from zebrafish and murine fetal neural stem cell models. Alcohol Clin Exp Res (2013) 0.87

miRNAs as potential therapeutic targets for age-related macular degeneration. Future Med Chem (2012) 0.87

Regulation of activation-associated microRNA accumulation rates during monocyte-to-macrophage differentiation. J Biol Chem (2014) 0.87

MicroRNAs in lupus. Autoimmunity (2014) 0.87

MicroRNA Cargo of Extracellular Vesicles from Alcohol-exposed Monocytes Signals Naive Monocytes to Differentiate into M2 Macrophages. J Biol Chem (2015) 0.86

Articles cited by this

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27

MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59

The functions of animal microRNAs. Nature (2004) 64.85

Prediction of mammalian microRNA targets. Cell (2003) 53.70

Combinatorial microRNA target predictions. Nat Genet (2005) 50.48

Pathogen recognition and innate immunity. Cell (2006) 44.14

Toll-like receptor signalling. Nat Rev Immunol (2004) 34.74

Human MicroRNA targets. PLoS Biol (2004) 34.51

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A (2006) 21.58

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol (1998) 21.48

Nuclear factor-kappaB in cancer development and progression. Nature (2006) 18.31

Requirement of bic/microRNA-155 for normal immune function. Science (2007) 16.24

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol (2004) 15.15

Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet (2004) 12.97

Regulation of the germinal center response by microRNA-155. Science (2007) 12.25

MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci U S A (2007) 11.42

Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol (2005) 9.70

MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell (2007) 9.33

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell (2005) 9.22

Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol (2007) 8.05

T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J Exp Med (2005) 5.26

A viral microRNA functions as an orthologue of cellular miR-155. Nature (2007) 5.09

MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation. Nat Cell Biol (2007) 4.02

How Toll-like receptors signal: what we know and what we don't know. Curr Opin Immunol (2005) 3.40

MicroRNAs and immunity: tiny players in a big field. Immunity (2007) 3.01

Rapid changes in microRNA-146a expression negatively regulate the IL-1beta-induced inflammatory response in human lung alveolar epithelial cells. J Immunol (2008) 2.95

p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res (2006) 2.76

MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary. Nat Neurosci (2008) 2.65

MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells. J Biol Chem (2006) 2.29

NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages. J Biol Chem (2006) 2.29

MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components. Mol Immunol (2007) 2.24

Control of protein synthesis and mRNA degradation by microRNAs. Curr Opin Cell Biol (2008) 2.00

MicroRNA detection by northern blotting using locked nucleic acid probes. Nat Protoc (2008) 1.87

Nuclear factor-kappaB1: regulation and function. Int J Biochem Cell Biol (2007) 1.74

MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas. Am J Pathol (2008) 1.57

Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. J Immunol (2008) 1.29

CROC-4: a novel brain specific transcriptional activator of c-fos expressed from proliferation through to maturation of multiple neuronal cell types. Mol Cell Neurosci (2000) 1.24

Up-regulation of IL-10R1 expression is required to render human neutrophils fully responsive to IL-10. J Immunol (2001) 1.12

The MyD88-independent pathway is not mobilized in human neutrophils stimulated via TLR4. J Immunol (2007) 1.05

Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR. J Leukoc Biol (2003) 0.98

Articles by these authors

The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol (2004) 19.38

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol (2002) 17.85

Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 13.44

Macrophage activation and polarization. Front Biosci (2008) 11.17

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol (2006) 9.82

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol (2010) 9.59

Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell (2005) 9.06

Gene therapy for immunodeficiency due to adenosine deaminase deficiency. N Engl J Med (2009) 8.20

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis (2009) 7.55

Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol (2011) 6.96

Macrophage polarization comes of age. Immunity (2005) 5.67

Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer (2006) 5.60

Macrophage polarization in tumour progression. Semin Cancer Biol (2008) 4.62

Macrophage plasticity and polarization in tissue repair and remodelling. J Pathol (2012) 4.30

The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit Rev Oncol Hematol (2007) 3.95

Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids. J Exp Med (2003) 3.91

Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13. J Immunol (2005) 3.87

A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). Blood (2005) 3.85

Regulation of the chemokine receptor CXCR4 by hypoxia. J Exp Med (2003) 3.71

Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. Annu Rev Immunol (2005) 3.48

IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation. Trends Immunol (2003) 3.41

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol Rev (2008) 3.33

The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo. J Immunol (2004) 3.21

Cancer: Inflaming metastasis. Nature (2009) 3.09

Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation. N Engl J Med (2014) 3.08

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A (2009) 3.01

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response. Nature (2002) 3.01

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nat Immunol (2011) 2.99

New vistas on macrophage differentiation and activation. Eur J Immunol (2007) 2.99

Tuning inflammation and immunity by chemokine sequestration: decoys and more. Nat Rev Immunol (2006) 2.92

Cancer related inflammation: the macrophage connection. Cancer Lett (2008) 2.88

Macrophage diversity and polarization in atherosclerosis: a question of balance. Arterioscler Thromb Vasc Biol (2009) 2.80

p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res (2006) 2.76

Evidence for a cross-talk between human neutrophils and Th17 cells. Blood (2009) 2.75

Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells. J Immunol (2005) 2.75

The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps. J Exp Med (2007) 2.71

An integrated view of humoral innate immunity: pentraxins as a paradigm. Annu Rev Immunol (2010) 2.71

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy. J Clin Invest (2007) 2.63

Regulation of leukocyte recruitment by the long pentraxin PTX3. Nat Immunol (2010) 2.60

The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood (2003) 2.57

CD3+ cells at the invasive margin of deeply invading (pT3-T4) colorectal cancer and risk of post-surgical metastasis: a longitudinal study. Lancet Oncol (2009) 2.47

Cancer-related inflammation: common themes and therapeutic opportunities. Semin Cancer Biol (2011) 2.45

Role of macrophage targeting in the antitumor activity of trabectedin. Cancer Cell (2013) 2.35

Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4. Cancer Res (2004) 2.31

Prognostic significance of the long pentraxin PTX3 in acute myocardial infarction. Circulation (2004) 2.31

G-CSF-stimulated neutrophils are a prominent source of functional BLyS. J Exp Med (2003) 2.31

Cross-linking of the mannose receptor on monocyte-derived dendritic cells activates an anti-inflammatory immunosuppressive program. J Immunol (2003) 2.24

Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Hum Immunol (2009) 2.19

Cardioprotective function of the long pentraxin PTX3 in acute myocardial infarction. Circulation (2008) 2.18

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood (2013) 2.14

Deficiency of the long pentraxin PTX3 promotes vascular inflammation and atherosclerosis. Circulation (2009) 2.11

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev (2013) 2.11

Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility. J Immunol (2010) 2.07

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury. Proc Natl Acad Sci U S A (2004) 2.06

Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer. Cancer Microenviron (2010) 1.96

Pathways connecting inflammation and cancer. Curr Opin Genet Dev (2008) 1.95

Orchestration of metabolism by macrophages. Cell Metab (2012) 1.92

Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation. J Immunol (2002) 1.89

Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy. Blood (2009) 1.88

Tumor associated macrophages and neutrophils in cancer. Immunobiology (2013) 1.87

Chemokines and chemokine receptors: an overview. Front Biosci (Landmark Ed) (2009) 1.87

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors. Immunity (2005) 1.86

Chemokine/chemokine receptor nomenclature. J Interferon Cytokine Res (2002) 1.86

Cytokines as a key component of cancer-related inflammation. Cytokine (2008) 1.85

Cancer: inflammation by remote control. Nature (2005) 1.85

Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology. Blood (2011) 1.84

Production of the long pentraxin PTX3 in advanced atherosclerotic plaques. Arterioscler Thromb Vasc Biol (2002) 1.82

IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection. Microbes Infect (2004) 1.82

IL-1 family nomenclature. Nat Immunol (2010) 1.79

Cellular and molecular pathways linking inflammation and cancer. Immunobiology (2009) 1.78

Long pentraxin 3, a key component of innate immunity, is modulated by high-density lipoproteins in endothelial cells. Arterioscler Thromb Vasc Biol (2008) 1.76

Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality. Intensive Care Med (2010) 1.75

The chemokine system in cancer biology and therapy. Cytokine Growth Factor Rev (2009) 1.75

Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft. J Invest Dermatol (2007) 1.75

Tumor associated macrophages and neutrophils in tumor progression. J Cell Physiol (2013) 1.74

Establishment of a high sensitivity plasma assay for human pentraxin3 as a marker for unstable angina pectoris. Arterioscler Thromb Vasc Biol (2006) 1.72

Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene. Proc Natl Acad Sci U S A (2005) 1.70

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization. Development (2004) 1.68

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res (2010) 1.68

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood (2002) 1.67

Biochemical and functional characterization of the interaction between pentraxin 3 and C1q. Eur J Immunol (2003) 1.67

Macrophage activation and polarization as an adaptive component of innate immunity. Adv Immunol (2013) 1.67

Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proc Natl Acad Sci U S A (2004) 1.66

Differential regulation of iron homeostasis during human macrophage polarized activation. Eur J Immunol (2010) 1.64

Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2). J Leukoc Biol (2006) 1.63