Published in Chem Biol on April 24, 2009
Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol (2010) 2.88
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase. J Cell Biol (2010) 2.51
The extended PP1 toolkit: designed to create specificity. Trends Biochem Sci (2010) 2.51
Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E. Cell (2010) 2.00
KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint. Curr Biol (2011) 1.98
Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev (2009) 1.91
Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors. Dev Cell (2011) 1.68
Spindle assembly checkpoint: the third decade. Philos Trans R Soc Lond B Biol Sci (2011) 1.68
Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients. J Am Coll Cardiol (2015) 1.57
Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites. Nat Struct Mol Biol (2010) 1.56
UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages. PLoS Pathog (2016) 1.40
Making an effective switch at the kinetochore by phosphorylation and dephosphorylation. Chromosoma (2013) 1.39
Signalling scaffolds and local organization of cellular behaviour. Nat Rev Mol Cell Biol (2015) 1.35
A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B. J Cell Biol (2012) 1.27
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. J Cell Biol (2012) 1.26
Structural basis for protein phosphatase 1 regulation and specificity. FEBS J (2012) 1.26
Crosstalk of the EphA2 receptor with a serine/threonine phosphatase suppresses the Akt-mTORC1 pathway in cancer cells. Cell Signal (2010) 1.08
The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity. Mol Cell (2014) 1.04
SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1. Sci Signal (2010) 1.03
Tensin1 requires protein phosphatase-1alpha in addition to RhoGAP DLC-1 to control cell polarization, migration, and invasion. J Biol Chem (2009) 1.02
Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription. J Biol Chem (2010) 1.02
Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery. Elife (2014) 1.00
Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1. Mol Cell Biochem (2010) 1.00
Overcoming inhibition in the spindle checkpoint. Genes Dev (2009) 0.99
What goes on must come off: phosphatases gate-crash the DNA damage response. Trends Biochem Sci (2011) 0.97
RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits. Mol Biol Cell (2010) 0.97
Functional diversification of yeast telomere associated protein, Rif1, in higher eukaryotes. BMC Genomics (2012) 0.96
Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation. Hum Mol Genet (2013) 0.94
The molecular basis for substrate specificity of the nuclear NIPP1:PP1 holoenzyme. Structure (2012) 0.94
Identification of AKAP79 as a protein phosphatase 1 catalytic binding protein. Biochemistry (2011) 0.94
SLC7A14 linked to autosomal recessive retinitis pigmentosa. Nat Commun (2014) 0.93
Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases. Dev Cell (2011) 0.93
MiR-125b promotes cell migration and invasion by targeting PPP1CA-Rb signal pathways in gastric cancer, resulting in a poor prognosis. Gastric Cancer (2014) 0.93
Regulation and function of P-Rex family Rac-GEFs. Small GTPases (2015) 0.92
Identification of hypertension susceptibility loci on rat chromosome 12. Hypertension (2012) 0.92
Structural signature of the MYPT1-PP1 interaction. J Am Chem Soc (2010) 0.91
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling. Front Oncol (2015) 0.91
Molecular investigations of the structure and function of the protein phosphatase 1-spinophilin-inhibitor 2 heterotrimeric complex. Biochemistry (2011) 0.90
Trypanosomatid protein phosphatases. Mol Biochem Parasitol (2010) 0.90
A Nucleoporin Docks Protein Phosphatase 1 to Direct Meiotic Chromosome Segregation and Nuclear Assembly. Dev Cell (2016) 0.89
Self-organization of intracellular gradients during mitosis. Cell Div (2010) 0.89
Basis for the isoform-specific interaction of myosin phosphatase subunits protein phosphatase 1c beta and myosin phosphatase targeting subunit 1. J Biol Chem (2009) 0.88
Regulation of protein phosphatase 1 by intrinsically disordered proteins. Biochem Soc Trans (2012) 0.88
Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1. PLoS One (2012) 0.87
1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription. Br J Pharmacol (2014) 0.86
Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2γ bypasses targeting subunit requirement for eIF2α dephosphorylation. Proc Natl Acad Sci U S A (2014) 0.85
Protein phosphatase 1α interacting proteins in the human brain. OMICS (2012) 0.85
A role for PP1/NIPP1 in steering migration of human cancer cells. PLoS One (2012) 0.84
Plasmodium falciparum encodes a conserved active inhibitor-2 for Protein Phosphatase type 1: perspectives for novel anti-plasmodial therapy. BMC Biol (2013) 0.83
Maternal MEMI Promotes Female Meiosis II in Response to Fertilization in Caenorhabditis elegans. Genetics (2016) 0.83
Development of a peptide that selectively activates protein phosphatase-1 in living cells. Angew Chem Int Ed Engl (2012) 0.82
Structural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures. J Biol Chem (2014) 0.81
Protein phosphatase-1α interacts with and dephosphorylates polycystin-1. PLoS One (2012) 0.81
CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. PLoS Genet (2014) 0.81
Microtubule capture by mitotic kinesin centromere protein E (CENP-E). J Biol Chem (2012) 0.81
Plasmodium falciparum inhibitor-3 homolog increases protein phosphatase type 1 activity and is essential for parasitic survival. J Biol Chem (2011) 0.80
Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle. J Physiol (2014) 0.80
The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate. PLoS One (2013) 0.80
Mutation of Elfn1 in mice causes seizures and hyperactivity. PLoS One (2013) 0.79
Analysis of the interactome of the Ser/Thr Protein Phosphatase type 1 in Plasmodium falciparum. BMC Genomics (2016) 0.78
TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network. Biol Open (2013) 0.78
Cellular responses to HSV-1 infection are linked to specific types of alterations in the host transcriptome. Sci Rep (2016) 0.78
Identification of Plasmodium falciparum Translation Initiation eIF2β Subunit: Direct Interaction with Protein Phosphatase Type 1. Front Microbiol (2016) 0.78
Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21. PLoS One (2012) 0.78
Taperin (c9orf75), a mutated gene in nonsyndromic deafness, encodes a vertebrate specific, nuclear localized protein phosphatase one alpha (PP1α) docking protein. Biol Open (2011) 0.78
p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase. J Biol Chem (2015) 0.77
PhosphoTyrosyl phosphatase activator of Plasmodium falciparum: identification of its residues involved in binding to and activation of PP2A. Int J Mol Sci (2014) 0.77
An intriguing shift occurs in the novel protein phosphatase 1 binding partner, TCTEX1D4: evidence of positive selection in a pika model. PLoS One (2013) 0.77
Refined mapping of a hypertension susceptibility locus on rat chromosome 12. Hypertension (2014) 0.77
Folding of Intrinsically Disordered Protein Phosphatase 1 Regulatory Proteins. Curr Phys Chem (2012) 0.76
Conserved residues in the N terminus of lipin-1 are required for binding to protein phosphatase-1c, nuclear translocation, and phosphatidate phosphatase activity. J Biol Chem (2014) 0.76
The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism. Elife (2016) 0.76
Vascular dysfunction precedes hypertension associated with a blood pressure locus on rat chromosome 12. Am J Physiol Heart Circ Physiol (2014) 0.75
TGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapy. J Cell Mol Med (2014) 0.75
Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1). Sci Rep (2017) 0.75
Structure-Function Analysis of PPP1R3D, a Protein Phosphatase 1 Targeting Subunit, Reveals a Binding Motif for 14-3-3 Proteins which Regulates its Glycogenic Properties. PLoS One (2015) 0.75
The germline-enriched Ppp1r36 promotes autophagy. Sci Rep (2016) 0.75
Genome resequencing and bioinformatic analysis of SNP containing candidate genes in the autoimmune vitiligo Smyth line chicken model. BMC Genomics (2014) 0.75
Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells. Elife (2016) 0.75
Suppressors of ipl1-2 in components of a Glc7 phosphatase complex, Cdc48 AAA ATPase, TORC1, and the kinetochore. G3 (Bethesda) (2012) 0.75
Role of myosin light chain phosphatase in cardiac physiology and pathophysiology. J Mol Cell Cardiol (2016) 0.75
Regulating the regulator: Insights into the cardiac protein phosphatase 1 interactome. J Mol Cell Cardiol (2016) 0.75
Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans. MBio (2016) 0.75
Multisite phosphorylation of P-Rex1 by protein kinase C. Oncotarget (2016) 0.75
PAI1: a novel PP1-interacting protein that mediates human plasma's anti-apoptotic effect in endothelial cells. J Cell Mol Med (2017) 0.75
Redirecting SR Protein Nuclear Trafficking Through An Allosteric Platform. J Mol Biol (2017) 0.75
A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells. Nat Commun (2017) 0.75
The Toxoplasma gondii inhibitor-2 regulates protein phosphatase 1 activity through multiple motifs. Parasitol Res (2017) 0.75
The Polycomb group protein EZH2 directly controls DNA methylation. Nature (2005) 13.67
Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev (2004) 3.82
Structure-based assembly of protein complexes in yeast. Science (2004) 2.89
The relationship between sequence and interaction divergence in proteins. J Mol Biol (2003) 2.59
The extended PP1 toolkit: designed to create specificity. Trends Biochem Sci (2010) 2.51
NPP-type ectophosphodiesterases: unity in diversity. Trends Biochem Sci (2005) 2.08
False-positive detection of recombinant human erythropoietin in urine following strenuous physical exercise. Blood (2006) 2.06
Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol (2011) 1.81
Mitotic phosphatases: from entry guards to exit guides. Trends Cell Biol (2009) 1.73
Degeneracy and function of the ubiquitous RVXF motif that mediates binding to protein phosphatase-1. J Biol Chem (2003) 1.72
PP1/Repo-man dephosphorylates mitotic histone H3 at T3 and regulates chromosomal aurora B targeting. Curr Biol (2011) 1.63
MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells. Stem Cells (2013) 1.49
Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement of splicing factor NIPP1. J Biol Chem (2003) 1.46
Protein phosphatase 1 regulates the histone code for long-term memory. J Neurosci (2009) 1.44
Substrate specificity and activity regulation of protein kinase MELK. J Biol Chem (2005) 1.43
Testing for recombinant erythropoietin. Am J Hematol (2008) 1.39
The PP1 binding code: a molecular-lego strategy that governs specificity. FEBS J (2012) 1.38
The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site. FEBS Lett (2003) 1.38
Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing. Hum Mol Genet (2007) 1.33
Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D. J Cell Sci (2005) 1.28
Interactor-mediated nuclear translocation and retention of protein phosphatase-1. J Biol Chem (2004) 1.25
Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells. Mol Cell Biol (2008) 1.23
Signaling by protein phosphatases in the nucleus. Trends Cell Biol (2002) 1.23
Regulator-driven functional diversification of protein phosphatase-1 in eukaryotic evolution. Bioessays (2002) 1.22
Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II. J Biol Chem (2002) 1.14
A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts. Mol Cell Biol (2008) 1.12
Nuclear protein phosphatase-1 regulates HIV-1 transcription. J Biol Chem (2003) 1.12
Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts. PLoS One (2010) 1.12
Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1. J Biol Chem (2002) 1.11
Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein. J Biol Chem (2005) 1.10
Y65C missense mutation in the WW domain of the Golabi-Ito-Hall syndrome protein PQBP1 affects its binding activity and deregulates pre-mRNA splicing. J Biol Chem (2010) 1.09
High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region. Nucleic Acids Res (2010) 1.08
Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2. Biochem J (2004) 1.08
Modulation of purinergic signaling by NPP-type ectophosphodiesterases. Purinergic Signal (2006) 1.07
Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells. Endocrinology (2006) 1.07
Spindle checkpoint silencing: PP1 tips the balance. Curr Biol (2011) 1.07
Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21). J Biol Chem (2009) 1.07
Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175. PLoS One (2011) 1.06
Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor. Biochem J (2007) 1.05
Retracted Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells. J Biol Chem (2013) 1.04
A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3. Biochemistry (2007) 1.04
An essential oligomannosidic glycan chain in the catalytic domain of autotaxin, a secreted lysophospholipase-D. J Biol Chem (2007) 1.04
Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1. J Biol Chem (2002) 1.03
Aurora B defines its own chromosomal targeting by opposing the recruitment of the phosphatase scaffold Repo-Man. Curr Biol (2013) 1.02
Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription. J Biol Chem (2010) 1.02
A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents. FEBS J (2005) 1.01
Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells. Cancer Lett (2009) 1.00
Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump. Proc Natl Acad Sci U S A (2009) 0.99
Geminate structures of African cassava mosaic virus. J Virol (2004) 0.96
PNUTS enhances in vitro chromosome decondensation in a PP1-dependent manner. Biochem J (2005) 0.96
SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1. Biochem J (2004) 0.95
Functional characterization of the non-catalytic ectodomains of the nucleotide pyrophosphatase/phosphodiesterase NPP1. Biochem J (2003) 0.95
4D-networking by mitotic phosphatases. Curr Opin Cell Biol (2013) 0.95
CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90. Retrovirology (2012) 0.95
A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span. J Mol Cell Cardiol (2006) 0.94