Glucose-induced ubiquitylation and endocytosis of the yeast Jen1 transporter: role of lysine 63-linked ubiquitin chains.

PubWeight™: 1.15‹?› | Rank: Top 10%

🔗 View Article (PMC 2740547)

Published in J Biol Chem on May 11, 2009

Authors

Sandra Paiva1, Neide Vieira, Isabelle Nondier, Rosine Haguenauer-Tsapis, Margarida Casal, Danièle Urban-Grimal

Author Affiliations

1: Department of Biology, Molecular and Environmental Biology Centre, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. spaiva@bio.uminho.pt

Articles citing this

Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol (2009) 3.98

Arrestin-mediated endocytosis of yeast plasma membrane transporters. Traffic (2009) 1.74

The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics (2012) 1.73

A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination. J Cell Biol (2011) 1.59

How ubiquitin functions with ESCRTs. Traffic (2011) 1.51

Internal amino acids promote Gap1 permease ubiquitylation via TORC1/Npr1/14-3-3-dependent control of the Bul arrestin-like adaptors. Mol Cell Biol (2012) 1.32

A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis. Mol Cell Proteomics (2011) 1.25

A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis. J Cell Biol (2012) 1.24

Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes. J Biol Chem (2010) 1.13

Role of the ubiquitin system in regulating ion transport. Pflugers Arch (2010) 1.12

Endocytosis of the aspartic acid/glutamic acid transporter Dip5 is triggered by substrate-dependent recruitment of the Rsp5 ubiquitin ligase via the arrestin-like protein Aly2. Mol Cell Biol (2010) 1.03

A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting. Mol Biol Cell (2012) 1.00

Lysine 63-linked polyubiquitination is required for EGF receptor degradation. Proc Natl Acad Sci U S A (2013) 0.96

Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease. PLoS Genet (2014) 0.96

Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans. Mol Microbiol (2011) 0.95

Jen1p: a high affinity selenite transporter in yeast. Mol Biol Cell (2010) 0.91

Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans. Mol Microbiol (2009) 0.90

Sna3 is an Rsp5 adaptor protein that relies on ubiquitination for its MVB sorting. Traffic (2012) 0.90

Ubc13 and COOH terminus of Hsp70-interacting protein (CHIP) are required for growth hormone receptor endocytosis. J Biol Chem (2012) 0.89

SUMOylation regulates the SNF1 protein kinase. Proc Natl Acad Sci U S A (2013) 0.89

Versatile roles of k63-linked ubiquitin chains in trafficking. Cells (2014) 0.88

Defining an Embedded Code for Protein Ubiquitination. J Proteomics Bioinform (2009) 0.88

Regulation of clathrin-mediated endocytosis by dynamic ubiquitination and deubiquitination. Curr Biol (2014) 0.84

Integrated control of transporter endocytosis and recycling by the arrestin-related protein Rod1 and the ubiquitin ligase Rsp5. Elife (2014) 0.83

Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport. Biol Open (2012) 0.81

Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate. Oncotarget (2016) 0.77

The evolution of Jen3 proteins and their role in dicarboxylic acid transport in Yarrowia. Microbiologyopen (2014) 0.76

Choline transport activity regulates phosphatidylcholine synthesis through choline transporter Hnm1 stability. J Biol Chem (2013) 0.75

Improved α-Amylase Production by Dephosphorylation Mutation of CreD, an Arrestin-like Protein Required for Glucose-induced Endocytosis of Maltose Permease and Carbon Catabolite De-repression in Aspergillus oryzae. Appl Environ Microbiol (2017) 0.75

Yeast as a model system to study metabolic impact of selenium compounds. Microb Cell (2015) 0.75

Articles cited by this

Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res (1992) 34.33

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast (1994) 24.57

Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene (1995) 13.86

Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression. Nucleic Acids Res (1994) 10.72

A proteomics approach to understanding protein ubiquitination. Nat Biotechnol (2003) 10.51

Receptor downregulation and multivesicular-body sorting. Nat Rev Mol Cell Biol (2002) 10.12

Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell (2001) 9.08

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell (2009) 6.16

Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell (2008) 4.11

The genetic control of direct-repeat recombination in Saccharomyces: the effect of rad52 and rad1 on mitotic recombination at GAL10, a transcriptionally regulated gene. Genetics (1989) 4.00

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination. Mol Cell Biol (1995) 3.56

Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein. EMBO J (1997) 3.24

NPl1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase. Mol Microbiol (1995) 3.19

Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease. J Biol Chem (1996) 3.13

Endocytosis and degradation of the yeast uracil permease under adverse conditions. J Biol Chem (1994) 3.09

Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization. J Cell Biol (1998) 2.67

Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases. J Membr Biol (2000) 2.59

AMSH is an endosome-associated ubiquitin isopeptidase. J Cell Biol (2004) 2.58

Endocytosis: the DUB version. Trends Cell Biol (2006) 2.39

Ubiquitin is required for sorting to the vacuole of the yeast general amino acid permease, Gap1. J Biol Chem (2001) 2.22

Transport of lactate and other short-chain monocarboxylates in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol (1987) 2.09

Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1. EMBO Rep (2008) 2.03

Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane. J Cell Biol (2003) 1.92

Ubiquitin and endocytic internalization in yeast and animal cells. Biochim Biophys Acta (2004) 1.78

Regulation of receptors and transporters by ubiquitination: new insights into surprisingly similar mechanisms. Mol Interv (2007) 1.77

The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme. EMBO J (2005) 1.76

Direct sorting of the yeast uracil permease to the endosomal system is controlled by uracil binding and Rsp5p-dependent ubiquitylation. Mol Biol Cell (2003) 1.75

Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol Biol Cell (2003) 1.72

The deubiquitinating enzyme Ubp2 modulates Rsp5-dependent Lys63-linked polyubiquitin conjugates in Saccharomyces cerevisiae. J Biol Chem (2006) 1.68

Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling. J Cell Biol (2007) 1.65

The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo. J Cell Biol (2004) 1.62

A prenylation motif is required for plasma membrane localization and biochemical function of casein kinase I in budding yeast. J Biol Chem (1994) 1.58

A PEST-like sequence mediates phosphorylation and efficient ubiquitination of yeast uracil permease. Mol Cell Biol (1998) 1.58

The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1. J Bacteriol (1999) 1.55

NH4+-induced down-regulation of the Saccharomyces cerevisiae Gap1p permease involves its ubiquitination with lysine-63-linked chains. J Cell Sci (1999) 1.53

Casein kinase I-like protein kinases encoded by YCK1 and YCK2 are required for yeast morphogenesis. Mol Cell Biol (1993) 1.49

Mechanisms regulating the transport of acetic acid in Saccharomyces cerevisiae. Microbiology (1996) 1.46

Plasticity of polyubiquitin recognition as lysosomal targeting signals by the endosomal sorting machinery. Mol Biol Cell (2007) 1.37

Preferred in vivo ubiquitination sites. Bioinformatics (2004) 1.36

Casein kinase I-dependent phosphorylation within a PEST sequence and ubiquitination at nearby lysines signal endocytosis of yeast uracil permease. J Biol Chem (2000) 1.35

Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics (2007) 1.33

Regulation of copper-dependent endocytosis and vacuolar degradation of the yeast copper transporter, Ctr1p, by the Rsp5 ubiquitin ligase. Traffic (2007) 1.30

A novel multi-purpose cassette for repeated integrative epitope tagging of genes in Saccharomyces cerevisiae. Gene (2000) 1.30

The ubiquitin ligase Rsp5p is required for modification and sorting of membrane proteins into multivesicular bodies. Traffic (2004) 1.29

Amino acids regulate retrieval of the yeast general amino acid permease from the vacuolar targeting pathway. Mol Biol Cell (2006) 1.28

Targeting of Sna3p to the endosomal pathway depends on its interaction with Rsp5p and multivesicular body sorting on its ubiquitylation. Traffic (2007) 1.24

Site-specific mutagenesis by using an accurate recombinant polymerase chain reaction method. Anal Biochem (1996) 1.23

The role of ubiquitin in down-regulation and intracellular sorting of membrane proteins: insights from yeast. Biochim Biophys Acta (2003) 1.19

Transport of carboxylic acids in yeasts. FEMS Microbiol Rev (2008) 1.12

Multiple transcripts regulate glucose-triggered mRNA decay of the lactate transporter JEN1 from Saccharomyces cerevisiae. Biochem Biophys Res Commun (2005) 1.10

Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae. Yeast (2004) 1.08

Antagonistic roles of ESCRT and Vps class C/HOPS complexes in the recycling of yeast membrane proteins. Mol Biol Cell (2004) 1.04

Substrate- and ubiquitin-dependent trafficking of the yeast siderophore transporter Sit1. Traffic (2008) 1.04

GGA2- and ubiquitin-dependent trafficking of Arn1, the ferrichrome transporter of Saccharomyces cerevisiae. Mol Biol Cell (2007) 0.98

Expression of the lactate permease gene JEN1 from the yeast Saccharomyces cerevisiae. Fungal Genet Biol (2001) 0.92

Utilization of green fluorescent protein as a marker for studying the expression and turnover of the monocarboxylate permease Jen1p of Saccharomyces cerevisiae. Biochem J (2002) 0.92

Functional expression of the lactate permease Jen1p of Saccharomyces cerevisiae in Pichia pastoris. Biochem J (2003) 0.89

Articles by these authors

The ubiquitin code of yeast permease trafficking. Trends Cell Biol (2010) 1.92

Direct sorting of the yeast uracil permease to the endosomal system is controlled by uracil binding and Rsp5p-dependent ubiquitylation. Mol Biol Cell (2003) 1.75

Ubp3 requires a cofactor, Bre5, to specifically de-ubiquitinate the COPII protein, Sec23. Nat Cell Biol (2003) 1.70

Role of monocarboxylate transporters in human cancers: state of the art. J Bioenerg Biomembr (2012) 1.70

Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Mol Cell Biol (2006) 1.51

Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization. PLoS One (2010) 1.41

Ubiquitin ligase adaptors: regulators of ubiquitylation and endocytosis of plasma membrane proteins. Exp Cell Res (2008) 1.34

The ubiquitin ligase Rsp5p is required for modification and sorting of membrane proteins into multivesicular bodies. Traffic (2004) 1.29

Versatile role of the yeast ubiquitin ligase Rsp5p in intracellular trafficking. Biochem Soc Trans (2008) 1.27

A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis. Mol Cell Proteomics (2011) 1.25

Targeting of Sna3p to the endosomal pathway depends on its interaction with Rsp5p and multivesicular body sorting on its ubiquitylation. Traffic (2007) 1.24

A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis. J Cell Biol (2012) 1.24

Ear1p and Ssh4p are new adaptors of the ubiquitin ligase Rsp5p for cargo ubiquitylation and sorting at multivesicular bodies. Mol Biol Cell (2008) 1.14

Raft partitioning of the yeast uracil permease during trafficking along the endocytic pathway. Traffic (2003) 1.09

Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae. Yeast (2004) 1.08

Antagonistic roles of ESCRT and Vps class C/HOPS complexes in the recycling of yeast membrane proteins. Mol Biol Cell (2004) 1.04

Substrate- and ubiquitin-dependent trafficking of the yeast siderophore transporter Sit1. Traffic (2008) 1.04

The GTPase-activating enzyme Gyp1p is required for recycling of internalized membrane material by inactivation of the Rab/Ypt GTPase Ypt1p. Mol Cell Biol (2004) 1.04

Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family. Biochem Res Int (2012) 1.04

Yeast functional analysis: identification of two essential genes involved in ER to Golgi trafficking. Traffic (2003) 1.02

Ecological survey of Saccharomyces cerevisiae strains from vineyards in the Vinho Verde Region of Portugal. FEMS Microbiol Ecol (2005) 1.00

A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting. Mol Biol Cell (2012) 1.00

Survey of molecular methods for the typing of wine yeast strains. FEMS Microbiol Lett (2004) 0.99

Biodiversity of Saccharomyces yeast strains from grape berries of wine-producing areas using starter commercial yeasts. FEMS Yeast Res (2006) 0.99

Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type. BMC Cancer (2011) 0.98

Cytokinesis in yeast meiosis depends on the regulated removal of Ssp1p from the prospore membrane. EMBO J (2007) 0.98

Batch production of a silk-elastin-like protein in E. coli BL21(DE3): key parameters for optimisation. Microb Cell Fact (2013) 0.97

Mutants defective in secretory/vacuolar pathways in the EUROFAN collection of yeast disruptants. Yeast (2002) 0.96

Dissemination and survival of commercial wine yeast in the vineyard: a large-scale, three-years study. FEMS Yeast Res (2005) 0.96

Yeast Vps55p, a functional homolog of human obesity receptor gene-related protein, is involved in late endosome to vacuole trafficking. Mol Biol Cell (2002) 0.96

Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate. J Bioenerg Biomembr (2012) 0.95

Genetic characterization of commercial Saccharomyces cerevisiae isolates recovered from vineyard environments. Yeast (2007) 0.94

The genetic structure of fermentative vineyard-associated Saccharomyces cerevisiae populations revealed by microsatellite analysis. Antonie Van Leeuwenhoek (2007) 0.93

Genetic diversity and population structure of Saccharomyces cerevisiae strains isolated from different grape varieties and winemaking regions. PLoS One (2012) 0.93

Utilization of green fluorescent protein as a marker for studying the expression and turnover of the monocarboxylate permease Jen1p of Saccharomyces cerevisiae. Biochem J (2002) 0.92

The disruption of JEN1 from Candida albicans impairs the transport of lactate. Mol Membr Biol (2005) 0.92

Interaction of the deubiquitinating enzyme Ubp2 and the e3 ligase Rsp5 is required for transporter/receptor sorting in the multivesicular body pathway. PLoS One (2009) 0.92

Silk fibroin microparticles as carriers for delivery of human recombinant bone morphogenetic protein-2: in vitro and in vivo bioactivity. Tissue Eng Part C Methods (2010) 0.91

Tailoring cutinase activity towards polyethylene terephthalate and polyamide 6,6 fibers. J Biotechnol (2007) 0.91

Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans. Mol Microbiol (2009) 0.90

SATP (YaaH), a succinate-acetate transporter protein in Escherichia coli. Biochem J (2013) 0.89

Functional expression of the lactate permease Jen1p of Saccharomyces cerevisiae in Pichia pastoris. Biochem J (2003) 0.89

Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy. Traffic (2008) 0.89

Thermoresponsive self-assembled elastin-based nanoparticles for delivery of BMPs. J Control Release (2009) 0.89

Trafficking of siderophore transporters in Saccharomyces cerevisiae and intracellular fate of ferrioxamine B conjugates. Traffic (2007) 0.88

Suppression of tumorigenicity of rhabdoid tumor derived G401 cells by the multivalent HB-19 pseudopeptide that targets surface nucleolin. Biochimie (2010) 0.86

The use of genetically modified Saccharomyces cerevisiae strains in the wine industry. Appl Microbiol Biotechnol (2005) 0.86

Transport and cytotoxicity of the anticancer drug 3-bromopyruvate in the yeast Saccharomyces cerevisiae. J Bioenerg Biomembr (2012) 0.85

Yeast Rsp5 ubiquitin ligase affects the actin cytoskeleton in vivo and in vitro. Eur J Cell Biol (2011) 0.84

The conserved sequence NXX[S/T]HX[S/T]QDXXXT of the lactate/pyruvate:H(+) symporter subfamily defines the function of the substrate translocation pathway. Mol Membr Biol (2007) 0.83

Gex1 is a yeast glutathione exchanger that interferes with pH and redox homeostasis. Mol Biol Cell (2011) 0.83

Engineered Thermobifida fusca cutinase with increased activity on polyester substrates. Biotechnol J (2011) 0.83

Lactic acid production in Saccharomyces cerevisiae is modulated by expression of the monocarboxylate transporters Jen1 and Ady2. FEMS Yeast Res (2012) 0.83

Heterologous expression of a plant uracil transporter in yeast: improvement of plasma membrane targeting in mutants of the Rsp5p ubiquitin protein ligase. Biotechnol J (2006) 0.81

Heterologous expression of mammalian Na/H antiporters in Saccharomyces cerevisiae. Biochim Biophys Acta (2006) 0.81

A mechanism for protein monoubiquitination dependent on a trans-acting ubiquitin-binding domain. J Biol Chem (2013) 0.81

Functional analysis of Kluyveromyces lactis carboxylic acids permeases: heterologous expression of KlJEN1 and KlJEN2 genes. Curr Genet (2007) 0.80

High level expression and facile purification of recombinant silk-elastin-like polymers in auto induction shake flask cultures. AMB Express (2013) 0.79

The transport of carboxylic acids and important role of the Jen1p transporter during the development of yeast colonies. Biochem J (2013) 0.79

Deficiency of Pkc1 activity affects glycerol metabolism in Saccharomyces cerevisiae. FEMS Yeast Res (2005) 0.78

A substrate translocation trajectory in a cytoplasm-facing topological model of the monocarboxylate/H⁺ symporter Jen1p. Mol Microbiol (2011) 0.78

Expression of the functional carbohydrate-binding module (CBM) of human laforin. Protein Expr Purif (2010) 0.78

Biochemical and molecular characterization of Saccharomyces cerevisiae strains obtained from sugar-cane juice fermentations and their impact in cachaça production. Appl Environ Microbiol (2007) 0.78

Electrospun silk-elastin-like fibre mats for tissue engineering applications. Biomed Mater (2013) 0.78

High level biosynthesis of a silk-elastin-like protein in E. coli. Biomacromolecules (2014) 0.77

A deubiquitylating complex required for neosynthesis of a yeast mitochondrial ATP synthase subunit. PLoS One (2012) 0.77

Azo reductase activity of intact saccharomyces cerevisiae cells is dependent on the Fre1p component of plasma membrane ferric reductase. Appl Environ Microbiol (2005) 0.77

Functionalization of cellulose acetate fibers with engineered cutinases. Biotechnol Prog (2010) 0.77

Odorant binding proteins: a biotechnological tool for odour control. Appl Microbiol Biotechnol (2013) 0.76

Plasmids for in vivo construction of integrative Candida albicans vectors in Saccharomyces cerevisiae. Yeast (2010) 0.76

Proteolytic enzyme engineering: a tool for wool. Biomacromolecules (2009) 0.75

Elastin-based nanoparticles for delivery of bone morphogenetic proteins. Methods Mol Biol (2012) 0.75

Development of elastin-like recombinamer films with antimicrobial activity. Biomacromolecules (2015) 0.75