Published in Mol Microbiol on October 01, 1995
Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination. EMBO J (1997) 4.01
The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. EMBO J (1998) 3.54
A family of ammonium transporters in Saccharomyces cerevisiae. Mol Cell Biol (1997) 3.49
Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein. EMBO J (1997) 3.24
The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae. EMBO J (1998) 3.09
Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast. J Cell Biol (1999) 2.80
The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast. Mol Biol Cell (1999) 2.73
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Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization. J Cell Biol (1998) 2.67
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Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis. J Cell Biol (1998) 2.43
Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast. Mol Cell Biol (2004) 2.26
Functional domains of the Rsp5 ubiquitin-protein ligase. Mol Cell Biol (1999) 2.15
Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome. J Clin Invest (1999) 2.15
The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase. Proc Natl Acad Sci U S A (1997) 2.09
Nitrogen-regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae. Mol Biol Cell (1998) 2.07
Ubiquitination of the yeast a-factor receptor. J Cell Biol (1996) 2.06
Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome. EMBO J (2009) 1.93
Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins. EMBO J (2004) 1.92
K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway. J Cell Biol (2009) 1.90
The yeast actin-related protein Arp2p is required for the internalization step of endocytosis. Mol Biol Cell (1997) 1.83
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions. Cell Death Differ (2010) 1.77
The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme. EMBO J (2005) 1.76
Direct sorting of the yeast uracil permease to the endosomal system is controlled by uracil binding and Rsp5p-dependent ubiquitylation. Mol Biol Cell (2003) 1.75
The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics (2012) 1.73
Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol Biol Cell (2003) 1.72
Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase. Mol Cell Biol (2001) 1.69
Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.66
Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination. Proc Natl Acad Sci U S A (1999) 1.63
NEDD4L overexpression rescues the release and infectivity of human immunodeficiency virus type 1 constructs lacking PTAP and YPXL late domains. J Virol (2008) 1.60
Amino acid signaling in yeast: casein kinase I and the Ssy5 endoprotease are key determinants of endoproteolytic activation of the membrane-bound Stp1 transcription factor. Mol Cell Biol (2004) 1.59
A PEST-like sequence mediates phosphorylation and efficient ubiquitination of yeast uracil permease. Mol Cell Biol (1998) 1.58
A novel mechanism of ion homeostasis and salt tolerance in yeast: the Hal4 and Hal5 protein kinases modulate the Trk1-Trk2 potassium transporter. Mol Cell Biol (1999) 1.53
Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids. Mol Cell Biol (2001) 1.49
In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation. Mol Cell Biol (2001) 1.47
The linker region of the ABC-transporter Ste6 mediates ubiquitination and fast turnover of the protein. EMBO J (1997) 1.45
Morphology of the yeast endocytic pathway. Mol Biol Cell (1998) 1.43
MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution, is identical to the ubiquitin-protein ligase gene RSP5. Genetics (1997) 1.41
Transcriptional induction by aromatic amino acids in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.38
Recruitment of the ESCRT machinery to a putative seven-transmembrane-domain receptor is mediated by an arrestin-related protein. Mol Cell Biol (2009) 1.37
Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway. Mol Cell Biol (2001) 1.34
Internal amino acids promote Gap1 permease ubiquitylation via TORC1/Npr1/14-3-3-dependent control of the Bul arrestin-like adaptors. Mol Cell Biol (2012) 1.32
A large PEST-like sequence directs the ubiquitination, endocytosis, and vacuolar degradation of the yeast a-factor receptor. J Cell Biol (1998) 1.29
Uptake of the ATP-binding cassette (ABC) transporter Ste6 into the yeast vacuole is blocked in the doa4 Mutant. Mol Biol Cell (2001) 1.27
Uracil-induced down-regulation of the yeast uracil permease. J Bacteriol (1999) 1.26
Targeting of Sna3p to the endosomal pathway depends on its interaction with Rsp5p and multivesicular body sorting on its ubiquitylation. Traffic (2007) 1.24
A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis. J Cell Biol (2012) 1.24
Opposing activities of the Snx3-retromer complex and ESCRT proteins mediate regulated cargo sorting at a common endosome. Mol Biol Cell (2008) 1.21
Suppressors of ssy1 and ptr3 null mutations define novel amino acid sensor-independent genes in Saccharomyces cerevisiae. Genetics (2001) 1.17
Evidence for coupled biogenesis of yeast Gap1 permease and sphingolipids: essential role in transport activity and normal control by ubiquitination. Mol Biol Cell (2007) 1.16
Glucose-induced ubiquitylation and endocytosis of the yeast Jen1 transporter: role of lysine 63-linked ubiquitin chains. J Biol Chem (2009) 1.15
Rsp5p, a new link between the actin cytoskeleton and endocytosis in the yeast Saccharomyces cerevisiae. Mol Cell Biol (2002) 1.14
Role of the ubiquitin system in regulating ion transport. Pflugers Arch (2010) 1.12
WW domains of Rsp5p define different functions: determination of roles in fluid phase and uracil permease endocytosis in Saccharomyces cerevisiae. Genetics (2001) 1.12
Copper transport activity of yeast Ctr1 is down-regulated via its C terminus in response to excess copper. J Biol Chem (2008) 1.12
Saccharomyces cerevisiae sigma 1278b has novel genes of the N-acetyltransferase gene superfamily required for L-proline analogue resistance. J Bacteriol (2000) 1.10
Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cells. Mol Cell Biol (2007) 1.08
Abnormal development of the neuromuscular junction in Nedd4-deficient mice. Dev Biol (2009) 1.08
A nonconserved Ala401 in the yeast Rsp5 ubiquitin ligase is involved in degradation of Gap1 permease and stress-induced abnormal proteins. Proc Natl Acad Sci U S A (2003) 1.06
The external amino acid signaling pathway promotes activation of Stp1 and Uga35/Dal81 transcription factors for induction of the AGP1 gene in Saccharomyces cerevisiae. Genetics (2004) 1.04
Glucose-induced monoubiquitination of the Saccharomyces cerevisiae galactose transporter is sufficient to signal its internalization. J Bacteriol (2001) 1.02
Yeast glycogen synthase kinase 3 is involved in protein degradation in cooperation with Bul1, Bul2, and Rsp5. Mol Cell Biol (2000) 1.02
Functional expression, quantification and cellular localization of the Hxt2 hexose transporter of Saccharomyces cerevisiae tagged with the green fluorescent protein. Biochem J (1999) 1.02
Split-ubiquitin two-hybrid assay to analyze protein-protein interactions at the endosome: application to Saccharomyces cerevisiae Bro1 interacting with ESCRT complexes, the Doa4 ubiquitin hydrolase, and the Rsp5 ubiquitin ligase. Eukaryot Cell (2007) 1.02
Structural involvement in substrate recognition of an essential aspartate residue conserved in Mep/Amt and Rh-type ammonium transporters. Curr Genet (2006) 1.01
Sequential use of nitrogen compounds by Saccharomyces cerevisiae during wine fermentation: a model based on kinetic and regulation characteristics of nitrogen permeases. Appl Environ Microbiol (2012) 1.01
A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting. Mol Biol Cell (2012) 1.00
Gga2 mediates sequential ubiquitin-independent and ubiquitin-dependent steps in the trafficking of ARN1 from the trans-Golgi network to the vacuole. J Biol Chem (2009) 0.99
Actin and endocytosis in budding yeast. Genetics (2015) 0.99
CAC3(MSI1) suppression of RAS2(G19V) is independent of chromatin assembly factor I and mediated by NPR1. Mol Cell Biol (2001) 0.98
Down-regulation of a manganese transporter in the face of metal toxicity. Mol Biol Cell (2009) 0.96
Ubiquitin metabolism affects cellular response to volatile anesthetics in yeast. Mol Cell Biol (1999) 0.95
The HECT domain of the ubiquitin ligase Rsp5 contributes to substrate recognition. J Biol Chem (2009) 0.95
Moderate concentrations of ethanol inhibit endocytosis of the yeast maltose transporter. Appl Environ Microbiol (1997) 0.94
Systematic mutational analysis of the intracellular regions of yeast Gap1 permease. PLoS One (2011) 0.93
Ammonia-specific regulation of Gln3 localization in Saccharomyces cerevisiae by protein kinase Npr1. J Biol Chem (2006) 0.93
Internal trehalose protects endocytosis from inhibition by ethanol in Saccharomyces cerevisiae. Appl Environ Microbiol (2000) 0.92
Key role for intracellular K+ and protein kinases Sat4/Hal4 and Hal5 in the plasma membrane stabilization of yeast nutrient transporters. Mol Cell Biol (2007) 0.92
Volatile anesthetics affect nutrient availability in yeast. Genetics (2002) 0.92
The Tsc/Rheb signaling pathway controls basic amino acid uptake via the Cat1 permease in fission yeast. Mol Genet Genomics (2008) 0.92
Stress conditions promote yeast Gap1 permease ubiquitylation and down-regulation via the arrestin-like Bul and Aly proteins. J Biol Chem (2014) 0.92
Interaction of the deubiquitinating enzyme Ubp2 and the e3 ligase Rsp5 is required for transporter/receptor sorting in the multivesicular body pathway. PLoS One (2009) 0.92
Quality control: quality control at the plasma membrane: one mechanism does not fit all. J Cell Biol (2014) 0.91
Rsp5 ubiquitin ligase modulates translation accuracy in yeast Saccharomyces cerevisiae. RNA (2005) 0.90
The yeast tumor suppressor homologue Sro7p is required for targeting of the sodium pumping ATPase to the cell surface. Mol Biol Cell (2006) 0.90
Versatile roles of k63-linked ubiquitin chains in trafficking. Cells (2014) 0.88
AgtA, the dicarboxylic amino acid transporter of Aspergillus nidulans, is concertedly down-regulated by exquisite sensitivity to nitrogen metabolite repression and ammonium-elicited endocytosis. Eukaryot Cell (2009) 0.87
The essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4. J Biol Chem (2011) 0.87
Substrate-induced ubiquitylation and endocytosis of yeast amino acid permeases. Mol Cell Biol (2014) 0.87
2-Deoxyglucose impairs Saccharomyces cerevisiae growth by stimulating Snf1-regulated and α-arrestin-mediated trafficking of hexose transporters 1 and 3. Mol Cell Biol (2014) 0.87
Amino acid signaling in yeast: post-genome duplication divergence of the Stp1 and Stp2 transcription factors. J Biol Chem (2009) 0.86
Genes encoding ribosomal proteins Rps0A/B of Saccharomyces cerevisiae interact with TOM1 mutants defective in ribosome synthesis. Genetics (2001) 0.84
Clathrin and two components of the COPII complex, Sec23p and Sec24p, could be involved in endocytosis of the Saccharomyces cerevisiae maltose transporter. J Bacteriol (1999) 0.84
Converting the yeast arginine can1 permease to a lysine permease. J Biol Chem (2014) 0.84
Endocytic regulation of alkali metal transport proteins in mammals, yeast and plants. Curr Genet (2013) 0.84
Transcription-coupled repair in yeast is independent from ubiquitylation of RNA pol II: implications for Cockayne's syndrome. Proc Natl Acad Sci U S A (2000) 0.83
The SAGA histone acetyltransferase complex regulates leucine uptake through the Agp3 permease in fission yeast. J Biol Chem (2012) 0.82
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