Published in J R Soc Med on May 01, 2009
mACTonHEALTH: Psychological Flexibility and Activity Tracker - Protocol (ACTonHEALTH) | NCT03351712
Ecology and transmission of Buruli ulcer disease: a systematic review. PLoS Negl Trop Dis (2010) 2.98
Vitamin D: beyond bone. Ann N Y Acad Sci (2013) 1.39
10 years of mindlines: a systematic review and commentary. Implement Sci (2015) 1.11
Current experience with applying the GRADE approach to public health interventions: an empirical study. BMC Public Health (2013) 1.07
Evidence-based mechanistic reasoning. J R Soc Med (2010) 1.06
Pharmacovigilance. Br J Clin Pharmacol (2012) 0.98
Nutrition issues in Codex: health claims, nutrient reference values and WTO agreements: a conference report. Eur J Nutr (2012) 0.94
Too much sitting and all-cause mortality: is there a causal link? BMC Public Health (2016) 0.88
Markers of inflammation in schizophrenia: association vs. causation. World Psychiatry (2014) 0.86
Observational Evidence of For-Profit Delivery and Inferior Nursing Home Care: When Is There Enough Evidence for Policy Change? PLoS Med (2016) 0.78
Policies to clean up toxic industrial contaminated sites of Gela and Priolo: a cost-benefit analysis. Environ Health (2011) 0.78
A Systematic Review and Meta-analysis of the Timing of Early Intraventricular Hemorrhage in Preterm Neonates: Clinical and Research Implications. J Clin Neonatol (2014) 0.77
Rate of Chiari I malformation in children of mothers with depression with and without prenatal SSRI exposure. Neuropsychopharmacology (2014) 0.77
Study designs and methods post genome-wide association studies. Hum Genet (2012) 0.77
Authors' reply to Whitlock: Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence. CNS Drugs (2014) 0.76
Mortality is associated with inflammation, anemia, specific diseases and treatments, and molecular markers. PLoS One (2017) 0.75
The Obesity Paradox in Kidney Disease: How to Reconcile it with Obesity Management. KI Rep (2017) 0.75
Safety vs. efficacy assessment of pharmaceuticals: Epistemological rationales and methods. Prev Med Rep (2014) 0.75
Therapeutic intervention in oropharyngeal dysphagia. Nat Rev Gastroenterol Hepatol (2016) 0.75
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA (2002) 80.37
THE ENVIRONMENT AND DISEASE: ASSOCIATION OR CAUSATION? Proc R Soc Med (1965) 40.52
The revised CONSORT statement for reporting randomized trials: explanation and elaboration. Ann Intern Med (2001) 37.70
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ (2008) 33.10
Grading quality of evidence and strength of recommendations. BMJ (2004) 26.08
Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ (2004) 24.88
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med (1999) 20.31
Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. Lancet (2004) 18.69
The mortality of doctors in relation to their smoking habits; a preliminary report. Br Med J (1954) 18.11
A comparison of observational studies and randomized, controlled trials. N Engl J Med (2000) 14.11
Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med (1991) 13.91
Reporting of noninferiority and equivalence randomized trials: an extension of the CONSORT statement. JAMA (2006) 11.87
Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study. BMJ (2008) 11.08
Are the clinical effects of homoeopathy placebo effects? Comparative study of placebo-controlled trials of homoeopathy and allopathy. Lancet (2005) 7.89
The periodic health examination. Canadian Task Force on the Periodic Health Examination. Can Med Assoc J (1979) 7.55
Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med (1994) 7.05
When are randomised trials unnecessary? Picking signal from noise. BMJ (2007) 6.77
Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials. BMJ (2003) 4.69
Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med (1999) 4.63
Blinded trials taken to the test: an analysis of randomized clinical trials that report tests for the success of blinding. Int J Epidemiol (2007) 3.54
Anecdotes that provide definitive evidence. BMJ (2006) 3.41
Active placebos versus antidepressants for depression. Cochrane Database Syst Rev (2004) 3.10
Industry sponsorship and financial conflict of interest in the reporting of clinical trials in psychiatry. Am J Psychiatry (2005) 3.05
Systems for grading the quality of evidence and the strength of recommendations II: pilot study of a new system. BMC Health Serv Res (2005) 2.91
Turning a blind eye: the success of blinding reported in a random sample of randomised, placebo controlled trials. BMJ (2004) 2.88
Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: a meta-analysis. Ann Fam Med (2005) 2.03
Comprehensive analysis of remission (COMPARE) with venlafaxine versus SSRIs. Biol Psychiatry (2007) 1.93
The prevalence of underpowered randomized clinical trials in rheumatology. J Rheumatol (2005) 1.92
A systematic review of newer pharmacotherapies for depression in adults: evidence report summary. Ann Intern Med (2000) 1.92
The missed lessons of Sir Austin Bradford Hill. Epidemiol Perspect Innov (2004) 1.63
Teleoanalysis: combining data from different types of study. BMJ (2003) 1.48
Helicobacter connections. ChemMedChem (2006) 1.29
Observational versus experimental studies: what's the evidence for a hierarchy? NeuroRx (2004) 1.23
Unity from diversity: the evidential use of anecdotal reports of adverse drug reactions and interactions. J Eval Clin Pract (2005) 1.23
Causal association in pharmacovigilance and pharmacoepidemiology: thoughts on the application of the Austin Bradford-Hill criteria. Drug Saf (2002) 1.13
Applying Bradford Hill's criteria for causation to neuropsychiatry: challenges and opportunities. J Neuropsychiatry Clin Neurosci (2001) 1.04
Idiopathic environmental intolerance: Part 1: A causation analysis applying Bradford Hill's criteria to the toxicogenic theory. Toxicol Rev (2003) 0.91
Publication bias in systematic reviews. Arch Gen Psychiatry (2007) 0.89
Idiopathic environmental intolerance: Part 2: A causation analysis applying Bradford Hill's criteria to the psychogenic theory. Toxicol Rev (2003) 0.88
Bradford-Hill Criteria provide the way ahead for controversial theory. Int J Surg (2005) 0.87
Application of the bradford hill criteria to assess the causality of cisapride-induced arrhythmia: a model for assessing causal association in pharmacovigilance. Drug Saf (2007) 0.81
Hempelian and Kuhnian approaches in the philosophy of medicine: the Semmelweis case. Stud Hist Philos Biol Biomed Sci (2005) 0.79
The multiple outcomes bias in antidepressants research. Med Hypotheses (2005) 0.78
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med (2008) 38.76
Avoidable waste in the production and reporting of research evidence. Lancet (2009) 12.28
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol (2010) 11.77
Cochrane systematic review of colorectal cancer screening using the fecal occult blood test (hemoccult): an update. Am J Gastroenterol (2008) 7.45
Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA (2010) 5.90
Antibiotics for acute otitis media: a meta-analysis with individual patient data. Lancet (2006) 5.83
Seventy-five trials and eleven systematic reviews a day: how will we ever keep up? PLoS Med (2010) 5.80
No surgical innovation without evaluation: the IDEAL recommendations. Lancet (2009) 5.57
A prescription for better prescribing. BMJ (2006) 5.31
Grading quality of evidence and strength of recommendations for diagnostic tests and strategies. BMJ (2008) 5.16
Ethics review roulette: what can we learn? BMJ (2004) 4.99
Cardiac impairment or heart failure? BMJ (2005) 4.67
Sicily statement on evidence-based practice. BMC Med Educ (2005) 4.47
How well does B-type natriuretic peptide predict death and cardiac events in patients with heart failure: systematic review. BMJ (2005) 4.31
Too much medicine; too little care. BMJ (2013) 3.90
An implementation research agenda. Implement Sci (2009) 3.77
A new taxonomy for describing and defining adherence to medications. Br J Clin Pharmacol (2012) 3.72
GRADE guidelines: 2. Framing the question and deciding on important outcomes. J Clin Epidemiol (2010) 3.60
All trials must be registered and the results published. BMJ (2013) 3.46
GRADE guidelines: 9. Rating up the quality of evidence. J Clin Epidemiol (2011) 3.30
Corticosteroids for pain relief in sore throat: systematic review and meta-analysis. BMJ (2009) 3.13
Evaluation and stages of surgical innovations. Lancet (2009) 3.04
GRADE guidelines: 7. Rating the quality of evidence--inconsistency. J Clin Epidemiol (2011) 3.02
Challenges in evaluating surgical innovation. Lancet (2009) 2.86
Case reports of suspected adverse drug reactions--systematic literature survey of follow-up. BMJ (2006) 2.79
The road to health care. BMJ (2004) 2.71
Anecdotes as evidence. BMJ (2003) 2.66
Follow-up of blood-pressure lowering and glucose control in type 2 diabetes. N Engl J Med (2014) 2.64
The paths from research to improved health outcomes. ACP J Club (2005) 2.61
Anticoagulation control and prediction of adverse events in patients with atrial fibrillation: a systematic review. Circ Cardiovasc Qual Outcomes (2008) 2.61
Hypertension guideline recommendations in general practice: awareness, agreement, adoption, and adherence. Br J Gen Pract (2007) 2.37
Whispered voice test for screening for hearing impairment in adults and children: systematic review. BMJ (2003) 2.36
General practitioners' self ratings of skills in evidence based medicine: validation study. BMJ (2002) 2.36
Teaching evidence based medicine. BMJ (2004) 2.36
Designing studies to ensure that estimates of test accuracy are transferable. BMJ (2002) 2.36
Comparative accuracy: assessing new tests against existing diagnostic pathways. BMJ (2006) 2.30
The automation of systematic reviews. BMJ (2013) 2.20
Early stopping of randomized clinical trials for overt efficacy is problematic. J Clin Epidemiol (2008) 2.18
Clarification of terminology in medication errors: definitions and classification. Drug Saf (2006) 2.06
How quickly should we titrate antihypertensive medication? Systematic review modelling blood pressure response from trial data. Heart (2011) 2.06
A child with earache. Are antibiotics the best treatment? Aust Fam Physician (2002) 2.03
Is the problem that everything is a diagnosis? Aust Fam Physician (2013) 1.96
GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes. J Clin Epidemiol (2012) 1.90
Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial. Diabetes Care (2009) 1.89
Systematic review automation technologies. Syst Rev (2014) 1.84
Using N-of-1 trials to improve patient management and save costs. J Gen Intern Med (2010) 1.80
The state of primary-care research. Lancet (2004) 1.76
GRADE guidelines: 12. Preparing summary of findings tables-binary outcomes. J Clin Epidemiol (2012) 1.75
Minimal interventions to decrease long-term use of benzodiazepines in primary care: a systematic review and meta-analysis. Br J Gen Pract (2011) 1.71
Lowering blood pressure reduces renal events in type 2 diabetes. J Am Soc Nephrol (2009) 1.68
Misunderstandings, misperceptions, and mistakes. ACP J Club (2007) 1.63
What should clinicians do when faced with conflicting recommendations? BMJ (2008) 1.62
A systematic review and meta-analysis: probiotics in the treatment of irritable bowel syndrome. BMC Gastroenterol (2009) 1.60
Compliance, concordance, adherence. Br J Clin Pharmacol (2007) 1.60
The GATE frame: critical appraisal with pictures. Evid Based Med (2006) 1.60
Acute infective conjunctivitis in primary care: who needs antibiotics? An individual patient data meta-analysis. Br J Gen Pract (2011) 1.59
Development and validation of decision rules to guide frequency of monitoring CD4 cell count in HIV-1 infection before starting antiretroviral therapy. PLoS One (2011) 1.58
Poor prescribing is continual. BMJ (2006) 1.55
Low-dose adrenaline, promethazine, and hydrocortisone in the prevention of acute adverse reactions to antivenom following snakebite: a randomised, double-blind, placebo-controlled trial. PLoS Med (2011) 1.53
Point-of-care testing for Hb A1c in the management of diabetes: a systematic review and metaanalysis. Clin Chem (2011) 1.53
Evidence based medicine and the medical curriculum. BMJ (2008) 1.52
Misunderstandings, misperceptions, and mistakes. Evid Based Med (2007) 1.51
Blood pressure self monitoring: questions and answers from a national conference. BMJ (2008) 1.49
Effects of pravastatin on coronary events in 2073 patients with low levels of both low-density lipoprotein cholesterol and high-density lipoprotein cholesterol: results from the LIPID study. Eur Heart J (2004) 1.46
A comparison of three different sources of data in assessing the frequencies of adverse reactions to amiodarone. Br J Clin Pharmacol (2004) 1.45
Medical research: Trial unpredictability yields predictable therapy gains. Nature (2013) 1.41
John Marshall's first description of surgical electrocautery. J R Soc Med (2011) 1.40
Evidence-based medicine teaching in UK medical schools. Med Teach (2009) 1.39
Quality of descriptions of treatments: a review of published randomised controlled trials. BMJ Open (2012) 1.39
Jacob Lockhart Clarke's and John Hughlings Jackson's first description of syringomyelia. J R Soc Med (2012) 1.39
The diagnosis of art: diastrophic dysplasia and Hephaistos. J R Soc Med (2006) 1.38
Frederick Treve's first surgical operation for appendicitis. J R Soc Med (2011) 1.38
Defining 'signal' and its subtypes in pharmacovigilance based on a systematic review of previous definitions. Drug Saf (2009) 1.35
Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: the ADVANCE trial. Circulation (2013) 1.32
Avoidable waste in the production and reporting of research evidence. Obstet Gynecol (2009) 1.32
Medication errors: problems and recommendations from a consensus meeting. Br J Clin Pharmacol (2009) 1.32
Better duplicate detection for systematic reviewers: evaluation of Systematic Review Assistant-Deduplication Module. Syst Rev (2015) 1.28
The rise of cholesterol testing: how much is unnecessary. Br J Gen Pract (2011) 1.27
NICE and new: appraising innovation. BMJ (2010) 1.26
Gold standards in pharmacovigilance: the use of definitive anecdotal reports of adverse drug reactions as pure gold and high-grade ore. Drug Saf (2007) 1.23
Blood pressure variables and cardiovascular risk: new findings from ADVANCE. Hypertension (2009) 1.22
Patterns of 'leakage' in the utilisation of clinical guidelines: a systematic review. Postgrad Med J (2011) 1.21
The scatter of research: cross sectional comparison of randomised trials and systematic reviews across specialties. BMJ (2012) 1.15
Use of evidence in hypertension guidelines: should we measure in both arms? Br J Gen Pract (2009) 1.14
Changing beta-blockers in heart failure: when is a class not a class? Br J Gen Pract (2008) 1.13
Problems and promises of innovation: why healthcare needs to rethink its love/hate relationship with the new. BMJ Qual Saf (2011) 1.12
Event rates, hospital utilization, and costs associated with major complications of diabetes: a multicountry comparative analysis. PLoS Med (2010) 1.09
Winding back the harms of too much medicine. BMJ (2013) 1.09
John Bostock's first description of hayfever. J R Soc Med (2011) 1.08
A novel case-control design to estimate the extent of over-diagnosis of breast cancer due to organised population-based mammography screening. Int J Cancer (2014) 1.08
Less is more: where do the abstracts in the EBM journal come from? Evid Based Med (2008) 1.08
Preventability of drug-related harms - part I: a systematic review. Drug Saf (2010) 1.08
GRADE: assessing the quality of evidence for diagnostic recommendations. Evid Based Med (2008) 1.08
General practitioners' use of different cardiovascular risk assessment strategies: a qualitative study. Med J Aust (2013) 1.07
Evidence-based mechanistic reasoning. J R Soc Med (2010) 1.06